Search results for " Transformation"

Martensitic phase transformation cubic-orthorhombic of NaCN and (NaCN)0.98 (KCN)0.02

1990

The ferroelastic cubic-orthorhombic transition of single crystals NaCN and (NaCN)0.98 (KCN)0.02 has been studied by x-ray diffraction. The domain configuration obtained is consistent with the Wechsler, Lieberman, Read-model for martensitic transformations.

Loss of Hyperconjugative Effects Drives Hydride Transfer during Dihydrofolate Reductase Catalysis

2019

Hydride transfer is widespread in nature and has an essential role in applied research. However, the mechanisms of how this transformation occurs in living organisms remain a matter of vigorous debate. Here, we examined dihydrofolate reductase (DHFR), an enzyme that catalyzes hydride from C4′ of NADPH to C6 of 7,8-dihydrofolate (H2F). Despite many investigations of the mechanism of this reaction, the contribution of polarization of the π-bond of H2F in driving hydride transfer remains unclear. H2F was stereospecifically labeled with deuterium β to the reacting center, and β-deuterium kinetic isotope effects were measured. Our experimental results combined with analysis derived from QM/MM si…

VI JORNADAS ARTE Y CIUDAD (III Encuentros Internacionales) Madrid, 1, 2 y 3 de Abril de 2014 Facultad de Ciencias de la Información Universidad Compl…

2014

In the conquest of Valencia in 1238 and its subsequent Christianization we find the genesis of the convent city. Over the centuries the dominant presence of convents and monasteries determined various aspects of the city, urban development being one of them. However, the influence and power that these monasteries exercised diminished gradually with the reduction in the number of their members and foundations. The point of no return comes with the nineteenth century when the successive confiscations and the consolidation of the bourgeoisie mean its fading. This study aims to make an approach to the role that the destruction of convents and monasteries played in the urban development and prog…

Living in future cities: from overbuilding to ecological transition

2022

In contemporary cities the levels of livability and urban quality are less and less optimal. There are various causes: climate and demographic changes, reduction of natural resources, health risks, excessive consumption of soil, increased pollution, impoverishment of populations, lack of employment, transformation of urban space, etc. Evolving cities, increasingly vulnerable, characterized by insecurity, uncertainty and unpredictability, the result of mistakes made in the past. In this context, in planning future scenarios it is necessary to re-examine the governance, the strategies of urban expansion and transformation through new approaches capable of declining innovative concepts such as…

What is (not) the point of just transition in food systems?

2022

Food systems are confronted with a low-carbon transition challenge. The need for significant emission reductions in industrial food systems implies significant systemic transformations in food production, processing, and consumption. The wide-reaching impacts of such transformations have evoked public discussion and academic research on just transition in food systems. The undisputable legitimacy of the idea of just transition makes it an attractive concept for all food system actors who might be affected by low-carbon transition policies in direct and indirect ways. Some of the claims that are being made are warranted claims for justice, some merely defend the achieved privileges and benef…

Solubility-Driven Isolation of a Metastable Nonagold Cluster with Body-Centered Cubic Structure.

2020

The conventional synthetic methodology of atomically precise gold nanoclusters using reduction in solutions offers only thermodynamically most stable nanoclusters. We report herein a solubility‐driven isolation strategy to access the synthesis of a metastable gold cluster. The cluster, with the composition of [Au 9 (PPh 3 ) 8 ] + ( 1 ), displays an unusual, nearly perfect body‐centered‐cubic (bcc) structure. As revealed by ESI‐MS and UV/Vis measurement, the cluster is metastable in solution and converts to the well‐known [Au 11 (PPh 3 ) 8 Cl 2 ] + ( 2 ) within just 90 min. DFT calculations revealed that while both 1 and 2 are eight‐electron superatoms, there is a driving force to convert 1 …

Bleomycin: Action on growth of oncogenic RNA viruses and on cell transformation

1975

Bleomycin (BLM) inhibits cell proliferation of noninfected chick embryo fibroblasts by blocking their DNA synthesis selectively. Chick embryo fibroblasts have beentransformed by Schmidt-Ruppin D strain of Rous Sarcoma Virus. Transformation has been determined by a focus assay. Foci formation is strongly reduced by BLM. Virus replication is inhibited by BLM in growing and confluent monolayer cells. This result might be explained by the observation that this drug reduces proliferation of growing and of confluent monolayer cells very sensitively. During the first 24 hours after infection the BLM inhibitory effect is more pronounced than in the case of BLM-application during the period 24--48 h…

Une souveraineté post-nationale ?

2009

Exploratory remarks and discussion on a potential program for interlock even more the mathematics and physics

2021

These remarks are endowed with exploratory argumentation for disrupt further discussion and in favor of the in-depth consolidation of a mathematical and physics identification based on 2 key concepts: 1) finite support and 2) a notion of infinite intrinsic to the usage of the complex numbers. General relativity shows up linked to a kind of a Gelfand representation as an approximation of an analog of a hidden Markov Model. This has deep connections with the Stone–Weierstrass theorem and these discussion are an invitation to the physics community to study the physics x mathematics identification in the case of a holding true multiverse hypothesis. Photon in this setup stands to the analog of …

Relevance and Role of Contemporary Architecture Preservation—Assessing and Evaluating Architectural Heritage as a Contemporary Landscape: A Study Cas…

2023

Since WWII to the 2000s, numerous masters of contemporary architecture have contributed to the construction of new landscapes with their works; therefore, these places have become part of a changing landscape and of the multifaceted process of landscape generation. Nevertheless, during this fifty-year period, capitalism has led to the destruction of many existing landscapes, and the policies of protection and preservation have often entailed a process of musealization. In 2000, the European Landscape Convention adopted a new common-grounded definition of landscape, integrating a wide set of cultural approaches and disciplinary topics. Starting from the assumption that contemporary architect…