Search results for " Transport"

PASSENGER NAME RECORD (PNR)

2018

Lo scritto prende in esame la questione relativa al trattamento e al trasferimento dei dati personali dei passeggeri (PNR) nel trasporto aereo, con lo scopo di combattere il terrorismo internazionale e la criminalità transnazionale. La questione è stata molto dibattuta a livello europeo, a partire dal primo accordo tra USA-Ue nel 2004, poi abrogato dalla Corte di giustizia Ue, sino ai tempi più recenti, con l’approvazione della direttiva 681/2016 e il parere 1/15 del 2017 della Corte di giustizia sulla compatibilità tra l’accordo Ue-Canada e il vigente quadro normativo dell’Ue, successivo all’entrata in vigore del trattato di Lisbona e della Carta dei diritti fondamentali dell’Unione europe…

Is ATP Hydrolysis the Power Stroke in ABC Transporters?

2018

The Non-neuronal Cholinergic System

2001

An increasing body of knowledge indicates that the cholinergic system is not confined to the nervous system, but is practically ubiquitous. The present paper will address the question of the non-neuronal cholinergic system in vascular endothelial cells (EC). In tissue sections of human skin, immunohistochemical studies using confocal laser scanning microscopy showed ChAT (choline acetyltransferase) activity in the EC of dermal blood vessels. Positive ChAT immunoreactivity was also demonstrated in monolayer cultures of human umbilical vein EC (HUVEC) and a human angiosarcoma EC line (HAEND). That the synthesizing enzyme is not only present in EC, but also active was shown by measuring ChAT a…

COMMUTING PATTERNS IN RIGA AGGLOMERATION: EVIDENCE FROM A SURVEY ANALYSIS OF YOUTH

2021

In the last ten years the evident changes of settlement patterns through suburban growth near to capital city of Latvia occurred. Increase of distance between home and routine activity places as well as changes of public transport and rapid increase of car ownership initiated significant changes in commuting patterns of inhabitants living outside of Riga. Although the commuting from suburban area to Riga is recently broadly studied, however these researches focused primarily on able-bodied population leaving behind school-age children and young people. The aim of this study is to analyse commuting patterns of young people aged 12 to 17 moving from outskirts of Riga to school located in Riga…

Implementation of a bicycle-sharing program: An effective way of introducing cycling as mode of transport

2012

Generation of a proton potential by succinate dehydrogenase of Bacillus subtilis functioning as a fumarate reductase

2001

The membrane fraction of Bacillus subtilis catalyzes the reduction of fumarate to succinate by NADH. The activity is inhibited by low concentrations of 2-(heptyl)-4-hydroxyquinoline-N-oxide (HOQNO), an inhibitor of succinate: quinone reductase. In sdh or aro mutant strains, which lack succinate dehydrogenase or menaquinone, respectively, the activity of fumarate reduction by NADH was missing. In resting cells fumarate reduction required glycerol or glucose as the electron donor, which presumably supply NADH for fumarate reduction. Thus in the bacteria, fumarate reduction by NADH is catalyzed by an electron transport chain consisting of NADH dehydrogenase (NADH:menaquinone reductase), menaqu…

Quantum transport of single neutral atoms

2007

The state-selective (quantum) transport of single neutral atoms stored in a one dimensional optical lattice is a promising technique to implement controlled atomic interaction using coherent cold collisions. This is required in several schemes of quantum information processing. Here, we present a technical implementation of the quantum transport scheme for one, two and more caesium atoms, as well as the manipulation and detection of their internal states.

Enhanced tonic GABAA inhibition in typical absence epilepsy

2009

The cellular mechanisms underlying typical absence seizures, which characterize various idiopathic generalized epilepsies, are not fully understood, but impaired γ-aminobutyric acid (GABA)-ergic inhibition remains an attractive hypothesis. In contrast, we show here that extrasynaptic GABAA receptor–dependent 'tonic' inhibition is increased in thalamocortical neurons from diverse genetic and pharmacological models of absence seizures. Increased tonic inhibition is due to compromised GABA uptake by the GABA transporter GAT-1 in the genetic models tested, and GAT-1 is crucial in governing seizure genesis. Extrasynaptic GABAA receptors are a requirement for seizures in two of the best character…

Using Genetic Algorithms for Optimizing the PPC in the Highway Horizontal Alignment Design.

2016

Various studies have emphasized the interesting advantages related to the use of new transition curves for improving the geometric design of highway horizontal alignments. In a previous paper, one of the writers proposed a polynomial curve, called a polynomial parametric curve (PPC), proving its efficiency in solving several design problems characterized by a very complex geometry (egg-shaped transition, transition between reversing circular curves, semidirect and inner-loop connections, and so on). The PPC also showed considerable advantages from a dynamic perspective, as evidenced by the analysis of the main dynamic variables related to motion (as well as rate of change of radial accelera…

Synthesis and evaluation of (S)-2-(2-[18F]fluoroethoxy)-4-([3-methyl-1-(2-piperidin-1-yl-phenyl)-butyl-carbamoyl]-methyl)-benzoic acid ([18F]repaglin…

2004

18F-labeled non-sulfonylurea hypoglycemic agent (S)-2-(2-[(18)F]fluoroethoxy)-4-((3-methyl-1-(2-piperidin-1-yl-phenyl)-butylcarbamoyl)-methyl)-benzoic acid ([(18)F]repaglinide), a derivative of the sulfonylurea-receptor (SUR) ligand repaglinide, was synthesized as a potential tracer for the non-invasive investigation of the sulfonylurea 1 receptor status of pancreatic beta-cells by positron emission tomography (PET) in the context of type 1 and type 2 diabetes. [(18)F]Repaglinide could be obtained in an overall radiochemical yield (RCY) of 20% after 135 min with a radiochemical purity higher than 98% applying the secondary labeling precursor 2-[(18)F]fluoroethyltosylate. Specific activity w…