Search results for " bank"

showing 10 items of 502 documents

Food tray sealing fault detection using hyperspectral imaging and PCANet

2020

Abstract Food trays are very common in shops and supermarkets. Fresh food packaged in trays must be correctly sealed to protect the internal atmosphere and avoid contamination or deterioration. Due to the speed of production, it is not possible to have human quality inspection. Thus, automatic fault detection is a must to reach high production volume. This work describes a deep neural network based on Principal Component Analysis Network (PCANet) for food tray sealing fault detection. The input data come from hyperspectral cameras, showing more characteristics than regular industrial cameras or the human eye as they capture the spectral properties for each pixel. The proposed classification…

0209 industrial biotechnologyPixelbusiness.industryComputer scienceFeature vectorIndústria agroalimentària020208 electrical & electronic engineeringHyperspectral imagingPattern recognition02 engineering and technologyAliments ConservacióFilter bankFault detection and isolationControl de qualitatSupport vector machine020901 industrial engineering & automationTrayControl and Systems EngineeringPrincipal component analysis0202 electrical engineering electronic engineering information engineeringArtificial intelligencebusiness
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Bidimensional Structure of the Orthorexia: Development and Initial Validation of a New Instrument

2018

La ortorexia nerviosa puede entenderse como una preocupa- ción extrema o excesiva con alimentarse de comida considerada sana. Se puede distinguir entre ortorexia nerviosa y ortorexia saludable (interés en comer sano). Hasta ahora, no hay ningún instrumento disponible para eva- luar cada aspecto de la ortorexia con suficientes garantías psicométricas. El objetivo de este estudio era doble. Primero, desarrollar y validar un nuevo cuestionario de ortorexia –la Teruel Orthorexia Scale– y, segundo, analizar la asociación con otros contructos psicológicos y trastornos teóricamente relacionados con la ortorexia nerviosa: síntomas de trastornos de la alimen- tación, síntomas de trastorno obsesivo-c…

0301 basic medicine030109 nutrition & dieteticsQuestionnairequestionnaire.Item bankEating disorderTest validityComputer-assisted web interviewingPerfectionism (psychology)medicine.diseasemedicine.disease_causeBF1-990159.9(05)03 medical and health sciencesEating disordersRating scaleOrthorexia nervosaValidationmedicinePsychologyPsychologyGeneral PsychologyOrthorexia nervosaPsychopathologyClinical psychology
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Adherence to a healthy lifestyle and multiple sclerosis: a case–control study from the UK Biobank

2020

Background: Multiple sclerosis (MS) is a common and disabling condition. The importance of healthy lifestyle for this disease is poorly explored. Objective: To test whether adherence to healthier lifestyle patterns is associated with a lower presence of multiple sclerosis (MS). Methods: By using a case–control design, we investigated the combined association of four healthy lifestyle-related factors (no current smoking, healthy diet, exercising regularly, body mass index <30 kg/m2) and the prevalence of MS. A logistic regression analysis, adjusted for potential confounders, was used and data reported as odds ratios (ORs) with their 95% confidence intervals (CIs). Results: 728 participant…

0301 basic medicineGerontologyobesityMultiple Sclerosishealthy dietMedicine (miscellaneous)Diseasesmoking03 medical and health sciences0302 clinical medicineRisk Factorshealthy lifestyleHumansMedicineMultiple sclerosiLife StyleBiological Specimen Banks030109 nutrition & dieteticsNutrition and Dieteticsexercisebusiness.industryGeneral NeuroscienceMultiple sclerosisCase-control studyGeneral MedicineUK biobankmedicine.diseaseNUTRITION&DIETETICSHealthy dietBiobankObesityUnited KingdomCase-Control Studiesbusiness030217 neurology & neurosurgery
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The Older Finnish Twin Cohort : 45 Years of Follow-up

2019

AbstractThe older Finnish Twin Cohort (FTC) was established in 1974. The baseline survey was in 1975, with two follow-up health surveys in 1981 and 1990. The fourth wave of assessments was done in three parts, with a questionnaire study of twins born during 1945–1957 in 2011–2012, while older twins were interviewed and screened for dementia in two time periods, between 1999 and 2007 for twins born before 1938 and between 2013 and 2017 for twins born in 1938–1944. The content of these wave 4 assessments is described and some initial results are described. In addition, we have invited twin-pairs, based on response to the cohortwide surveys, to participate in detailed in-person studies; these …

