Search results for " Vaccination"
showing 10 items of 226 documents
A systematic review of the literature on the human genetic variations in response to vaccination
2012
BACKGROUND: Vaccinomics is a term that refers to the investigation of heterogeneity of host genetic markers at the individual or population level that may result in variations of humoral, cell-mediated, and/or innate immune responses to vaccines. Studying genetic heterogeneity of human response to vaccines is supposed to both afford a better understanding of the way vaccine works, and help in developing future vaccines that are protective. With this premise in mind, we performed a systematic review of the literature on the studies concerning the association between human genetic variations in response to vaccination. METHODS: A detailed literature search on the case-control and cohort studi…
Public health strategies adopted to manage the increase of accesses to vaccination services, as a result of the application of the law 119/2017.
2020
Background and aim of the work: In response to the alarming reduction of vaccination coverage rates, Italian Ministry of Health approved the law number 119/2017, which has extended the number of mandatory vaccinations, for school attendance, from four to ten. The present study aims to evaluate accesses to the vaccination services of the Palermo Local Health Unit (LHU) and the variation of the vaccination coverage rates for hexavalent and measles, mumps, rubella and varicella (MMRV) vaccines, after the implementation of the law 119/2017. Methods: An extent of opening hours and an involvement of other health-care professionals in the vaccination services of the Palermo LHU have been adopted t…
Influenza vaccination among healthcare workers and absenteeism from work due to influenza-like illness in a teaching hospital in Palermo
2012
<p><strong>Background</strong>: Annual flu vaccination of healthcare workers (HCWs) is recommended worldwide as the best way to prevent influenza and to avoid its transmission. However, in several European Countries, vaccination rate among HCWs is still less than 25%. The aim of this study was to determine the HCW vaccination coverage during a three year period in a large University Hospital, identifying socio demographic and occupational variables involved in the decision to accept influenza vaccination. Moreover, for the 2007-2008 season, we also assessed the effectiveness of influenza vaccination in reducing influenza-related absenteeism.</p><p><strong>…
Current Progress in Particle-Based Systems for Transdermal Vaccine Delivery
2020
Transcutaneous immunization (TCI) via needle-free and non-invasive drug delivery systems is a promising approach for overcoming the current limitations of conventional parenteral vaccination methods. The targeted access to professional antigen-presenting cell (APC) populations within the skin, such as Langerhans cells (LCs), various dermal dendritic cells (dDCs), macrophages, and others makes the skin an ideal vaccination site to specifically shape immune responses as required. The stratum corneum (SC) of the skin is the main penetration barrier that needs to be overcome by the vaccine components in a coordinated way to achieve optimal access to dermal APC populations that induce priming of…
French Vaccine Pass to the Test of the Constitutional Council: Some Considerations in the Light of the European Convention on Human Rights
2022
On 21 January 2022 the French Constitutional Council issued a ruling on the constitutionality of the law which aimed to make the access to a very large number of places subject to a vaccine pass. Firstly, the essay illustrates the main points of the ruling with a particular focus on the legal criteria which constituted the parameters used by the French Constitutional Council, including a short explanation of the legal provisions rejected. The article then analyses the most recent judgement of the European Court of Human Rights (ECtHR) which regarded mandatory vaccinations. Specifically, the judgment focuses on the recent case Vavři¹ka and Others v. the Czech Republic which explained the mai…
COVID-19 Vaccination Willingness and Hesitancy in Patients With Inflammatory Bowel Diseases: Analysis of Determinants in a National Survey of the Ita…
2021
The coronavirus disease 2019 (COVID-19) pandemic has not finished yet, and the most promising option towards its ending is widespread vaccination. Because patients with inflammatory bowel diseases (IBDs), namely Crohn’s disease (CD) and ulcerative colitis (UC), often require immune-modifying treatment, which might increase the risk of opportunistic infection,1 their vaccination history for several infectious diseases is routinely checked, and when inadequate, vaccination is performed at diagnosis or ideally before immune suppressive treatment is started.1 However, IBD patients were not found to be at an increased risk of developing COVID-19 or of experiencing a more severe disease course.2
El Instituto Médico Valenciano y la difusión de la vacuna
2004
The Medical Valencian Institute promoted a campaign of smallpox free vaccination (1851- 1894) by means of humanized vaccine sent from England. It spread the vaccination for the whole Spain and published careful statistics of the vaccinations practised in the Bulletin of the Medical Valencian Institute. The National Institute of Vaccination (1871) did not recognize his labor and one denied to him the category of Provincial Institute of Vaccination.
Assessing vaccine efficacy for the prevention of acute otitis media by pneumococcal vaccination in children: a methodological overview of statistical…
2006
Acute otitis media (AOM) is the most common bacterial infectious disease among children. Vaccination is proposed to prevent otitis and several clinical trials were performed to assess the efficacy of pneumococcal vaccines. The way vaccine efficacy is analysed varies among trials. However, the clinical meaning of an estimate of vaccine effect and its statistical test depends on the applied statistical method. We aim to bring the meaning and validity of statistical trial results to the attention of researchers. We consider all methodological approaches for analysing vaccine efficacy applied in pneumococcal vaccination trials included in a recent Cochrane Review. We demonstrate how different m…
The Child Health Care System in Italy
2016
Pediatric care in Italy has been based during the last 40 years on the increased awareness of the importance of meeting the psychosocial and developmental needs of children and of the role of families in promoting the health and well-being of their children. The pediatric health care system in Italy is part of the national health system. It is made up of 3 main levels of intervention: first access/primary care, secondary care/hospital care, and tertiary care based on specialty hospital care. This overview will also include a brief report on neonatal care, pediatric preventive health care, health service accreditation programs, and postgraduate training in pediatrics. The quality of the Ital…
Italian association for the study of the liver position statement on SARS-CoV2 vaccination.
2021
The vaccination campaign against Sars-CoV-2 commenced in Italy at the end of December 2020. The first ones to receive the immunization against the virus were the health workers and the residents of nursing homes, following which the vaccine would be available for the entire population, beginning with the most vulnerable individuals. SARS-CoV2 vaccines have been demonstrated to be safe for the general population, although no data for patients with liver diseases or those having undergone liver transplantation are available so far. The present position statement AISF is an attempt to suggest, based on the published data on the impact of Sars-Cov-2 infection in patients with chronic liver dise…