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La Biblioteca dell'Università

2022

Il tema di progetto della Biblioteca costituisce l’occasione suggestiva per ripensare la città e ragionare sul valore dello spazio pubblico. Da “luogo dei libri”, la Biblioteca è oggi divenuta contenitore flessibile per molteplici funzioni, dispositivo di dialogo e relazioni a servizio dell’idea di cittadinanza e della bellezza. In modo particolare la Biblioteca dell’Università - oltre ad essere luogo di comunicazione, spazio di socializzazione, centro di informazione - per il significato e il suo valore iconico, si assume la responsabilità di rappresentare l’unità e l’identità di una comunità dedita allo studio e alla formazione.

Library university city urban public project contemporarySettore ICAR/14 - Composizione Architettonica E Urbana
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Vitauta Lielā Kauņas universitātes-Latvijas Universitātes sadraudzības apliecinājums

2020

Raksts satur informāciju par Latvijas Universitātes Muzeja pārziņā esošo Vītauta Lielā Kauņas universitātes-Latvijas Universitātes sadraudzības apliecinājumu LU galvenajā ēkā, kas uzdāvināts Latvijas Universitātes Simtgadē 2019. gadā. Rakstā tiek analizētas Latvijas-Lietuvas attiecības, skatoties LU vēstures kontekstā un uzsverot latviešu-lietuviešu tautu radniecību.

Lietuva:HUMANITIES and RELIGION::History and philosophy subjects::History subjects::History [Research Subject Categories]LU SimtgadeLithuaniaVitauta Lielā Kauņas universitāteBaltu tautasUniversity of Latvia 100Vytautas Magnus University of KaunasBalt people
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Pētera Stučkas Latvijas Valsts universitātē aizstāvētās disertācijas, 1945-1963: bibliogrāfisks rādītājs

1966

Teksts paralēli latviešu un krievu valodā

Literatūras zinātne - bibliogrāfiskais rādītājsVēsture - bibliogrāfiskais rādītājsArhitektūra - bibliogrāfiskais rādītājsPedagoģija - bibliogrāfiskais rādītājsĶīmija - bibliogrāfiskais rādītājsLatvijas UniversitāteBibliogrāfiskie rādītājiEkonomika - bibliogrāfiskais rādītājsMedicīna - bibliogrāfiskais rādītājsFizika - bibliogrāfiskais rādītājsFarmakoloģija - bibliogrāfiskais rādītājsUniversity of LatviaTehnika - bibliogrāfiskais rādītājsLatvijas Universitātes disertācijas - bibliogrāfiskais rādītājsHistory of the University of LatviaMatemātika - bibliogrāfiskais rādītājsĢeogrāfija - bibliogrāfiskais rādītājsTiesību zinātne - bibliogrāfiskais rādītājsFilozofija - bibliogrāfiskais rādītājsBioloģija - bibliogrāfiskais rādītājsValodniecība - bibliogrāfiskais rādītājs:SOCIAL SCIENCES::Social sciences::Education [Research Subject Categories]Latvijas Universitātes vēstureP. Stučkas Latvijas Valsts universitātes disertācijas - bibliogrāfiskais rādītājs
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IKT som læringsverktøy i matematikk : en studie av lærer- og elevrollen ved bruk av TI Interactive (og andre programmer) i 4 matematikklasser i vider…

2006

Masteroppgave i matematikkdidaktikk 2006 - Høgskolen i Agder, Kristiansand Temaet for masteroppgaven er en studie i hvordan bruk av IKT påvirker og forandrer læringsmiljøet i matematikk. Jeg har undersøkt anvendelsen av CAS-programmene TI Interactive (og Derive) i fire klasser på to videregående skoler, og prøvd å dokumentere hvordan slike dataprogram nyttes for å fremme matematisk forståelse. Bruken av CAS-verktøyet er studert ut fra både lærer- og elevperspektiv. Problemstilling: • Hvilke pedagogiske overveielser gjør læreren når han bruker IKT-programmet TI Interactive (og ev. andre programmer) som verktøy i læringsprosessen? • Hvordan lærer elevene matematikk ved hjelp av IKT-programmet…

MA500MA502VDP::Matematikk og naturvitenskap: 400::Matematikk: 410Agder University CollegeVDP::Samfunnsvitenskap: 200::Pedagogiske fag: 280::Fagdidaktikk: 283
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MALDI-TOF mass spectrometry identification of filamentous fungi in the clinical laboratory.

