Search results for " adolescent"

showing 10 items of 621 documents

Does parental expressed emotion moderate genetic effects in ADHD? An exploration using a genome wide association scan.

2008

Contains fulltext : 70497.pdf (Publisher’s version ) (Closed access) Studies of gene x environment (G x E) interaction in ADHD have previously focused on known risk genes for ADHD and environmentally mediated biological risk. Here we use G x E analysis in the context of a genome-wide association scan to identify novel genes whose effects on ADHD symptoms and comorbid conduct disorder are moderated by high maternal expressed emotion (EE). SNPs (600,000) were genotyped in 958 ADHD proband-parent trios. After applying data cleaning procedures we examined 429,981 autosomal SNPs in 909 family trios. ADHD symptom severity and comorbid conduct disorder was measured using the Parental Account of Ch…

MaleParentsCandidate geneGenetics and epigenetic pathways of disease [NCMLS 6]Medizin2804 Cellular and Molecular NeuroscienceHostilityNeuroinformatics [DCN 3]2738 Psychiatry and Mental Health0302 clinical medicineGene FrequencyPerception and Action [DCN 1]Gene–environment interactionParent-Child RelationsChildGenetics (clinical)NeuregulinsbiologySLC1A1Intracellular Signaling Peptides and Proteins10058 Department of Child and Adolescent PsychiatryPsychiatry and Mental healthExpressed EmotionExcitatory Amino Acid Transporter 3Conduct disorderChild PreschoolFemalemedicine.symptomFunctional Neurogenomics [DCN 2]Clinical psychologyGenetic Markers2716 Genetics (clinical)AdolescentQuantitative Trait Loci610 Medicine & healthSingle-nucleotide polymorphismContext (language use)Mental health [NCEBP 9]Polymorphism Single NucleotideGenomic disorders and inherited multi-system disorders [IGMD 3]Interviews as Topic03 medical and health sciencesCellular and Molecular NeuroscienceCognitive neurosciences [UMCN 3.2]mental disordersmedicineExpressed emotionHumansddc:610Medizinische Fakultät » Universitätsklinikum Essen » LVR-Klinikum Essen » Klinik für Psychiatrie Psychosomatik und Psychotherapie des Kindes- und JugendaltersAllelesProbabilityModels Geneticbusiness.industryGenome Humanmedicine.disease030227 psychiatryGenetic defects of metabolism [UMCN 5.1]Attention Deficit Disorder with Hyperactivitybiology.proteinbusiness030217 neurology & neurosurgeryGenome-Wide Association Study
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Differences in beliefs and home environments regarding energy balance behaviors according to parental education and ethnicity among schoolchildren in…

2014

Background To explore differences in personal and home environmental factors that are regarded as determinants of energy balance-related behaviors (EBRBs) according to parental education and ethnic background among 10–12 year old schoolchildren across Europe. Methods A school-based survey among 10–12 year olds was conducted in eight countries across Europe. A range of personal and home environment variables relevant for soft drink consumption, daily breakfast, sport participation and TV time was assessed by means of child report. Personal factors included attitude, health beliefs, and preference/liking. Home environment factors included parental subjective norm, modeling, support, practices…

MaleParentsGerontologyHealth Knowledge Attitudes PracticeBeliefsCross-sectional studyHealth BehaviorEthnic groupYOUNG-PEOPLECarbonated Beveragesbeliefs energy-balance behaviors ethnicity home environments parental education schoolchildrenMedicine and Health SciencesEthnicityMedicineChildCONSTRUCT-VALIDITY4. EducationPeer reviewEuropeSPORTS PARTICIPATIONVDP::Medisinske Fag: 700::Helsefag: 800Educational StatusFemaleTelevisionLIFE-STYLETEST-RETEST RELIABILITYCHILDHOOD OBESITYEnergy-balance behaviorsSportsResearch Articlemedicine.medical_specialtyParental educationSchoolchildrenChildhood obesityHumansSCHOOL-BASED INTERVENTIONSObesityExerciseDUTCH ADOLESCENTSBreakfastHome environmentsConsumption (economics)business.industryPublic healthPublic Health Environmental and Occupational HealthConstruct validitymedicine.diseaseCross-Sectional StudiesPHYSICAL-ACTIVITYWEIGHT STATUSBiostatisticsEnergy IntakebusinessDemography
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Psychological adjustment of Spanish adolescents and their parents during COVID- 19 lockdown: A mixed method approach

