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showing 10 items of 385 documents

High Lipid Content of Prey Fish and n−3 PUFA Peroxidation Impair the Thiamine Status of Feeding-Migrating Atlantic Salmon (Salmo salar) and Is Reflec…

2022

Signs of impaired thiamine (vitamin B1) status in feeding-migrating Atlantic salmon (Salmo salar) were studied in three Baltic Sea areas, which differ in the proportion and nutritional composition of prey fish sprat (Sprattus sprattus) and herring (Clupea harengus). The concentration of n−3 polyunsaturated fatty acids (n−3 PUFAs) increased in salmon with dietary lipids and n−3 PUFAs, and the hepatic peroxidation product malondialdehyde (MDA) concentration increased exponentially with increasing n−3 PUFA and docosahexaenoic acid (DHA, 22:6n−3) concentration, whereas hepatic total thiamine concentration, a sensitive indicator of thiamine status, decreased with th…

malondialdehydeREPRODUCTIVE DISORDERBaltic SeaSPRAT SPRATTUS-SPRATTUSherring Clupea harengusspratsprat Sprattus sprattussilli (laji)METABOLISMlipiditBiochemistryatlantinlohiDIETthiaminerasva-aineenvaihduntapuutostilatravintototal lipidstiamiiniOXIDATIVE STRESSMolecular Biologyoksidatiivinen stressivaelluskalatmalonialdehydifood and beveragessalmonlipid peroxidationHERRING CLUPEA-HARENGUSDEFICIENCYM74 syndromeherringAtlantic salmon Salmo salarAtlantic salmon <i>Salmo salar</i>; Baltic Sea; herring <i>Clupea harengus</i>; lipid peroxidation; M74 syndrome; malondialdehyde; polyunsaturated fatty acids; sprat <i>Sprattus sprattus</i>; thiamine; total lipids1182 Biochemistry cell and molecular biologykilohaililipids (amino acids peptides and proteins)FATTY-ACIDShuman activitiespolyunsaturated fatty acids
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¿Es necesaria la quimio-radioterapia preoperatoria en todos los pacientes con cáncer del recto localmente avanzado? Análisis de una serie consecutiva…

2013

Antecedentes: actualmente la quimio-radioterapia preoperatoria es el método estándar de tratamiento de los pacientes con cáncer del recto localmente avanzado. Sin embargo, a partir de la estandarización de la técnica de la escisión total del mesorrecto, las recidivas locales se han reducido significativamente y algunos pacientes podrían evitar el sobretratamiento con quimio-radioterapia preoperatoria y su potencial efecto tóxico. El presente estudio ha sido diseñado con el objetivo de evaluar los factores predictivos de recidiva en una serie institucional de pacientes con cáncer rectal estadificado preoperatoriamente con ecografía rectal y/o resonancia magnética como cT2N+ o cT3 y tratados …

margen de resección crcunferencialestadificación preoperatoriaUNESCO::CIENCIAS MÉDICAS:CIENCIAS MÉDICAS::Cirugía::Cirugía abdominal [UNESCO]escisión total del mesorrectoUNESCO::CIENCIAS MÉDICAS::Cirugía::Cirugía abdominal:CIENCIAS MÉDICAS [UNESCO]cáncer rectaltratamiento neoadjuvante
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Global Chronic Total Occlusion Crossing Algorithm

2021

© 2021 The Authors. Published by Elsevier on behalf of the American College of Cardiology Foundation. This is an open access article under the CC By-NC-ND License (http://creativecommons.org/licenses/by-nc-nd/4)

medicine.diagnostic_testAlgoritmosbusiness.industrymedicine.medical_treatmentPercutaneous coronary interventionGlobalState of the art reviewCollateral circulationTotal occlusionPercutaneous coronary interventionCatheterChronic total occlusionCoronary OcclusionIntravascular ultrasoundOcclusionAngiographyTreatment algorithmMedicineOclusão CoronáriaCardiology and Cardiovascular MedicinebusinessAlgorithmAlgorithms
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Dual lumen microcatheters for recanalisation of chronic total occlusions: A EuroCTO Club expert panel report