2014

Pôle MERS F. Dalle; International audience; This study aimed to validate the effectiveness of a standardised procedure for the MALDI-TOF mass spectrometry (MS)-based identification on a large sample of filamentous fungi routinely identified in university hospitals' laboratories. Non-dermatophyte filamentous fungi prospectively isolated in the routine activity of five teaching hospitals in France were first identified by conventional methods in each laboratory and then by MS in one centre. DNA sequence-based identification resolved discrepancies between both methods. In this study, of the 625 analysed filamentous fungi of 58 species, 501 (80%) and 556 (89%) were correctly identified by conve…

MALDI-TOFDermatologyBiologyMicrobiologyIdentification rateHospitals UniversitySpecies identificationHumansProspective StudiesArthrodermataceaefilamentous fungiFungiRoutine laboratoryGeneral MedicineSequence Analysis DNAUniversity hospitalMALDI-TOF Mass SpectrometryLarge sampleInfectious DiseasesLogistic Models[SDV.MP]Life Sciences [q-bio]/Microbiology and ParasitologySpectrometry Mass Matrix-Assisted Laser Desorption-IonizationidentificationIdentification (biology)Franceroutine laboratory
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Profesors Gunārs Sermons: biobibliogrāfiskais rādītājs

1994

Biobibliogrāfiskajā rādītājā ietverti tehnisko zinātņu doktora, profesora Gunāra Sermona publicētie darbi no 1958. līdz 1994.gadam, kā ari literatūra par viņu.

Magnetohydrodynamics - bibliographical indexЭлектромагнетизм - библиографический указательProfessors of the Latvian University:NATURAL SCIENCES::Physics [Research Subject Categories]Fizika - bibliogrāfiskais rādītājsElectromagnetism - bibliographical indexBiobibliogrāfiskie rādītājiMagnetohidrodinamika - bibliogrāfiskais rādītājsHistory of the University of LatviaМагнитогидродинамика - библиографический указательFizikas zinātņu profesori Latvijas UnivesitātēLatvijas Universitātes vēstureLatvijas Universitātes profesoriElektromagnētisms - bibliogrāfiskais rādītājs
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WNT Signaling Perturbations Underlie the Genetic Heterogeneity of Robinow Syndrome

2018

International audience; Locus heterogeneity characterizes a variety of skeletal dysplasias often due to interacting or overlapping signaling pathways. Robinow syndrome is a skeletal disorder historically refractory to molecular diagnosis, potentially stemming from substantial genetic heterogeneity. All current known pathogenic variants reside in genes within the noncanonical Wnt signaling pathway including ROR2, WNT5A, and more recently, DVL1 and DVL3. However, ∼70% of autosomal-dominant Robinow syndrome cases remain molecularly unsolved. To investigate this missing heritability, we recruited 21 families with at least one family member clinically diagnosed with Robinow or Robinow-like pheno…

