Search results for " and ocular physiology"
showing 10 items of 237 documents
Perception and processing of odor mixtures
2012
Perception and processing of odor mixtures. Olfaktologie / Gustologie
Exploring the odorant and molecular characteristics of molecules sharing the odour notes of an aroma blending mixture
2021
Online event (Live and on-demand); International audience; To perceive a huge number of odors from few hundreds ORs, the human olfactory system encodes odor identities by an olfactory scheme whereby one olfactory receptor (OR) recognizes multiple odorants while one odorant activates different combinations of ORs [1, 2]. Odors perceived in our environment are mainly the result of mixtures of odorants, but the specific mechanisms involved in their processing remain poorly understood [3]. In previous studies performed at INRAE-CSGA [4], the perception of a mixture of ethyl isobutyrate (Et iB, strawberry-like odor, STR) and ethyl maltol (Et-M, caramel-like odor, CAR) was investigated in compari…
Mouse olfactory sensory neurons' plasticity induced by postnatal odorant exposure: anatomical, molecular and physiological consequences
2012
Mouse olfactory sensory neurons' plasticity induced by postnatal odorant exposure: anatomical, molecular and physiological consequences. 8. FENS forum of neuroscience
An olfactory receptor detects waxy, fatty and rose odors
2008
An olfactory receptor detects waxy, fatty and rose odors. Salon Européen de la Recherche et de l’Innovation
Advances in immunopathogenesis of macrophage activation syndrome during rheumatic inflammatory diseases: toward new therapeutic targets?
2017
Introduction: Macrophage activation syndrome (MAS) is a severe, hyperinflammatory life-threatening syndrome, generally complicating different rheumatic diseases. Despite the severity of the disease, little is known about the pathogenic mechanisms and, thus, possible targeted therapies in the management of these patients. Areas covered: In this review, we aimed to update the current pathogenic knowledge of MAS, during rheumatic diseases, focusing mainly on immunologic abnormalities and on new possible therapeutic strategies. Expert commentary: The difficult pathogenic scenario of MAS, in which genetic defects, predisposing diseases, and triggers are mixed together with the high mortality rat…
Long-Term Potentiation in the Neonatal Rat Barrel Cortex In Vivo
2012
Long-term potentiation (LTP) is important for the activity-dependent formation of early cortical circuits. In the neonatal rodent barrel cortex, LTP has been studied only in vitro . We combined voltage-sensitive dye imaging with extracellular multielectrode recordings to study whisker stimulation-induced LTP in the whisker-to-barrel cortex pathway of the neonatal rat barrel cortex in vivo . Single whisker stimulation at 2 Hz for 10 min induced an age-dependent expression of LTP in postnatal day (P) 0 to P14 rats, with the strongest expression of LTP at P3–P5. The magnitude of LTP was largest in the activated barrel-related column, smaller in the surrounding septal region, and no LTP could b…
2002
Previous observations have suggested a role for nitric oxide in the activity of the globus pallidus, but this functional involvement has not yet been tested in vivo. The extracellular activity of single units of the globus pallidus was recorded, and neuronal nitric oxide synthase was inhibited by systemically administering 7-nitro-indazole to a group of anaesthetised rats. Forty-five per cent of cells responded with a decrease in the firing rate. In another group of rats, the microiontophoretic administration of 3-morpholino-sydnonimin-hydrocloride (a nitric oxide donor) induced an increase in neuronal firing rate (24/28 cells), whereas the administration of Nω-nitro-L-arginine methyl ester…
Effects of an invasive crayfish on the littoral macroinvertebrates of large boreal lakes are habitat specific
2013
Summary Invasive crayfish are widely acknowledged to have negative effects on benthic food webs in lakes, but few studies have investigated such effects at wider spatial scales and in varying habitats under natural conditions. We examined the effects of introduced signal crayfish (Pacifastacus leniusculus) on the macroinvertebrate assemblages of different habitats in two large boreal lakes. We evaluated whether the density, taxon richness and species composition are altered by the non-native crayfish and whether the responses are similar for stony and vegetated habitats and across a depth gradient. We also studied the influence of crayfish on periphyton biomass at stony sites, as a potentia…
Neurotrophic effects of central nicotinic receptor activation
2000
A growing number of data have shown that compounds interacting with neuronal nicotinic acetylcholine receptors (nAChRs) have, both in vivo and in vitro, the potential to be neuroprotective and that treatment with nAChR agonists elicit long-lasting improvement of cognitive performance in a variety of behavioural tests in rats, monkeys and humans. Epidemiological and clinical studies suggested also a potential neuroprotective/trophic role of (-)-nicotine in neurodegenerative disease, such as Alzheimer's disease and Parkinson's disease. This neuroprotective/trophic role of nAChR activation has been mainly mediated by alpha7 and alpha4beta2 nAChR subtypes, as evidenced using selective nAChR ant…
Arm swing during skating at different skiing speeds affects skiing mechanics and performance
2018
Arm swing has been shown to lead to greater maximal speed and movement economy in cross -country skiing. The current study aimed to investigate how arm swing alters skiing mechanics and contributes to performance and acceleration of the athlete’s centre of mass (COM). While skiing on snow seven highly skilled cross -country skiers simulated V2 -alternate skating without using ski poles and with double or single arm swing and without arm swing . During leg push -off the linear momentum of the body increased due to arm swing. Simultaneously, linear momentum of the arm(s) decreased in arm swing trials, indicating a transfer of momentum from arms to the rest of the body and being more prevalent…