Search results for " brain"
showing 10 items of 985 documents
Profilo docente: Tra riflessività e narrazione. Un itinerario di ricerca con gli insegnanti in formazione a distanza
2021
Le ricerche sulla cognizione, sulla competenza metacognitiva e sul funzionamento del cervello non smettono di destare vivo interesse presso la comunità scientifica delle discipline educative specie in relazione alla necessità di integrare, in qualsiasi percorso didattico e/o formativo, l'irrinunciabile componente della riflessività su se stessi e sul proprio modus di relazione con la conoscenza. Gli approcci di tipo brain-based -“con riguardo alla tecnica del Brain-gym - e l'attività di narrazione“ declinata secondo la tipologia del Digital Storytelling "costituiscono gli assi portati della ricerca qui descritta, condotta con 268 corsisti frequentanti, in modalità a distanza, i moduli di Di…
La riflessività e il ‘cervello narrante': un percorso di ricerca con gli studenti universitari
2017
Le ricerche sulla cognizione, sulla competenza metacognitiva e sul funzionamento del cervello non smettono di destare vivo interesse presso la comunità scientifica delle discipline educative specie in rela-zione alla necessità di integrare, in qualsiasi percorso didattico e/o for-mativo, l’irrinunciabile componente della riflessività su se stessi e sul proprio modus di relazione con la conoscenza. Gli approcci di tipo brain-based – con riguardo alla tecnica del Brain-gym – e l’attività di narrazione – declinata secondo la tipologia del Digital Storytelling – costituiscono gli assi portati della ricerca qui descritta, condotta con 205 studenti del secondo anno del corso di laurea in Scienze …
NANOSTRUCTURED LIPID CARRIERS CONTAINING RILUZOLE AND PHARMACEUTICAL FORMULATIONS CONTAINING SAID PARTICLES
2008
The present invention concerns the preparation, the physical-chemical, technological and pharmaceutical characterization of Riluzole-loaded nanoparticle vectors. The chosen production technology permitted to obtain these systems in a reproducible way, with high yields and low costs. In particular, a novel formulation of Riluzole loaded into lipid nanoparticles was developed which is able to carry to the Central Nervous System a higher amount of drug in comparison with the free drug. In vivo results demonstrated that the administration on rats of these formulation permits to obtain a lower deposit of Riluzole in organs such as liver, spleen, heart and kidneys; the consequence is a reduction …
Universal newborn hearing screening in the Italian Region of Sicily in 2018
2021
We have clarified the role of Universal Neonatal Hearing Screening (UNHS) for both early diagnosis and rapid treatment in order to improve the prognosis of the deaf child and reduce patient management costs. Although in Sicily UNHS has been progressively implemented, there is scarce data in the literature on this matter. Therefore, the main objective was to collect in the year 2018 the following data: number of newborns screened for hearing loss, number of infants "referred" to transiently evoked otoacoustic emissions (TEOAE), number of infants with pathologic auditory brainstem response (ABR) and number of infants affected by permanent hearing loss.UNHS monitoring was conducted through the…
Xenon treatment improves short-term and long-term outcomes in a rodent model of traumatic brain injury
2018
When the brain goes diving: glial oxidative metabolism may confer hypoxia tolerance to the seal brain.
2009
Deep diving mammals have developed strategies to cope with limited oxygen availability when submerged. These adaptations are associated with an increased neuronal hypoxia tolerance. Brain neurons of the hooded seal Cysto- phora cristata remain much longer active in hypoxic condi- tions than those of mice. To understand the cellular basis of neuronal hypoxia tolerance, we studied neuroglobin and cy- tochrome c in C. cristata brain. Neuroglobin, a respiratory protein typically found in vertebrate neurons, displays three unique amino acid substitutions in hooded seal. However, these substitutions unlikely contribute to a modulation of O2 affinity. Moreover, there is no significant difference i…
Voxel-Based Morphomerty study in patients with amnestic Mild Cognitive Impairment and Alzheimer's Disease: population-based data from the Zabùt Aging…
2017
Aims and objectives Methods and materials Results Conclusion Personal information References
Nicotine-induced FGF-2 mRNA in rat brain is preserved during aging
2004
Indirect trophic actions of nicotine on brain during aging are suggested from observations describing nicotine as a cognitive enhancer, increasing vigilance and improving learning and memory, and both in vitro and in vivo models have demonstrated neuroprotective effects of nAChR agonists. Previously, we have reported that an acute intermittent (-)nicotine treatment significantly increases fibroblast growth factor-2 (FGF-2) mRNA and protein in several brain regions of rat brain. The present study was designed to analyse if nicotine-induced FGF-2 expression in the rat brain was preserved during aging. Using in situ hybridization and quantitative RNase protection assay the present paper report…
Dietary prevention of visual function and cognitive decline by omega-3 polyunsaturated fatty acids in Senescence Accelerated Mouse P8 (SAM P8)
2008
International audience; Purpose: : Neuronal tissues such as the brain and the retina contain elevated amounts of long-chain omega-3 polyunsaturated fatty acids (PUFAs) and particularly docosahexaenoic acid (DHA). DHA concentrations are known to decrease in the aging brain and are associated with cognitive decline. The senescence-accelerated mouse prone 8 (SAM P8) is a mouse model for aging that exhibits deficits in cognitive performances as well as alterations of retinal functionality (ARVO 2004 E-abstract 797). The aim of this study was to evaluate the effects of a dietary supplementation with DHA on mood, cognition and visual functionality of SAM P8 during aging. Methods: : SAM P8 mice we…
Altered host behaviour and brain serotonergic activity caused by acanthocephalans: evidence for specificity
2006
Manipulative parasites can alter the phenotype of intermediate hosts in various ways. However, it is unclear whether such changes are just by-products of infection or adaptive and enhance transmission to the final host. Here, we show that the alteration of serotonergic activity is functionally linked to the alteration of specific behaviour in the amphipodGammarus pulexinfected with acanthocephalan parasites.Pomphorhynchus laevisand, to a lesser extent,Pomphorhynchus tereticollisaltered phototactism, but not geotactism, inG. pulex, whereas the reverse was true forPolymorphus minutus. Serotonin (5-hydroxytryptamine, 5-HT) injected to uninfectedG. pulexmimicked the altered phototactism, but ha…