Male0301 basic medicineCandidate geneFrizzledGROWTH-PLATEDEP DOMAINlnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4]PROTEINskeletal dysplasiaCraniofacial Abnormalities0302 clinical medicineLocus heterogeneityChromosome SegregationChild[ SDV.GEN.GH ] Life Sciences [q-bio]/Genetics/Human geneticsWnt Signaling PathwayGenetics (clinical)Genes DominantGeneticsWnt signaling pathwayMiddle AgedRobinow syndromeMENDELIAN-INHERITANCEPhenotypeChild PreschoolFemaleNEURAL-TUBE DEFECTSVERTEBRATE GASTRULATIONhuman embryonic developmentRare cancers Radboud Institute for Health Sciences [Radboudumc 9]AdultAdolescentCELL POLARITYLimb Deformities CongenitalMutation MissenseDwarfismBiologyArticledual molecular diagnosisDiagnosis DifferentialGenetic Heterogeneity03 medical and health sciencesFrizzledAll institutes and research themes of the Radboud University Medical CenterSkeletal disorderGeneticsmedicineHumansGenetic Association StudiesNeurodevelopmental disorders Donders Center for Medical Neuroscience [Radboudumc 7]Base SequenceGenetic heterogeneityMUTATIONSROR2medicine.diseaseDROSOPHILA TISSUE POLARITY030104 developmental biology[SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human geneticsUrogenital AbnormalitiesAUTOSOMAL-DOMINANT030217 neurology & neurosurgery
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NBEA : developmental disease gene with early generalized epilepsy phenotypes

2018

Abstract: NBEA is a candidate gene for autism, and de novo variants have been reported in neurodevelopmental disease (NDD) cohorts. However, NBEA has not been rigorously evaluated as a disease gene, and associated phenotypes have not been delineated. We identified 24 de novo NBEA variants in patients with NDD, establishing NBEA as an NDD gene. Most patients had epilepsy with onset in the first few years of life, often characterized by generalized seizure types, including myoclonic and atonic seizures. Our data show a broader phenotypic spectrum than previously described, including a myoclonic-astatic epilepsy-like phenotype in a subset of patients. Ann Neurol 2018;84:796-803

Male0301 basic medicineCarrier Proteins/geneticsCandidate geneDiseaseNeurodevelopmental Disorders/geneticsEpilepsy0302 clinical medicineNerve Tissue Proteins/geneticsChildAtonic seizureGeneticsddc:618PhenotypePhenotypeNeurologyChild PreschoolEpilepsy GeneralizedFemaleNEUROBEACHINRare cancers Radboud Institute for Health Sciences [Radboudumc 9]AdolescentGenotypeGeneralized/geneticsNerve Tissue ProteinsBiologyPATIENTArticle03 medical and health sciencesAll institutes and research themes of the Radboud University Medical CentermedicineJournal ArticleHumansGeneralized epilepsyAUTISMPreschoolGeneSPECTRUMNeurodevelopmental disorders Donders Center for Medical Neuroscience [Radboudumc 7]EpilepsyDELETIONNBEA encodes neurobeachinmedicine.diseaseFRAMEWORK030104 developmental biology[SDV.GEN.GH]Life Sciences [q-bio]/Genetics/Human geneticsNeurodevelopmental DisordersDE-NOVO MUTATIONSMutationAutismNeurology (clinical)Human medicineCarrier Proteins030217 neurology & neurosurgeryAnnals of neurology
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PD-1, PD-L1, and CD163 in pancreatic undifferentiated carcinoma with osteoclast-like giant cells: A expression patterns and clinical implications

2018

Undifferentiated carcinoma with osteoclast-like giant cells (UCOGC), a variant of pancreatic ductal adenocarcinoma (PDAC), has a striking genetic similarity to PDAC but a significantly improved overall survival. We hypothesize that this difference could be due to the immune response to the tumor, and as such, we investigated the expression of PD-1, PD-L1, and CD163 in a series of UCOGC. To this aim, 27 pancreatic UCOGCs (11 pure and 16 PDAC-associated), 5 extrapancreatic tumors with osteoclast-like giant cells and 10 pancreatic anaplastic carcinomas were immunostained using antibodies against PD-1, PD-L1, and CD163. In pancreatic UCOGCs, PD-L1 was expressed in neoplastic cells of 17 (63%) o…

