Search results for " box"

showing 10 items of 161 documents

ceRNA Network Regulation of TGF-β, WNT, FOXO, Hedgehog Pathways in the Pharynx of Ciona robusta

2021

The transforming growth factor-β (TGF-β) family of cytokines performs a multifunctional signaling, which is integrated and coordinated in a signaling network that involves other pathways, such as Wintless, Forkhead box-O (FOXO) and Hedgehog and regulates pivotal functions related to cell fate in all tissues. In the hematopoietic system, TGF-β signaling controls a wide spectrum of biological processes, from immune system homeostasis to the quiescence and self-renewal of hematopoietic stem cells (HSCs). Recently an important role in post-transcription regulation has been attributed to two type of ncRNAs: microRNAs and pseudogenes. Ciona robusta, due to its philogenetic position close to verte…

0301 basic medicineascidianpseudogenepseudogeneslcsh:ChemistryTransforming Growth Factor betaProtein Interaction MappingHomeostasisRNA-Seqlcsh:QH301-705.53' Untranslated RegionsSpectroscopyTissue homeostasisForkhead Box Protein O1Wnt signaling pathwayHigh-Throughput Nucleotide Sequencingvirus diseasesGeneral Medicinefemale genital diseases and pregnancy complicationsComputer Science ApplicationsCell biologyNGSStem cellTGF-βCell fate determinationBiologyCatalysisArticleInorganic ChemistryWNT03 medical and health sciencesmicroRNAAnimalsCell LineageHedgehog ProteinsTGF-Physical and Theoretical ChemistryMolecular BiologyHedgehogneoplasmsmiRNA030102 biochemistry & molecular biologyCompeting endogenous RNAOrganic ChemistryfungiComputational BiologyHematopoiesisWnt ProteinsMicroRNAs030104 developmental biologylcsh:Biology (General)lcsh:QD1-999Gene Expression RegulationImmune SystemPharynxFOXOCionaTransforming growth factorInternational Journal of Molecular Sciences
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3D Technology for the Artworks Handling

2022

In this study we present how to create a box for the transport of artworks put in place during the restauration of three polymateric sculpures made with trapanese technique called ‘Legno, Tela e Colla’. Thanks to 3D technology, we created a ‘digital twin’ of manufacts that allowed us to design and build supports and boxes for different uses. In this way, it was possible not to touch the artworks directly, so without risks for them, and to work even at a distance without the works, also in different places.

3D technology handling trapanese technique boxSettore ICAR/17 - DisegnoSettore CHIM/02 - Chimica Fisica
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La adopción abierta en el derecho español

2016

El reconocimiento del derecho del menor adoptado a mantener contactos o relaciones con sus familiares de origen y sus anteriores acogedores representa un nuevo modelo de adopción en el Derecho español, denominado “adopción abierta”, recientemente introducida por la Ley 26/2015, de 28 de julio, que reforma el sistema español de protección de la infancia y la adolescencia. La nueva regulación se inspira en el Derecho de otros países pero tiene precedentes en ciertas normas autonómicas españolas The recognition of the right of the adopted children to maintain contacts or relations with their families of origin and previous welcoming, represents a new model of adoption in the Spanish law, which…

:CIENCIAS JURÍDICAS [UNESCO]Cartas y comunicacionesMantenimiento de relaciones con la familia de origen por acuerdo judicialPost adoption contact orderOpen adoptionAuto de adopciónCiencias jurídicasDerecho de visitaUNESCO::CIENCIAS JURÍDICASAdopción abiertaRight of visitLetter-boxAdoption orderWelfare checklistContact boxCiencias jurídicas. GeneralidadesBienestar emocional del menor
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Ultradian rhythms in avoidance behavior of DBA mice

1994

This study investigates ultradian rhythm in avoidance behavior of mice, which may constitute a basic rest activity cycle (BRAC). Reaction times (RTs) of an avoidance response to a visual warning stimulus that preceded an electric shock were measured by the use of a computer-controlled shuttle box. The male naive DBA mice were brought to a criterion of 98% correct responses in numerous training sessions. For each subject, all the temporal sequences of the RTs in the trials following achievement of the criterion were examined with discrete Fourier transform. Periodograms were obtained from three sessions for each of the two animals in the first experiment and from 15 subjects in the second ex…

