Search results for " VAS"

Interleukin-9 and T helper type 9 cells in rheumatic diseases

2016

Summary Interleukin (IL)-9 is a 28-30 kDa monomeric glycosylated polypeptide belonging to the IL-7/IL-9 family of proteins that bind to a composite receptor consisting of the private receptor IL-9R and the IL-2 receptor, gamma (IL-2RG), a common gamma subunit shared by the receptors of many different cytokines. The IL-9R is expressed widely and IL-9 impacts a number of effector cells, such as effector T cells, B cells, innate lymphoid cells, mast cells, polymorphonuclear cells, epithelial cells and smooth muscle cells, playing an important role in regulating inflammatory immunity. The critical role of IL-9 in promoting cellular and humoral immune responses makes it an important focus of pot…

[Management of patients with lymphatic diseases and lipoedema during the COVID-19 pandemic. Recommendations of the Spanish Group of Lymphology].

2020

Resumen La pandemia de COVID-19 es un desafío para el manejo de las patologías no COVID como la enfermedad linfática y el lipedema. La Telemedicina puede evitar la propagación del coronavirus. Se necesita un sistema que nos ayude a determinar la prioridad clínica y la selección de la asistencia presencial o telemática para cada paciente y la forma de realizarlas durante la pandemia. El Grupo Español de Linfología (GEL) ha realizado un documento de consenso con recomendaciones basadas en la bibliografía y experiencia clínica, como guía de práctica clínica en el manejo de anomalías linfáticas y lipedema durante la pandemia de COVID-19. Estas recomendaciones deben adaptarse a las característic…

How to diagnose and treat abdominal compartment syndrome after endovascular and open repair of ruptured abdominal aortic aneurysms

2014

Intra-abdominal hypertension (IAH) and abdominal compartment syndrome (ACS) are frequently encountered in patients treated for ruptured abdominal aortic aneurysms (rAAA) and carry a high morbidity and mortality risk. Despite these facts, IAH/ACS are still overlooked by many physicians, timely diagnosis is missed and treatment often inadequate. All staff involved in the treatment of rAAA should be aware of the risk factors predicting IAH/ACS, the profound implications and derangements on all organ systems, the clinical presentation, the appropriate measurement of intra-abdominal pressure to detect IAH/ACS and the current treatment options for these detrimental syndromes. This comprehensive r…

Effects of clopidogrel, prasugrel and ticagrelor on endothelial function, inflammatory and oxidative stress parameters and platelet function in patie…

2014

Introduction Particularly in the setting of acute coronary syndromes, the interplay between vascular and platelet function has been postulated to have direct clinical implications. The present trial is designed to test the effect of clopidogrel, prasugrel and ticagrelor on multiple parameters of vascular function, platelet aggregation, oxidative and inflammatory stress before and up to 4 weeks after coronary artery stenting. Methods and analysis The study is designed as a three-arm, parallel design, randomised, investigator-blinded study. Patients with unstable angina or non-ST elevation myocardial infarction undergoing coronary intervention with a drug-eluting stent will be randomised to r…

Viipurin poliittiset jännitteet : tapahtumia ja historiografiaa

2019

"Rokote rikollisuutta vastaan?" : käsityksiä rikollisuuteen vaikuttamisesta kriminaalihuollon toimijoiden lehtikirjoituksissa 1953-1967

2008

Tämän tutkimukseni aiheena on 1950- ja 1960- luvuilla suomalaisen kriminaalihuoltotyön virallisena tahona toimineen Vankeusyhdistyksen julkaiseman ”Rikollisuutta vastaan” – lehden artikkeleissa esiintyneet käsitykset rikollisuuteen vaikuttamisesta. Tarkastelen sitä, millaisia käsityksiä rikollisuuteen vaikuttamisesta esitetään liittyen rikollisuuden ennaltaehkäisyyn sekä siihen vaikuttamiseen kriminaalipoliittisin keinoin, joista tärkeimpinä voidaan mainita rangaistusjärjestelmä sekä kriminaalihuoltotyö. Olen kiinnostunut siitä, miten nämä käsitykset esiintyvät tutkimusajankohdan yhteiskunnallisessa ja kriminaalipoliittisessa ilmapiirissä. Etenkin pyrin tulkitsemaan, miten kriminaalipoliitt…

Vääristikö Hannah Arendt totuutta?

2017

Cardiometabolic Alterations in the Interplay of COVID-19 and Diabetes: Current Knowledge and Future Avenues

2021

The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) (coronavirus disease 2019 [COVID-19]) pandemic has raged for almost two years, with few signs of a sustained abatement or remission [...]

Double Flow Bioreactor for In Vitro Test of Drug Delivery.

2015

In this work, double-structured polymeric scaffolds were produced, and a double flow bioreactor was designed and set up in order to create a novel system to carry out advanced in vitro drug delivery tests. The scaffolds, consisting of a cylindrical porous matrix, are able to host cells, thus mimicking a three-dimensional tumor mass: moreover, a “pseudo-vascular” structure was embedded into the matrix, with the aim of allowing a flow circulation. The structure that emulates a blood vessel is a porous tubular-shaped scaffold prepared by Diffusion Induced Phase Separation (DIPS), with an internal lumen of 2 mm and a wall thickness of 200 micrometers. The as-prepared vessel was incorporated…

Valor pronóstico de la resonancia magnética cardiaca tras un infarto agudo de miocardio con elevación del segmento ST

2011

INTRODUCCIÓN Las enfermedades cardiovasculares, y en concreto el infarto agudo de miocardio con elevación de ST (IAMEST) son una importante causa de mortalidad en los países desarrollados. La resonancia magnética cardiaca (RMC) es una técnica cada vez más usada tras un IAMEST, permite un análisis simultáneo y fiable de varios índices cardiacos, que han demostrado valor para predecir la recuperación de la función sistólica. No obstante, los datos sobre su valor pronóstico son escasos y no hay estudios que realicen un análisis exhaustivo de todos los índices. Esta información es imprescindible para que la RMC se incorpore definitivamente a nuestra práctica clínica habitual. OBJETIVOS - Valora…