Search results for " VAS"
showing 10 items of 1524 documents
Morphological, karyological and taxonomic remarks on Ferulago nodosa (L.) Boiss. (Apiaceae)
2012
Abstract Western (Sicilian) and eastern (Balcan-aegean) populations of the Balcan-tyrrhenian Ferulago nodosa are reported to be different in some morphological characters, and were considered different species by some authors in XIX century. In this work, fruit and pollen morphologies have been compared in Sicilian and Cretan plants; also, the chromosome number of Sicilian plants has been ascertained. Preliminary results highlight a general homogeneity between the two populations, nevertheless showing significant differences in some parameters (fruit form, pollen size). For this reason, and considering the geographic disjunction of the Sicilian plants, the two populations are proposed to be…
Diversity in the genus Hieracium Linnaeus s.str. (Asteraceae) in Sicily
2015
The present taxonomic and floristic knowledges on Hieracium L. s. str. in Sicily are commented. In total, 11 taxa occur in this island, 10 of which are endemic and 1 has a wider range. For each of these taxa, biological form, phenology, distribution, ecology, chromosome number, conservation, and taxonomy are taken in consideration. A key to the taxa is also provided.
Opposite vascular activity of (R)-apomorphine and its oxidised derivatives. Endothelium-dependent vasoconstriction induced by the auto-oxidation meta…
2003
We have synthetised a series of oxidised apomorphine derivatives (orto and para quinones 2-5), in order to analyse their vascular activity. We have performed radioligand binding assays on rat cortical membranes and functional studies on rat aortic rings. Instead the relaxant activity exhibited by (R)-apomorphine, o-quinones 2, 4, show contractile activity dependent on endothelium in rat aortic rings. Compound 2, the main metabolite of (R)-apomorphine auto-oxidation, was the product which showed enhanced contractile activity by a complex mechanism related to activation of Ca(2+) channels through release and/or inhibition of endothelial factors. Moreover, this compound disrupts the endothelia…
Vascular Activity of (-)-Anonaine, (-)-Roemerine and (-)-Pukateine, Three Natural 6a(R)-1,2-Methylenedioxyaporphines with Different Affinities for α1…
2004
We have studied the mechanism of action of three 6a( R)-1,2-methylenedioxyaporphines as vasorelaxant compounds. The alkaloids assayed showed different affinities for the three human cloned alpha (1)-adrenoceptor (AR) subtypes stably expressed in rat-1 fibroblasts, showing lower affinity for alpha(1B)-AR with regard to the alpha(1A)- or alpha(1D)-subtypes. These three natural compounds are more potent inhibitors of [ (3)H]-prazosin binding than of [ (3)H]-diltiazem binding to rat cerebral cortical membranes. As all these alkaloids inhibited noradrenaline (NA)-induced [ (3)H]-inositol phosphate formation in cerebral cortex and rat tail artery, they may be safely viewed as alpha (1)-AR antagon…
Exceptionally preserved soft parts in fossils from the Lower Ordovician of Morocco clarify stylophoran affinities within basal deuterostomes.
2019
10 pages; International audience; The extinct echinoderm clade Stylophora consists of some of the strangest known deuterostomes. Stylophorans are known from complete, fully articulated skeletal remains from the middle Cambrian to the Pennsylvanian, but remain difficult to interpret. Their bizarre morphology, with a single appendage extending from a main body, has spawned vigorous debate over the phylogenetic significance of stylophorans, which were long considered modified but bona fide echinoderms with a feeding appendage. More recent interpretation of this appendage as a posterior “tail-like” structure has literally turned the animal back to front, leading to consideration of stylophorans…
Approccio vascolare nell’ischemia mesenterica cronica
2019
Approccio vascolare nell’ischemia mesenterica cronica
Investigation on four centuripe vases (late 3rd-2nd cent. B.C.) by portable X-ray fluorescence and total reflectance-FTIR
2021
Abstract Four Centuripe vases dated back to the late 3rd-2nd centuries B.C. were analysed using imaging under visible and ultra-violet illumination as well as complementary non-invasive and non-destructive portable X-Ray Fluorescence (XRF) and Total Reflectance – Fourier Transform InfraRed (TR-FTIR) spectroscopies. The vases are of great importance since they represent a rare expression of the Hellenistic vase painting. Four specimens, a “pyxis”, a “lebes gamikos” and two “lekanides” decorated with figures of different type, are exhibited in the Antonino Salinas Archaeological Museum in Palermo-Italy. The investigation was aimed to identify the used pigments and the painting technique, to r…
Aparatūra “Lotoss” poliuretāna plastmasas detaļu atliešanai kosmosā
2020
1980. gadā kosmosa stacijā “Salūts” pirmoreiz kosmonautikas vēsturē tika realizēts putupoliuretāna ieguves eksperiments mikrogravitācijas apstākļos, kura rezultāta tika iegūtas jaunas atziņas par ķīmiski tehnoloģisko procesu norisi kosmosā. Kosmosā tapa Maskavas olimpisko spēļu simbola lācīša figūra. Iekārtu "Lotoss", kas pašreiz atrodas Latvijas Ķīmijas vēstures muzeja krājumā, LPSR Zinātņu Akadēmijas Koksnes ķīmijas institūtā izstrādājis latviešu ķīmiķis, ķīmijas doktors, izgudrotājs un gleznotājs Arnolds Alksnis, un tā domāta polimerizācijas reakciju pētīšanai bezsvara stāvoklī.
Arterial hypertension in cancer: The elephant in the room
2019
The great therapeutical success achieved by oncology is counterbalanced by growing evidences of cardiovascular (CV) toxicity due to many antineoplastic treatments. Cardiac adverse events may cause premature discontinuation of effective oncologic treatments or occur as late events undermining the oncologic success. Arterial hypertension is both the most common comorbidity in cancer patients and a frequent adverse effect of anticancer therapies. A pre-existing hypertension is known to increase the risk of other cardiac adverse events due to oncologic treatments, in particular heart failure. Moreover, as a strict association between cancer and CV diseases has emerged over the recent years, var…
Matrix Metalloproteases in Arterial Hypertension and their Trend after Antihypertensive Treatment
2017
<b><i>Background/Aims</i></b><b><i>:</i></b> Arterial hypertension is characterized by vascular remodelling, atherosclerosis and cardiovascular complications. Matrix metalloproteases (MPPs) are endopeptidases produced by all the cells present in the vascular wall and are involved in the regulation of the extracellular matrix protein turnover. MMPs contribute to blood vessel formation, remodelling, angiogenesis; whereas an altered expression or activity of MMPs or their tissue inhibitors (TIMPs) results correlated with the development and progression of cardiovascular complications. <b><i>Methods:</i></b> We examined the…