Search results for " border"
showing 10 items of 142 documents
Intestinal cholesterol absorption: identification of different binding proteins for cholesterol and cholesterol absorption inhibitors in the enterocy…
2003
Absorption of cholesterol from the intestine is a central part of body cholesterol homeostasis. The molecular mechanisms of intestinal cholesterol absorption and the proteins mediating membrane transport are not known. We therefore aimed to identify the proteins involved in intestinal cholesterol absorption across the luminal brush border membrane of small intestinal enterocytes. By photoaffinity labeling using photoreactive derivatives of cholesterol and 2-azetidinone cholesterol absorption inhibitors, an 80-kDa and a 145-kDa integral membrane protein were identified as specific binding proteins for cholesterol and cholesterol absorption inhibitors, respectively, in the brush border membra…
Kinetics of zinc transport in vitro in rat small intestine and colon: interaction with copper.
2002
The present study was planned to investigate the kinetic transport of zinc, in the intact intestine of the rat, in order to establish if more than one transporter is involved as well as the existence of a preferent sector in the cation uptake. Using an in vitro technique, the influx of zinc across the brush border membrane in three sectors of the small intestine (proximal, mid and distal) and in the colon of the rat was measured at six different concentrations (from 0.0007 to 11 mM). The kinetic study showed that intestinal transport of zinc occurs by a saturable process in the small intestine. The K(m) value obtained in the proximal segment (10.78+/-4.40 mM) is clearly higher than those ob…
Emotional awareness and cognitive performance in borderline intellectual functioning young adolescents
2019
According to DSM-5 and ICD-10, borderline intellectual functioning (BIF) should not be classified properly as a disorder. However, BIF people may present relevant problems of adaptive functioning in several areas of daily activities, and they seem to be more vulnerable to mental diseases. Young adolescence may be considered a particular period for emotional information processing. The "own and others' emotions" awareness can play a crucial role in many daily life situations, such as decision making, interpersonal relationships, and decoding of facial expressions. On this background, a BIF young adolescents group underwent a neuropsychological assessment including emotional and cognitive dom…
Glucose/galactose malabsorption caused by a defect in the Na+/glucose cotransporter.
1991
Glucose/galactose malabsorption (GGM) is an autosomal recessive disease manifesting within the first weeks of life and characterized by a selective failure to absorb dietary glucose and galactose from the intestine. The consequent severe diarrhoea and dehydration are usually fatal unless these sugars are eliminated from the diet. Intestinal biopsies of GGM patients have revealed a specific defect in Na(+)-dependent absorption of glucose in the brush border. Normal glucose absorption is mediated by the Na+/glucose cotransporter in the brush border membrane of the intestinal epithelium. Cellular influx is driven by the transmembrane Na+ electrochemical potential gradient; thereafter the sugar…
Defective jejunal brush border membrane sodium/proton exchange in association with lethal familial protracted diarrhoea.
1990
The spectrum of clinical disease associated with specific defects in jejunal brush border membrane sodium/proton exchange is poorly defined and only two patients have been described so far. Jejunal brush border membrane transport studies were performed in a boy who presented with lethal familial protracted diarrhoea in the first few days of life. Using jejunal brush border membrane vesicles prepared from conventional jejunal biopsy specimens, initial sodium uptake under H+ gradient conditions was found to be only 6% of the mean control value. In contrast, sodium stimulated glucose uptake was normal. Our data confirm the importance of a congenital defect in this exchanger as a cause of sever…
Kā robežas ietekmē NATO ģimenes locekļu integrāciju uzņēmējvalstī
2020
Bakalaura darbā es koncentrējos gan uz fiziskajām, gan abstraktajām NATO robežām, kas ir ietekmējošie faktori NATO ģimeņu integrācijas procesā uzņemšanas valstī un organizācijas dalībnieku identitātes veidošanā. Es skatu kā abstraktās robežas, piemēram, valodas robežas, tiek konstruētas un uzturētas militārajā kontekstā. Analizējot dalībnieku intervijas, es uzsveru cilvēku pieredzes aspektus gan NATO robežās, gan ārpus tām, dalībnieku pašidentifikāciju, kā arī kultūru apvienošanos.
Congenital lower lip pits : Van der Woude syndrome
2018
The Van der Woude syndrome is a rare autosomal dominant development malformation characterized by a paramedian lip pits and /or sinuses or conical elevation of lower lip associated with cleft lip and or palate. These congenital lip pits usually appear clinically in the vermilion border of lip, with or without secretion. The critical region of VWS has been identified to be at Iq32 to 41 with high, but incomplete penetrance and variable expressivity. Therapeutic intervention is generally required for cosmetic reason or when recurrent inflammation is present. Dental surgeon should be aware of this syndrome, as it is associated with variety of other congenital malformation. van der woude syndro…
The landscape of strongholds
2016
La difesa dei territori ha offerto risultati straordinari alla formazione e alla trasformazione del territorio e del paesaggio, a volte con tratti spettacolari e dimensioni incredibili. La celebrazione del centenario dell’inizio della Prima guerra mondiale ha offerto lo spunto per una riflessione sulle ricadute indotte sul paesaggio dagli eventi bellici, e più in generale dalla realizzazione di strutture difensive e del loro rapporto con il paesaggio circostante. Territorial defence led to extraordinary results in terms of forming and transforming the territory and landscape, at times with spectacular sights and incredible sizes. The one hundred year anniversary since the beginning of the F…
DEFECTIVE JEJUNAL BRUSH BORDER Na+/H+ EXCHANGE IN LETHAL FAMILIAN PROTRACTED DIARRHOEA
1989
The clinical spectrum of disease associated with the recently described defect in jejunal brush border membrane (BBM) Na+/H+ exchange remains poorly defined. We describe a further, lethal case of protracted diarrhoea in a child from a family in whom 2 previous siblings died of protracted diarrhoea at 2 and 11 months. The patient, a boy, was born at term weighing 2.9 kg and was admitted at 6d with profuse watery diarrhoea, severe dehydration and metabolic acidosis. Parenteral nutrition was started but the diarrhoea persisted, and he developed severe necrotising enterocolitis requiring an ileostomy. A high-output secretory diarrhoea persisted during nil by mouth (ileostomy fluid mmol/l: Na+ 1…
Joseph Conrad-Korzeniowski, an English Writer with a Polish Soul: Joseph Conrad’s Polish Heritage
2018
The article presents a portrait of Joseph Conrad-Korzeniowski, an English writer with a Polish soul. Conrad—the last Polish Romantic—did not only manage to introduce Polish dreams and longings into English (and Western) literature, but also transformed the Polish experience into a universal one. Writing about exotic, faraway places, he disseminated myths concerning Polish national identity, chivalric tradition and the Polish Eastern Borderland atmosphere and ethos. Conrad, a very demanding writer, never presents ready-made answers, nor does he offer simple solutions to the problems of his protagonists. Moreover, everybody can understand Conrad in their own personal way, for he is perceived …