Search results for " Transformation"

Contact-dependent inhibition of growth of normal diploid human fibroblasts by plasma membrane glycoproteins.

1988

Homeostasis in vivo is maintained by a highly complex network of positive and negative signals. At the cellular level, this regulatory microenvironment can be divided, in a simplified fashion, into two major compartments: the humoral compartment, including compounds such as hormones, growth factors and nutrients, and the contact-environment compartment, including cell-cell and cell-matrix interactions. At least in cultures of diploid, non-transformed cells, cell-cell and cell-matrix interactions have been shown to be of major importance for the regulation of growth as well as of differentiation. Although until now the glycoprotein involved in the contact-dependent inhibition of growth has n…

Innovative and Sustainable Food Business Models

2019

Companies are called upon to solve the great challenges of the new millennium. The food sector, from this point of view, plays a strategic role. Poverty, malnutrition, hunger, climate change, and social inequalities are just some of the trends which the agri-food sector has to cope with. The digital transformation that companies will need to embrace to survive requires new ways of creating, thinking, and working with technology-driven tools to provide value for their businesses and customers. Digitization, whether it pertains to new technologies, the analysis of big data or the development of on-line and spatial applications, can contribute to achieving systemic food production transformati…

Transformation of UML models to CSP : a case study for graph transformation tools

2008

Graph transformation provides an intuitive mechanism for capturing model transformations. In the current paper, we investigate and compare various graph transformation tools using a compact practical model transformation case study carried out as part of the AGTIVE 2007 Tool Contest [22]. The aim of this case study is to generate formal CSP processes from high-level UML activity diagrams, which enables to carry out mathematical analysis of the system under design.

A survey and comparison of transformation tools based on the transformation tool contest

2014

Model transformation is one of the key tasks in model-driven engineering and relies on the efficient matching and modification of graph-based data structures; its sibling graph rewriting has been used to successfully model problems in a variety of domains. Over the last years, a wide range of graph and model transformation tools have been developed – all of them with their own particular strengths and typical application domains. In this paper, we give a survey and a comparison of the model and graph transformation tools that participated at the Transformation Tool Contest 2011. The reader gains an overview of the field and its tools, based on the illustrative solutions submitted to a Hello…

Einstein’s gravitational field equations and the bianchi identities

2002

In his highly acclaimed biography of Einstein, Abraham Pais gave a fairly detailed analysis of the many difficulties his hero had to overcome in November 1915 before he finally arrived at generally covariant equations for gravitation (Pais 1982, 250–261).

Metal- and Reagent-Free Dehydrogenative Formal Benzyl-Aryl Cross-Coupling by Anodic Activation in 1,1,1,3,3,3-Hexafluoropropan-2-ol

2018

A selective dehydrogenative electrochemical functionalization of benzylic positions that employs 1,1,1,3,3,3-hexafluoropropan-2-ol (HFIP) has been developed. The electrogenerated products are versatile intermediates for subsequent functionalizations as they act as masked benzylic cations that can be easily activated. Herein, we report a sustainable, scalable, and reagent- and metal-free dehydrogenative formal benzyl-aryl cross-coupling. Liberation of the benzylic cation was accomplished through the use of acid. Valuable diarylmethanes are accessible in the presence of aromatic nucleophiles. The direct application of electricity enables a safe and environmentally benign chemical transformati…

A hybrid framework of multiple active appearance models and global registration for 3D prostate segmentation in MRI.

2012

International audience; Real-time fusion of Magnetic Resonance (MR) and Trans Rectal Ultra Sound (TRUS) images aid in the localization of malignant tissues in TRUS guided prostate biopsy. Registration performed on segmented contours of the prostate reduces computational complexity and improves the multimodal registration accuracy. However, accurate and computationally efficient 3D segmentation of the prostate in MR images could be a challenging task due to inter-patient shape and intensity variability of the prostate gland. In this work, we propose to use multiple statistical shape and appearance models to segment the prostate in 2D and a global registration framework to impose shape restri…

Datorzinātne un informācijas tehnoloģijas

2011

Human papillomaviruses in oral carcinoma and oral potentially malignant disorders: a systematic review.

2011

Human papillomavirus (HPV) in oral carcinoma (OSCC) and potentially malignant disorders (OPMD) is controversial. The primary aim was to calculate pooled risk estimates for the association of HPV with OSCC and OPMD when compared with healthy oral mucosa as controls. We also examined the effects of sampling techniques on HPV detection rates. Methods: Systematic review was performed using PubMed (January 1966-September 2010) and EMBASE (January 1990-September 2010). Eligible studies included randomized controlled, cohort and cross-sectional studies. Pooled data were analysed by calculating odds ratios, using a random effects model. Risk of bias was based on characteristics of study group, appr…

Analytic energy gradients for the spin-free exact two-component theory using an exact block diagonalization for the one-electron Dirac Hamiltonian.

2011

We report the implementation of analytic energy gradients for the evaluation of first-order electrical properties and nuclear forces within the framework of the spin-free (SF) exact two-component (X2c) theory. In the scheme presented here, referred to in the following as SFX2c-1e, the decoupling of electronic and positronic solutions is performed for the one-electron Dirac Hamiltonian in its matrix representation using a single unitary transformation. The resulting two-component one-electron matrix Hamiltonian is combined with untransformed two-electron interactions for subsequent self-consistent-field and electron-correlated calculations. The "picture-change" effect in the calculation of p…