2021

Dual lumen microcatheters (DLMC) have become indispensable tools in the setting of percutaneous coronary intervention (PCI) of chronic total occlusion (CTO). Other than allowing preservation and treatment of bifurcated coronary branches within or in the proximity of the CTO-body, they enable the use of modified parallel wiring, antegrade dissection and re-entry, collateral selection and retrograde negotiation of the distal CTO-cap. This Euro-CTO consensus document describes current DLMCs and suggests a practical guide to anatomies and techniques in which these devices are applicable.

medicine.medical_specialtyChronic coronary total occlusionOther techniquebusiness.industrymedicine.medical_treatmentLumen (anatomy)Percutaneous coronary interventionDissection (medical)medicine.diseaseTotal occlusionPanel reportPercutaneous Coronary InterventionExpert ConsensusConventional PCImedicineHumansBifurcationRadiologyCardiology and Cardiovascular MedicinebusinessHuman
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Towards the Point of Care and Noninvasive Classification of Bladder Cancer from Urine Sediment Infrared Spectroscopy. Spectral differentiation of nor…

2021

Abstract Bladder cancer (BC) is the 9th cancer cause of death and one of most cost-intensive in the world. The diagnostic tools are still not at all satisfactory. Herein we evaluated the potential of infrared spectroscopy to detect molecular changes that precede and accompany the carcinogenesis in voided urine sediment. We collected 165 samples from patients being diagnosed for BC and measured them with attenuated total reflectance Fourier transformed infrared spectroscopy (ATR FTIR). Samples were primarily divided into three groups according to cytology that indicated the presence of normal, abnormal and cancer cells. ATR FTIR spectra of sediments were analyzed with the use of partial leas…

medicine.medical_specialtyInfrared spectroscopy02 engineering and technology01 natural sciencesGastroenterologyAnalytical ChemistryInternal medicineCytologyurine sedimentmedicineMedicine and Health Sciencesreflection (ATR)infrared spectroscopySpectroscopyBladder cancerbusiness.industry010401 analytical chemistryCancerHistologyGold standard (test)Point-of-Care analysis021001 nanoscience & nanotechnologymedicine.disease3. Good health0104 chemical sciencesAttenuated total reflectionCancer cellbladder cancer0210 nano-technologybusiness
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Coplanar Indirect-Navigated Intraoperative Ultrasound: Matching Un-navigated Probes With Neuronavigation During Neurosurgical Procedures. How We Do I…

2021

BACKGROUND Intraoperative ultrasound (IOUS) is becoming more and more adopted in neurosurgery, since it has been associated to greater extent of resection (EOR) and to gross total resection (GTR) during brain tumor surgery. IOUS main limitations are spatial resolution, width and orientation of the field of view and scan quality, which are operator-dependent. Furthermore, most neurosurgeons are not confident with this technique, which needs a long learning curve in order to identify and interpret anatomic structures. OBJECTIVE To describe an effective procedure to take advantages of both IOUS and neuronavigation in case of lack of a navigated ultrasound system. METHODS We propose a reliable …

medicine.medical_specialtyIntraoperative ultrasoundNeuronavigationbusiness.industryOrientation (computer vision)Brain NeoplasmsUltrasoundExtent of resectionGross Total ResectionBrain tumorsNeurosurgical ProceduresIntraoperative ultrasoundNavigated intraoperative ultrasoundUltrasoundmedicineHumansSurgeryMedical physicsIOUSNeurology (clinical)UltrasonographybusinessNeuronavigationBrain tumor surgeryUltrasonographyOperative neurosurgery (Hagerstown, Md.)
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Differences in patients and lesion and procedure characteristics depending on the age of the coronary chronic total occlusion

2018

Introduction: Whether duration of chronic total occlusion (CTO) affects lesion and procedural characteristics remains largely unknown. Aim: To investigate whether CTO duration influences lesion characteristics and revascularization success. Material and methods: EuroCTO Registry data on patients who had CTO percutaneous coronary intervention between January 2015 and April 2017 were analyzed. Three groups were created based on occlusion age: 3 to 6 months (n = 1415), 7 to 12 months (n = 973), &gt; 12 months (n = 1656). Results: Patients with greater CTO duration were older (63.0 (56.0–70.0); 63.0 (56.0–71.0); 66.0 (59.0–73.0) years respectively; p &lt; 0.001), had more 3-vessel disease (32.2…

medicine.medical_specialtyMultivariate analysismedicine.medical_treatmentlcsh:Medicine030204 cardiovascular system & hematologyRevascularizationlesion characteristicsPercutaneous coronary intervention.Lesion03 medical and health sciences0302 clinical medicineInternal medicineOcclusionMedicine030212 general & internal medicineLesion characteristicAdverse effectchronic total occlusionOriginal Paperbusiness.industrypercutaneous coronary interventionlcsh:RPercutaneous coronary interventionCollateral circulationmedicine.anatomical_structureCardiologymedicine.symptomCardiology and Cardiovascular MedicinebusinessArtery
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Update in the Percutaneous Management of Coronary Chronic Total Occlusions

