Search results for " Transferrin"

showing 4 items of 34 documents

Regulation of the Transferrin Receptor Recycling in Hepatitis C Virus-Replicating Cells

2020

After binding of its ligand transferrin, the transferrin receptor (TfR) is internalized via early endosomes. Ligand and receptor can be recycled. α-Taxilin was identified as an essential factor for TfR recycling. Apart from its role for iron uptake, TfR is a coreceptor for hepatitis C virus (HCV) infection. In HCV-replicating cells, the amount of a-taxilin is decreased. This study aims to investigate the effect of decreased α-taxilin levels in HCV-replicating cells on recycling of TfR, its amount on the cell surface, on iron uptake, and the impact of a disturbed TfR recycling on HCV superinfection exclusion. TfR amount and localization were determined by CLSM and surface biotinylation. α-ta…

hepatitis C virus0301 basic medicineEndosomemedia_common.quotation_subjectTransferrin receptorSuperinfection exclusionCell and Developmental Biology03 medical and health sciences0302 clinical medicineiron metabolismInternalizationReceptorlcsh:QH301-705.5iron metabolism ; transferrin receptor ; α-taxilin ; HCV superinfection ; Hepatitis C ; hepatitis C virusOriginal Researchmedia_commonchemistry.chemical_classificationα-taxilinHCV superinfectionvirus diseasesCell Biologytransferrin receptorLigand (biochemistry)Cell biology030104 developmental biologylcsh:Biology (General)chemistryTransferrin030220 oncology & carcinogenesisIntracellularDevelopmental BiologyFrontiers in Cell and Developmental Biology
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Fluorescent quantum dot labeling of canine transferrin receptor with biotin ligase

2007

koiran parvoviruscanine transferrin receptorcanine parvovirusquantum dotbiotin ligaseparvoviruksetBirA
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Experimental analysis, numerical and analytical modeling of shear strength mechanisms in Hybrid Steel Trussed Concrete Beams

2014

stress transferring mechanismhybrid steel trussed-concrete beams; push-out tests; shear connection; stress transferring mechanism; three-point bending tests; shear resistance; size effect; finite element modeling; analytical modelingmodellazione analiticathree-point bending testsfinite element modelinghybrid steel trussed-concrete beamsprove sperimentaliresistenza a taglioanalytical modelingtravi tralicciate misteshear resistanceSettore ICAR/09 - Tecnica Delle Costruzioniexperimental testsize effectpush-out testsmodellazione numericashear connectionshear strengthhybrid steel-trussed concrete beam
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Testing and Modeling of Hybrid Steel-Trussed Concrete Beams in Shear

2014

three-point bending teststress transferring mechanismhybrid steel trussed-concrete beams; push-out tests; shear connection; stress transferring mechanism; three-point bending tests; shear resistance; size effect; finite element modeling; analytical modelingthree-point bending testsfinite element modelinghybrid steel trussed-concrete beamspush-out testanalytical modelingshear resistancehybrid steel trussed-concrete beamSettore ICAR/09 - Tecnica Delle Costruzionisize effectpush-out testsshear connection
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