Search results for " activity"
showing 10 items of 4540 documents
Molecular Basis for Endocrine Disruption by Pesticides Targeting Aromatase and Estrogen Receptor
2020
The intensive use of pesticides has led to their increasing presence in water, soil, and agricultural products. Mounting evidence indicates that some pesticides may be endocrine disrupting chemicals (EDCs), being therefore harmful for the human health and the environment. In this study, three pesticides, glyphosate, thiacloprid, and imidacloprid, were tested for their ability to interfere with estrogen biosynthesis and/or signaling, to evaluate their potential action as EDCs. Among the tested compounds, only glyphosate inhibited aromatase activity (up to 30%) via a non-competitive inhibition or a mixed inhibition mechanism depending on the concentration applied. Then, the ability of the thr…
Biocontrol activities of Pseudomonas fluorescens against asparagus pathogen
2016
Pseudomonas spp. and their metabolites present environmentally friendly alternative to chemical products to improve plant growth in many different applications. Extensive studies have shown that these microorganisms and their metabolites could have an important role in agriculture and horticulture in improving crop productivity. The aim of the research was to assess a potential biological activity of Pseudomonas fluorescens against Fusarium oxysporum isolated from the spears of asparagus. The antagonistic properties of metabolites were assayed with a dual culture plate method on PDA and Czapek media for supernatants obtained from 6, 12, 24 and 48-hour culture of P. fluorescens. The culturin…
Critical thinking skills in classe tra sfida e impegno
2020
A scuola devono essere previsti ed attuati interventi sistematici che promuovano negli alunni abilità quali l’uso corretto di ragionamenti, la formulazione adeguata di giudizi, la generazione e l’espressione di idee originali, lo sviluppo di ipotesi per la soluzione di problemi, la costruzione di piani d’azione, l’assunzione di scelte autonome e controllate. L’espansione tecnologica alimenta piuttosto la difficoltà di bambini e ragazzi di organizzare i dati conoscitivi provenienti da più fonti, di selezionare e valutare le informazioni secondo scopi definiti. Si tratta di identificare azioni educative e procedure didattiche efficaci ad impegnare la capacità critica degli alunni. Il contesto…
Mitigation of the impact of stellar activity on observations of transiting planets
2023
La tesi si concentra sulla quantificazione dell'impatto dell'attività stellare sulle osservazioni dei pianeti in transito e sull'identificazione di una metodologia per correggere questi effetti. In particolare, viene approfondito l'effetto delle macchie stellari, sia non occultate che occulte. La presenza di macchie sul disco stellare visibile può distorcere la curva della luce di transito primaria in modo dipendente dalla lunghezza d'onda, mimando la presenza di un'atmosfera. Per tener conto di questo effetto, la tesi presenta un metodo innovativo per stimare le proprietà delle macchie e la loro distribuzione dalle osservazioni fuori transito e, su questa base, correggere le curve di luce …
Home Oral Care Domiciliary Protocol for the Management of Dental Erosion in Rugby Players: A Randomized Clinical Trial
2022
People performing regular physical activity are at high risk of dental erosion especially in cases of high sport drinks intake. Biomimetic hydroxyapatite-based oral hygiene products, like toothpastes and mouthwashes, have been investigated in recent years for their remineralizing activity on the teeth. The aim of the present study was to evaluate the efficacy of two different oral hygiene protocols, respectively consisting of the combination of a hydroxyapatite-based toothpaste plus mouthwash (Trial group) or toothpaste alone (Control Group). At baseline (T0), as well as at 15 days (T1), 30 days (T2) and 90 days (T3), the following clinical indexes were assessed: Basic Erosive Wear Examinat…
Psychological correlates of physical activity and exercise preferences in metropolitan and nonmetropolitan cancer survivors
2021
Objective Interventions to increase physical activity (PA) in cancer survivors have often adopted a ‘one‐size‐fits‐all’ approach, and may benefit from being tailored to psychological constructs associated with behavior. The study objective was to investigate the exercise preferences and psychological constructs related to PA among cancer survivors. Methods Post‐treatment colorectal, endometrial, and breast cancer survivors (n=183) living in metropolitan and non‐metropolitan areas completed survey measures of PA, exercise preferences, attitudes, self‐efficacy, perceived behavioral control (PBC), and intention toward PA. Results A structural equation model with adequate fit and quality indice…
Attitudes toward and motivation for PE: who collects the benefits of the subject?
2014
Background and purpose: Due to attitudinal and motivational aims in the national curriculum, and to lack of research on adolescents' experiences with physical education (PE) in Norway, the purposes of this study were to (1) attain data on attitudes toward PE and self-determined motivation for PE among a representative sample of adolescents (N = 2010) in middle school (grade 8–10/age 13–15) and high school (grade 11–13/age 16–19) in Norway, and (2) to explore the relationship between involvement in movement activities outside school and self-determined motivation in PE. Findings: The results showed that 43% of the adolescents were not happy with how PE is taught in Norwegian schools, and tha…
L'attività normativa del governo nel periodo 2017-2019
2022
L’articolo descrive l’attività normativa del governo nel periodo 2017-2019. Per quanto riguarda le procedure di programmazione e revisione della spesa pubblica, le riforme del 2016 finalizzate alla riduzione della spesa dei Ministeri hanno trovato applicazione solo nel 2017, mentre nel 2018 e nel 2019 ulteriori risparmi sono stati conseguiti mediante apposite previsioni delle leggi di bilancio. Le principali innovazioni in materia di liberalizzazione sono state portate a termine nel 2017, mentre non vi sono stati interventi rilevanti nel biennio successivo. Per quanto concerne il decentramento di funzioni amministrative, non si sono riscontrati progressi. Le politiche di privatizzazione son…
Wykorzystanie antagonistycznych właściwości Bacillus subtilis wobec Rhizoctonia solani
2017
The deubiquitinase USP11 is a versatile and conserved regulator of autophagy
2021
Autophagy is a major cellular quality control system responsible for the degradation of proteins and organelles in response to stress and damage to maintain homeostasis. Ubiquitination of autophagy-related proteins or regulatory components is important for the precise control of autophagy pathways. Here, we show that the deubiquitinase ubiquitin-specific protease 11 (USP11) restricts autophagy and that KO of USP11 in mammalian cells results in elevated autophagic flux. We also demonstrate that depletion of the USP11 homolog H34C03.2 in Caenorhabditis elegans triggers hyperactivation of autophagy and protects the animals against human amyloid-β peptide 42 aggregation-induced paralysis. USP11…