Search results for " activity"

showing 10 items of 4540 documents

Synthesis and Antiproliferative Activity of 2,5-bis(3′-Indolyl)pyrroles, Analogues of the Marine Alkaloid Nortopsentin

2013

2,5-bis(3′-Indolyl)pyrroles, analogues of the marine alkaloid nortopsentin, were conveniently prepared through a three step procedure in good overall yields. Derivatives 1a and 1b exhibited concentration-dependent antitumor activity towards a panel of 42 human tumor cell lines with mean IC50 values of 1.54 μM and 0.67 μM, respectively. Investigating human tumor xenografts in an ex-vivo clonogenic assay revealed selective antitumor activity, whereas sensitive tumor models were scattered among various tumor histotypes.

ex-vivo xenograftsIndolesStereochemistryPharmaceutical ScienceMice NudeAntineoplastic AgentsArticleInhibitory Concentration 50MiceCell Line TumorNeoplasmsDrug Discoverybis-indolyl-pyrroles; nortopsentin analogues; marine alkaloids; antitumor; <i>ex-vivo </i>xenograftsIc50 valuesAnimalsHumansnortopsentin analoguePyrrolesClonogenic assayPharmacology Toxicology and Pharmaceutics (miscellaneous)lcsh:QH301-705.5Tumor Stem Cell AssayMice nudeantitumorAntitumor activityDose-Response Relationship DrugChemistryAlkaloidbis-indolyl-pyrroles; nortopsentin analogues; marine alkaloids; antitumor; ex-vivo xenograftsImidazolesTumor Stem Cell AssaySettore CHIM/08 - Chimica FarmaceuticaXenograft Model Antitumor Assaysbis-indolyl-pyrrolemarine alkaloidHuman tumornortopsentin analogueslcsh:Biology (General)Cell culturebis-indolyl-pyrrolesmarine alkaloidsMarine Drugs
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Lipas data 04/2023

2023

This data includes all sport facilities in Lipas database on 23.4.2023 and basic attribute information about the places. The data is classified and each sport facility has its own Lipas ID. The data is provided as Esri Shapefiles (points, routes and areas). Tämä aineisto sisältää kaikki Lipas-tietokannan liikuntapaikat ja aineistotiedot 23.4.2023. Data on luokiteltu, ja jokaiselle liikuntapaikalle on oma Lipas-ID. Data on tarjolla Esri Shapefile -muodossa (pisteet, reitit ja alueet).

exercise areasgeographic informationgeographic information systemspaikkatiedotliikuntatilatliikuntapaikatsports facilitiesliikuntakeskuksetliikuntasuunnitteluliikunta-alueetliikuntapalvelutphysical trainingpaikkatietojärjestelmätsports grounds and physical exercise facilitiesphysical hobbiesexercise centresliikuntaharrastusexercise planningphysical activity services
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Lipas-data 04/2022

2022

Tämä aineisto sisältää kaikki Lipas-tietokannan liikuntapaikat ja aineistotiedot 29.4.2022. Data on luokiteltu, ja jokaiselle liikuntapaikalle on oma Lipas-ID. Data on tarjolla Esri Shapefile -muodossa (pisteet, reitit ja alueet). This data includes all sport facilities in Lipas database on 29.4.2022 and basic attribute information about the places. The data is classified and each sport facility has its own Lipas ID. The data is provided as Esri Shapefiles (points, routes and areas) in Finnish, Swedish and English.

exercise areasgeographic informationgeographic information systemspaikkatiedotliikuntatilatsports facilitiesliikuntapaikatliikuntakeskuksetliikunta-alueetliikuntasuunnitteluphysical trainingliikuntapalvelutpaikkatietojärjestelmätsports grounds and physical exercise facilitiesphysical hobbiesexercise centresliikuntaharrastusexercise planningphysical activity services
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Lipas-data 10/2022

2022

Tämä aineisto sisältää kaikki Lipas-tietokannan liikuntapaikat ja aineistotiedot 20.10.2022. Data on luokiteltu, ja jokaiselle liikuntapaikalle on oma Lipas-ID. Data on tarjolla Esri Shapefile -muodossa (pisteet, reitit ja alueet). This data includes all sport facilities in Lipas database on 20.10.2022 and basic attribute information about the places. The data is classified and each sport facility has its own Lipas ID. The data is provided as Esri Shapefiles (points, routes and areas) in Finnish, Swedish and English.

