Search results for " Well-Being"

Genome-wide association scan of attention deficit hyperactivity disorder

2008

Contains fulltext : 70191.pdf (Publisher’s version ) (Closed access) Results of behavioral genetic and molecular genetic studies have converged to suggest that genes substantially contribute to the development of attention deficit/hyperactivity disorder (ADHD), a common disorder with an onset in childhood. Yet, despite numerous linkage and candidate gene studies, strongly consistent and replicable association has eluded detection. To search for ADHD susceptibility genes, we genotyped approximately 600,000 SNPs in 958 ADHD affected family trios. After cleaning the data, we analyzed 438,784 SNPs in 2,803 individuals comprising 909 complete trios using ADHD diagnosis as phenotype. We present t…

The emergence of Vibrio pathogens in Europe : ecology, evolution, and pathogenesis (Paris, 11-12th March 2015)

2015

Global change has caused a worldwide increase in reports of Vibrio-associated diseases with ecosystem-wide impacts on humans and marine animals. In Europe, higher prevalence of human infections followed regional climatic trends with outbreaks occurring during episodes of unusually warm weather. Similar patterns were also observed in Vibrio-associated diseases affecting marine organisms such as fish, bivalves and corals. Basic knowledge is still lacking on the ecology and evolutionary biology of these bacteria as well as on their virulence mechanisms. Current limitations in experimental systems to study infection and the lack of diagnostic tools still prevent a better understanding of Vibrio…

Revisiting the happy-productive worker thesis from a eudaimonic perspective: a systematic review

2021

The happy-productive worker thesis (HPWT) is considered the Holy Grail of management research, and it proposes caeteris paribus, happy workers show higher performance than their unhappy counterparts. However, eudaimonic well-being in the relationship between happiness and performance has been understudied. This paper provides a systematized review of empirical evidence in order to make a theoretical contribution to the happy-productive worker thesis from a eudaimonic perspective. Our review covers 105 quantitative studies and 188 relationships between eudaimonic well-being and performance. Results reveal that analyzing the eudaimonic facet of well-being provides general support for the HPWT…

Unaccompanied minors in Sicily: promoting conceptualizations of child well-being through children’s own subjective realities

2020

Understanding unaccompanied minors’ (UAMs’) individual migration journeys and aspirations and hopes helps make sense of the meaning they ascribe to their personal and social reality in their quest for integration and mobility. Although the well-being of children is considered to be of the utmost importance in contemporary times, we still lack good evidence of what children themselves regard as key facets of this, from their own life experiences. Identifying different domains and dimensions of children’s well-being and touching upon its multifaceted nature, this study presents an alternative framework, showing how the quality of the reception path is fundamental to having successful results …

Toxicity of binary mixtures of Cu, Cr and As to the earthworm Eisenia andrei

2020

AbstractChromated copper arsenate (CCA) mixtures were used in the past for wood preservation, leading to large scale soil contamination. This study aimed at contributing to the risk assessment of CCA-contaminated soils by assessing the toxicity of binary mixtures of copper, chromium and arsenic to the earthworm Eisenia andrei in OECD artificial soil. Mixture effects were related to reference models of Concentration Addition (CA) and Independent Action (IA) using the MIXTOX model, with effects being related to total and available (H2O and 0.01 M CaCl2 extractable) concentrations in the soil. Since only in mixtures with arsenic dose-related mortality occurred (LC50 92.5 mg/kg dry soil), it wa…

Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen

2019

BACKGROUND: Although diabetic kidney disease demonstrates both familial clustering and single nucleotide polymorphism heritability, the specific genetic factors influencing risk remain largely unknown.METHODS: To identify genetic variants predisposing to diabetic kidney disease, we performed genome-wide association study (GWAS) analyses. Through collaboration with the Diabetes Nephropathy Collaborative Research Initiative, we assembled a large collection of type 1 diabetes cohorts with harmonized diabetic kidney disease phenotypes. We used a spectrum of ten diabetic kidney disease definitions based on albuminuria and renal function.RESULTS: Our GWAS meta-analysis included association result…

Life satisfaction and tax morale: The role of trust in government and cultural orientation

2022

Taxes are essential for a government to function correctly, because they fund public services and promote long-term growth in a country. Tax morale is a positive attitude toward taxation shaped by extrinsic and intrinsic motivations, including numerous psychological factors. However, these factors are far from completely clear and a better understanding of what drives tax morale can greatly help governments in the design of tax policies and their administration. In this paper we test the novel hypothesis that life satisfaction is one of the psychological aspects affecting tax morale. Using longitudinal data from the World Value Survey, we show that people more satisfied with their own life …

Valuing water supply infrastructure improvements using life satisfaction data as a complement to contingent valuation

2019

VALIDITY AND RELIABILITY OF THE FLOURISHING SCALE: LATVIAN VERSION

2021

The objective of this study was to assess the psychometric properties of the Latvian version of the Flourishing Scale (FS), created by Diener et al. (2010). FS is a brief self-report measure of the respondent’s well-being and success in areas of relationships, self-esteem, purpose, and optimism. The scale provides a single score across 8 items. The original FS was translated to Latvian and then back to English. The Satisfaction with Life Scale and Meaning in Life Questionnaire was applied for testing the convergent validity of the FS. Participants of the study were 191 people, ranged in age from 19 to 68 (159 women, mean age M = 30.62, SD = 9.50). Reliability analysis, exploratory and confi…

Predicting Well-Being Among the Elderly: The Role of Coping Strategies

2020

Objectives: This study aims to give a wider view on the role of coping strategies on elderly’s well-being, by means of literature-based competitive structural equation models (SEM). Methods: 857 older adults were surveyed with Ryff’s scales of Psychological Well-being and the Coping Strategies Questionnaire. Competitive full SEMs were tested. Results: The best fitting model was the one in which the religious coping dimension was removed, leaving the remaining dimensions defined by problem- and emotion-focused coping, which explained both psychological and subjective well-being factors (χ2(46)=165.910, p<.001; CFI=.906; GFI=.957; RMSEA=.058 [.048, .067]). Discussion: Results pointed the rele…