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Makroekonomikas vides ietekme uz tautsaimniecības nozaru sistemātisko risku

2021

Pasaulē vērojamas krasas sistemātiskā riska atšķirības starp dažādām tautsaimniecības nozarēm dažādās valstīs, un tas rada jautājumus par šo atšķirību cēloņiem. Par pamatu atšķirībām tiek minēta makroekonomiskās vides ietekme un notikumi tautsaimniecībā, kas atspoguļojas ar pārmaiņām aktīvu tirgos. Taču neviennozīmīgi tiek skaidrots, vai atšķiras tautsaimniecības nozaru jutīgums, vai atšķirīga ir makroekonomikas faktoru ietekme dažādos pasaules aktīvu tirgos. Maģistra darba mērķis ir novērtēt makroekonomikas faktoru ietekmi uz nozaru jūtīgumu pret tautsaimniecības mēroga akciju tirgus tendencēm, salīdzināt rezultātus lielākajos pasaules aktīvu tirgos, kā arī skaidrot makroekonomikas faktoru…

tirgus risksnozaru jutībamakroekonomiskā videEkonomikatautsaimniecības nozaru betassistemātiskais risks
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Double copies of blaKPC-3::Tn4401a on an IncX3 plasmid in Klebsiella pneumoniae successful clone ST512 from Italy

2015

ABSTRACT A carbapenem-resistant sequence type 512 (ST512) Klebsiella pneumoniae carbapenemase 3 (KPC-3)-producing K. pneumoniae strain showing a novel variant plasmid content was isolated in Palermo, Italy, in 2014. ST512 is a worldwide successful clone associated with the spread of bla KPC genes located on the IncFIIk pKpQIL plasmid. In our ST512 strain, the bla KPC-3 gene was unusually located on an IncX3 plasmid, whose complete sequence was determined. Two copies of bla KPC-3 ::Tn 4401a caused by intramolecular transposition events were detected in the plasmid.

transposonsequence analysispolymerase chain reactionDrug ResistanceGene DosageSettore MED/42 - Igiene Generale E Applicatabacterial proteinbeta-Lactamaseopen reading framecarbapenemasePlasmidminocyclineplasmid DNAmeropenemPharmacology (medical)geneticscolistincefpodoximeceftazidime610 Medicine & healthCarbapenemBacterialpolymyxin Btimentingene expression regulationbacteriumKlebsiella pneumoniae carbapenemase 3 producing Klebsiella pneumoniae3. Good healthantiinfective agentmicrobial sensitivity testKlebsiella pneumoniaeItalypriority journaltigecyclineMultipleclone (Java method)cefotaxime030106 microbiologyKlebsiella pneumoniae carbapenemase 3tobramycinMicrobial Sensitivity Testsgentamicinpiperacillin plus tazobactamchemistryGene dosageArticleMicrobiology03 medical and health sciencesComplete sequenceClone CellOpen Reading FramesertapenemBacterial Proteinsmultidrug resistanceextensively drug resistant bacteriumAnti-Bacterial AgentcefepimePharmacologylevofloxacinmicrobiologycefoxitinbiochemical phenomena metabolism and nutritionbacterial infections and mycosesVirologyAnti-Bacterial Agents; Bacterial Proteins; Carbapenems; Clone Cells; Drug Resistance Multiple Bacterial; Gene Dosage; Italy; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Open Reading Frames; Plasmids; beta-Lactamases; DNA Transposable Elements; Gene Expression Regulation Bacterial; Pharmacology (medical); Pharmacology; Infectious Diseasesantibiotic sensitivityClone CellsKlebsiella InfectionsceftriaxoneCarbapenemsbacterial genetics0301 basic medicinemolecular cloningSettore MED/07 - Microbiologia E Microbiologia ClinicaKlebsiella pneumoniaeTransposition (music)Drug Resistance Multiple Bacterialpolycyclic compoundsgenetic screeningcell clonecarbapenem derivativeKlebsiella infectionunclassified drugAnti-Bacterial AgentsInfectious Diseasesbacterial genePlasmidsenzymologydoripenemBiologyminimum inhibitory concentrationbeta-Lactamasesbeta lactamaseMechanisms of ResistanceciprofloxacinAmikacin; aztreonam; carbapenemase; cefepime; cefotaxime; cefoxitin; cefpodoxime; ceftazidime; ceftriaxone; ciprofloxacin; colistin; cotrimoxazole; doripenem; doxycycline; ertapenem; gentamicin; imipenem; Klebsiella pneumoniae carbapenemase 3; levofloxacin; meropenem; minocycline; piperacillin plus tazobactam; plasmid DNA; polymyxin B; tigecycline; timentin; tobramycin; unclassified drug; antiinfective agent; bacterial protein; beta lactamase; carbapenem derivative; transposon antibiotic sensitivity; Article; bacterial gene; bacterial genetics; bacterial strain; bacterium; bacterium detection; bacterium isolation; Escherichia coli; extensively drug resistant bacterium; gene dosage; genetic screening; Italy; Klebsiella pneumoniae; Klebsiella pneumoniae carbapenemase 3 producing Klebsiella pneumoniae; minimum inhibitory concentration; molecular cloning; nonhuman; polymerase chain reaction; priority journal; sequence analysis; cell clone; chemistry; drug effects; enzymology; gene expression regulation; genetics; isolation and purification; Klebsiella infection; Klebsiella pneumoniae; metabolism; microbial sensitivity test; microbiology; multidrug resistance; open reading frame; plasmid; transposon Anti-Bacterial Agents; Bacterial Proteins; beta-Lactamases; Carbapenems; Clone Cells; DNA Transposable Elements; Drug Resistance Multiple Bacterial; Gene Dosage; Gene Expression Regulation Bacterial; Italy; Klebsiella Infections; Klebsiella pneumoniae; Microbial Sensitivity Tests; Open Reading Frames; Plasmidsplasmidbacterium isolationEscherichia coliGeneAmikacinbacterium detectionnonhumandoxycyclineisolation and purificationGene Expression Regulation Bacterialbiology.organism_classificationbacterial straincotrimoxazoleOpen reading frameDNA Transposable Elementdrug effectsDNA Transposable Elementsmetabolismaztreonamimipenem
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Litigating Treaties by Means of Article 46 of the Vienna Convention on the Law of Treaties