exercise areasgeographic informationgeographic information systemspaikkatiedotliikuntatilatsports facilitiesliikuntapaikatliikuntakeskuksetliikuntasuunnitteluliikunta-alueetphysical trainingliikuntapalvelutpaikkatietojärjestelmätsports grounds and physical exercise facilitiesphysical hobbiesexercise centresliikuntaharrastusexercise planningphysical activity services
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Using Digital Coaching to Promote Physical Activity to University Students with Low Levels of Physical Activity : A Qualitative Intervention Study

2021

exercise self-efficacyMedical educationliikuntateknologiaopiskelijathyvinvointiteknologiabusiness.industrykuntoliikuntaPhysical activityinterventiotutkimusIntervention studiesCoachingterveyden edistäminendigital coachingmotivationsport technologyuniversity studentsPsychologybusinessfyysinen aktiivisuus
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Different Endurance Exercise Modalities, Different Affective Response: A Within-Subject Study

2021

Affect experienced during an exercise session is supposed to predict future exercise behavior. However, empirical evidence reveals high variability in affective response to different exercise modalities. Thus, the purpose of the present study was to compare acute affective response and its variation during three different endurance exercise modalities: (a) moderate-intensity continuous exercise (MICE), (b) vigorous-intensity continuous exercise (VICE), and (c) high-intensity interval exercise (HIIE). Using the dual-mode theory as a theoretical framework, cognitive and interoceptive factors were considered as potential predictors of in-task affective response. In a within-subject design, 40 …

exerciseaffectvariabilitydual-mode theorywithin-subjectphysical activityPsychologyBF1-990Frontiers in Psychology
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Moving More and Sitting Less as Healthy Lifestyle Behaviors are Protective Factors for Insomnia, Depression, and Anxiety Among Adolescents During the…

2020

Chunping Lu,1,* Xinli Chi,2,* Kaixin Liang,2 Si-Tong Chen,3 Liuyue Huang,2 Tianyou Guo,2 Can Jiao,2 Qian Yu,4 Nicola Veronese,5 Fernanda Cunha Soares,6 Igor Grabovac,7 Albert Yeung,8 Liye Zou4 1The Greater Bay Area Institute of Educational Research, Shenzhen University, Shenzhen 518060, People&amp;rsquo;s Republic of China; 2Center for Lifestyle and Mental Health, Shenzhen University, Shenzhen 518060, People&amp;rsquo;s Republic of China; 3Institute for Health and Sport, Victoria University, Melbourne 8001, Australia; 4Exercise and Mental Health Laboratory, Shenzhen University, Shenzhen 518060, People&amp;rsquo;s Republic of China; 5Geriatric Unit, Department of Internal Medicine and Geriat…

exercisebusiness.industryphysical activityContext (language use)Mental healthOddsPatient Health QuestionnairePsychiatry and Mental healthPsychology Research and Behavior Managementsedentary behaviormental disordersInsomniamedicineAnxietymedicine.symptomRisk factorsleepbusinessGeneral PsychologyDepression (differential diagnoses)mental healthClinical psychologyOriginal ResearchPsychology Research and Behavior Management
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Effects of physical activity, specific exercise and traumatic brain injury on motor abilities : theoretical and pragmatic assessment

2010

exercisekuntoliikuntaadultphysical activitytestitkehonhallintakeski-ikäisetaivovammatmotor abilitybrain injuriesmotor performancemiddle agedsportsliikuntaharrastusfyysinen aktiivisuusaikuisetmotoriikka
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Body Image in 13-17 Years Old Adolescents: Gender and Physical Activity Effects

2013

Σκοπός της παρούσας έρευνας, ήταν να εξετάσει πώς διαφοροποιείται η εικόνα του σώματος και η ικανοποίηση της από αυτήν ανάλογα με το φύλο και την ηλικία, αλλά και πώς συνδέεται με τη φυσική δραστηριότητα και το Δείκτη Μάζας Σώματος σε εφήβους. Το δείγμα ήταν 496 έφηβοι (226 αγόρια και 270 κορίτσια) ηλικίας 13 έως 17 ετών, μαθητές από τη Β’ Γυμνασίου έως και τη Β’ Λυκείου επαρχιακών πόλεων της Ελλάδας. Τα εργαλεία που χρησιμοποιήθηκαν ήταν η κλίμακα της εικόνας του σώματος (Rand & Wright, 1999) και το ερωτηματολόγιο «Άσκηση κατά τον Ελεύθερο Χρόνο» (Godin & Shephard, 1985). Σύμφωνα με τα αποτελέσματα, τα αγόρια ήταν πιο ικανοποιημένα από την εικόνα του σώματός τους σε σχέση με τα κορίτσια. Η…

exercisephysical activityadolescencepainoindeksi
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The osteogenic potential of physical activity

2022

exercisephysical activitybone metabolismbone healthsport
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