Search results for " Variation"
showing 10 items of 1712 documents
Association analysis between gene variants of the tyrosine hydroxylase and the serotonin transporter in borderline personality disorder.
2010
For patients with borderline personality disorder (BPD), we previously reported an independent effect of the catechol-o-methyl-transferase (COMT) low-activity (Met(158)) allele and an interaction with the low-expression allele of the deletion/insertion (short/long or S/L, resp.) polymorphism in the serotonin transporter-linked promoter region (5-HTTLPR). The purpose of the present study was to extend these findings to the tyrosine hydroxylase (TH) Val(81)Met single nucleotide polymorphism (SNP), the 5-HTTLPR S/L polymorphism incorporating the recently described functional A/G SNP within the long allele of the 5-HTTLPR (rs25531) as well as the variable number of tandem repeat (VNTR) polymorp…
Sequential evolution of genotype GII.4 norovirus variants causing gastroenteritis outbreaks from 2001 to 2006 in Eastern Spain.
2008
Noroviruses are the most common cause of outbreaks of viral gastroenteritis worldwide. Norovirus outbreaks were surveyed in Catalonia and the region of Valencia (Eastern Spain) between January 2001 and December 2006 as part of the European Union funded network "Food-borne viruses in Europe". During this time the etiology and epidemiological features of 194 outbreaks of acute non-bacterial gastroenteritis were investigated and norovirus was identified as causing 169 (87.1%) of them. Molecular epidemiology of viral strains was studied by RT-PCR and sequencing part of the RNA polymerase gene in ORF1 from 153 outbreak strains. The most commonly identified norovirus genotype was GII.4 (71.9% of …
Systematic review of the diagnosis of gastric premalignant conditions and neoplasia with high-resolution endoscopic technologies
2013
Aim. The aim of the article is to systematically review the current evidence on the diagnostic use of narrow band imaging (NBI), flexible spectral imaging color enhancement (FICE) and endoscopic image enhancement technology i-scan endoscopies for gastric precancerous and cancerous lesions. Materials and methods. Original manuscripts were searched in PubMed until October 2012. Pertinent data were collected and pooled diagnostic accuracy measures were estimated when possible. Results. In total, 38 studies were evaluated. Thirty-one studies were included for NBI and 7 studies for FICE assessment in this systematic review. No article was found meeting inclusion criteria for i-scan endoscopy. Th…
Weight-bearing, muscle loading and bone mineral accrual in pubertal girls--a 2-year longitudinal study.
2007
Abstract Objectives: The mechanical environment is considered to be the most important determinant of bone strength. Local muscle force, in turn, is regarded as the largest source of loading applied to bones. However, the effect of weight-bearing on bone mineral accrual is unclear. Comparing the relationship between muscle force and bone mineral content (BMC) in the upper and lower limbs provides a means of investigating this issue. Subjects and methods : The study group comprised 258 healthy girls aged 10–13 years old at baseline. BMC, lean body mass (LM) and fat body mass (FM) of total body were assessed by dual-energy X-ray absorptiometry at baseline and 2 years after. The maximal isomet…
Studies on a measles virus variant inducing persistent infections in cultured cells
1976
Attempts were made to characterized by a plaque assay two variants of the Edmonston strain of measles virus and to obtain plaque purified virus populations. The UP non-cytocidal variant, in all the examined cell systems, mainly produced small but also large plaques; the DP cytocidal variant always large plaques. Three clones, UP-SP4, UP-LP4 and DP-LP4, were derived by plaque purfication respectively of the UP small plaque, UP large plaque and DP large plaque forming particles. The virus populations of the clones could be distinguished by some other biological and physical characters: cytopathic effect in roller tube cultures, growth potential in HeLa cells, thermal stability at 45 degrees C…
Detrimental noise effects on brain's speech functions.
2009
Background noise has become part of our everyday life in modern societies. Its presence affects both the ability to concentrate and communicate. Some individuals, like children, the elderly, and non-native speakers have pronounced problems in noisy environments. Here we review evidence suggesting that background noise has both transient and Sustained detrimental effects on central speech processing. Studies on the effects of noise on neural processes have demonstrated hemispheric reorganization in speech processing in adult individuals during background noise. During noise, the well-known left hemisphere dominance in speech discrimination became right hemisphere preponderant. Furthermore, l…
Italian version of qualiveen-30: Cultural adaptation of a neurogenic urinary disorder-specific instrument
2011
Purpose Qualiveen-30 is a neurological urinary disorder (UD)-specific health-related quality of life (HRQL) instrument, recommended in the European Association of Urology guideline 2008. The objective is to complete the cultural adaptation of Qualiveen-30 into Italian. Materials and Methods One hundred and twenty eight Italian-speaking spinal cord injury (SCI) patients completed Qualiveen-30 and the SF-12 physical and mental component (PC and MC) at enrolment and 4 weeks later. At follow-up, patients also made global ratings of change (GRC) in urinary HRQL (GRC). Results Qualiveen-30 proved reliable (intraclass correlation coefficients of four domains: 0.77–0.90). Correlations with SF-12 an…
Generic Health-Related Quality of Life May Not Be Associated with Weight Loss 4 Years After Bariatric Surgery: a Cross-Sectional Study
2018
Background: There seem to exist a belief that weight-loss is proportionally associated with improvement of health-related quality of life (HRQoL) after bariatric surgery. HRQoL is a complex multidimensional construct of one’s perception of health and well-being and is measured through generic and disease specific questionnaires. Objectives: This study aimed to test the associations between weight-loss after bariatric surgery, and both generic and obesity-specific HRQoL, and mental distress, controlling for other patient characteristics. Methods: The study was conducted at the Department of Surgery at Haugesund Hospital (Norway) based on a cohort of bariatric surgery patients operated betwee…
Neurotropism in newborn hamsters of plaque purified measles virus clones
1976
Three plaque purified measles virus clones displayed a different neurotropism in newborn hamsters.
European vestibular experiments on the Spacelab-1 mission: 7. Ocular counterrolling measurements pre- and post-flight.
1986
The static ocular counterrolling (OCR) of the four scientific crew members in the first Spacelab mission was measured during baseline-data-collection before and after the flight of SL-1. It was presumed that the modification of otolithic responses during spaceflight will be reflected in specific changes of the OCR-gain on the first days after recovery. The magnitude of OCR was determined analysing colour-transparencies of subjects right eyes that were produced in different positions of lateral body tilt. In general, one subject did not show any changes at all; three subjects exhibited a significant decrease of OCR-gain after exposure to weightlessness, whereby differences could be found bet…