Search results for " Uterine Cervical Neoplasm"

showing 9 items of 19 documents

Overview of the benefitsand potential issues of the nonavalent HPV vaccine

2017

HPV-related diseases affect anogenital and oropharyngeal regions, heavily affecting the psychosexual dimension of both male and female individuals. HPV vaccination programs based on a bivalent or quadrivalent vaccine have opened broad perspectives for primary prevention. A nonavalent HPV vaccine (9vHPV), covering nine genotypes (HPV6, HPV11, HPV16, HPV18, HPV31, HPV33, HPV45, HPV52, and HPV58), might provide further improvement in terms of direct protection. In the present report, efficacy and safety data from 9vHPV vaccine development programs are examined. Efficacy data come from a pivotal trial, which was conducted among women aged 16–26 years randomly assigned to receive either the 9vHP…

MaleHPVmedicine.medical_specialtyUterine Cervical NeoplasmsDiseaseAnatomic region03 medical and health sciences0302 clinical medicineHPV nonavalent vaccinePrimary preventionEnvironmental healthmedicineHumansPapillomavirus Vaccines030212 general & internal medicineCervical cancer; HPV; HPV nonavalent vaccine; Prevention; Female; Humans; Male; Papillomaviridae; Papillomavirus Infections; Papillomavirus Vaccines; Randomized Controlled Trials as Topic; Uterine Cervical NeoplasmsPapillomaviridaeRandomized Controlled Trials as TopicGynecologyCervical cancerbusiness.industryPreventionPapillomavirus InfectionsObstetrics and GynecologyHpv vaccinationGeneral Medicinemedicine.disease030220 oncology & carcinogenesisCervical cancer; HPV; HPV nonavalent vaccine; PreventionCervical cancerFemalebusiness
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Human papilloma virus infection and vaccination: Pre-post intervention analysis on knowledge, attitudes and willingness to vaccinate among preadolesc…

2020

In recent years, vaccination coverage rates against Human Papilloma Virus (HPV) in Europe have shown a decreasing trend and remain below the required standard. The present study aims to assess knowledge and attitudes regarding HPV infection and vaccination among a representative sample of preadolescents of Palermo, Italy. A survey was carried out throughout two questionnaires, before and after carrying out an educational intervention scheduled during school hours. A total of 1702 students attending first-grade secondary schools of the province of Palermo were enrolled (response rate 68.9%). Students attending third classes (adj OR = 1.18

MaleHealth Knowledge Attitudes PracticeHealth Toxicology and Mutagenesislcsh:MedicineUterine Cervical NeoplasmsAdult women0302 clinical medicineSurveys and Questionnaires030212 general & internal medicineChildPapillomaviridaeSicilyPapillomavirus VaccineResponse rate (survey)PracticeSchoolsSchool-based interventionHealth KnowledgeVaccinationPreadolescent studentHPV infectionSexually transmitted diseaseVaccinationEuropeKnowledgeHPV infection; HPV vaccine; attitude; knowledge; preadolescent students; school-based intervention; sexually transmitted diseases; vaccination; willingness; Child; Europe; Female; Humans; Male; Papillomavirus Infections; Papillomavirus Vaccines; Patient Acceptance of Health Care; Schools; Sicily; Surveys and Questionnaires; Uterine Cervical Neoplasms; Vaccination; Health Knowledge Attitudes Practice; PapillomaviridaeFemalewillingnesspreadolescent studentssexually transmitted diseaseseducationWillingneArticlePost-interventionLikert scale03 medical and health sciences030225 pediatricsmedicineHumansHuman papilloma virus infectionPapillomavirus VaccinesSocioeconomic statusPapillomavirus InfectionHPV vaccinebusiness.industrylcsh:RPapillomavirus InfectionsPublic Health Environmental and Occupational HealthPatient Acceptance of Health Caremedicine.diseaseAttitudeAttitudesHPV infectionbusinessDemography
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Completion Surgery After Concomitant Chemoradiation in Locally Advanced Cervical Cancer: A Comprehensive Analysis of Pattern of Postoperative Complic…

2014

Background: We provided a comprehensive analysis of rate, pattern, and severity of early and late postoperative complications in a very large, single-institution series of locally advanced cervical cancer (LACC) patients administered CT/RT plus radical surgery (RS). Methods: A total of 362 consecutive LACC (FIGO stage IB2-IVA) patients were submitted to RS after CT/RT at the Gynecologic Oncology Unit of the Catholic University (Rome/Campobasso). At 4 weeks after CT/RT, patients were evaluated for objective response and triaged to radical hysterectomy and pelvic ± aortic lymphadenectomy. Surgical morbidity was classified according to the Chassagne's grading system. Results: Most cases underw…

