Search results for " acting"

showing 10 items of 80 documents

Hepatocellular carcinoma recurrence after direct-acting antiviral therapy: An individual patient data meta-analysis

2021

ObjectiveThe benefit of direct-acting antivirals (DAAs) against HCV following successful treatment of hepatocellular carcinoma (HCC) remains controversial. This meta-analysis of individual patient data assessed HCC recurrence risk following DAA administration.DesignWe pooled the data of 977 consecutive patients from 21 studies of HCV-related cirrhosis and HCC, who achieved complete radiological response after surgical/locoregional treatments and received DAAs (DAA group). Recurrence or death risk was expressed as HCC recurrence or death per 100 person-years (100PY). Propensity score-matched patients from the ITA.LI.CA. cohort (n=328) served as DAA-unexposed controls (no-DAA group). Risk fac…

medicine.medical_specialtyCarcinoma HepatocellularCirrhosisAntiviral AgentsGastroenterology03 medical and health sciences0302 clinical medicineInternal medicineantiviral therapymedicineHumansPropensity Scoreantiviral therapy; hepatocellular carcinoma; meta-analysisbusiness.industryLiver NeoplasmsGastroenterologyAntiviral therapyPatient datahepatocellular carcinomamedicine.disease3. Good healthmeta-analysis030220 oncology & carcinogenesisMeta-analysisHepatocellular carcinomaRelative riskCohort030211 gastroenterology & hepatology[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologieNeoplasm Recurrence LocalbusinessDirect acting
researchProduct

Treatment of elderly HCV patients with severe fibrosis: safety and efficacy data from RESIST-HCV, a large regional database

2016

medicine.medical_specialtyDirect Acting Antivirals (DAAs); chronic hepatitis C; cirrhosisHepatologybusiness.industrycirrhosisGastroenterologyPhysical therapyMedicinechronic hepatitis CSevere fibrosisbusinessIntensive care medicineDirect Acting Antivirals (DAAs)
researchProduct

Impact of direct-acting antivirals (DAAs) on cardiovascular diseases in patients with chronic hepatitis C

2021

INTRODUCTION: In the last years the Hepatitis C virus (HCV) infection was a relevant public health problem due to the large number of affected people worldwide and the impact on hepatic and extrahepatic complications. The availability of direct-acting antivirals (DAAs) and the very high rate of sustained virological response (SVR) after treatment has radically changed the course of HCV chronic infection. EVIDENCE ACQUISITION: We searched PubMed for articles published between January 1, 1995, through December 31, 2020, in English language. EVIDENCE SYNTHESIS: Robust evidence showed a close link between HCV infection and development of cardiovascular disease (CVD), as result of the atherogeni…

medicine.medical_specialtyEndocrinology Diabetes and MetabolismHepatitis C virusMEDLINEHepacivirusDiseaseDIRECT ACTING ANTIVIRALSmedicine.disease_causeAntiviral AgentsVirusInternal medicineInternal MedicinemedicineHumansHepatitis chronic Cardiovascular diseases Antiviral agentsIn patientbusiness.industryPublic healthGastroenterologyvirus diseasesHepatitis C Chronicdigestive system diseasesChronic infectionCardiovascular DiseasesPersistent Infectionbusiness
researchProduct

Aclidinium, a New Long-Acting Antimuscarinic, Inhibits Cholinergic and Cigarette Smoke-Induced Up Regulation of Mucin MUC5AC Expression in Human Airw…

2009

medicine.medical_specialtyEndocrinologyLong actingDownregulation and upregulationbusiness.industryInternal medicineMucinmedicineCholinergicCigarette smokeHuman airwayPharmacologybusiness
researchProduct

AISF position paper on HCV in immunocompromised patients.

2018

Abstract This report summarizes the clinical features and the indications for treating HCV infection in immunocompromised and transplanted patients in the Direct Acting Antiviral drugs era.

medicine.medical_specialtyTransplant RecipientComorbidityAntiviral AgentsOrgan transplantation03 medical and health sciencesImmunocompromised Host0302 clinical medicineInternal medicineNeoplasmsmedicineImmunocompromised patientHumansChronicIntensive care medicineAntiviral AgentHepatologybusiness.industryGastroenterologyHepatologyHepatitis C Chronicmedicine.diseaseComorbidityHepatitis COrgan transplantHCV; Immunocompromised patients; Organ transplant; Hepatology; GastroenterologyTransplant RecipientsHCV; Immunocompromised patients; Organ transplant; Antiviral Agents; Comorbidity; Hepatitis C Chronic; Humans; Immunocompetence; Italy; Neoplasms; Transplant Recipients; Immunocompromised HostItaly030220 oncology & carcinogenesisHCVHCV Immunocompromised patients Organ transplantPosition paperNeoplasmImmunocompromised patients030211 gastroenterology & hepatologyImmunocompetencebusinessImmunocompetenceDirect actingHumanDigestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver
researchProduct