2021

Previous literature on the psychological impact of COVID-19 has shown a direct relationship between family conflicts and psychological distress among parents and their children during the domestic lockdown and social isolation; but there are also opportunities to enhance family bonding, encourage collective problem-solving and improve personal relationships. This study aimed to explore psychological adjustment processes of Spanish adolescents and their parents during the first month of lockdown by analyzing their narratives, perceived outcomes, protection and risk factors. A total of 142 people agreed to participate in this study. Of all participants, 61 were adolescents (M = 13.57; SD = 1.…

MaleParentsViral DiseasesEpidemiologyEmotionsSocial SciencesPsychological DistressAdolescentsFamiliesMedical Conditions0302 clinical medicineMixed approachSociologySurveys and QuestionnairesAdaptation PsychologicalPsicología del adolescenteMedicine and Health SciencesPsychologyHuman FamiliesSocial isolationChildrenmedia_commonMultidisciplinaryQ05 social sciencesRMental HealthInfectious DiseasesSocial IsolationFeelingMedicineFemalemedicine.symptomPsychologyResearch ArticleClinical psychologyAdolescentPsychological AdjustmentSocial PsychologyCoronavirus disease 2019 (COVID-19)Sciencemedia_common.quotation_subjectEmotional Adjustment050105 experimental psychology03 medical and health sciencesSocial supportEpidemiamedicineHumans0501 psychology and cognitive sciencesNarrativeBiology and Life SciencesPsychological distressCOVID-19Covid 19Mental healthPsicologíaSpainAge GroupsMedical Risk FactorsPeople and PlacesPopulation GroupingsStress Psychological030217 neurology & neurosurgery
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Socioeconomic inequalities in adolescent smoking across 35 countries: A multilevel analysis of the role of family, school and peers

2015

BACKGROUND: Tobacco-related heath inequalities are a major public health concern, with smoking being more prevalent among lower socioeconomic groups. The aim of this study is to investigate the mechanisms leading to socioeconomic inequalities in smoking among 15-year-old adolescents by examining the mediating role of psychosocial factors in the peer group, family and school environment.METHODS: Data were derived from the international WHO-collaborative 'Health Behaviour in School-aged Children (HBSC)' study 2005/2006, including 52 907 15-year-old students from 35 European and North American countries. Socioeconomic position was measured by the Family Affluence Scale. Multilevel logistic reg…

MaleParentssocioeconomic groupsPediatricsmedicine.medical_specialtyInequalityAdolescentmedia_common.quotation_subjecteducationHealth Behaviortobacco useAcademic achievementPeer Groupschool environmentAdolescent; Adolescent Behavior; Europe; Family; Female; Health Behavior; Humans; Male; North America; Parents; Smoking; Socioeconomic Factors; Students; Health Status Disparities; Peer Group; Schools; Public Health Environmental and Occupational HealthmedicineHumansFamilyadolescentsStudentsSocioeconomic statusmedia_commonSchoolssocioeconomic inequalitiesPublic healthMultilevel modelSmokingEnvironmental and Occupational HealthPublic Health Environmental and Occupational HealthPeer groupta3142Health Status DisparitiesEuropeSocioeconomic FactorsAdolescent BehaviorScale (social sciences)North AmericaFemalePublic HealthPsychologyPsychosocialDemography
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Impact of sublingual immunotherapy on seasonal asthma and skin reactivity in children allergic to Parietaria pollen treated with inhaled fluticasone …

2003

Immunotherapy is a recognized treatment for allergic respiratory diseases.

