Search results for " c.c."

showing 10 items of 4655 documents

Tumor targeting of baculovirus displaying a lymphatic homing peptide.

2008

Background Tumor-associated cells and vasculature express attractive molecular markers for site-specific vector targeting. To attain tumor-selective tropism, we recently developed a baculovirus vector displaying the lymphatic homing peptide LyP-1, originally identified by ex vivo/in vivo screening of phage display libraries, on the viral envelope by fusion to the transmembrane anchor of vesicular stomatitis virus G-protein. Methods In the present study, we explored the specificity and kinetics of viral binding and internalization as well as in vivo tumor homing of the LyP-1 displaying virus to elucidate the applicability of baculovirus for targeted therapies. Results We demonstrated that th…

virusesmedia_common.quotation_subjectGenetic VectorsMice NudeBiologyPeptides CyclicVirus03 medical and health sciencesTransduction (genetics)Mice0302 clinical medicineViral envelopeViral Envelope ProteinsIn vivoTransduction GeneticCell Line TumorNeoplasmsDrug DiscoveryGeneticsAnimalsHumansTransgenesInternalizationMolecular BiologyGenetics (clinical)030304 developmental biologymedia_commonLymphatic Vessels0303 health sciencesBinding SitesMembrane GlycoproteinsGene Transfer TechniquesGenetic Therapybiology.organism_classificationMolecular biology3. Good healthCell biologyVesicular stomatitis virus030220 oncology & carcinogenesisMolecular MedicineBaculoviridaeEx vivoHoming (hematopoietic)The journal of gene medicine
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Conflicts in workplace in technology-mediated communication

2017

Konfliktit työyhteisön teknologiavälitteisessä vuorovaikutuksessa. Tämän tutkielman tavoitteena oli kuvata työntekijöiden havaintoja konflikteista, jotka ilmenivät työpaikkojen teknologiavälitteisessä vuorovaikutuksessa. Työntekijöiden havaintoihin pohjaten tutkielma pyrki kasvattamaan ymmärrystä työelämässä ja teknologiavälitteisessä vuorovaikutuksessa ilmenevistä konflikteista etsimällä vastauksia siihen, millaisia syitä, seurauksia ja lopputuloksia konflikteilla on työyhteisöjen teknologiavälitteisessä vuorovaikutuksessa. Konfliktien ja niiden hallintakeinojen ymmärtäminen on tärkeää työyhteisöille ja niissä toimiville työyhteisön jäsenille. Tutkielman menetelmänä käytettiin teoriasidonn…

vuorovaikutuscommunicationconflict managementtyöyhteisötkonfliktinhallintatechnology-mediated communicationviestintätekniikkaristiriidatconflict typeskonfliktinratkaisuconflict cyclework lifeverkkoviestintätyöelämäKvalitatiivinen sisällönanalyysi
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Public-private sector pay gaps over the business cycle :

2010

wage curvebusiness cycletalouskasvujulkinen talouspalkatsuhdannevaihtelutpublic sector payjulkinen sektori
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Lagrangian matches between observations from aircraft, lidar and radar in an orographic warm conveyor belt

2020

Warm conveyor belts (WCBs) are important airstreams in extratropical cyclones, often leading to the formation of intense precipitation and the amplification of upper-level ridges. This study presents a case study that involves aircraft, lidar and radar observations in a WCB ascending from western Europe towards the Baltic Sea during the Hydrological Cycle in the Mediterranean Experiment (HyMeX) and T-NAWDEX-Falcon in October 2012, a preparatory campaign for the THORPEX North Atlantic Waveguide and Downstream Impact Experiment (T-NAWDEX). Trajectories were used to link different observations along the WCB, that is, to establish so-called Lagrangian matches between observations. To this aim, …

warm conveyor beltLidar010504 meteorology & atmospheric sciencesAtmosphärische SpurenstoffeOrographyInflowtracer01 natural sciencesFalconTroposphereobservationsClimatologyExtratropical cycloneOutflowPrecipitationWater cycleWolkenphysikGeology0105 earth and related environmental sciencesOrographic lift
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Synergistic effect of W incorporation and pulsed current mode on wear and tribocorrosion resistance of coatings grown by plasma electrolytic oxidatio…

