Search results for " Ventilation"
showing 10 items of 372 documents
Respiratory support techniques to avoid desaturation in critically ill patients requiring endotracheal intubation: A systematic review and meta-analy…
2017
Abstract Purpose To evaluate which respiratory support method for critically ill patients undergoing endotracheal intubation (ETI) is associated with less desaturation. Methods We searched PubMed, Cochrane Library, Scopus and CINAHL databases. We included randomized (RCT) and non-randomized (non-RCT) studies investigating any method of respiratory support before/during ETI compared to a reference control. Results Apneic oxygenation (ApOx) was the most commonly investigated respiratory support technique for critically ill patients undergoing intubation (4 RCTs, 358 patients). Three of these studies investigated high-flow nasal cannula (HFNC) for ApOx while standard nasal cannula was used in …
Assessment of regional ventilation distribution: comparison of vibration response imaging (VRI) with electrical impedance tomography (EIT)
2013
BACKGROUND: Vibration response imaging (VRI) is a bedside technology to monitor ventilation by detecting lung sound vibrations. It is currently unknown whether VRI is able to accurately monitor the local distribution of ventilation within the lungs. We therefore compared VRI to electrical impedance tomography (EIT), an established technique used for the assessment of regional ventilation. METHODOLOGY/PRINCIPAL FINDINGS: Simultaneous EIT and VRI measurements were performed in the healthy and injured lungs (ALI; induced by saline lavage) at different PEEP levels (0, 5, 10, 15 mbar) in nine piglets. Vibration energy amplitude (VEA) by VRI, and amplitudes of relative impedance changes (rel.ΔZ) …
Oleic Derivatives of Dopamine and Respiration
2018
Ventilatory inhibition is considered an undesirable pharmacological side effect of pharmacotherapy in neurodegenerative conditions underlain by brain dopamine deficiency. In this context, oleic derivatives of dopamine or N-acyl-dopamines are novel substances that may be of high therapeutic interest as having the ability to cross the blood-brain barrier and acting in dopamine-like manner. In the present study we seek to define the influence of N-acyl-dopamines on lung ventilation and its hypoxic responses in the rat. We found that N-oleoyl-dopamine decreased both normoxic and peak hypoxic ventilation in response to 8% acute hypoxia, on average, by 31% and 41%, respectively. Its metabolite, 3…
The Association of Intraoperative driving pressure with postoperative pulmonary complications in open versus closed abdominal surgery patients – a po…
2021
Abstract Background It is uncertain whether the association of the intraoperative driving pressure (ΔP) with postoperative pulmonary complications (PPCs) depends on the surgical approach during abdominal surgery. Our primary objective was to determine and compare the association of time–weighted average ΔP (ΔPTW) with PPCs. We also tested the association of ΔPTW with intraoperative adverse events. Methods Posthoc retrospective propensity score–weighted cohort analysis of patients undergoing open or closed abdominal surgery in the ‘Local ASsessment of Ventilatory management during General Anaesthesia for Surgery’ (LAS VEGAS) study, that included patients in 146 hospitals across 29 countries.…
Long-Term Ventilation in Neuromuscular Patients: Review of Concerns, Beliefs, and Ethical Dilemmas
2019
<b><i>Background:</i></b> Noninvasive mechanical ventilation (NIV) is an effective treatment in patients with neuromuscular diseases (NMD) to improve symptoms, quality of life, and survival. <b><i>Summary:</i></b> NIV should be used early in the course of respiratory muscle involvement in NMD patients and its requirements may increase over time. Therefore, training on technical equipment at home and advice on problem solving are warranted. Remote monitoring of ventilator parameters using built-in ventilator software is recommended. Telemedicine may be helpful in reducing hospital admissions. Anticipatory planning and palliative care should be …
Assessing the feasibility of cogeneration retrofit and district heating/cooling networks in small Italian islands
2017
Sustainability of energy supply strategies in small islands has been emerging as a severe issue, due to the large margins for improvement and rationalization of the most frequently adopted solutions. In most of the European islands, large amounts of heat are wasted by the operation of engine-based power plants; conversely, heat is produced by boilers (supplied by liquid fuels) or by electric equipment for a number of different uses, like domestic hot water production or space heating in winter. In this paper a techno-economic analysis is proposed to assess the feasibility of CHP-retrofit of the existing power plants and the possible utilization of the recovered heat to supply, via a distric…
PCM thermal storage design in buildings: Experimental studies and applications to solaria in cold climates
2017
Abstract As energy availability and demand often do not match, thermal energy storage plays a crucial role to take advantage of solar radiation in buildings: in particular, latent heat storage via phase-change material is particularly attractive due to its ability to provide high energy storage density. This paper analyzes the performance of a building-integrated thermal storage system to increase the energy performances of solaria in a cold climate. A wall opposing a highly glazed facade (south oriented) is used as thermal storage with phase change materials embedded in the wall. The study is based on both experimental and simulation studies. The concept considered is particularly suited t…
Redesign of a Rural Building in a Heritage Site in Italy: Towards the Net Zero Energy Target
2017
In order to achieve the ambitious objective of decarbonising the economy, it is mandatory, especially in Europe and in Italy, to include the retrofitting of existing buildings. In a country where a large share of existing buildings have heritage value, it is important to design effective retrofit solutions also in historical buildings. In this context, the paper describes the experience of re-design of an existing rural building located in Sicily, inside the ancient Greeks' “Valley of the Temples”. An energy audit was performed on the building, and its energy uses were thoroughly investigated. A building model was developed in the TRNSYS environment and its performances validated. The valid…
A preliminary method for the numerical prediction of the behavior of air bubbles in the design of Air Cavity Ships
2016
Air-cavity ships (ACS) are advanced marine vehicles that use air injection under hull to improve the vessel’s hydrodynamic characteristics. Although the concept of drag reduction by supplying gas under the ship’s bottom was proposed in the 19th century by Froude and Laval, at this time there are not many systematic studies on this subject. This paper is a preliminary work with the purpose of being a basic tool for the design of the ACS with computational fluid dynamic methods. The study aims to conduct a series of computational tests to compare the numerical models of bubble with experimental data. The first step of this study was to investigate the behavior of free bubble in water, conside…
Absorption equipment for energy savings: A case study in Sicily
2013
Abstract This paper considers a feasibility study on the recovery of the reject heat available from an electric utility with two units operating with 120-MW gas turbines; these units have a heat recovery system that feeds the district heating pipeline of an industrial consortium. Thus, feeding the expeller of the absorption equipment installed in a cooling plant for foodstuff stocking represents an opportunity for the feasibility study. This plant operates at both 0 °C and −18 °C. The feasibility study covers two aspects: (1) the technical feasibility of a suitable absorption cooling plant that uses two separate pieces of absorption equipment working with the pair ammonia–water and (2) the …