Male0301 basic medicineIndianaProgrammed Cell Death 1 ReceptorOsteoclast; PDAC; Pancreatic Cancer; Tumor-Associated Macrophages; UCOGCOsteoclastsGiant CellsB7-H1 Antigen0302 clinical medicineTumor-Associated MacrophagesTumours of the digestive tract Radboud Institute for Molecular Life Sciences [Radboudumc 14]LymphocytesAged 80 and overbiologyTumor-associated macrophagesCell DifferentiationMiddle AgedOsteoclast; Pancreatic cancer; PDAC; Tumor-associated macrophages; UCOGC; 2734ImmunohistochemistryEuropePhenotypemedicine.anatomical_structure030220 oncology & carcinogenesisOsteoclastFemaleAntibodyCarcinoma Pancreatic DuctalAdult2734Antigens Differentiation MyelomonocyticReceptors Cell SurfaceUCOGCPathology and Forensic MedicinePancreatic Cancer03 medical and health sciencesImmune systemAll institutes and research themes of the Radboud University Medical CenterAntigens CDOsteoclastPD-L1Pancreatic cancerBiomarkers TumormedicineHumansHistiocyteAgedNeoplasm StagingPDACHistiocytesPancreatic cancermedicine.diseasePancreatic Neoplasms030104 developmental biologyGiant cellCancer researchbiology.proteinCD163
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Canakinumab for the Treatment of Autoinflammatory Recurrent Fever Syndromes.

2018

BACKGROUND: Familial Mediterranean fever, mevalonate kinase deficiency (also known as the hyperimmunoglobulinemia D syndrome), and the tumor necrosis factor receptor-associated periodic syndrome (TRAPS) are monogenic autoinflammatory diseases characterized by recurrent fever flares. METHODS: We randomly assigned patients with genetically confirmed colchicine-resistant familial Mediterranean fever, mevalonate kinase deficiency, or TRAPS at the time of a flare to receive 150 mg of canakinumab subcutaneously or placebo every 4 weeks. Patients who did not have a resolution of their flare received an add-on injection of 150 mg of canakinumab. The primary outcome was complete response (resolution…

Male0301 basic medicineInterleukin-1betaFamilial Mediterranean fever0302 clinical medicineMonoclonalChildMedicine(all)Mevalonate kinase deficiencySubcutaneousMedicine (all)Interleukin-1betaAntibodies MonoclonalGeneral MedicineFamilial Mediterranean FeverRecurrent feverChild PreschoolFemaleTumor necrosis factor alphaDrugInflammatory diseases Radboud Institute for Molecular Life Sciences [Radboudumc 5]medicine.drugAdultAdolescentFeverInjections SubcutaneousHereditary Autoinflammatory DiseasesAntibodies Monoclonal HumanizedAdolescent; Adult; Antibodies Monoclonal/administration & dosage; Antibodies Monoclonal/adverse effects; Antibodies Monoclonal/therapeutic use; Child; Child Preschool; Dose-Response Relationship Drug; Double-Blind Method; Familial Mediterranean Fever/drug therapy; Female; Fever/drug therapy; Hereditary Autoinflammatory Diseases/drug therapy; Humans; Injections Subcutaneous; Interleukin-1beta/antagonists & inhibitors; Male; Mevalonate Kinase Deficiency/drug therapy; Young AdultAntibodiesInjectionsDose-Response RelationshipYoung Adult03 medical and health sciencesAll institutes and research themes of the Radboud University Medical CenterDouble-Blind MethodGeneral & Internal MedicinemedicineHumansPreschoolAdolescent; Adult; Antibodies Monoclonal; Child; Child Preschool; Dose-Response Relationship Drug; Double-Blind Method; Familial Mediterranean Fever; Female; Fever; Hereditary Autoinflammatory Diseases; Humans; Injections Subcutaneous; Interleukin-1beta; Male; Mevalonate Kinase Deficiency; Young Adult; Medicine (all)030203 arthritis & rheumatologyDose-Response Relationship Drugbusiness.industryHereditary Autoinflammatory DiseasesHyperimmunoglobulinemia Dmedicine.diseaseCanakinumab030104 developmental biologyImmunologyMevalonate Kinase Deficiencybusiness
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