2022

The contribution deals with Article 46 of the Vienna Convention and related national and internationa case-law.

treaty law invalidity of treaties relationship between international and domestic legal orders international adjudicationSettore IUS/13 - Diritto Internazionale
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Co-Evolutionary Coupling Between Captured and Uncaptured GDP Cycles : Cross Learning from Amazon and Finland Models for Sustainability

2019

A solution to the critical problem of a dilemma between R&D expansion and productivity decline that a majority of information and communication technology (ICT) leaders have been confronting in the digital economy is expected. It can be expected by a spinoff from economic functionality-seeking GDP-based coevolution cycle to supra-functionality beyond an economic value-seeking uncaptured GDP-driven coevolution cycle. However, the transformation dynamism remains a black box. By means of numerical simulations based on empirical analyses of the development trajectories of global ICT leaders, focusing on Amazon and Finland, together with an intensive review of preceding analyses, this paper atte…

tutkimus- ja kehittämistoimintatransformationtieto- ja viestintätekniikkatuottavuusuusi talousuncaptured GDPdilemma between R&D and productivitybruttokansantuoteAmazonFinlandco-evolutionary coupling
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Evidence of Single State Dominance in the Two-Neutrino Double-β Decay of ^{82}Se with CUPID-0.

2019

We report on the measurement of the two-neutrino double-β decay of ^{82}Se performed for the first time with cryogenic calorimeters, in the framework of the CUPID-0 experiment. With an exposure of 9.95 kg yr of Zn^{82}Se, we determine the two-neutrino double-β decay half-life of ^{82}Se with an unprecedented precision level, T_{1/2}^{2ν}=[8.60±0.03(stat) _{-0.13}^{+0.19}(syst)]×10^{19}  yr. The very high signal-to-background ratio, along with the detailed reconstruction of the background sources allowed us to identify the single state dominance as the underlying mechanism of such a process, demonstrating that the higher state dominance hypothesis is disfavored at the level of 5.5σ.

two-neutrinos double-β decay; nuclear matrix elements; scintillating cryogenic calorimetersDouble beta decay exited states nuclear modelnuclear matrix elementshiukkasfysiikkaydinfysiikkatwo-neutrinos double-β decayscintillating cryogenic calorimetersPhysical review letters
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2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation

