Search results for " adolescent"

showing 10 items of 621 documents

Versatility of the Free Anterolateral Thigh Flap in the Reconstruction of Large Defects of the Weight-Bearing Foot: A Single-Center Experience with 2…

2016

Background  Reconstruction of the weight-bearing surface of the foot represents a challenging task. With very little scope to borrow glabrous tissue from adjacent areas means that achieving a “like for like” reconstruction is rarely possible. In this setting, alternative approaches need to be considered. In this article we present our experience with various differing designs of the anterolateral thigh flap (ALT) in the reconstruction of 20 large defects of the weight-bearing sole. Methods  Twenty patients with complex soft tissue defects of the weight-bearing sole underwent reconstruction over a 5-year period. Five cases were complicated by osteomyelitis resulting in significant calcaneal …

AdultMalemedicine.medical_specialtyFoot InjurieSoft Tissue InjuriesAdolescent030230 surgeryThighSingle Centermedicine.disease_causeFree Tissue FlapsWeight-bearinganterolateral thigh perforator flapWeight-Bearing03 medical and health sciencesYoung Adult0302 clinical medicinemedicineReconstructive Surgical ProcedureHumansReconstructive Surgical ProceduresFibulaFoot Injuriesanterolateral thigh perforator flap; calcaneal reconstruction; weight-bearing sole reconstruction; Adolescent; Adult; Aged; Female; Foot Injuries; Free Tissue Flaps; Humans; Male; Middle Aged; Recovery of Function; Retrospective Studies; Soft Tissue Injuries; Thigh; Treatment Outcome; Weight-Bearing; Young Adult; Reconstructive Surgical ProceduresFree Tissue FlapAgedRetrospective Studiesbusiness.industryOsteomyelitisSoft tissueRecovery of FunctionMiddle AgedPlastic Surgery Proceduresmedicine.diseaseGaitSurgerySoft Tissue Injuriemedicine.anatomical_structureTreatment OutcomeThigh030220 oncology & carcinogenesisweight-bearing sole reconstructionSurgeryFemaleFoot Injurybusinesscalcaneal reconstructionJournal of reconstructive microsurgery
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Modified fixation free plug technique using a new 3D multilamellar implant for inguinal hernia repair: a retrospective study of a single operator cas…

2013

Aim: Implant fixation, mesh shrinkage and poor quality of tissue ingrowth are unresolved issues in modern hernia repair. Many complications reported in the literature such as bleeding, nerve entrapment, hematoma, pain, discomfort, and testicular complications, are considered to be a direct results of implant fixation. This article describes the outcomes of a procedure carried out using a handcrafted implant that addresses the issues consequent to point fixation. Methods: This was a retrospective study on the short, medium and long-term results of placing a-modified, fixation free three-dimensional polypropylene implant in 61 patients who underwent inguinal hernia repair using a novel delive…

AdultMalemedicine.medical_specialtyHerniaAdolescentmedicine.medical_treatmentprostheses and implantOperative TimeHernia InguinalPolypropylenesProsthesis DesignFixation (surgical)HematomaPostoperative ComplicationsRetrospective Studiemedicineprosthesis fixation.HumansHerniaHerniorrhaphyAgedRetrospective StudiesAged 80 and overPain Postoperativebusiness.industryHernia; Herniorrhaphy; Inguinal; Prostheses and implants; Prosthesis fixation; Adolescent; Adult; Aged; Aged 80 and over; Female; Hernia Inguinal; Herniorrhaphy; Humans; Male; Middle Aged; Operative Time; Pain Postoperative; Polypropylenes; Postoperative Complications; Prosthesis Design; Retrospective Studies; Treatment Outcome; Surgical Mesh; Surgery; Medicine (all)Medicine (all)Chronic painMiddle AgedSurgical Meshmedicine.diseaseHernia repairSurgeryInguinal herniaSettore MED/18 - Chirurgia GeneraleSurgical meshTreatment OutcomeinguinalSurgeryFemaleImplantPostoperative ComplicationbusinessProsthesis fixationPolypropylenehernia; inguinal; herniorrhaphy; prostheses and implants; prosthesis fixation.HumanHernia : the journal of hernias and abdominal wall surgery
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Inflammatory Bowel Disease Phenotype as Risk Factor for Cancer in a Prospective Multicentre Nested Case-Control IG-IBD Study