Malecervical cancermedicine.medical_treatmentUterine Cervical NeoplasmsPostoperative ComplicationsAntineoplastic Combined Chemotherapy Protocols80 and overlocally advanced cervical cancerAdjuvantSettore MED/36 - DIAGNOSTICA PER IMMAGINI E RADIOTERAPIAAged 80 and overCervical cancerMedicine (all)Middle AgedPrognosisCombined Modality TherapyAdult; Aged; Aged; 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carcinoma; Squamous Cell; Chemotherapy; Adjuvant; Cisplatin; Combined Modality Therapy; Female; Fluorouracil; Follow-Up Studies; Humans; Hysterectomy; Lymph Node Excision; Male; Middle Aged; Neoplasm Grading; Postoperative Complications; Prognosis; Radiotherapy; Adjuvant; Survival Rate; Uterine Cervical Neoplasms; Young AdultSurvival RateOncologyChemotherapy AdjuvantCarcinoma Squamous CellFemaleFluorouracilAdultmedicine.medical_specialtyGynecologic oncologyHysterectomyYoung AdultmedicineHumansChemotherapyRadical HysterectomyRadical surgeryconcomitant chemoradiationSurvival rateAgedHysterectomyRadiotherapybusiness.industryCarcinomamedicine.diseaseSurgerySettore MED/40 - GINECOLOGIA E OSTETRICIASquamous CellConcomitantLymph Node ExcisionRadiotherapy AdjuvantSurgeryLymphadenectomyCisplatinNeoplasm GradingbusinessFollow-Up StudiesAnnals of Surgical Oncology
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Clinical outcome of recurrent locally advanced cervical cancer (LACC) submitted to primary multimodality therapies

2015

Abstract Objectives Recurrence of disease represents a clinical challenge in cervical cancer patients, especially when all available treatment modalities have been used in the primary setting. The aim of this study was to analyze the patterns of recurrence and their association with clinical outcome in locally advanced cervical cancer (LACC) patients submitted to primary chemoradiation (CTRT) followed by radical surgery (RS). Methods This study was conducted on 364 LACC patients treated with CTRT plus RS since January 1996 to July 2012. For each relapse, information on date of clinical/pathological recurrence, and pattern of disease presentation were retrieved. Post-relapse survival (PRS) w…

OncologyAdultmedicine.medical_specialtyUterine Cervical Neoplasmrecurrent cervical cancerPrognosimedicine.medical_treatmentUterine Cervical NeoplasmsDiseaseObstetrics and gynaecologyRetrospective StudieInternal medicinemedicineHumansRadical surgeryChemoradiation; Post-relapse survival; Prognosis; Radical hysterectomy; Recurrent cervical cancer; Adult; Chemoradiotherapy; Adjuvant; Female; Humans; Neoadjuvant Therapy; Neoplasm Recurrence; Local; Retrospective Studies; Survival Analysis; Treatment Outcome; Uterine Cervical NeoplasmschemoradiationSurvival analysisNeoadjuvant therapyAdjuvantRetrospective StudiesSettore MED/36 - DIAGNOSTICA PER IMMAGINI E RADIOTERAPIACervical cancerbusiness.industrypost-relapse survivalObstetrics and GynecologyRetrospective cohort studyChemoradiotherapy AdjuvantChemoradiotherapymedicine.diseaseSurvival AnalysisNeoadjuvant TherapySurgeryLog-rank testTreatment OutcomeNeoplasm RecurrenceSettore MED/40 - GINECOLOGIA E OSTETRICIAOncologyLocalradical hysterectomyFemaleSurvival AnalysiprognosisNeoplasm Recurrence LocalbusinessHuman
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Knowledge, opinions and attitudes of Italian mothers towards HPV vaccination and Pap test

2015

Aim This study evaluated the knowledge and attitudes of Italian mothers – whose daughters had been vaccinated in 2012 – towards primary (anti-HPV vaccination) and secondary (Pap test screening) cervical cancer prevention, as well as sources of information and mother-daughter communication on health issues. Methods The survey – part of a multicenter study carried out in 4 Italian cities (Ferrara, Rome, Cassino and Palermo) – was conducted through self-administered questionnaires. The first univariate analysis evaluated differences between mothers of under-18s and over-18s relative to knowledge and attitudes on HPV vaccination and Pap test. The second univariate analysis evaluated differences…