2020

2020 ESC Guidelines for the management of acute coronary syndromes in patients presenting without persistent ST-segment elevation

unstable anginaMyocardial ischaemia[SDV]Life Sciences [q-bio]Vascular damage Radboud Institute for Health Sciences [Radboudumc 16]dual antithrombotic therapyGuidelineheparin030204 cardiovascular system & hematologyPlatelet inhibitionantiplatelet0302 clinical medicineST segmentMedicinedabigatranMyocardial infarctionguidelinesglycoprotein iib/iiia inhibitorsanticoagulationNon-ST Elevated Myocardial InfarctionrivaroxabanComputingMilieux_MISCELLANEOUSreproductive and urinary physiologydiabetesbleedingsbivalirudinatherothrombosiDisease ManagementangioplastyGuidelines • acute cardiac care • acute coronary syndrome • angioplasty • anticoagulation • antiplatelet • apixaban • aspirin • atherothrombosis • betablockers • bleedings • bivalirudin • bypass surgery • cangrelor • chest pain unit • clopidogrel • dabigatran • diabetes • dual antithrombotic therapy • early invasive strategy • edoxaban • enoxaparin • European Society of Cardiology • fondaparinux • glycoprotein IIb/ IIIa inhibitors • heparin • high-sensitivity troponin • minoca • myocardial ischaemia • myocardial infarction • nitrates • non-ST-elevation myocardial infarction • platelet inhibition • prasugrel • recommendations • revascularization • rhythm monitoring • rivaroxaban • stent • ticagrelor • triple therapy • unstable anginaenoxaparinGeneral MedicineClopidogrel3. Good healthearly invasive strategymyocardial infarctiontriple therapy030220 oncology & carcinogenesisHigh sensitivity troponinembryonic structuresCardiologyPlatelet aggregation inhibitorrevascularizationbiological phenomena cell phenomena and immunityCardiology and Cardiovascular MedicineTicagrelormedicine.drugHumanrecommendationAcute coronary syndromemedicine.medical_specialtyaspiringlycoprotein IIb/IIIa inhibitornon-ST-elevation myocardial infarctionapixabanrhythm monitoringEuropean Society of Cardiologyticagrelor03 medical and health sciencesnitrateatherothrombosisbetablockersInternal medicineacute cardiac careminocachest pain unitDiseases of the circulatory (Cardiovascular) systemHumansIn patientAcute Coronary SyndromeclopidogrelUnstable anginaurogenital systemnitratesbusiness.industryfondaparinuxbetablockerArrhythmias Cardiac030229 sport sciencesbleedingmedicine.diseasemyocardial ischaemiaplatelet inhibitionprasugreldiabeteGlycoprotein IIb/IIIa inhibitorsRC666-701bypass surgerySettore MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARErecommendationsedoxabanhigh-sensitivity troponinstentbusinessPlatelet Aggregation Inhibitorscangrelor
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Systematic Comparison of Epidemic and Non-Epidemic Carbapenem Resistant Klebsiella pneumoniae Strains

2021

Over the past few decades, extensively drug resistant (XDR) resistant Klebsiella pneumoniae has become a notable burden to healthcare all over the world. Especially carbapenemase-producing strains are problematic due to their capability to withstand even last resort antibiotics. Some sequence types (STs) of K. pneumoniae are significantly more prevalent in hospital settings in comparison to other equally resistant strains. This provokes the question whether or not there are phenotypic characteristics that may render certain K. pneumoniae more suitable for epidemic dispersal between patients, hospitals, and different environments. In this study, we selected seven epidemic and non-epidemic ca…

virulenceantibiotic resistanceextended-spectrum beta-lactamaselcsh:QR1-502XDR Klebsiella pneumoniaeepidemiclcsh:MicrobiologyFrontiers in Cellular and Infection Microbiology
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Una más de la familia. Au pairs atrapadas entre el capital humano y la economía moral

2018

In contemporary societies we are witnessing an expansion of the messages of human capital. These messages have as their central dimension idea of the self-entrepreneur, which implies a deepening in the logic of activation, while blurring the wage relations. In this scenario, young people with university degrees are becoming a favourite target in the offensive of human capital. The penetration of these human capital messages can be seen in the discourses of young university students who have been forced to leave the country during the crisis. In the present text we approach the discourses of young women who came out as au pairs. The characteristics of this figure place it in a space halfway …

we explore the features that may be prefiguring the working conditions to which neo-liberalism seems to lead Au pairemprendimientoprecariousness. 95 108with little protection and conditions that in some cases border on exploitation. Through the stories of these womenentrepreneurship:SOCIOLOGÍA [UNESCO]1137-7038 8537 Arxius de sociologia 514142 2018 39 6874489 Una más de la familia. Au pairs atrapadas entre el capital humano y la economía moral Muñoz RodríguezDavidwhich implies a deepening in the logic of activationyoung people with university degrees are becoming a favourite target in the offensive of human capital. The penetration of these human capital messages can be seen in the discourses of young university students who have been forced to leave the country during the crisis. In the present text we approach the discourses of young women who came out as au pairs. The characteristics of this figure place it in a space halfway between training and employmentUNESCO::SOCIOLOGÍASantos Ortegawhile blurring the wage relations. In this scenarioAu pairprecariedadhuman capitalcapital humanoJuan Antonio In contemporary societies we are witnessing an expansion of the messages of human capital. These messages have as their central dimension idea of the self-entrepreneur
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The role of the agreement as a tool for management of property relations in cases of cross border marriages and civil unions/partnerships registered …