2018

Percutaneous coronary intervention (PCI) for chronic total occlusions (CTOs) has been rapidly evolving during recent years. With improvement in equipment and techniques, high success rates can be achieved at experienced centers, although overall success rates remain low. Prospective, randomized-controlled data regarding optimal use and indications for CTO PCI remain limited. CTO PCI should be performed when the anticipated benefit exceeds the potential risk. New high-quality studies of the clinical outcomes and techniques of CTO PCI are needed, as is the expansion of expert centers and operators that can achieve excellent clinical outcomes in this challenging patient and lesion subgroup. In…

medicine.medical_specialtyPercutaneousbusiness.industryPotential riskmedicine.medical_treatmentTreatment outcomePercutaneous coronary intervention030204 cardiovascular system & hematologyCABG = coronary artery bypass grafting CTA = computed tomography angiography CTO = chronic total occlusion IVUS = intravascular ultrasound MACE = major adverse cardiac event(s) MT = medical therapy OMT = optimal medical therapy PCI = percutaneous coronary intervention03 medical and health sciencessurgical procedures operative0302 clinical medicineChronic diseaseCoronary occlusionConventional PCImedicinecardiovascular diseases030212 general & internal medicineCardiology and Cardiovascular MedicinebusinessProspective cohort studyIntensive care medicine
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Utility of Intravascular Ultrasound in Percutaneous Revascularization of Chronic Total Occlusions

2016

Intravascular ultrasound has been used for &gt;20 years to guide percutaneous coronary intervention in different subsets of coronary lesions. During the last decade, the interest in percutaneous coronary intervention for chronic total occlusion (CTO) has increased dramatically, leading to high success rates. Failure of guidewire crossing is the most common reason for failed CTO attempts. Certain angiographic features, such as blunt proximal CTO cap, tortuosity, heavy calcification, and lack of visibility of path in the distal vessel, increase procedural difficulty. A better understanding of the behavior of the guidewire within the CTO segment may represent a key issue to achieve successful …

medicine.medical_specialtyPercutaneousmedicine.diagnostic_testbusiness.industrymedicine.medical_treatmentPercutaneous coronary intervention030204 cardiovascular system & hematologyRevascularizationTotal occlusionSettore MED/11 - Malattie Dell'Apparato Cardiovascolare03 medical and health sciences0302 clinical medicineBluntInternal medicineCTO = chronic total occlusion DES = drug-eluting stents IVUS = intravascular ultrasound MACE = major adverse cardiac event(s) PCI = percutaneous coronary interventionIntravascular ultrasoundConventional PCImedicineCardiology030212 general & internal medicineRadiologyCardiology and Cardiovascular MedicinebusinessMace
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PS01.057: THYROIDECTOMY AND LARYNGO-PHARYNGEAL REFLUX: WHAT’S NEW

2018

Abstract Background ‘Local neck symptoms’ may be related to goiter; a persistence of those symptoms after an uncomplicated total thyroidectomy (TT) might be referred to the laryngo-pharyngeal reflux (LPR). Our previous study found a correlation between goiter and LPR in selected patients with local neck symptoms; the purpose of our current study is to investigate the presence of a laringopharyngitis in patients with goiter, before and after TT, even in the absence of local neck symptoms, assessing whether the presence of LPR may play a role at the outset of the symptomatology. Methods Two groups of patients were considered and they differred for the presence or absence of local neck symptom…

medicine.medical_specialtyPharyngeal refluxbusiness.industrymedicine.medical_treatmentLaryngo-pharyngeal reflux Total ThyroidectomyGastroenterologyThyroidectomymedicineGeneral MedicinebusinessSurgery
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