Search results for " United States"

showing 9 items of 49 documents

New techs, new threats: sfide e opportunità della rivoluzione blockchain

2021

Considering the current diffusion of blockchain technology in the most different fields, ranging from public governance to economics, from contractual applications to health, the contribution addresses the issue of the legal regulation of this new technology, precisely because of its vast applications. From the comparison between the European model and the American one, the approach of the European legislator ‒ despite the delay with which the institutions have addressed the issue, seems to show, as already happened in other areas, a more 'social oriented' perspective and based on a sort of 'democratization' of data compared to the American approach, more ‘business oriented’, where the scho…

blockchain European Union United States regulatory sandbox methodSettore IUS/01 - Diritto PrivatoSettore IUS/02 - Diritto Privato Comparato
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The new world of human genetic technologies: The policy environment and impacts of genetic screening tests

1995

Today it is possible to screen for mutated DNA sequences which do not induce any diseases but predispose to develop diseases under certain environmental condition. These latter disorders are called “multifactorial” since they result from the interplay of genetic and environmental factors. Among multifactorial disorders there are job-related diseases whose genetic component can be identified by genetic screening tests. The use of these tests to predict occupational disorders, to cut down on them, and to save costs—in particular for absenteeism, health care, and lawsuits—is of interest to employers and insurers. As for employees, it could entail an extremely deep invasion of privacy, economic…

business.industryGenetic counselingGenetic disorderPrivacy laws of the United StatesDiseasemedicine.diseaseHuman-Computer InteractionPhilosophyRisk analysis (engineering)Artificial IntelligenceHealth caremedicineAbsenteeismGenetic predispositionBusinessEconomic problemAI & Society
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Hablantes de herencia del español en Estados Unidos: implicaciones para el entrenamiento de instructores en el nivel universitario

2013

Este estudio investiga las necesidades pedagógicas de los estudiantes de español como lengua de herencia (LH) en el nivel universitario. Basado en un análisis del perfil del hablante de herencia del español en el contexto de Estados Unidos y en un estudio del Departamento de Lenguas y Literaturas Modernas de la Universidad de Nebraska-Lincoln como caso ilustrativo, esta investigación busca explorar argumentos que apoyen la necesidad de proporcionar un entrenamiento a instructores de español del nivel universitario que responda a las necesidades pedagógicas específicas de los hablantes de herencia. This study researches the pedagogical needs of learners of Spanish as a Heritage Language (HL)…

caso ilustrativoEstados Unidos Heritage speakers of Spanishillustrative caseuniversity teacher trainingentrenamiento pedagógico universitario:SOCIOLOGÍA::Cambio y desarrollo social [UNESCO]UNESCO::SOCIOLOGÍA::Cambio y desarrollo socialhablantes de español como lengua de herenciaUnited States Artículohablantes de español como lengua de herencia ; entrenamiento pedagógico universitario ; caso ilustrativo ; Estados Unidos Heritage speakers of Spanish ; university teacher training ; illustrative case ; United States Artículo
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Comparing the Climatic and Landscape Risk Factors for Lyme Disease Cases in the Upper Midwest and Northeast United States

2020

Lyme disease, recognized as one of the most important vector-borne diseases worldwide, has been increasing in incidence and spatial extend in United States. In the Northeast and Upper Midwest, Lyme disease is transmitted by Ixodes scapularis. Currently, many studies have been conducted to identify factors influencing Lyme disease risk in the Northeast, however, relatively few studies focused on the Upper Midwest. In this study, we explored and compared the climatic and landscape factors that shape the spatial patterns of human Lyme cases in these two regions, using the generalized linear mixed models. Our results showed that climatic variables generally had opposite correlations with Lyme d…

esiintyvyysympäristötekijätHealth Toxicology and MutagenesisClimate030231 tropical medicinelcsh:MedicineEnvironmentForestsmaisemaArticleMidwestern United Statesmetsätyypit03 medical and health sciences0302 clinical medicineLyme diseaseNew EnglandRisk FactorsLymen borrelioosimedicineLyme diseaseAnimalsHumans030212 general & internal medicineBorrelia burgdorfericlimateforest fragmentationLyme DiseasebiologyIxodespaikallisilmastoIncidence (epidemiology)lcsh:RPublic Health Environmental and Occupational HealthClimatic variablesmedicine.diseasebiology.organism_classificationbacterial infections and mycosesLYMEBorrelia-bakteerit<i>Borrelia burgdorferi</i>DeciduousGeographyborrelioosiIxodes scapularisBorrelia burgdorferiSpatial ecologyLinear ModelsDemographyInternational Journal of Environmental Research and Public Health
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USA on the road: da The Americans di Robert Frank ad American Surfaces di Stephen Shore

2018

Robert Frank’s and Stephen Shore’s photographic reportages and their travels document an identity of the United States different from the conventional representations that usually show a successful country, able to enforce its social, economic, political, and aesthetics models. These reportages represent an other America, far from the stereotypes and full of contradictions: the places of common experience (almost non-places), the characters disillusioned and frustrated by the American dream, the banality of the situations represented, the commonplace, show that besides a winner’s imagery (like, recently, the one represented by Trump but also by Pete Souza, official photographer of Barack Ob…

lcsh:American literatureunited statesrobert frankaestheticsreportageSettore M-FIL/04 - Esteticalcsh:PR1-9680stephen shorephotographyestetica fotografia cultura visuale Robert Frank Stephen ShoreRobert Frank; Stephen Shore; United States; photography; aesthetics; reportagelcsh:PS1-3576lcsh:English literature
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Immunoaffinity purification and characterization of mitochondrial membrane-bound D-3-hydroxybutyrate dehydrogenase from Jaculus orientalis.

