Search results for " Traditional"

showing 10 items of 149 documents

Inhibition of Trypanosoma cruzi growth by medical plant extracts

2002

This study describes the screening of extracts obtained from 18 plants and two fungi used in the Chinese and Mediterranean traditional medicines on epimastigote forms of Trypanosoma cruzi. The extracts were tested against epimastigote of T. cruzi Bra C15C2 clone in vitro at 27 degrees C and at a concentration of 250 microg/ml in axenic culture. Angelica dahurica, A. pubescens, A. sinensis, Astragalus membranaceus, Coptis chinensis, Haplophyllum hispanicum, Phellodendron amurense, Poria cocos, Ranunculus sceleratus and Scutellaria baicalensis showed significant effects against the parasite with a percentage of growth inhibition between 20 and 100%. C. chinensis and R. sceleratus showed the g…

MaleTrypanosoma cruziPharmacognosyInhibitory Concentration 50chemistry.chemical_compoundDrug DiscoveryLeukocytesAnimalsRanunculus sceleratusMedicine Chinese TraditionalRats WistarTrypanosoma cruziPharmacologyPlants MedicinalDose-Response Relationship DrugbiologyTraditional medicineMediterranean RegionPlant ExtractsAngelica dahuricaFungiGeneral MedicineAstragalus propinquusCoptis chinensisbiology.organism_classificationRatsLogistic ModelschemistryPhellodendron amurenseScutellaria baicalensisMedicine TraditionalGrowth inhibitionFitoterapia
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Antioxidant activity of anti-inflammatory plant extracts

2002

The antioxidant properties of twenty medical herbs used in the traditional Mediterranean and Chinese medicine were studied. Extracts from Forsythia suspensa, Helichrysum italicum, Scrophularia auriculata, Inula viscosa, Coptis chinensis, Poria cocos and Scutellaria baicalensis had previously shown anti-inflammatory activity in different experimental models. Using free radical-generating systems H. italicum. I. viscosa and F. suspensa protected against enzymatic and non-enzymatic lipid peroxidation in model membranes and also showed scavenging property on the superoxide radical. All extracts were assayed at a concentration of 100 microg/ml. Most of the extracts were weak scavengers of the hy…

MaleXanthine OxidaseErythrocytesAntioxidantmedicine.drug_classmedicine.medical_treatmentHelichrysum italicumAntioxidantsGeneral Biochemistry Genetics and Molecular BiologyAnti-inflammatoryRats Sprague-DawleyLipid peroxidationchemistry.chemical_compoundmedicineAnimalsGeneral Pharmacology Toxicology and PharmaceuticsXanthine oxidaseForsythia suspensaPlants MedicinalbiologyTraditional medicineDeoxyribosePlant ExtractsAnti-Inflammatory Agents Non-SteroidalFree Radical ScavengersGeneral MedicineCoptis chinensisbiology.organism_classificationRatsBiochemistrychemistryMicrosomes LiverScutellaria baicalensisLipid PeroxidationMedicine TraditionalAminopyrine N-DemethylaseLife Sciences
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Modulation of P450 enzymes by Cuban natural products rich in polyphenolic compounds in rat hepatocytes.

2008

This paper reports cytotoxic effects and changes in the P450 system after exposing rat hepatocytes to four polyphenol-rich products widely used in Cuban traditional medicine (Mangifera indica L. (MSBE), Thalassia testudinum (Tt), Erythroxylum minutifolium and confusum extracts). Effects of mangiferin, the main polyphenol in MSBE, were also evaluated. Cytotoxicity was assayed by the MTT test after exposure of cells to the products (50-1000 microg/mL) for 24 or 72 h. The results showed that 500 microg/mL MSBE was moderately cytotoxic after 72 h, while mangiferin was not. Marked reductions in cell viability were produced by Erythroxylum extracts at concentrationsor = 200 microg/mL, whereas onl…