0301 basic medicineMaleAgingHORMONE-REPLACEMENT THERAPYphysical activityBLOOD-PRESSURECohort Studies0302 clinical medicineSurveys and QuestionnairesTwins Dizygotickohonnut verenpaineMedicinekohorttitutkimusGenetics (clinical)FinlandBiological Specimen BanksAged 80 and overalcohol1184 Genetics developmental biology physiologyObstetrics and GynecologytwinsMiddle AgedBiobankPOPULATION-BASED TWINepigenetiikkaDEPRESSIVE SYMPTOMSCohortSKELETAL-MUSCLEFemalefyysinen aktiivisuusCohort studyAdulthypertensionAlcohol DrinkinglongitudinalPhysical activityreviewPAIRS DISCORDANTpitkittäistutkimussmokingENVIRONMENTAL-INFLUENCES03 medical and health sciencesTIME PHYSICAL-ACTIVITYtupakointiDiseases in Twinscohort studyDementiaHumansGENOME-WIDE ASSOCIATIONalkoholi (päihteet)Depressive symptomsQuestionnaire studyAgedkaksostutkimusepigeneticsbusiness.industryagingBaseline surveyTwins Monozygoticmedicine.diseasekaksoset030104 developmental biologyikääntyminenPediatrics Perinatology and Child HealthTELOMERE LENGTHbusiness030217 neurology & neurosurgeryDemographyFollow-Up Studiesdementia
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Improved in vivo efficacy of clinical-grade cryopreserved human hepatocytes in mice with acute liver failure.

2020

Clinical hepatocyte transplantation short-term efficacy has been demonstrated; however, some major limitations, mainly due to the shortage of organs, the lack of quality of isolated cells and the low cell engraftment after transplantation, should be solved for increasing its efficacy in clinical applications. Cellular stress during isolation causes an unpredictable loss of attachment ability of the cells, which can be aggravated by cryopreservation and thawing. In this work, we focused on the use of a Good Manufacturing Practice (GMP) solution compared with the standard cryopreservation medium, the University of Wisconsin medium, for the purpose of improving the functional quality of cells …

0301 basic medicineMaleCancer ResearchCell SurvivalImmunologyCellCell- and Tissue-Based TherapyCell SeparationTissue BanksPharmacologyCryopreservation03 medical and health sciencesMice0302 clinical medicineCryoprotective AgentsIn vivomedicineImmunology and AllergyAnimalsHumansViability assayGenetics (clinical)CryopreservationTransplantationbusiness.industryCell adhesion moleculeLiver failureCell BiologyLiver Failure AcuteIn vitroTransplantationDisease Models Animal030104 developmental biologymedicine.anatomical_structureOncologyLiver030220 oncology & carcinogenesisHepatocytesbusinessCell Adhesion MoleculesCytotherapy
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Conf-VLKA: A structure-based revisitation of the Virtual Lock-and-key Approach

2016

In a previous work, we developed the in house Virtual Lock-and-Key Approach (VLKA) in order to evaluate target assignment starting from molecular descriptors calculated on known inhibitors used as an information source. This protocol was able to predict the correct biological target for the whole dataset with a good degree of reliability (80%), and proved experimentally, which was useful for the target fishing of unknown compounds. In this paper, we tried to remodel the previous in house developed VLKA in a more sophisticated one in order to evaluate the influence of 3D conformation of ligands on the accuracy of the prediction. We applied the same previous algorithm of scoring and ranking b…

0301 basic medicineMaterials Chemistry2506 Metals and AlloysInhibitorStructure-basedComputer scienceProtein ConformationProtein Data Bank (RCSB PDB)Molecular ConformationTarget fishingMolecular Dynamics Simulationcomputer.software_genreLigands01 natural sciencesDockingVlka03 medical and health sciencesMolecular descriptorMaterials ChemistryHumansPhysical and Theoretical ChemistryCluster analysisDatabases ProteinSimulationSpectroscopyBinding SitesProteinscomputer.file_formatDescriptorProtein Data BankComputer Graphics and Computer-Aided Design0104 chemical sciencesMolecular Docking Simulation010404 medicinal & biomolecular chemistry030104 developmental biologyProtein–ligand dockingBiological targetDocking (molecular)Biological targetStructure basedLigand-basedData miningcomputerAlgorithmsSoftwareProtein Binding
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Conformational dynamism for DNA interaction in the Salmonella RcsB response regulator

2017

17 páginas, 7 figuras, 1 tabla

0301 basic medicineModels MolecularSalmonella typhimuriumProtein Data Bank (RCSB PDB)Plasma protein bindingBiologyCrystallography X-RayDNA-binding protein03 medical and health sciencesBacterial ProteinsProtein DomainsStructural BiologyGeneticsAmino Acid SequencePhosphorylationTranscription factorSequence Homology Amino AcidEffectorPromoterDNACell biologyResponse regulator030104 developmental biologyRegulonBiochemistryNucleic Acid ConformationProtein BindingNucleic Acids Research
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Coordination of the biliverdin D-ring in bacteriophytochromes.

