Search results for " anticancer"

[1,2]oxazole[5,4-e]isoindoles as promising drugs for anticancer chemotherapy

2015

Consensus nomenclature for CD8(+) T cell phenotypes in cancer

2015

International audience; Whereas preclinical investigations and clinical studies have established that CD8+ T cells can profoundly affect cancer progression, the underlying mechanisms are still elusive. Challenging the prevalent view that the beneficial effect of CD8+ T cells in cancer is solely attributable to their cytotoxic activity, several reports have indicated that the ability of CD8+ T cells to promote tumor regression is dependent on their cytokine secretion profile and their ability to self-renew. Evidence has also shown that the tumor microenvironment can disarm CD8+ T cell immunity, leading to the emergence of dysfunctional CD8+ T cells. The existence of different types of CD8+ T…

Synthesis of new heteroanalogues of “tripentones”

2015

Preliminary data on antiproliferative effects in haemocyte extracts of the ascidian Styela plicata (Stolidobranchiata, Styelidae)

2008