2008

Abstract Background The interconversion of two important energy metabolites, 3-hydroxybutyrate and acetoacetate (the major ketone bodies), is catalyzed by D-3-hydroxybutyrate dehydrogenase (BDH1: EC 1.1.1.30), a NAD+-dependent enzyme. The eukaryotic enzyme is bound to the mitochondrial inner membrane and harbors a unique lecithin-dependent activity. Here, we report an advanced purification method of the mammalian BDH applied to the liver enzyme from jerboa (Jaculus orientalis), a hibernating rodent adapted to extreme diet and environmental conditions. Results Purifying BDH from jerboa liver overcomes its low specific activity in mitochondria for further biochemical characterization of the e…

lcsh:Animal biochemistryMESH : AgedMESH : RodentiaMESH: RodentiaMESH: Base SequenceBiochemistryMESH: Lipid PeroxidationMESH : Information ServicesAntigen-Antibody ReactionsMESH: Health EducationEpitopesMESH: OrganizationsMESH: LibrariesMESH: Antigen-Antibody Reactionslcsh:QD415-436MESH: AnimalsMESH : OrganizationsMESH : Physician's RoleMESH: Bacterial ProteinsImmunosorbent Techniqueschemistry.chemical_classificationMESH: Conserved SequenceMethodology ArticleMESH : Computer Communication NetworksMESH: Chromatography AffinityMESH : Pseudomonas aeruginosaMESH : Chromatography AffinityMESH : Immunosorbent TechniquesMESH: Ethnic GroupsMESH : Ethnic GroupsMESH: EpitopesMESH : Patient SatisfactionMESH : United StatesMESH: MitochondriaMESH : Antigen-Antibody ReactionsMolecular Sequence DataMESH : Hydroxybutyrate DehydrogenaseMESH: Sequence AlignmentRodentiaMESH: Information ServicesMESH : Epitopeslcsh:BiochemistryMESH : Mitochondrial MembranesBacterial ProteinsMESH : Conserved SequenceComplementary DNAMESH : LibrariesMolecular Biology[ SDV.BBM ] Life Sciences [q-bio]/Biochemistry Molecular BiologyMESH: Immunosorbent TechniquesMESH: Molecular Sequence DataMESH: HumansMESH : Consumer ParticipationMESH : HumansMESH: AdultMESH: Patient SatisfactionMESH: Hydroxybutyrate DehydrogenaseMESH: Consumer ParticipationchemistryLipid PeroxidationMESH: FemaleMESH: LiverMESH : Sequence Analysis DNAMESH: Continental Population GroupsMESH: Sequence Analysis DNAMESH : Molecular Sequence DataDehydrogenaseChromatography AffinityMESH: Mitochondrial MembranesMESH: Antibodies BacterialMESH : Bacterial ProteinsMESH : FemaleMESH: Computer Communication NetworksConserved SequenceMESH: AgedbiologyMESH : Lipid PeroxidationMESH : Sequence AlignmentMESH: Physician's RoleMESH : AdultAntibodies BacterialMitochondriaAmino acidLiverBiochemistryMitochondrial MembranesPseudomonas aeruginosaMESH: Pseudomonas aeruginosaMESH : MitochondriaMESH : Mass MediaMESH: Mass MediaMESH : MaleHydroxybutyrate DehydrogenaseAffinity chromatographyMESH : Health Education[SDV.BBM] Life Sciences [q-bio]/Biochemistry Molecular BiologyMESH: United StatesAnimals[SDV.BBM]Life Sciences [q-bio]/Biochemistry Molecular BiologyMESH : Antibodies Bacteriallcsh:QP501-801Jaculus orientalisMESH : Continental Population GroupsBase SequenceMESH : LiverSequence Analysis DNAbiology.organism_classificationMolecular biologyMESH: MaleEnzymePolyclonal antibodiesbiology.proteinMESH : Base SequenceNAD+ kinaseMESH : AnimalsSequence Alignment
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Monoclonal antibodies for the treatment of non-haematological tumours: update of an expanding scenario.