MaleXanthonesToxicologyRats Sprague-Dawleychemistry.chemical_compoundCytochrome P-450 Enzyme SystemmedicineAnimalsMangiferaMangiferinCells CulturedBiological ProductsMangiferabiologyTraditional medicineMolecular StructureChemistryPlant ExtractsCYP1A2CubaGeneral MedicineCYP2E1biology.organism_classificationErythroxylumRatsPolyphenolPhenacetinChlorzoxazoneHepatocytesMedicine Traditionalmedicine.drugChemico-biological interactions
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Global variation in anastomosis and end colostomy formation following left-sided colorectal resection

2019

Background: End colostomy rates following colorectal resection vary across institutions in high-income settings, being influenced by patient, disease, surgeon and system factors. This study aimed to assess global variation in end colostomy rates after left-sided colorectal resection. Methods: This study comprised an analysis of GlobalSurg-1 and -2 international, prospective, observational cohort studies (2014, 2016), including consecutive adult patients undergoing elective or emergency left-sided colorectal resection within discrete 2-week windows. Countries were grouped into high-, middle- and low-income tertiles according to the United Nations Human Development Index (HDI). Factors associ…

Malemodelos logísticosmedicine.medical_treatmenthumanossurgial careColorectal Neoplasmpaíses desarrolladosLogistic regressionoutcomesGlobal Healthurgencias médicas0302 clinical medicinepaíses en desarrolloSurgicalestudios prospectivosColostomy80 and overglobalsurg030212 general & internal medicineProspective StudiesProspective cohort studyMultivariate Analysimediana edadCancerAged 80 and overEmergencieancianoAnastomosis colorectal resection colostomyAnastomosis SurgicalColostomyGeneral MedicineMiddle Agedadultocolostomy; colorectal cancer; human developlment index3. Good healthColo-Rectal Cancertraditional healersElective Surgical Procedures030220 oncology & carcinogenesisFemaleColorectal Neoplasms6.4 Surgerylow incomeCohort studyHumanDeveloped CountrieAdultAdult; Aged; Aged 80 and over; Anastomosis Surgical; Colorectal Neoplasms; Colostomy; Elective Surgical Procedures; Emergencies; Female; Global Health; Humans; Logistic Models; Male; Middle Aged; Multivariate Analysis; Prospective Studies; Developed Countries; Developing Countriesmedicine.medical_specialtyneoplasias colorrectalesLogistic Modelcancer anastomosis surgical income stomas colostomy procedure colorectal resection end colostomy emergency surgical procedure human development indexdelayAnastomosishuman developlment indexPerforation (oil well)lcsh:Surgerycolorectal cancerAnastomosisGlobalSurg CollaborativeNO03 medical and health sciencesCase mix indexClinical ResearchmedicinecancerHumansanálisis multifactorialDeveloping CountriesAgedemergency abdominal surgery low income surgial care traditional healers cancer mortality outcomes delayElective Surgical Procedurebusiness.industryKirurgiDeveloped Countriesleft colon resection anastomosis end colostomyEvaluation of treatments and therapeutic interventionslcsh:RD1-811Odds ratiomortalitySurgeryProspective StudieLogistic ModelsMultivariate AnalysisSurgeryEmergenciesbusinessDigestive Diseasescolostomíaemergency abdominal surgery
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Plant genetic resources and traditional knowledge on medicinal use of wild shrub and herbaceous plant species in the Etna Regional Park (Eastern Sici…

2014

Ethnopharmacological relevance: This paper illustrates the results of a study carried out in the Etna Regional Park (Eastern Sicily, Italy) concerning the traditional knowledge on medicinal use of wild plant species. It specifies contains the results of a quantitative analysis carried out for the first time. A total of 71 wild species are used for medicinal purposes. Two species, Astracantha sicula (Biv.) Greuter and Trifolium phleoides Willd., are little known as medicinal in the Mediterranean area. Aim of the study: The main aim of the study was to understand to what extent current knowledge on the medicinal use of plants is still an element of the culture within the elderly population of…