2016

Background and Aims: Cancer risk in inflammatory bowel disease [IBD] is still debated. In a prospective, multicentre, nested case-control study, we aimed to characterise incident cases of cancer in IBD. The role of immunomodulators vs clinical characteristics of IBD as risk factors for cancer was also investigated. Materials and Methods: From January 2012 to December 2014, each IBD patient with incident cancer was matched with two IBD patients without cancer for: IBD type, gender, and age. Risk factors were assessed by multivariate regression analysis. Results: IBD patients considered numbered 44619: 21953 Crohn’s disease \[CD], 22666 ulcerative colitis [UC]. Cancer occurred in 174 patients…

AdultMalemedicine.medical_specialtyPancolitisAdolescentColorectal cancerphenotypeSettore MED/12 - GASTROENTEROLOGIAcancer riskInflammatory bowel disease; cancer risk; phenotype; Adolescent; Adult; Aged; Aged 80 and over; Case-Control Studies; Female; Follow-Up Studies; Humans; Immunologic Factors; Incidence; Inflammatory Bowel Diseases; Logistic Models; Male; Middle Aged; Multivariate Analysis; Neoplasms; Prospective Studies; Risk Factors; Young Adult; PhenotypeGastroenterologyInflammatory bowel diseaseInflammatory bowel disease03 medical and health sciencesYoung Adult0302 clinical medicineRisk FactorsInternal medicineNeoplasms80 and overmedicineHumansImmunologic FactorsProspective StudiesRisk factorProspective cohort studyAgedAged 80 and overbusiness.industryIncidenceSettore MED/09 - MEDICINA INTERNAGastroenterologyCancerGeneral MedicineMiddle Agedmedicine.diseaseInflammatory Bowel DiseasesUlcerative colitisLogistic Models030220 oncology & carcinogenesisCase-Control StudiesNested case-control studyMultivariate Analysis030211 gastroenterology & hepatologyFemalemedicine.symptombusinessInflammatory bowel disease; cancer risk; phenotypeFollow-Up Studies
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RhinAsthma patient perspective: a short daily asthma and rhinitis QoL assessment.

2012

Background The present study aimed to develop a short validated patient-completed questionnaire, the RhinAsthma Patient Perspective (RAPP), to assess the health-related quality of life (HRQoL) in patients with asthma and comorbid allergic rhinitis in clinical practice. Methods A provisional RAPP questionnaire was formed from candidate items identified through retrospective analysis of 333 RHINASTHMA questionnaires. This was then tested on 150 asthma patients with allergic rhinitis. Results Psychometric analyses identified eight items fitting a unidimensional model to form RAPP. Internal consistency (Cronbach's alpha coefficient > 0.8) and agreement with RHINASTHMA (r = −0.31, P = 0.0001) we…

AdultMalemedicine.medical_specialtyRhinitis Allergic PerennialPsychometricsAdolescentPsychometricsVisual analogue scaleassessmentConcordanceImmunologyPopulationSettore MED/10 - Malattie Dell'Apparato RespiratoriorhinitisAllergicCronbach's alphaQuality of lifeSurveys and Questionnaires80 and overmedicineSurveys and QuestionnaireImmunology and AllergyHumansdaily practiceeducationAsthmaAgedAged 80 and overeducation.field_of_studybusiness.industryassessment; asthma; daily practice; quality of life; rhinitis; Adolescent; Adult; Aged; Aged 80 and over; Asthma; Female; Humans; Male; Middle Aged; Psychometrics; Rhinitis Allergic; Rhinitis Allergic Perennial; Quality of Life; Surveys and Questionnaires; Immunology and Allergy; ImmunologyMiddle Agedmedicine.diseasePerennialRhinitis AllergichumanitiesAsthmarhinitiConvergent validityassessment; asthma; daily practice; quality of life; rhinitisPhysical therapyQuality of LifeFemalebusinessPsychometricHumanAllergy
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The epidemiology of mumps in Italy.

2008

In Italy, although vaccination has been recommended for a number of years, vaccination coverage for mumps is still sub-optimal. The objective of the present study was to evaluate the seroprevalence of mumps antibodies in the Italian population, stratified by age, gender and geographical area. The proportion of individuals positive for mumps antibodies remained stable in the age classes 0–11 months and 1 year (25.4% and 30.8%, respectively) and showed a continuous increase after the second year of life. The percentage of susceptible individuals was higher than 20% in persons 2–14 years of age and exceeded 10% in persons 15–39 years of age. No statistically significant differences were observ…