Activity CyclesMaleElectroshockmedicine.medical_specialtymedia_common.quotation_subjectExperimental and Cognitive PsychologyStimulus (physiology)Avoidance responseAudiologyRest activityDevelopmental psychologyMiceBehavioral NeuroscienceRhythmMice Inbred DBAShuttle boxAvoidance LearningReaction TimemedicineAnimalsPsychologyUltradian rhythmVigilance (psychology)media_commonPhysiology & Behavior
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Testicular fusocellular rhabdomyosarcoma as a metastasis of elbow sclerosing rhabdomyosarcoma: A clinicopathologic, immunohistochemical and molecular…

2010

Abstract Sclerosing rhabdomyosarcoma (SRMS) is an infrequent variant of rhabdomyosarcoma characterized by extensive intercellular hyaline fibrosis. We report the case of a 37 year-old male with a 9 × 6 cm SRMS on the right elbow. Histologically, the tumor showed an abundant extracellular hyaline matrix with extratumoral vascular emboli and microscopic foci of fusocellular embryonal rhabdomyosarcoma (FRMS) separated by a fibrotic band from the sclerosing areas. One year later the patient presented with a right intratesticular tumor of 1.2 × 0.8 cm, which was reported as pure FRMS. Immunohistochemically, SRMS was positive only for MyoD1 and Vimentin and negative for Myogenin and Desmin. Both …

AdultMalePathologymedicine.medical_specialtyHistologyTime FactorsVimentinCase ReportSoft Tissue NeoplasmsSclerosing rhabdomyosarcomaBiologyTranslocation GeneticPathology and Forensic MedicineMetastasisFatal OutcomeTesticular Neoplasmslcsh:PathologymedicineBiomarkers TumorElbowHumansRhabdomyosarcoma EmbryonalWhole Body ImagingRhabdomyosarcomaHyalineIn Situ Hybridization FluorescenceSclerosisChromosomes Human Pair 13Forkhead Box Protein O1MediastinumForkhead Transcription FactorsGeneral Medicinemedicine.diseasemusculoskeletal systemFibrosisImmunohistochemistrymedicine.anatomical_structureTreatment OutcomeChemotherapy Adjuvantbiology.proteinDesminEmbryonal rhabdomyosarcomaTomography X-Ray ComputedOrchiectomylcsh:RB1-214
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Ten novel mutations found in Aniridia.

1998

Aniridia (AN) is a sight-threatening congenital ocular disorder characterized by iris hypoplasia, corneal pannus, foveal and optic nerve hypoplasia, cataract formation, and glaucoma. In two-thirds of the patients, AN is inherited in an autosomal dominant fashion with almost complete penetrance but variable expression. The remaining cases are sporadic. Aniridia has been shown to be associated with mutations in the PAX6 gene, located on chromosome 11p13, telomeric to the Wilms' tumor predisposition gene (WT1). This paper describes 14 mutations in the PAX6 gene in patients with AN. Among these 14 mutations, 10 have been unpublished until now. They result most probably in haploinsufficiency and…

AdultMalegenetic structuresAdolescentPAX6 Transcription FactorDNA Mutational AnalysisMolecular Sequence DataBiologyPolymerase Chain ReactionVariable ExpressionGeneticsmedicineHumansPaired Box Transcription FactorsAmino Acid SequenceChildEye ProteinsGeneAniridiaGenetics (clinical)Polymorphism Single-Stranded ConformationalGeneticsHomeodomain ProteinsOptic nerve hypoplasiaInfantMiddle Agedmedicine.diseasePenetranceeye diseasesDNA-Binding ProteinsRepressor ProteinsAniridiaChild PreschoolMutationHomeoboxFemalesense organsPAX6HaploinsufficiencyTranscription FactorsHuman mutation
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The relationship between stocking eggs in boreal spawning rivers and the abundance of brown trout parr