Mediterranean climateMaleHealth Knowledge Attitudes Practicecultural erosionved/biology.organism_classification_rank.speciesHealth BehaviorBiodiversitytraditional medicineShrubInterviews as TopicGenetic resourcesDrug DiscoveryHumansTraditional knowledgeSicilybiodiversityAgedPharmacologyAged 80 and overCultural CharacteristicsPlants MedicinalTrifolium phleoidesbusiness.industryved/biologyEcologySettore BIO/02 - Botanica SistematicaAge FactorsEtna Regional ParkHerbaceous plantMiddle Agedquantitative indicesSettore AGR/02 - Agronomia E Coltivazioni ErbaceeGeographyAgricultureSettore BIO/03 - Botanica Ambientale E ApplicataFemaleMedicine TraditionalPlant PreparationsbusinessPhytotherapyJournal of ethnopharmacology
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Herbal medicinal products - Evidence and tradition from a historical perspective.

2017

Abstract Background Aside from the fully licensed herbal medicines there are products on the European pharmaceutical market which are registered by virtue of their longstanding traditional use. The normal registration procedure does not apply to them because presently they do not meet the legal requirements for a full license as set out in the relevant European Union Directive. One of these requirements, “proof of tradition”, has so far been dealt with in different ways and fails to meet the criteria of good practice. Method This analysis is based on a selective literature search in PubMed and in databases of medical and pharmaceutical history, interviews with licensing experts, a consensus…

MedizinLegislation01 natural sciencesHistory 21st Century03 medical and health sciences0302 clinical medicineDrug Discoverymedia_common.cataloged_instanceMedicineHumansddc:610European UnionEuropean unionLicensemedia_commonPharmaceutical industryPharmacologyPlants MedicinalTraditional medicinebusiness.industryHistorical ArticleHistory 20th CenturyDirectiveLegislation Drug0104 chemical sciencesProduct (business)010404 medicinal & biomolecular chemistry030220 oncology & carcinogenesisEngineering ethicsTraditional UseMedicine TraditionalPlant PreparationsbusinessPhytotherapyJournal of ethnopharmacology
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Microbial diversity of traditional Sicilian cheeses

2017

Traditional Sicilian cheeses are manufactured in small size farms with raw milk from animals of indigenous breeds and without the addition of starter cultures. In order to transform milk into cheese, the presence of lactic acid bacteria (LAB) is required. The main sources of desirable LAB are generally the milk, the rennet, the equipment used during processing and the dairy environment. In the last years, the microbial characterisation of traditional Sicilian cheeses, such as Caciocavallo Palermitano, Protected Designation of Origin (PDO) Pecorino Siciliano and PDO Vastedda della valle del Belìce have been the object of different studies conducted by our research group. To this purpose, the…

Microbial diversityMicrobial diversity; traditional Sicilian cheesesSettore AGR/18 - Nutrizione E Alimentazione Animaletraditional Sicilian cheesesSettore AGR/16 - Microbiologia Agraria
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Nutritional profile of Ager cheese selection

2021

Food labels are the main method to ensure that consumers are appropriately informed as regards the food they consume. In Europe, the provision of food information to consumers is regulated by specific laws, including (i) the European Regulation (EU) no 1169/2011, which regulates the mandatory food information including a list of mandatory particulars and nutritional declarations and (ii) the European Regulation (CE) no 1924/2006, concerning the voluntary nutrition and health claims (NHC) made on foods. Nutrient profiling involves the classification and ranking of foods according to their nutritional composition to prevent disease and promote health. For this purpose, the following 14 cheese…

Nutritional profile Traditional cheese Southern Italy
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A Review of the Phytochemistry, Traditional Uses, and Biological Activities of the Genus Ballota and Otostegia

2019

AbstractThe 2 genera Ballota and Otostegia, belonging to the Lamiaceae family, are closely related taxonomically and found mainly in the Mediterranean area, Middle East, and North Africa. Since ancient times, they have been largely employed in traditional medicine for their biological properties such as antimicrobial, anti-inflammatory, antispasmodic, insecticidal, anti-malaria, etc. Phytochemical investigations of Ballota and Otostegia species have revealed that diterpenoids are the main constituents of the genera. A large number of flavonoids and other metabolites were also identified. This review, covering literature from 1911 up to 2018, includes traditional uses, chemical profiles (bot…