QuestionnairesUterine Cervical NeoplasmHealth Knowledge Attitudes PracticeCancer ResearchUterine Cervical NeoplasmsSurveys and QuestionnairesSurveys and QuestionnaireChildPapillomavirus VaccineCervical cancerUnivariate analysisPracticeMothermedicine.diagnostic_testHealth KnowledgeMedicine (all)VaccinationHpv vaccinationGeneral MedicineMiddle AgedVaccinationPap-testItalyOncologyFemaleHumanPapanicolaou TestAdultmedicine.medical_specialtyHuman papillomavirusAdolescentPublic health interventionsSocio-culturaleMothersJudgmentmedicineSexually transmitted infectionsHumansPap testPapillomavirus VaccinesAdolescent; Adult; Child; Female; Humans; Italy; Judgment; Middle Aged; Papanicolaou Test; Papillomavirus Infections; Papillomavirus Vaccines; Self Report; Surveys and Questionnaires; Uterine Cervical Neoplasms; Health Knowledge Attitudes Practice; VaccinationPapillomavirus InfectionSettore MED/42 - IGIENE GENERALE E APPLICATAGynecologySexually transmitted infectionbusiness.industryhuman papillomavirus; mothers; pap-test; sexually transmitted infections; vaccinationPapillomavirus InfectionsHuman papillomavirus; Mothers; Pap-test; Sexually transmitted infections; Vaccination; Adolescent; Adult; Child; Female; Humans; Italy; Judgment; Middle Aged; Papanicolaou Test; Papillomavirus Infections; Papillomavirus Vaccines; Questionnaires; Self Report; Uterine Cervical Neoplasms; Health Knowledge Attitudes Practice; Vaccination; Cancer Research; Oncology; Medicine (all)medicine.diseaseHuman papillomavirus; Mothers; Pap-test; Sexually transmitted infections; Vaccination; Adolescent; Adult; Child; Female; Humans; Italy; Judgment; Middle Aged; Papanicolaou Test; Papillomavirus Infections; Papillomavirus Vaccines; Self Report; Surveys and Questionnaires; Uterine Cervical Neoplasms; Health Knowledge Attitudes Practice; Vaccination; Cancer Research; Oncology; Medicine (all)Sexual intercourseHuman papillomaviruMulticenter studyFamily medicineAttitudesSelf Reportbusiness
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Robotic versus laparoscopic radical hysterectomy in early cervical cancer: A case matched control study

2018

Abstract Background This study aims at evaluating the feasibility, surgical outcome and oncological results observed after robotic radical hysterectomy (RH) compared to laparoscopy for patients with early stage cervical cancer (ECC) patients. Methods Between January 2010 and October 2016, 210 patients underwent RH for treatment of ECC: 70 underwent robotic approach (Cases), and 140 underwent laparoscopic approach (Controls). Results There was no statistically significant difference between the two approaches with regard to clinical patient characteristics and in terms of extent of RH and rate of pelvic and aortic lymphadenectomy. Operative time was significantly longer in the robotic versus…

Uterine Cervical NeoplasmTime Factorsmedicine.medical_treatmentEarly stage cervical cancerUterine Cervical Neoplasms0302 clinical medicinePostoperative ComplicationsRetrospective StudieLaparotomy80 and overMedicineEarly Detection of CancerEarly stage cervical cancer; Laparoscopy; Robotic surgery; Adult; Aged; Aged 80 and over; Female; Humans; Hysterectomy; Incidence; Italy; Laparoscopy; Middle Aged; Postoperative Complications; Retrospective Studies; Robotics; Survival Rate; Time Factors; Uterine Cervical Neoplasms; Young Adult; Early Detection of Cancer; Neoplasm Staging; Surgery; OncologyAged 80 and over030219 obstetrics & reproductive medicineIncidenceGeneral MedicineRoboticsMiddle AgedSurvival RateOncologyItaly030220 oncology & carcinogenesisFemaleHumanAdultmedicine.medical_specialtyTime FactorHysterectomy03 medical and health sciencesYoung AdultHumansRobotic surgeryRadical surgeryRadical HysterectomySurvival rateRetrospective StudiesAgedNeoplasm StagingHysterectomybusiness.industryRobotic surgeryPerioperativeSurgeryRoboticSettore MED/40 - GINECOLOGIA E OSTETRICIASurgeryLymphadenectomyLaparoscopyPostoperative Complicationbusiness
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ASO Authors Reflections: Vaginectomy as Surgical Treatment of Recurrent Cervical Cancer