MaleParietaria; Androstadienes; Skin; Double-Blind Method; Combined Modality Therapy; Humans; Asthma; Child; Desensitization Immunologic; Anti-Allergic Agents; Plant Proteins; Pollen; Rhinitis Allergic Seasonal; Allergens; Treatment Outcome; Administration Inhalation; Adolescent; Administration Sublingual; Male; FemaleParietaria pollenAdolescentAdministration Sublingualsublingual immunotherapylate skin responsechildrenDouble-Blind Methodchildren; early skin response; fluticasone; late skin response; Parietaria pollen; sublingual immunotherapy; visual analog scoreAdministration InhalationChildSkinAndrostadieneAllergenearly skin responsefluticasonePlant ProteinRhinitis Allergic SeasonalCombined Modality TherapyAsthmaAnti-Allergic Agentvisual analog scoreParietariaTreatment OutcomeDesensitization ImmunologicPollenFemaleHuman
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Scalp eschar and neck lymphadenopathy caused by Rickettsia massiliae

2013

To the Editor: Scalp eschar and neck lymphadenopathy is a common clinical entity that most frequently affects women and children during spring and fall. It is usually caused by Rickettsia slovaca and R. raoultii. Typical clinical signs are a scalp lesion at the tick bite site and regional, often painful, lymphadenopathy. Acute disease can be followed by residual alopecia at the bite site (1,2). Two designations have been proposed for this syndrome: tick-borne lymphadenopathy and Dermacentor-borne necrosis-erythema-lymphadenopathy (both have been associated with R. slovaca); however, the most generic and all-inclusive term is scalp eschar and neck lymphadenopathy. R. massiliae belongs to the…

MalePathologyLetterEpidemiologylcsh:MedicineSerologyMedicineRickettsiaRickettsia massiliaebacteriafeverbiologyRickettsia InfectiontickInfectious Diseasesmedicine.anatomical_structuremedicine.symptomDermacentorHumanDNA BacterialMicrobiology (medical)medicine.medical_specialtyAdolescentSettore MED/17 - Malattie InfettiveMolecular Sequence DataInfectious DiseaseEscharTicklcsh:Infectious and parasitic diseasesCicatrixBacterial Typing Techniquelymphadenopathylcsh:RC109-216Rickettsia; Rickettsia massiliae; bacteria; eschar; fever; lymphadenopathy; scalp eschar and neck lymphadenopathy; tick; Adolescent; Alopecia; Animals; Bacterial Typing Techniques; Base Sequence; Cicatrix; DNA Bacterial; Dermacentor; Humans; Lymphatic Diseases; Male; Molecular Sequence Data; Rickettsia; Rickettsia Infections; Scalp; Microbiology (medical); Infectious Diseases; EpidemiologyLetters to the EditorDermacentorRickettsia massiliaeScalpScalp EscharBase Sequencebusiness.industryAnimallcsh:RRickettsia massiliae; Scalp Eschar; LymphadenopathyAlopeciascalp eschar and neck lymphadenopathybiology.organism_classificationSpotted feverRickettsiaScalpLymphatic Diseasebusinesseschar
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ROC-king onwards: intraepithelial lymphocyte counts, distribution & role in coeliac disease mucosal interpretation

2017

ObjectivesCounting intraepithelial lymphocytes (IEL) is central to the histological diagnosis of coeliac disease (CD), but no definitive ‘normal’ IEL range has ever been published. In this multicentre study, receiver operating characteristic (ROC) curve analysis was used to determine the optimal cut-off between normal and CD (Marsh III lesion) duodenal mucosa, based on IEL counts on >400 mucosal biopsy specimens.DesignThe study was designed at the International Meeting on Digestive Pathology, Bucharest 2015. Investigators from 19 centres, eight countries of three continents, recruited 198 patients with Marsh III histology and 203 controls and used one agreed protocol to count IEL/100 ent…

