Search results for " WAVE"
showing 10 items of 2296 documents
Nanoprobing the acidification process during intracellular uptake and trafficking
2015
Abstract Many nanoparticular drug delivery approaches rely on a detailed knowledge of the acidification process during intracellular trafficking of endocytosed nanoparticles (NPs). Therefore we produced a nanoparticular pH sensor composed of the fluorescent pH-sensitive dual wavelength dye carboxy seminaphthorhodafluor-1 (carboxy SNARF-1) coupled to the surface of amino-functionalized polystyrene NPs (SNARF-1-NP). By applying a calibration fit function to confocal laser scanning microscopy (CLSM) images, local pH values were determined. The acidification and ripening process of endo/lysosomal compartments containing nanoparticles was followed over time and was found to progress up to 6h to …
Dyakonov-like surface waves in semi-infinite metal-dielectric lattices
2012
We demonstrated the existence of Dyakonov-like surface waves propagating at the boundary between a metal-insulator lattice and an isotropic dielectric. A range of propagation angles substantially greater than that for conventional birefringent materials is obtained, and with reasonably small losses.
Vers le contrôle de l'alignement et de l'orientation : théorie et expérience
2010
This thesis is about the control and characterisation of the alignment and orientation of molecules by ultra short laser pulses on a theoretical and experimental approach. Alignment corresponds to a symmetric angular distribution of the molecular axis peaked along the laser field axis, whereas orientation provides an asymmetric distribution favouring one spatial direction. Orientation by sudden two-colour (2+1) pulses is studied extensively for the non resonant case and conditions required for achieving significant orientation are explored. A second two-colour scheme, where the second harmonic is in quasi resonance with a vibrational level of the molecule, is also presented and discussed. T…
Deconvolution by Regularized Matching Pursuit
2014
In this chapter, an efficient method that restores signals from strongly noised blurred discrete data is presented. The method can be characterized as a Regularized Matching Pursuit (RMP), where dictionaries consist of spline wavelet packets. It combines ideas from spline theory, wavelet analysis and greedy algorithms. The main distinction from the conventional matching pursuit is that different dictionaries are used to test the data and to approximate the solution. In addition, oblique projections of data onto dictionary elements are used instead of orthogonal projections, which are used in the conventional Matching Pursuit (MP). The slopes of the projections and the stopping rule for the …
Efficacy of dulaglutide on vascular health indexes in subjects with type 2 diabetes: a randomized trial
2021
Abstract Background Recent cardiovascular outcome trials have shown significant reductions in major cardiovascular (CV) events with glucagon-like peptide (GLP)-1 receptor agonists. Additionally, adjunctive surrogates for cardiovascular risk validated by some studies include arterial stiffness and endothelial function indexes. To date, no randomized trial has addressed the possible effects of antidiabetic interventional drugs such as GLP1 agonists on endothelial and arterial stiffness indexes as surrogate markers of vascular damage. Aims We aimed to evaluate metabolic efficacy and surrogate vascular efficacy endpoints of once-weekly dulaglutide (1.5 mg) plus traditional antidiabetic treatmen…
3-D attenuation image of fluid storage and tectonic interactions across the Pollino fault network
2021
SUMMARYThe Pollino range is a region of slow deformation where earthquakes generally nucleate on low-angle normal faults. Recent studies have mapped fault structures and identified fluid-related dynamics responsible for historical and recent seismicity in the area. Here, we apply the coda-normalization method at multiple frequencies and scales to image the 3-D P-wave attenuation (QP) properties of its slowly deforming fault network. The wide-scale average attenuation properties of the Pollino range are typical for a stable continental block, with a dependence of QP on frequency of $Q_\mathrm{ P}^{-1}=(0.0011\pm 0.0008) f^{(0.36\pm 0.32)}$. Using only waveforms comprised in the area of seism…
The mechanically-based approach to 3D non-local linear elasticity theory: Long-range central interactions
2010
Abstract This paper presents the generalization to a three-dimensional (3D) case of a mechanically-based approach to non-local elasticity theory, recently proposed by the authors in a one-dimensional (1D) case. The proposed model assumes that the equilibrium of a volume element is attained by contact forces between adjacent elements and by long-range forces exerted by non-adjacent elements. Specifically, the long-range forces are modelled as central body forces depending on the relative displacement between the centroids of the volume elements, measured along the line connecting the centroids. Further, the long-range forces are assumed to be proportional to a proper, material-dependent, dis…
Effect of pressure on structural properties and energy band gaps of γ-InSe
2003
We have investigated theoretically the effect of hydrostatic pressure on interatomic bond lengths and energy band gaps of γ-InSe. Total energy calculations were performed using the linear augmented plane wave (LAPW) method, taking into account scalar relativistic corrections as well as spin-orbit coupling. Internal structural parameters were optimized for different pressures by adopting as input the unit cell parameters known from experiment. Our theoretical results for the nearest-neighbor In-Se bond length are in excellent agreement with a recent experimental determination from high-pressure EXAFS measurements. The covalent In-In bond is found to be more compressible than the partially io…