2015

Abstract Stocking with eggs has been widely used as a management measure to support degraded salmonid stocks. In Finland, Atlantic salmon and both sea-migrating and lake-migrating brown trout are stocked as eggs, alevins, fry, parr, and smolt, whereas trout are also stocked as mature fish. The aim of this stocking is to improve catches and to support collapsed spawning stocks. We assessed the success of stocking with brown trout eggs in a study of 17 Finnish boreal forest rivers, of which 9 were subject to egg stocking. All rivers contained some naturally spawning trout. In 16 rivers, including non-stocking years and unstocked rivers, egg stocking did not increase the total (wild and stocke…

Alizarin redAquatic ScienceOceanographysurvivalBrown troutStockingotolithAbundance (ecology)medicineSalmo truttaegg pocketEcology Evolution Behavior and SystematicsOtolithegg boxEcologybiologyTaigabiology.organism_classificationFisheryTroutmedicine.anatomical_structureBorealalevinThreatened speciesta1181reddhenkiinjääminenstock managementICES Journal of Marine Science
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Polygyny and Breeding Success of Pied Flycatchers Nesting in Natural Cavities

1990

Many hole-nesting passerine birds accept, or even prefer, nest boxes. Hence most of our knowledge about the breeding biology, population dynamics, life-history evolution and so forth of such species comes from nest box studies. This, in some cases, might lead to erroneous conclusions. For example, breeding density in nest box areas may often be much higher than in the natural situation (e.g. von Haartman, 1971), possibly leading to unnatural density dependent effects. Furthermore, the use of nest boxes may reduce predation risks (e.g. Nilsson 1975, 1984 a,b, Moller 1989), while the routine procedure of cleaning boxes after each breeding season may reduce the number of parasites, thus affect…

Avian clutch sizeeducation.field_of_studyNestMate choicebiologyReproductive successEcologybiology.animalPopulationeducationNest boxPasserinePredation
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Variation in clutch size in relation to nest size in birds

2014

© 2014 The Authors. Nests are structures built to support and protect eggs and/or offspring from predators, parasites, and adverse weather conditions. Nests are mainly constructed prior to egg laying, meaning that parent birds must make decisions about nest site choice and nest building behavior before the start of egg-laying. Parent birds should be selected to choose nest sites and to build optimally sized nests, yet our current understanding of clutch size-nest size relationships is limited to small-scale studies performed over short time periods. Here, we quantified the relationship between clutch size and nest size, using an exhaustive database of 116 slope estimates based on 17,472 nes…

BREEDING SUCCESSAvian clutch sizeBiodiversité et EcologieSEXUAL SELECTIONPredationnatural holesNestTITS PARUS-MAJORBLUE TITSQL_671Original ResearchGEEcologyEcologyhole nestingSTURNUS-VULGARISFLYCATCHERS FICEDULAChemistryreaction normSexual selectioninternational1181 Ecology evolutionary biologyHole nestingHole nesting natural holes nest boxes reaction normnest boxeseducationta1172ZoologyBiologyIntraspecific competitionEcology and EnvironmentBiodiversity and EcologyClutchBiologyNest boxEcology Evolution Behavior and SystematicsNature and Landscape ConservationEkologi[ SDE.BE ] Environmental Sciences/Biodiversity and EcologyInterspecific competitionPIED FLYCATCHERSPASSERINE BIRDSHole nesting;natural holes;nest boxes;reaction normSettore AGR/11 - Entomologia Generale E Applicatata1181[SDE.BE]Environmental Sciences/Biodiversity and EcologyGREAT TITSZoologyTHERMAL CONDITIONSEcology and Evolution
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Providing a general framework about spin-off success factors in complex environments

2018

Spin-off organisations are the main vehicle for knowledge transfer from universities and/or high educational institutions (HEIs) to the economic system. Spin-off firms are complex phenomenon which requires particular conditions to its creation, survival and development. In the last decade, the scientific debate recognised the importance and the role of spin-off organisations, but the main factors and actors that impact on their creation, survival and development are not always clear. This paper aims to fill this gap, shedding light on this black box. In a first step, this research will identify the main 'success factors' for creation of spin-offs. In the second step, the relationship betwee…

Black box (phreaking)Knowledge managementOriginalitybusiness.industryPhenomenonmedia_common.quotation_subjectSuccess factorsScientific debateBusinessPractical implicationsKnowledge transfermedia_commonSpin-½International Journal of Markets and Business Systems
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