AdultMalemedicine.medical_specialtySettore MED/07 - Microbiologia E Microbiologia ClinicaAdolescentDatabases FactualMumps; Seroprevalence; Vaccination; Adolescent; Adult; Age Factors; Child; Child Preschool; Databases Factual; Disease Outbreaks; Female; Humans; Immunoglobulin G; Infant; Italy; Male; Middle Aged; Mumps; Registries; Seroepidemiologic Studiesmumps; seroprevalence; vaccinationSerologyDisease OutbreaksDatabasesSeroepidemiologic StudiesEpidemiologymedicineSeroprevalenceHumansRegistriesPreschoolChildMumpsFactualGeneral VeterinaryGeneral Immunology and Microbiologyseroprevalencebusiness.industryPublic Health Environmental and Occupational HealthAge FactorsInfantMiddle AgedvaccinationItalian populationVirologyVaccinationMumps Seroprevalence VaccinationInfectious DiseasesItalyVaccination coverageChild PreschoolImmunoglobulin GMolecular MedicineFemaleViral diseasebusinessDemographyVaccine
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Patient and physician views on the quality of care in inflammatory bowel disease: Results from SOLUTION-1, a prospective IG-IBD study

2014

Remarkable differences in quality of care (QoC) might be observed in different countries, affecting quality of life of inflammatory bowel disease (IBD) patients. The aim of this study was to assess patient and physician perceptions of the QoC in Italy.A multicentre observational study on the quality of care in IBD (SOLUTION-1) was conducted in 36 IG-IBD (Italian Group for Inflammatory Bowel Disease) centres in Italy. The QUOTE-IBD (Quality of Care Through the Patient's Eyes) questionnaire was administered to IBD patients and to the attending physicians. The Quality Impact (QI) score summarises the QUOTE-IBD questionnaire, and a QI9 is considered satisfactory.Nine-hundred-ninety-two patients…

AdultMalemedicine.medical_specialtyquality impact score; quote-ibd; quality of careAdolescentAttitude of Health PersonnelQuality impact score; Quality of care; QUOTE-IBD; Adolescent; Adult; Aged; Aged 80 and over; Attitude of Health Personnel; Clinical Competence; Continuity of Patient Care; Female; Humans; Inflammatory Bowel Diseases; Italy; Male; Middle Aged; Patient Education as Topic; Patient Satisfaction; Professional Autonomy; Prospective Studies; Surveys and Questionnaires; Young Adult; Quality of Health Care; Medicine (all)Quality impact scoreGastroenterologyInflammatory bowel diseaseYoung AdultQUOTE-IBDPatient Education as TopicSurveys and QuestionnairesInternal medicineHealth care80 and overPhysician perceptionHumansMedicineProfessional AutonomyPharmaceutical SolutionsProspective StudiesQuality of careCompetence (human resources)AgedQuality of Health CareAged 80 and overbusiness.industryMedicine (all)Quality of careGastroenterologyQuality impact score; Quality of care; QUOTE-IBD; GastroenterologyGeneral MedicineContinuity of Patient CareMiddle AgedInflammatory Bowel Diseasesmedicine.diseasedigestive system diseasesItalyPatient SatisfactionFamily medicineFemaleContinuity of careObservational studyClinical CompetencebusinessJournal of Crohn's and Colitis
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Immunogenicity and safety of human papillomavirus-16/18 AS04-adjuvanted vaccine administered according to an alternative dosing schedule compared wit…

2011

BACKGROUND: The human papillomavirus (HPV)-16/18 AS04-adjuvanted vaccine is immunogenic, has a clinically acceptable safety profile, and prevents incident and persistent HPV-16/18 infection and cervical precancerous lesions. This study (NCT00552279) evaluated the vaccine when administered according to an alternative dosing schedule (0-1-12 months) compared with the standard dosing schedule (0-1-6 months). METHODS: The study was of randomized open design and was conducted at multiple centers in Europe. Healthy women aged 15 to 25 years were randomized (1:1) to receive HPV-16/18 vaccine according to the standard schedule at months 0, 1, and 6 (n = 401) or an alternative schedule at months 0, …

AdultMicrobiology (medical)medicine.medical_specialtyScheduleAdolescentImmunization SecondaryEnzyme-Linked Immunosorbent AssayAntibodies Virallaw.inventionYoung AdultAdjuvants ImmunologicRandomized controlled triallawInternal medicinemedicineHumansPapillomavirus VaccinesDosingHuman papillomavirusYoung adultbusiness.industryImmunogenicityhuman papillomavirus human papillomavirus vaccines adolescent immunology alternative dosing scheduleVaccinationvirus diseasesSettore MED/40 - Ginecologia E Ostetriciafemale genital diseases and pregnancy complicationsEuropeSafety profileInfectious DiseasesImmunizationPediatrics Perinatology and Child HealthImmunologyFemalebusiness
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Stress, pain, and work affiliation are strongly associated with health-related quality of life in parents of 14-15-year-old adolescents