2018

Phytochrome proteins translate light into biochemical signals in plants, fungi and microorganisms. Light cues are absorbed by a bilin chromophore, leading to an isomerization and a rotation of the D-ring. This relays the signal to the protein matrix. A set of amino acids, which is conserved across the phytochrome superfamily, holds the chromophore in the binding pocket. However, the functional role of many of these amino acids is not yet understood. Here, we investigate the hydrogen bonding network which surrounds the D-ring of the chromophore in the resting (Pr) state. We use UV/vis spectroscopy, infrared absorption spectroscopy and X-ray crystallography to compare the photosensory domains…

0301 basic medicineModels MolecularStereochemistryProtein ConformationProtein Data Bank (RCSB PDB)General Physics and Astronomyphytochrome proteinsbakteerit03 medical and health scienceschemistry.chemical_compoundProtein structureBacterial ProteinsProteobacteriabiochemical signalsDeinococcusPhysical and Theoretical ChemistryStigmatella aurantiacaBiliverdinBinding SitesbiologyPhytochromeBiliverdineta1182Deinococcus radioduransHydrogen BondingChromophorebiology.organism_classificationPhotochemical ProcessesD-ring030104 developmental biologychemistryproteiinitvalokemiaDeinococcusPhytochromeProtein BindingPhysical chemistry chemical physics : PCCP
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Alterations in reelin and reelin receptors in Down syndrome.

2019

Reelin is an extracellular matrix glycoprotein that modulates synaptic function and plasticity, with a crucial role in neuronal migration. Changes in the expression of this protein have been reported in neurodegenerative diseases, such as Alzheimer's disease (AD). This molecule is produced by Cajal-Retzius neurons during development and by inhibitory neurons in the adult nervous system. Individuals with Down syndrome (DS) present an early development of AD; therefore, we analyzed the alterations in this molecule and its receptors in the murine model for DS Ts65Dn as well as in human with DS. We performed immunofluorescence analysis for reelin and its receptors very-low-density lipoprotein r…

0301 basic medicineNervous systemAdultMaleReceptor expressionCell Adhesion Molecules NeuronalNerve Tissue ProteinsReceptors Cell SurfaceTissue BanksInhibitory postsynaptic potential03 medical and health sciencesMice0302 clinical medicinemedicineAnimalsHumansReelinReceptorLDL-Receptor Related ProteinsAgedTemporal cortexNeuronsExtracellular Matrix ProteinsbiologyCell adhesion moleculeGeneral NeuroscienceSerine EndopeptidasesMiddle AgedTemporal LobeCell biologyDisease Models AnimalReelin Protein030104 developmental biologymedicine.anatomical_structurenervous systemReceptors LDLbiology.proteinDown Syndrome030217 neurology & neurosurgeryLipoproteinNeuroreport
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Harmonising and linking biomedical and clinical data across disparate data archives to enable integrative cross-biobank research

2015

A wealth of biospecimen samples are stored in modern globally distributed biobanks. Biomedical researchers worldwide need to be able to combine the available resources to improve the power of large-scale studies. A prerequisite for this effort is to be able to search and access phenotypic, clinical and other information about samples that are currently stored at biobanks in an integrated manner. However, privacy issues together with heterogeneous information systems and the lack of agreed-upon vocabularies have made specimen searching across multiple biobanks extremely challenging. We describe three case studies where we have linked samples and sample descriptions in order to facilitate glo…

0301 basic medicineNetherlands Twin Register (NTR)Databases FactualComputer scienceInformation Storage and RetrievalSample (statistics)Ontology (information science)Endocrinology and DiabetesBioinformaticscomputer.software_genredata archivesArticle03 medical and health sciencesSDG 17 - Partnerships for the GoalsSDG 3 - Good Health and Well-beingGenetics/dk/atira/pure/keywords/cohort_studies/netherlands_twin_register_ntr_Use casebiomedical dataGenetics (clinical)Biological Specimen BanksGenetics & Heredity0604 GeneticsBioinformatics (Computational Biology)ta112ta1184/dk/atira/pure/sustainabledevelopmentgoals/partnershipsData scienceBiobank3. Good healthcross-biotank research030104 developmental biologyProject planningExchange of informationDisparate systemPrivacyBioinformatik (beräkningsbiologi)/dk/atira/pure/sustainabledevelopmentgoals/good_health_and_well_beingclinical datacomputerData integrationEuropean Journal of Human Genetics
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