Economic Aspects in the Treatment of Schizophrenia in Italy: Cost Consequences of an Early Long-acting Injectable Anti-Psychotics (lais) Approach

2017

PurposeThe aim of this analysis was to evaluate the economic consequences of a new treatment approach in the treatment of schizophrenia in the Italian setting. In terms of direct costs, in Italy was estimated that the main driver were represented by hospitalization and residential cost (71% of total direct cost per patient), followed by semi-residential services (13%), anti-psychotic and other drugs (8%) and ambulatory services (8).MethodsA probabilistic cost consequence model was developed to estimate the potential cost reductions derived from an early treatment with atypical long-acting injectable anti-psychotics (aLAIs) drugs. A systematic literature review was carried out to identify di…

medicine.medical_specialtybusiness.industryCost consequencesHealth PolicySchizophrenia (object-oriented programming)Public Health Environmental and Occupational Healthmedicine.diseaseCost reductionPsychiatry and Mental healthIndirect costsLong actingSystematic reviewSchizophreniaEnvironmental healthmedicineScenario analysisPsychiatrybusinessEconomic consequencesEuropean Psychiatry
researchProduct

The use of long-acting forms of gonadotropin-releasing hormone analogs (GnRHa Depot) increase miscarriage rates in oocyte donation cycles.

2001

medicine.medical_specialtybusiness.industryDepotObstetrics and GynecologyGonadotropin-releasing hormonemedicine.diseaseMiscarriageLong actingEndocrinologyReproductive MedicineOocyte donationInternal medicinemedicinebusinessFertility and Sterility
researchProduct

Variation of the Effect of Surface Acting on General Health and Need for Recovery Based on the Frequency of Interactions at Work: A Multi-Group Analy…

2022

stressneed for recoverywellbeingemotional laborsurface actinghealth
researchProduct

The Role of Surface Acting in the Relationship between Job Stressors, General Health and Need for Recovery Based on the Frequency of Interactions at …

2022

The aim of the study was to verify whether the frequency of face-to-face interactions with the public at work can reveal differences in how people react to emotional regulation demands. In particular, we investigated the mediating role of surface acting (a strategy of dealing with emotional dissonance) in the relationship between two typical job stressors (workload and mental load) and two outcomes closely related to work-related well-being: employees’ general health and the need for recovery. Prior studies investigating the detrimental effects of emotional dissonance mostly focused on service workers. However, in light of a survey conducted by the European Agency for Safety and Health at W…

surface actingHealth Toxicology and MutagenesisEmotionsPublic Health Environmental and Occupational HealthhealthWorkloadJob Satisfactionstressneed for recoverywellbeingemotional labor; surface acting; health; need for recovery; wellbeing; stressemotional laborSurveys and QuestionnairesQuality of LifeHumansSettore M-PSI/06 - Psicologia Del Lavoro E Delle OrganizzazioniWorkplaceInternational Journal of Environmental Research and Public Health; Volume 19; Issue 8; Pages: 4800
researchProduct

Ku teorii recytacji. Interdyscyplinarny charakter badań nad sztuką recytacji

2016

Artykuł zawiera przegląd stanowisk badawczych w odniesieniu do sztuki recytacji. Autorka wskazuje na recytację jako na zjawisko, którego rozumienie wymaga podejścia interdyscyplinarnego, uwzględniającego punkty widzenia wielu dyscyplin badawczych, jak chociażby językoznawstwa, literaturoznawstwa, teatrologii oraz estetyki. W perspektywie badawczej tych dwóch pierwszych dyscyplin recytacja ukazuje się jako sztuka wykonawcza, sztuka interpretacji zależna od literackiego tekstu. Perspektywa teatrologiczna z kolei ukazuje recytację w odniesieniu do teatru i sztuki aktorskiej. Jeżeli recytacja jest częścią mówienia scenicznego, to nie należy jej przeciwstawiać sztuce aktorskiej, lecz uznać, iż d…

sztuka; dzieło recytacyjne; interpretacja; aktorstwo; wygłoszenieart; recitative work (recitation work); interpretation; acting; deliveryLitteraria Copernicana
researchProduct