2020

medicine.medical_specialtyVaginal Neoplasmsmedicine.medical_treatmentMEDLINERecurrent cervical cancerUterine Cervical NeoplasmsColpotomyHysterectomyVaginectomyColpotomy; Female; Humans; Hysterectomy; Neoplasm Recurrence Local; Pregnancy; Uterine Cervical Neoplasms; Vaginal NeoplasmsNeoplasm RecurrenceSurgical oncologyPregnancymedicineHumansSurgical treatmentPregnancyHysterectomybusiness.industryGeneral surgeryVaginectomymedicine.diseaseOncologySurgeryFemaleNeoplasm Recurrence Localbusiness
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Minimally Invasive Approaches in Locally Advanced Cervical Cancer Patients Undergoing Radical Surgery After Chemoradiotherapy: A Propensity Score Ana…

2020

Abstract Purpose Chemoradiation (CT/RT) followed by radical surgery (RS) may play a role in locally advanced cervical cancer (LACC) patients with suboptimal response to CT/RT or in low-income countries with limited access to radiotherapy. Our aim is to evaluate oncological and surgical outcomes of minimally invasive radical surgery (MI-RS) compared with open radical surgery (O-RS). Patients and Methods Data for stage IB2–IVA cervical cancer patients managed by CT/RT and RS were retrospectively analyzed. Results Beginning with 686 patients, propensity score matching resulted in 462 cases (231 per group), balanced for FIGO stage, lymph node status, histotype, tumor grade, and clinical respons…

medicine.medical_specialtymedicine.medical_treatmentConcomitant Chemoradiation Neoadjuvant Chemotherapy Phase III Hysterectomy Radiation Therapy WomenUterine Cervical NeoplasmsHysterectomyDisease-Free Survival03 medical and health sciences0302 clinical medicinePhase IIIlocally advanced cervical cancer (LACC)locally advanced cervical cancerHumansMedicineWomenChemoradiotherapy; Disease-Free Survival; Female; Humans; Hysterectomy; Neoadjuvant Therapy; Neoplasm Recurrence Local; Neoplasm Staging; Propensity Score; Retrospective Studies; Uterine Cervical Neoplasms030212 general & internal medicineStage (cooking)Radical surgeryPropensity ScoreNeoadjuvant therapyNeoplasm StagingRetrospective StudiesCervical cancerHysterectomyRadiationbusiness.industrylocally advanced cervical cancer surgeryNeoadjuvant ChemotherapyRetrospective cohort studyChemoradiotherapyGynecologic Oncologymedicine.diseaseNeoadjuvant TherapySurgeryRadiation therapySettore MED/40 - GINECOLOGIA E OSTETRICIANeoplasm RecurrenceLocalOncology030220 oncology & carcinogenesisConcomitant ChemoradiationFemaleSurgeryTherapyNeoplasm Recurrence LocalbusinessChemoradiotherapy
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Evaluation of Surgical Outcomes of Abdominal Radical Hysterectomy and Total Laparoscopic Radical Hysterectomy for Cervical Cancer: A Retrospective An…

2022

Although a surgical approach is one of the key treatments for stages IA1-IIA2, results of the Laparoscopic Approach to Cervical Cancer (LACC) published in 2018 radically changed the field, since minimally invasive surgery was associated with a four-fold higher rate of recurrence and a six-fold higher rate of all-cause death compared to an open approach. We aimed to evaluate surgical outcomes of abdominal radical hysterectomy (ARH) and total laparoscopic radical hysterectomy (TLRH) for cervical cancer, including data collected before the LACC trial. In our retrospective analysis, operative time was significantly longer in TLRH compared to ARH (p < 0.0001), although this disadvantage could…

total laparoscopic radical hysterectomycervical cancerHealth Toxicology and Mutagenesiscervical cancer; abdominal radical hysterectomy; total laparoscopic radical hysterectomy; minimally invasive surgery; surgical outcomesPublic Health Environmental and Occupational HealthUterine Cervical NeoplasmsHysterectomysurgical outcomesSettore MED/40 - Ginecologia E OstetriciaTreatment Outcomeabdominal radical hysterectomyHumansLaparoscopyFemaleabdominal radical hysterectomy; cervical cancer; minimally invasive surgery; surgical outcomes; total laparoscopic radical hysterectomy; Female; Humans; Retrospective Studies; Neoplasm Staging; Hysterectomy; Treatment Outcome; Uterine Cervical Neoplasms; Laparoscopyminimally invasive surgeryNeoplasm StagingRetrospective StudiesInternational Journal of Environmental Research and Public Health; Volume 19; Issue 20; Pages: 13176
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