2021

The essay examines the role of the agreement as a tool for managing property relationships in crossborder marriages and registered partnerships, in light of EU Regulations 1103 and 1104 of 2016, on the property regimes of international married or registered couples. The main prerogative of such acts is the recognition of the parties? freedom to choose the court and the applicable law. The law governing the matrimonial property regimes, or the property consequences of registered partnerships, has universal scope. This agreement in the form envisaged, which is backed by the need for legal certainty and predictability of the applicable rules, means that the spouses, in family problems which ha…

with reference to the ?applicable law?and of common law systems which give effect to a moderate interpretation of the will of the courts. Go away. Cross-border marriages and registered partnershipsthe hard base on which the contractual structure provided for in the Regulation is builthas universal scope. This agreement in the form envisagedMatrimonios y parejas registradas trasfronterizaswhich strengthens the objectives of both civil law systemsmeans that the spousesautonomía contractual. 242 251which is backed by the need for legal certainty and predictability of the applicable rulesboth explicitly and implicitly. Thusare faced with a uniform system of rules on ?conflict? which can resolve them. Thereforeforo y ley aplicableor the property consequences of registered partnershipswhich open the way to a moderate interpretation of general clauses by the courts:CIENCIAS JURÍDICAS [UNESCO]Maria Gabriella The essay examines the role of the agreement as a tool for managing property relationships in crossborder marriages and registered partnershipsthe court and the applicable lawuniform systemcontractual autonomy.2386-4567 22661 Actualidad jurídica iberoamericana 587897 2021 15 8113560 The role of the agreement as a tool for management of property relations in cases of cross border marriages and civil unions/partnerships registered under the EU regulations nr. 1103 and 1104/2016. Rossisistema uniformein family problems which have cross-border implicationsUNESCO::CIENCIAS JURÍDICASthe contractual autonomy in this provision appears to be the first point of connection between the different systemson the property regimes of international married or registered couples. The main prerogative of such acts is the recognition of the parties? freedom to choose the court and the applicable law. The law governing the matrimonial property regimesRegulation 1103 provides ample scope for contractual autonomyin light of EU Regulations 1103 and 1104 of 2016
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La organización del trabajo por proyectos: La fábrica de la precariedad laboral

2019

The project-based organization, considered as a radical reorganization of work around one or more simultaneous projects, is nowadays widespread in large companies and public administrations. According to the managerial way of thinking, this system would be virtuous: by giving more autonomy to the employees in the act of production and by developing their skills through mobility and interdisciplinarity of work teams, it would be able to arouse their full commitment. This study confirms in some way how this opinion has been imposed, but at the expense of precarious working conditions, increasing the dedication of employees and silencing any form of criticism. The research is based on a review…

work organisationprecariousness 119 1241137-7038 8537 Arxius de sociologia 525290 2019 40 7038146 La organización del trabajo por proyectos: La fábrica de la precariedad laboral Goussardbut at the expense of precarious working conditionsby giving more autonomy to the employees in the act of production and by developing their skills through mobility and interdisciplinarity of work teams [this system would be virtuous]Lucie The project-based organizationorganización del trabajoincreasing the dedication of employees and silencing any form of criticism. The research is based on a review of the literature and 50 interviews with technicianshealthconsidered as a radical reorganization of work around one or more simultaneous projects:SOCIOLOGÍA [UNESCO]is nowadays widespread in large companies and public administrations. According to the managerial way of thinkingProject-based organizationthis system would be virtuous: by giving more autonomy to the employees in the act of production and by developing their skills through mobility and interdisciplinarity of work teamssaludUNESCO::SOCIOLOGÍAit would be able to arouse their full commitment. This study confirms in some way how this opinion has been imposedLa fábrica de la precariedad laboral Goussard [1137-7038 8537 Arxius de sociologia 525290 2019 40 7038146 La organización del trabajo por proyectos]precariedadwhere project-based organization is widespread. The links between this organization of work and precariousness are one of the results that stand out after the investigation. trabajo por proyectosengineers and industrial design executives working in a large company in the French automotive industry
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