2022

Abstract Background For many adults, their role as a parent is a vital part of their lives. This role is likely to be associated with a parent’s health-related quality of life (HRQOL). The aim of this study was to explore the associations between gender, demographic and psychosocial variables, pain, and HRQOL in parents of 14–15-year-old adolescents. Methods This was a cross-sectional study that included 561 parents. Data on demographic, psychosocial variables and pain were collected using validated instruments. HRQOL was assessed using the RAND-36. Data were analysed using univariate and hierarchical multiple linear regression analyses. Results Four hundred and thirty-six (78%) mothers and…

AdultParentsAdolescentHealth-related quality of lifeComputer applications to medicine. Medical informaticsR858-859.7PainStressAdolescentsHealth-related life qualitySurveys and QuestionnairesStress (linguistics)PainsHumansHealth related quality of lifeVDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin sosialmedisin: 801ResearchPublic Health Environmental and Occupational HealthWork affiliationWork affliationsGeneral MedicineMiddle AgedhumanitiesCross-Sectional StudiesParents of adolescentsWork (electrical)Quality of LifeFemaleChronic PainPsychologyClinical psychology
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Whooping cough, twenty years from acellular vaccines introduction

2015

Clinical pertussis resulting from infection with B. pertussis is a significant medical and public health problem, despite the huge success of vaccination that has greatly reduced its incidence. The whole cell vaccine had an undeniable success over the last 50 years, but its acceptance was strongly inhibited by fear, only partially justified, of severe side effects, but also, in the Western world, by the difficulty to enter in combination with other vaccines: today multi-vaccine formulations are essential to maintain a high vaccination coverage. The advent of acellular vaccines was greeted with enthusiasm by the public health world: in the Nineties, several controlled vaccine trials were car…

AdultPertussis VaccineAcellular vaccinesSecondaryVaccinesSettore MED/07 - Microbiologia E Microbiologia ClinicaTime FactorsAdolescentWhooping CoughMedicine (all)VaccinationImmunization SecondaryVaccine trialInfantVaccines AcellularImmunoprotectionPertussiPertussisAcellularItalyHumansAcellular vaccines; Immunoprotection; Pertussis; Vaccine trials; Adolescent; Adult; Humans; Immunization Secondary; Infant; Italy; Pertussis Vaccine; Time Factors; Vaccination; Vaccines Acellular; Whooping CoughImmunizationVaccine trialsAcellular vaccine
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Long-term evaluation of quality of life and gastrointestinal well-being after segmental colo-rectal resection for deep infiltrating endometriosis (EN…

2019

Purposes: The primary objective is to assess the long-term quality of life (QoL) and gastrointestinal well-being in patients with endometriosis (DIE) who underwent segmental resection (SR), through specific questionnaires focused on endometriosis and specific gastrointestinal evaluation. The secondary objectives are represented by the evaluation of peri-operative and post-operative outcomes of the procedure. Methods: This observational cohort study ENDO-RESECT (ClinicalTrials.gov ID: NCT03824054) reports all clinical data about women who underwent SR for DIE between October 2005 and November 2017. In the part of the study dedicated to the QoL assessment, the questionnaires adopted were the …

AdultQuality of lifemedicine.medical_specialtyAbdominal painConstipationAdolescentGastrointestinal DiseasesEndometriosisEndometriosisSegmental colo-rectal resectionHospital Anxiety and Depression ScaleGastrointestinal symptomsCohort StudiesYoung AdultPostoperative ComplicationsQuality of lifePregnancySurveys and QuestionnairesInternal medicineGastrointestinal symptommedicineHumansDeep infiltrating endometriosis; Gastrointestinal symptoms; Intestinal endometriosis; Personalized medicine; Quality of life; Segmental colo-rectal resection; Adolescent; Adult; Cohort Studies; Colorectal Neoplasms; Endometriosis; Female; Gastrointestinal Diseases; Humans; Middle Aged; Postoperative Complications; Pregnancy; Quality of Life; Surveys and Questionnaires; Treatment Outcome; Young Adultbusiness.industryIntestinal endometriosiObstetrics and GynecologyGeneral MedicineMiddle Agedmedicine.diseasePersonalized medicineDeep infiltrating endometriosiTreatment OutcomeSettore MED/40 - GINECOLOGIA E OSTETRICIADeep infiltrating endometriosisDeep infiltrating endometriosis; Intestinal endometriosis; Segmental colo-rectal resection; Quality of life; Gastrointestinal symptoms; Personalized medicineDefecationFemaleIntestinal endometriosisSegmental resectionmedicine.symptomColorectal NeoplasmsbusinessCohort study
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