Search results for " cardiac"

Valor de la resonancia magnética con realce tardío de gadolinio en el diagnóstico etiológico de la insuficiencia cardiaca con disfunción sistólica de…

2013

La insuficiencia cardiaca constituye un problema de salud y de gestión de los recursos sanitarios de primer orden. Se estima que la prevalencia de insuficiencia cardiaca sintomática en la población general europea oscila entre el 0.4-2%. El diagnóstico preciso del síndrome de insuficiencia cardiaca por medios exclusivamente clínicos es dificultoso y muchas veces inadecuado sobre todo en mujeres, ancianos y obesos20. La insuficiencia cardiaca asociada a miocardiopatía dilatada idiopática o a miocardiopatía isquémica puede ser clínicamente indistinguible. Los síntomas de angina y los factores de riesgo generalmente asociados a la enfermedad coronaria no son exclusivos ni constantes, además, l…

Biomarcadores en hipertensión pulmonar de causa cardiaca izquierda. Valor diagnóstico y pronóstico.

2015

La hipertensión pulmonar (HP) debida a enfermedad del corazón izquierdo es una patología prevalente, grave y asociada a importante morbilidad y mortalidad, sobre todo cuando produce un deterioro de la función ventricular derecha. Dentro de esta enfermedad, existen varios tipos según la respuesta del lecho vascular pulmonar. Se asume que en la HP pasiva se inicia una disfunción endotelial que puede progresar hacia una hiperplasia vascular con grave repercusión sobre el ventrículo derecho y sin posibilidad de regresión. Actualmente, para el diagnóstico de HP es indispensable un cateterismo cardíaco derecho causante de morbilidad e incluso mortalidad. Lo que se pretende con este proyecto es in…

Association between ideal cardiovascular health and risk of sudden cardiac death and all-cause mortality among middle-aged men in Finland

2021

Background Strong associations have been demonstrated between the American Heart Association’s cardiovascular health (CVH) metrics and various cardiovascular outcomes, but the association with sudden cardiac death (SCD) is uncertain. We examined the associations between these CVH metrics and the risks of SCD and all-cause mortality among men in Finland. Methods and results We used the prospective population-based Kuopio Ischaemic Heart Disease cohort study, which consists of men between 42 and 60 years of age at baseline. CVH metrics were computed for 2577 men with CVH scores at baseline ranging from 0 to 7, categorized into CVH scores of 0–2 (poor), 3–4 (intermediate) and 5–7 (ideal). Mult…

Sleep Duration and Risk of Fatal Coronary Heart Disease, Sudden Cardiac Death, Cancer Death, and All-Cause Mortality

2018

Background: Sleep duration has been shown to be associated with all-cause mortality, however its relationship with cause-specific fatal events remains uncertain. We examined the relationship between sleep duration and risk of fatal coronary heart disease (CHD), sudden cardiac death, cancer related death and all-cause mortality. Methods Sleep duration was self-reported at baseline examinations performed between March 20, 1984 and December 5, 1989 in 2,361 men aged 42-61 years old from the Kuopio Ischemic Heart Disease study. Of these 1734 (73.4%) men were free from CHD and cancer at baseline. Results: A total of 802 all cause deaths, 202 fatal coronary heart disease events, 141 sudden cardia…

Coronary artery fistulas: symptoms may not correlate to size. An emblematic case and literature review

2015

<p>Coronary artery fistulas are rare anatomic abnormalities of the coronary arteries present in 0.002% of the general population and represent 14% of all anomalies of coronary arteries. Their clinical relevance focuses mainly on the mechanism of "coronary steal phenomenon”, causing myocardial functional ischemia even in the absence of stenosis, hence common symptoms are angina or dyspnea. Small size fistulas are mostly asymptomatic and have excellent prognosis if managed medically with regular follow-up consisting also in echocardiography every 2-5 years. Big-sized and symptomatic fistulas, on the contrary, should undergo invasive closure, either with a transcatheter approach or with …

Qualitative and Quantitative Analysis of Cardiac Progenitor Cells in Cases of Myocarditis and Cardiomyopathy

2018

We aimed to identify and quantify CD117+ and CD90+ endogenous cardiac progenitor cells (CPC) in human healthy and diseased hearts. We hypothesize that these cells perform a locally acting, contributing function in overcoming medical conditions of the heart by endogenous means. Human myocardium biopsies were obtained from 23 patients with the following diagnoses: Dilatative cardiomyopathy (DCM), ischemic cardiomyopathy (ICM), myocarditis, and controls from healthy cardiac patients. High-resolution scanning microscopy of the whole slide enabled a computer-based immunohistochemical quantification of CD117 and CD90. Those signals were evaluated by Definiens Tissue Phenomics® Technology. Co-loca…

Mediterranean diet impact on cardiovascular diseases: a narrative review

2017

Cardiovascular disease (CVD) accounts for more than 17 million deaths per year worldwide. It has been estimated that the influence of lifestyle on CVD mortality amounts to 13.7% for smoking, 13.2% for poor diet, and 12% for inactive lifestyle. These results deeply impact both the healthy status of individuals and their skills in working. The impact of CVD on productivity loss accounts for the 24% in total costs for CVD management. Mediterranean diet (MedD) can positively impact on natural history of CVD. It is characterized by a relatively high consumption of inexpensive and genuine food such as cereals, vegetables, legumes, nuts, fish, fresh fruits, and olive oil as the principal source of…

Out-of-hospital cardiac arrest during the COVID-19 era: The importance to fight against fear

2021

The challenge of laypeople cardio-pulmonary resuscitation training during and after COVID-19 pandemic.

2020

“Ultra-sensitive” cardiac troponins: Requirements for effective implementation in clinical practice

2018

The measurement of cardiac troponins, either cardiac troponin I or T, has become the culprit of clinical decision making in patients with suspected acute coronary syndrome (ACS), especially in those with non-ST elevation myocardial infarction (NSTEMI). The leading analytical mainstays of cardiac troponin immunoassays include the limit of blank (LoB), limit of detection (LoD), functional sensitivity, the 99th percentile of a healthy reference population, along with the percentage of “ostensibly healthy” subjects displaying measurable values 50% in the general healthy population. The very recent commercialization of methods with further improved analytical sensitivity (i.e., “ultra-sensitive”…