2015

Abstract: Introduction: The identification of cell membrane-bound molecules with a relevant role in cancer cell survival prompted the development of moAbs to block the related pathways. In the last few years, the number of approved moAbs for cancer treatment has constantly increased. Many of these drugs significantly improved the survival outcomes in patients with solid tumours. Areas covered: In this review, all the FDA-approved moAbs in solid tumours have been described. This is an update of moAbs available for cancer treatment nowadays in comparison with the moAbs approved until few years ago. The moAbs under development are also discussed here. Expert opinion: The research on cancer ant…

medicine.medical_treatmentClinical BiochemistryCellReceptor activator of nuclear factor κB ligandCancer; Cancer antigen; Cytotoxic T-lymphocyte antigen 4; EGFR; HER2; Immunotherapy; MoAbs; Receptor activator of nuclear factor κB ligand; VEGF; Antibodies Monoclonal; Drug Approval; Drug Discovery; Humans; Immunotherapy; Neoplasms; United States; United States Food and Drug Administration; Pharmacology; Clinical Biochemistry; Drug Discovery3003 Pharmaceutical Science; Medicine (all)NeoplasmsMonoclonalDrug DiscoveryDrug approvalCancer; Cancer antigen; Cytotoxic T-lymphocyte antigen 4; EGFR; HER2; Immunotherapy; MoAbs; Receptor activator of nuclear factor κB ligand; VEGF; Antibodies; Monoclonal; Drug Approval; Drug Discovery; Humans; Immunotherapy; Neoplasms; United States; United States Food and Drug Administration; Pharmacology; Clinical Biochemistry; Drug Discovery3003 Pharmaceutical Science; Medicine (all); Cancer; Cancer antigen; Cytotoxic T-lymphocyte antigen 4; EGFR; HER2; Immunotherapy; MoAbs; Receptor activator of nuclear factor κB ligand; VEGF; Antibodies; Monoclonal; Drug Approval; Drug Discovery; Humans; Immunotherapy; Neoplasms; United States; United States Food and Drug Administration; Pharmacology; Clinical Biochemistry; Drug Discovery3003 Pharmaceutical Science; Medicine (all)Drug ApprovalCancerbiologyMedicine (all)Antibodies MonoclonalVEGFReceptor activator of nuclear factor κB ligandmedicine.anatomical_structureMonoclonalMoAbsImmunotherapyAntibodyEngineering sciences. TechnologyHumanUnited StateCancer; Cancer antigen; Cytotoxic T-lymphocyte antigen 4; EGFR; HER2; Immunotherapy; MoAbs; Receptor activator of nuclear factor κB ligand; VEGF; Antibodies Monoclonal; Drug Approval; Drug Discovery; Humans; Immunotherapy; Neoplasms; United States; United States Food and Drug Administration; Pharmacology; Clinical Biochemistry; Drug Discovery3003 Pharmaceutical Science; Medicine (all)medicine.drug_classEGFRMonoclonal antibodyAntibodiesCancer antigenCytotoxic T-lymphocyte antigen 4HER2medicineHumansBiologyPharmacologybusiness.industryUnited States Food and Drug AdministrationDrug Discovery3003 Pharmaceutical ScienceCancerImmunotherapymedicine.diseaseUnited StatesImmunologyCancer cellCancer researchbiology.proteinNeoplasmMoAbHuman medicinebusinessExpert opinion on biological therapy
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Federaliści i rozłam między klasycznością a modernością

2014

The article shows how the classical political thinking, based on civic virtues, and modernist thinking, based on individualism and self-interest, formed the basis of the U.S. Constitution. The Founding Fathers did not realize the full extent of the rift between classicism and modernity. When, as a result of intellectual discussions and practice of social life, this divide began to become more and more obvious, there has been a transition from the classical to the modernist paradigm in American politics. However, the dispute between classicism and modernity still continues and takes on new forms. On the one hand, contemporary political thinking is seen as a triumph of modernism, in which the…

post-modernityThomas JeffersonJohn LockedifferenceFederalistsAlexander HamiltonMartin Heideggerfounding fathers of the United StatesindividualismJohn AdamsThomas HobbesWestern civilizationdeconstructionJames Madisonclassical traditionmodernityvirtueRuch Filozoficzny
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Towards CCTV-aware Routing and Navigation for Privacy, Anonymity, and Safety - Feasibility Study in Jyväskylä

2021

AbstractIn order to withstand the ever-increasing invasion of privacy by CCTV cameras and technologies, on par CCTV-aware solutions must exist that provide privacy, safety, and cybersecurity features. We argue that a first important step towards such CCTV-aware solutions must be a mapping system (e.g., Google Maps, OpenStreetMap) that provides both privacy and safety routing and navigation options. Unfortunately, to the best of our knowledge, there are no mapping nor navigation systems that support CCTV-privacy and CCTV-safety routing options. At the same time, in order to move the privacy vs. safety debate related to CCTV surveillance cameras from purely subjective to data-driven and evide…

safetyComputer sciencePrivacy laws of the United StatesContext (language use)PedestrianprivacyComputer securitycomputer.software_genrelcsh:TelecommunicationDomain (software engineering)anti-surveillancelcsh:TK5101-6720yksityisyyskameravalvontakarttapalvelutcctv-aware technologymappingnavigationreititysanonymityNavigation systemvalvontajärjestelmätcctvroutingsurveillanceRouting (electronic design automation)anonymiteettiScale (map)yksilönsuojacomputerAnonymity2021 28th Conference of Open Innovations Association (FRUCT)
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