Search results for " algorithm"

Large-Eddy Simulation of Flow and Heat Transfer in Compact Heat Exchangers

1994

LES results are presented for different heat exchanger geometries. Subgrid terms were usually computed by the Smagorinsky model; preliminary comparative results are also given for the ‘dynamic’ subgrid model. The numerical methods used were those implemented in a commercial general-purpose code (CFDS-FLOW3D); they included a finite-volume approach, colocated body-fitted grids, central differencing for the advection terms, the SIMPLEC algorithm, and Crank-Nicolson time stepping. Predictions arc compared with experimental measurements (including local Nu distributions), and with results from a low-Reynolds number k-e model. In most cases, LES was more ‘robust’ and required little more CPU tim…

Analysing the efficiency of wastewater treatment plants: The problem of the definition of desirable outputs and its solution

2020

Abstract Evaluating the efficiency of wastewater treatment plants (WWTPs) is highly relevant to improve their performance from an economic and environmental perspective. The issue is even more critical in countries where WWTPs are benchmarked to regulate water companies and define WWTPs’ economic and environmental objectives. Despite the large number of previous studies on this topic, none has considered that the amount of outputs produced by the WWTPs is restricted by the concentration of pollutants in the effluent. To overcome this limitation, the study’s main objective was to propose a new variant of the Weighted Russell Directional Distance Model (WRDDM) that would solve problems regard…

The German Water Chemical Society: Actual Trends and Fields of Research in the Principle Committee “Basic Research”Representing the principle committ…

2001

CRISPR-Cas12a-Based Detection of SARS-CoV-2 Harboring the E484K Mutation

2021

The novel respiratory virus SARS-CoV-2 is rapidly evolving across the world with the potential of increasing its transmission and the induced disease. Here, we applied the CRISPR-Cas12a system to detect, without the need of sequencing, SARS-CoV-2 genomes harboring the E484K mutation, first identified in the Beta variant and catalogued as an escape mutation. The E484K mutation creates a canonical protospacer adjacent motif for Cas12a recognition in the resulting DNA amplicon, which was exploited to obtain a differential readout. We analyzed a series of fecal samples from hospitalized patients in Valencia (Spain), finding one infection with SARS-CoV-2 harboring the E484K mutation, which was t…

Minimal Absent Words in Rooted and Unrooted Trees

2019

We extend the theory of minimal absent words to (rooted and unrooted) trees, having edges labeled by letters from an alphabet \(\varSigma \) of cardinality \(\sigma \). We show that the set \(\text {MAW}(T)\) of minimal absent words of a rooted (resp. unrooted) tree T with n nodes has cardinality \(O(n\sigma )\) (resp. \(O(n^{2}\sigma )\)), and we show that these bounds are realized. Then, we exhibit algorithms to compute all minimal absent words in a rooted (resp. unrooted) tree in output-sensitive time \(O(n+|\text {MAW}(T)|)\) (resp. \(O(n^{2}+|\text {MAW}(T)|)\) assuming an integer alphabet of size polynomial in n.

Continuous-Variable Instantaneous Quantum Computing is Hard to Sample

2017

Instantaneous quantum computing is a sub-universal quantum complexity class, whose circuits have proven to be hard to simulate classically in the Discrete-Variable (DV) realm. We extend this proof to the Continuous-Variable (CV) domain by using squeezed states and homodyne detection, and by exploring the properties of post-selected circuits. In order to treat post-selection in CVs we consider finitely-resolved homodyne detectors, corresponding to a realistic scheme based on discrete probability distributions of the measurement outcomes. The unavoidable errors stemming from the use of finitely squeezed states are suppressed through a qubit-into-oscillator GKP encoding of quantum information,…

Benchmarking parameter-free AMaLGaM on functions with and without noise.

2013

We describe a parameter-free estimation-of-distribution algorithm (EDA) called the adapted maximum-likelihood Gaussian model iterated density-estimation evolutionary algorithm (AMaLGaM-ID[Formula: see text]A, or AMaLGaM for short) for numerical optimization. AMaLGaM is benchmarked within the 2009 black box optimization benchmarking (BBOB) framework and compared to a variant with incremental model building (iAMaLGaM). We study the implications of factorizing the covariance matrix in the Gaussian distribution, to use only a few or no covariances. Further, AMaLGaM and iAMaLGaM are also evaluated on the noisy BBOB problems and we assess how well multiple evaluations per solution can average ou…

Non Linear Fitting Methods for Machine Learning

2017

This manuscript presents an analysis of numerical fitting methods used for solving classification problems as discriminant functions in machine learning. Non linear polynomial, exponential, and trigonometric models are mathematically deduced and discussed. Analysis about their pros and cons, and their mathematical modelling are made on what method to chose for what type of highly non linear multi-dimension problems are more suitable to be solved. In this study only deterministic models with analytic solutions are involved, or parameters calculation by numeric methods, which the complete model can subsequently be treated as a theoretical model. Models deduction are summarised and presented a…

Defining poor prognosis markers of implantation for embryo selection by time-lapse

2012

Cost of host radiation in an RNA virus.

2000

Abstract Although host radiation allows a parasite to expand its ecological niche, traits governing the infection of multiple host types can decrease fitness in the original or alternate host environments. Reasons for this reduction in fitness include slower replication due to added genetic material or modifications, fitness trade-offs across host environments, and weaker selection resulting from simultaneous adaptation to multiple habitats. We examined the consequences of host radiation using vesicular stomatitis virus (VSV) and mammalian host cells in tissue culture. Replicate populations of VSV were allowed to evolve for 100 generations on the original host (BHK cells), on either of two …