OtostegiaantioxidantPhytochemistryfood.ingredientPharmaceutical Sciencesecondary metabolite01 natural sciencesAnalytical ChemistryfoodGenusBiological propertyDrug DiscoveryAnimalsHumansSettore BIO/15 - Biologia FarmaceuticaPharmacologyLamiaceaebiologyTraditional medicinePlant Extracts010405 organic chemistryOrganic ChemistrySettore CHIM/06 - Chimica OrganicaBallotabiology.organism_classification0104 chemical sciencesantibacterial010404 medicinal & biomolecular chemistryTaxonComplementary and alternative medicinePhytochemicalMolecular MedicineLamiaceaeMedicine TraditionalOtostegiaBallotaantifungalPhytotherapyPlanta Medica
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Traditional Chinese herbal medicine at the forefront battle against COVID-19: Clinical experience and scientific basis.

2020

Abstract Background Throughout the 5000-year history of China, more than 300 epidemics were recorded. Traditional Chinese herbal medicine (TCM) has been used effectively to combat each of these epidemics’ infections, and saved many lives. To date, there are hundreds of herbal TCM formulae developed for the purpose of prevention and treatment during epidemic infections. When COVID-19 ravaged the Wuhan district in China in early January 2020, without a deep understanding about the nature of COVID-19, patients admitted to the TCM Hospital in Wuhan were immediately treated with TCM and reported later with >90% efficacy. Approach We conducted conduct a systematic survey of various TCM herbal pre…

PTGS2 Prostaglandin-endoperoxide synthase 2BattleAIV avian influenza virusCoV coronavirusPharmaceutical ScienceiNOS nitric oxide synthaseViral infection0302 clinical medicinePA patchouli alcoholSARS Severe Acute Respiratory SyndromeSMD Sheganmahuang decoctionDrug DiscoveryPandemicIL InterleukinMedicine Chinese TraditionalALI acute lung injuriesmedia_commonCOVID-19 coronavirus disease 2019MXSG Ma xing shi gan decoction0303 health sciencesTNF tumor necrosis factorClinical Trials as TopicCCL2 CC chemokine ligand 2FM1 FM1 coronavirusICU intensive care unitc-AMP cyclic adenosine phosphateHIV human immunodeficiency virus030220 oncology & carcinogenesisCOX-2 cyclooxygenase-2Molecular MedicineHerbal preparationsMedicinal herbsAbbreviations: ACE2 angiotensin-converting enzyme IITCM traditional Chinese medicineHSV-1 herpes simplex virus 1CASP3 caspase 3medicine.medical_specialtyChinaCoronavirus disease 2019 (COVID-19)Systematic surveymedia_common.quotation_subjectJEV Japanese encephalitis virusNF-κB nuclear factor kappa B cellsAntiviral AgentsArticleWHO World Health Organization03 medical and health sciencesIEC-6 rat intestinal epithelial cell line 6SOD superoxide dismutaseCDC Center for Disease Control and PreventionmedicineAVP arginine vasopressinPGE2 prostaglandin E2HumansIntensive care medicineLH Lianhuaqingwen capsule030304 developmental biologyPharmacologyMedicinal herbMDA malondialdehydeGCGJ Gancao ganjiang decoctionNO nitric oxidePlants Medicinalbusiness.industrySARS-CoV-2COVID-19CXCL C-X-C- motif chemokineMDCK Madin-Darby Canine Kidney cellsTLR-4 Toll-like receptor-4COVID-19 Drug TreatmentComplementary and alternative medicineViral infectionLPS lipopolysaccharidesRSV respiratory syncytial virusQFPD Qingfeipaidu decoctionbusinessLung congestionECMO extracorporeal membrane oxygenationMAPK mitogen-activated protein kinasePhytotherapyDrugs Chinese HerbalPhytomedicine : international journal of phytotherapy and phytopharmacology
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