Search results for " attractant"

showing 4 items of 44 documents

Study of mechanisms of action of an immunotherapy by triacyl lipid A in humans

2013

Immunotherapy acting at the primary tumor site and preventing the development of metastases is one of the strategies for treatment of patients with cancer. To improve the efficiency of the latter, it is necessary to understand how it induces tumor cell death. In the laboratory, it was observed the cure of PROb tumors in rats BDIX by the triacyl lipid A. It has been shown that this effect involved the immune system involving interactions with TLRs present in many tumor cells and innate immunity cells such as neutrophils.In this work, we investigated the possible involvement of neutrophils in the antitumor activity of triacyl lipid A in humans.In a Phase 1 study in patients with refractory so…

[SDV.MHEP] Life Sciences [q-bio]/Human health and pathologyGranzyme BPolynucléaires neutrophilesImmunothérapie[ SDV.MHEP ] Life Sciences [q-bio]/Human health and pathologyNo english keywordPhase 1Triacyl lipide A[SDV.MHEP]Life Sciences [q-bio]/Human health and pathologyChimio attractantsCancer
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Degradation of an alkaloid pheromone from the pale-brown chafer, Phyllopertha diversa (Coleoptera: Scarabaeidae), by an insect olfactory cytochrome P…

1999

AbstractThe pale-brown chafer, Phyllopertha diversa, utilizes an unusual alkaloid, 1,3-dimethyl-2,4-(1H,3H)-quinazolinedione, as its sex pheromone. This compound is rapidly degraded in vitro by the antennal protein extracts from this scarab beetle. Demethylation at the N-1 position and hydroxylation of the aromatic ring have been identified as the major catabolic pathways. The enzyme responsible for the pheromone degradation is membrane-bound, requires NAD(P)H for activity and is sensitive to cytochrome P450 inhibitors, such as proadifen and metyrapone. The ability to metabolize this unusual pheromone was not detected in 12 species tested, indicating that the P450 system, specific to male P…

pheromone-degrading enzymemedia_common.quotation_subjectBiophysicsInsectOlfactionscarab beetleBiochemistryMass SpectrometryHydroxylationchemistry.chemical_compoundAlkaloidsCytochrome P-450 Enzyme SystemStructural BiologyMicrosomesBotanyGeneticsAnimalsCytochrome P-450 Enzyme InhibitorsEnzyme InhibitorsSex AttractantsMolecular BiologyChromatography High Pressure LiquidDemethylationmedia_commonbiologyMolecular StructureProadifenCytochrome P450Cell BiologyMetyraponeProadifenColeopteraBiochemistrychemistrySex pheromonebiology.proteinQuinazolinesPheromoneInsect ProteinsChromatography Thin Layerpheromone inactivationolfactionFEBS letters
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Necrobia rufipes (De geer) infestation in pet food packaging and setup of a monitoring trap

2020

Simple Summary Necrobia rufipes (Coleoptera: Cleridae) is an emerging pest of pet food stores. Information on infestation modalities for this pest is absent and specific monitoring tools are missing. In this paper, the adults’ and larvae’s ability to enter into pet food packaging was evaluated. Furthermore, to set up of a monitoring trap behavioral bioassays were carried out: testing two adhesive surfaces, one generally used in mouse glue trap and the other used in cockroach trap, to evaluate their ability in avoiding insects’ escape; screening different molecules, as candidate food attractants: methyl cyclopentenolone, squalene and stearic acid. The results evidenced that N. rufipes enter …

red-legged ham beetleSettore AGR/11 - Entomologia Generale E Applicatafungipackagingadhesive trapsadhesive traplcsh:Qfood attractantlcsh:Sciencefood attractantsArticle
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Ultrastructure of posterior sternal glands of Macrotermes annandalei (Silvestri): new members of the sexual glandular set found in termites (Insecta)

2004

0362-2525 (Print) Comparative Study Journal Article; In female alates of Macrotermes annandalei, two types of abdominal glands are involved in the secretion of sex pheromone. Tergal glands are found at the anterior margin of tergites 6-10 and posterior sternal glands (PSGs) are located at the anterior margin of sternites 6-7. The cytological features of both types of glands are quite similar. The fine structural organization of PSGs is studied more precisely and described for the first time. The glandular cuticle is pitted with narrow apertures corresponding to the openings of numerous subcuticular pouches. Several Class 3 glandular units open in each pouch. One canal cell and one secretory…

stomatognathic systemSex Attractants/secretionIsoptera/physiology/*ultrastructureAbdomen/anatomy & histologyAnimalsFemaleScent Glands/secretion/*ultrastructurePhylogeny
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