Search results for " cannabinoid"

showing 3 items of 163 documents

Characterization of the synthetic cannabinoid MDMB-CHMCZCA

2016

The synthetic cannabinoid MDMB-CHMCZCA was characterized by various spectroscopic techniques including NMR spectroscopy and tandem mass spectrometry. The synthetic sample was found to be of S-configuration by VCD spectroscopy and comparison of the data with DFT calculations, while ECD spectroscopy was found to be inconclusive in this case. The enantiomeric purity of samples from test purchases and police seizures was assessed by a self-developed chiral HPLC method.

medicine.medical_treatmentNPS010402 general chemistryTandem mass spectrometry01 natural sciencesFull Research Paperlcsh:QD241-441lcsh:Organic chemistrymedicinelcsh:Sciencechiral HPLCSpectroscopyChromatographyChemistry010401 analytical chemistryOrganic ChemistryNuclear magnetic resonance spectroscopy0104 chemical sciencesCharacterization (materials science)Chiral column chromatographyChemistryVCD spectroscopyECD spectroscopylcsh:QCannabinoidEnantiomersynthetic cannabinoidsBeilstein Journal of Organic Chemistry
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Effects of cannabinoids on spontaneous mechanical activity of mouse ileal longitudinal muscle.

2007

mouse ileum cannabinoid receptors Ach
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The CANNA-TICS Study Protocol: A Randomized Multi-Center Double-Blind Placebo Controlled Trial to Demonstrate the Efficacy and Safety of Nabiximols i…

2020

Background: Gilles de la Tourette syndrome (TS) is a chronic neuropsychiatric disorder characterized by motor and vocal tics. First-line treatments for tics are antipsychotics and tic-specific behavioral therapies. However, due to a lack of trained therapists and adverse events of antipsychotic medication many patients seek alternative treatment options including cannabis. Based on the favorable results obtained from case studies on different cannabis-based medicines as well as two small randomized controlled trials using delta-9-tetrahydrocannabinol (THC), we hypothesize that the cannabis extract nabiximols can be regarded as a promising new and safe treatment strategy in TS.Objective: To …

tourette syndromemedicine.medical_specialtyTHCTicslcsh:RC435-571NabiximolsPlacebo-controlled studynabiximolsPlaceboTourette syndromelaw.inventionStudy Protocol03 medical and health sciencescannabidioltetrahydrocannabinolcannabinoids0302 clinical medicineRandomized controlled triallawInternal medicinelcsh:Psychiatrymental disordersmedicinechronic tic disorderPsychiatrybusiness.industryticsnabiximols ; tetrahydrocannabinol ; cannabidiol ; chronic tic disorder ; tourette syndrome ; THC ; tics ; Tourette-Syndrom ; cannabinoidsmedicine.disease030227 psychiatryClinical trialPsychiatry and Mental healthChronic Tic Disorderbusiness030217 neurology & neurosurgerymedicine.drugFrontiers in Psychiatry
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