MalePathologySettore MED/09 - Medicina Interna2312ROC-curve analysiBiopsyCoeliac diseaseSerology0302 clinical medicineintraepithelial lymphocytesDiagnosis80 and overROC-curve analysis; coeliac disease; intraepithelial lymphocytes1506LymphocytesIntestinal MucosaChild1507medicine.diagnostic_testArea under the curveGastroenterologyhemic and immune systemsMiddle AgedPrognosis030220 oncology & carcinogenesis030211 gastroenterology & hepatologyFemalemedicine.symptomtissuesAdultmedicine.medical_specialtyAdolescentchemical and pharmacologic phenomenaBiologydigestive systemLesion03 medical and health sciencesBiopsymedicineHumansLymphocyte CountPreschoolAgedReceiver operating characteristicInfantHistologymedicine.diseaseNewbornROC-curve analysis; coeliac disease; intraepithelial lymphocytes; Adolescent; Adult; Aged; Aged 80 and over; Biopsy; Case-Control Studies; Celiac Disease; Child; Child Preschool; Diagnosis Differential; Female; Humans; Infant; Infant Newborn; Intestinal Mucosa; Lymphocyte Count; Lymphocytes; Male; Middle Aged; Prognosis; ROC Curve; GastroenterologyCeliac DiseaseROC CurveCase-Control StudiesDifferentialIntraepithelial lymphocyteROC-curve analysiscoeliac disease
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A fitness index model for Italian adolescents living in Southern Italy. The ASSO project

2016

BACKGROUND: Strong relations between physical fitness and health in adolescents have been established in the last decades. The main objectives of the present investigation were to assess major physical fitness components in a sample of Italian school adolescents, comparing them with international data, and providing a Fitness Index model derived from percentile cut-off values of five considered physical fitness components. METHODS: A total of 644 school pupils (15.9�1.1 years; M: N.=399; F: N.=245) were tested using the ASSO-Fitness Test Battery (FTB), a tool developed within the Adolescents and Surveillance System for the Obesity prevention project, which included the handgrip, standing br…

MalePediatric ObesitySchoolsAdolescentHand Strengthschoolexercise testPhysical fitness - Adolescent - Pediatric obesity - Prevention and controlbody massfitnesshealth surveyBody Mass IndexfemaleItalyPhysical FitnessPopulation SurveillancephysiologyExercise TestHumansFemalehumanprocedures
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Clinical features and follow-up in patients with 22q11.2 deletion syndrome

2014

Objective To investigate the clinical manifestations at diagnosis and during follow-up in patients with 22q11.2 deletion syndrome to better define the natural history of the disease. Study design A retrospective and prospective multicenter study was conducted with 228 patients in the context of the Italian Network for Primary Immunodeficiencies. Clinical diagnosis was confirmed by cytogenetic or molecular analysis. Results The cohort consisted of 112 males and 116 females; median age at diagnosis was 4 months (range 0 to 36 years 10 months). The diagnosis was made before 2 years of age in 71% of patients, predominantly related to the presence of heart anomalies and neonatal hypocalcemia. In…