2019

Ceramic coatings were grown by plasma electrolytic oxidation on 7075 Al alloy using unipolar and bipolar pulsed current waveforms with 20 and 40% cathodic duty cycles, from a silicate-based bath without and with the addition of Na2WO4. Pancake-like morphology was dominant on the coatings grown by unipolar waveform, while the bipolar waveforms promoted volcano-like morphology, increased the roughness of the coating surface and the formation of more compact layers. The coatings produced using the bipolar waveforms provided higher resistances toward both tribocorrosion and dry sliding conditions, while further improvement was achieved by the presence of tungsten. The coatings produced in tungs…

wearMaterials sciencePolymers and PlasticsTribocorrosionAlloyMetallurgyMetals and AlloysPlasma electrolytic oxidationengineering.materialtribocorrosionbipolar waveformSurfaces Coatings and FilmsElectronic Optical and Magnetic MaterialsBiomaterialschemistry.chemical_compoundTungstatechemistrytungstateduty cycleengineeringCurrent mode7075 Al alloy
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Lagrangian matches between observations from aircraft, lidar and radar in a warm conveyor belt crossing orography

2021

Warm conveyor belts (WCBs) are important airstreams in extratropical cyclones, often leading to the formation of intense precipitation and the amplification of upper-level ridges. This study presents a case study that involves aircraft, lidar and radar observations in a WCB ascending from western Europe towards the Baltic Sea during the Hydrological Cycle in the Mediterranean Experiment (HyMeX) and T-NAWDEX-Falcon in October 2012, a preparatory campaign for the THORPEX North Atlantic Waveguide and Downstream Impact Experiment (TNAWDEX). Trajectories were used to link different observations along the WCB, that is, to establish so-called Lagrangian matches between observations. To this aim, a…

wind fieldformation mechanismorographic effectboundary layerhydrological cycleextratropical cycloneensemble forecastingairborne surveytroposphereLagrangian analysisatmospheric dynamicsairflowlidarradar
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Bacterial communities in stratified humic lakes

2012

yhteisörakennelämpötilakerrostuneisuushiilihiilitasebacterial communityhumusjärvetbakteeriyhteisötgreenhouse gasnutrientshumic lakecarbon cycle454 pyrosequencingmetsäjärvetravinnepitoisuushiilipitoisuus
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Introduire un dispositif de renforcement disciplinaire en 1ère année universitaire permet-il aux étudiants d'obtenir de meilleures notes ?

2014

Avec le Plan Réussite en Licence (PRL), de nouveaux dispositifs d'aides à la réussite ont été expérimentés au sein des universités françaises. Or, l'étude de l'efficacité de ces dispositifs demeure peu développée, mis à part la méthodologie du travail universitaire (Coulon, 2005) ou le tutorat (Danner, 2000). Il est ainsi difficile d'identifier quel type de mesure semble le plus approprié pour agir le plus efficacement sur la réussite des étudiants, ne serait-ce que parce que peu de recherches se concentrent sur les questions d'apprentissage dans l'enseignement supérieur français (Fave-Bonnet et Clerc, 2001). L'ambition de cette communication est de mesurer les effets d'un nouveau type de d…

Évaluation des mesures éducatives[SHS.EDU]Humanities and Social Sciences/Education[SHS.EDU] Humanities and Social Sciences/EducationÉtudes universitaires[ SHS.EDU ] Humanities and Social Sciences/EducationAide à la réussiteSupérieur premier cycle
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Rücktitelbild: Water Structure Recovery in Chaotropic Anion Recognition: High-Affinity Binding of Dodecaborate Clusters to γ-Cyclodextrin (Angew. Che…

2015

γ cyclodextrinChaotropic agentHigh affinity bindingChemistryDodecaboratePolymer chemistryGeneral MedicineIonAngewandte Chemie
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Back Cover: Water Structure Recovery in Chaotropic Anion Recognition: High-Affinity Binding of Dodecaborate Clusters to γ-Cyclodextrin (Angew. Chem. …

2015

γ cyclodextrinChaotropic agentHofmeister seriesHigh affinity bindingChemistryINTInorganic chemistryDodecaborateSupramolecular chemistryGeneral ChemistryMedicinal chemistryCatalysisIonAngewandte Chemie International Edition
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