MalePediatrics22q11.2 deletionDelayed DiagnosisTime FactorsChromosomes Human Pair 22Developmental Disabilitiesdigeorge syndromeSex FactorSeverity of Illness IndexRetrospective StudieDiGeorge syndromeEarly DiagnosiAge FactorProspective StudiesNeonatal hypocalcemiaProspective cohort studyChildmedicine.diagnostic_testDelayed Diagnosi22q11.2 deletion; Primary immune disordersAge Factorsdel 22qMIMAbnormalities Multiple; Adolescent; Adult; Age Factors; Child; Child Preschool; Chromosomes Human Pair 22; Delayed Diagnosis; Developmental Disabilities; DiGeorge Syndrome; Early Diagnosis; Female; Follow-Up Studies; Genetic Testing; Humans; Infant; Infant Newborn; Male; Monitoring Physiologic; Prospective Studies; Retrospective Studies; Risk Assessment; Severity of Illness Index; Sex Factors; Time Factors; Young Adult; Disease ProgressionChild PreschoolCohortDisease ProgressionPrimary immune disordersFemaleAbnormalitiesMultipleAbnormalities Multiple; Adolescent; Adult; Age Factors; Child; Child Preschool; Chromosomes Human Pair 22; Delayed Diagnosis; Developmental Disabilities; DiGeorge Syndrome; Early Diagnosis; Female; Follow-Up Studies; Genetic Testing; Humans; Infant; Infant Newborn; Male; Monitoring Physiologic; Prospective Studies; Retrospective Studies; Risk Assessment; Severity of Illness Index; Sex Factors; Time Factors; Young Adult; Disease Progression; Pediatrics Perinatology and Child HealthHumanAdultmedicine.medical_specialtyTime FactorAdolescentMonitoringDevelopmental DisabilitieItalian Association of Pediatric Haematology and OncologyContext (language use)Risk AssessmentChromosomesFollow-Up StudieYoung AdultSex FactorsSeverity of illnessmedicineDiGeorge SyndromeHumansAbnormalities MultipleGenetic Testing22q11DS; 22q11.2 deletion syndrome; AIEOP; Italian Association of Pediatric Haematology and Oncology; MIM; Mendelian Inheritance in Man22q11DSPreschoolPhysiologicdigeorge syndrome; del 22qGenetic testingMonitoring PhysiologicRetrospective StudiesSettore MED/38 - Pediatria Generale e Specialisticabusiness.industryMendelian Inheritance in ManInfant NewbornInfantRetrospective cohort studymedicine.diseaseNewbornAIEOPProspective StudieEarly Diagnosis22q11.2 deletion syndromePediatrics Perinatology and Child HealthPair 22businessFollow-Up Studies
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Adherence to growth hormone (GH) therapy in naïve to treatment GH-deficient children: data of the Italian Cohort from the Easypod Connect Observation…

2019

Background: With the use of non-objective measurement, adherence to growth hormone (GH) therapy has been reported suboptimal in a large proportion of patients, and poor adherence has been shown to affect short-term growth response in patients receiving GH treatment. Objective: The Easypod™ electronic device allows objective measurement of adherence. In this study, we report 3-year prospective adherence data of the Italian cohort of naïve GH deficient (GHD) children extrapolated from the Easypod Connect Observational Study (ECOS) database. Patients and methods: Seventy-three GHD children naïve to GH treatment were included in the analysis. 22 Italian centers participated in the study. Result…

MalePediatricsDatabases FactualChildren; ECOS; GHD; Growth hormone; Short statureEndocrinology Diabetes and MetabolismChildren; ECOS; GHD; Growth hormone; Short stature;Children; ECOS; GHD; Growth hormone; Short stature; Adolescent; Child; Cohort Studies; Databases Factual; Dwarfism Pituitary; Female; Growth Disorders; Human Growth Hormone; Humans; Italy; Male; Medication Adherence; Telemedicine; Medical Records Systems Computerized; Wearable Electronic DevicesGrowth hormoneCohort Studies0302 clinical medicineEndocrinologyChildChildrenGrowth DisordersHuman Growth HormoneChildren ECOS GHD Growth hormone Short statureObjective measurementSettore MED/38TelemedicineItaly030220 oncology & carcinogenesisCohortFemaleOriginal ArticleMedical Records Systemsmedicine.symptomCohort studymedicine.medical_specialtyAdolescentMedical Records Systems ComputerizedDwarfism030209 endocrinology & metabolismShort statureMedication AdherenceDatabasesWearable Electronic Devices03 medical and health sciencesmedicineHumansIn patientDwarfism PituitaryGrowth hormoneFactualbusiness.industryComputerizedShort staturePituitaryGh treatmentECOSObservational studybusinessGHDJournal of Endocrinological Investigation
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