Search results for " cardiac"

showing 10 items of 523 documents

Usefulness of longitudinal systolic strain and delayed enhancement cardiac magnetic resonance in depicting risk of supraventricular arrythmias in pat…

2022

Background: Myocarditis have variable clinical presentation, evolution and prognosis. Aim of our study was to evaluate the value of speckle tracking echocardiography and cardiac magnetic resonance (CMR) in the short-term prediction of supraventricular arrhythmias (SVA) in patients with acute myocarditis. Methods: Seventy patients (mean age 31±14 years old) with acute myocarditis and preserved left ventricular ejection fraction (LVEF) were enrolled. Longitudinal systolic strain (LS) of the left ventricle (LV), mechanical dispersion (MD) and CMR with quantitative measurement of delayed enhancement (DE) were performed in a subset of 43 patients. Logistic regression and ROC analysis were used t…

AdultMagnetic Resonance SpectroscopyAdolescentarrhythmias cardiac magnetic resonance global longitudinal strain myocarditis Adolescent Adult AdultArrhythmias CardiacHumans Magnetic Resonance Imaging Cine Magnetic Resonance Spectroscopy Middle Aged Stroke VolumeMagnetic Resonance Imaging CineArrhythmias CardiacStroke VolumeMiddle AgedVentricular Function LeftMyocarditisVentricular Dysfunction LeftYoung AdultHumansRadiology Nuclear Medicine and imagingCardiology and Cardiovascular MedicineEchocardiography
researchProduct

A semi-automatic approach for epicardial adipose tissue segmentation and quantification on cardiac CT scans

2019

Abstract Many studies have shown that epicardial fat is associated with a higher risk of heart diseases. Accurate epicardial adipose tissue quantification is still an open research issue. Considering that manual approaches are generally user-dependent and time-consuming, computer-assisted tools can considerably improve the result repeatability as well as reduce the time required for performing an accurate segmentation. Unfortunately, fully automatic strategies might not always identify the Region of Interest (ROI) correctly. Moreover, they could require user interaction for handling unexpected events. This paper proposes a semi-automatic method for Epicardial Fat Volume (EFV) segmentation a…

AdultMale0301 basic medicineComputer scienceAdipose tissueHealth InformaticsCalcium score scans; Cardiac adipose tissue quantification; Coronary computed tomography angiography scans; Epicardial fat volume; Fat density quartiles; Semi-automatic segmentationFat density quartilesCorrelation03 medical and health sciencesComputer-AssistedDeep Learning0302 clinical medicineFat density quartileRegion of interestImage Interpretation Computer-AssistedCalcium score scansHumansSegmentationCalcium score scans; Cardiac adipose tissue quantification; Coronary computed tomography angiography scans; Epicardial fat volume; Fat density quartiles; Semi-automatic segmentation; Adipose Tissue; Adult; Algorithms; Deep Learning; Female; Humans; Image Interpretation Computer-Assisted; Male; Middle Aged; Pericardium; Tomography X-Ray ComputedImage InterpretationTomographyEpicardial fat volumeSemi-automatic segmentationbusiness.industryCalcium score scanPattern recognitionRepeatabilityMiddle AgedCoronary computed tomography angiography scansCoronary computed tomography angiography scanX-Ray ComputedComputer Science Applications030104 developmental biologyAdipose TissueCardiac adipose tissue quantificationQuartileEpicardial adipose tissueFemaleSemi automaticArtificial intelligenceTomography X-Ray ComputedSettore MED/36 - Diagnostica Per Immagini E RadioterapiabusinessPericardiumAlgorithms030217 neurology & neurosurgeryComputers in Biology and Medicine
researchProduct

Anatomical features and clinical correlations in Caucasian patients with definite arrhythmogenic right ventricular dysplasia/cardiomyopathy.

2014

AIM: Arrhythmogenic right ventrticular dysplasia/cardiomyopathy (ARVD/C) is an inherited cardiomyopathy characterized by fibrofatty replacement and a high risk of ventricular arrhythmias (VA) and sudden cardiac death (SCD). The aim of the present investigation is to examine the pathological profile and the clinical correlations in a group of ARVD/C patients. METHODS: We conducted a multicenter study evaluating 47 patients (31 men; mean age 37±14 years) with definite ARVD/C. Diagnosis was established according to the actual clinicomorphologic criteria at autopsy or clinically. We divided the study population in 2 different groups. First group included 28 alive patients and the second 19 pati…

AdultMaleAdolescentEuropean Continental Ancestry GroupLeftAge FactorsAdolescent; Adult; Age Factors; Aged; Arrhythmogenic Right Ventricular Dysplasia; Death Sudden Cardiac; European Continental Ancestry Group; Humans; Male; Middle Aged; Retrospective Studies; Ventricular Dysfunction Left; Young AdultMiddle AgedSettore MED/11 - Malattie Dell'Apparato CardiovascolareSuddenWhite PeopleDeathVentricular Dysfunction LeftYoung AdultDeath Sudden CardiacVentricular DysfunctionHumansCardiomyopathies - Death sudden - Young adult - ExerciseCardiacArrhythmogenic Right Ventricular DysplasiaAgedRetrospective StudiesMinerva cardioangiologica
researchProduct

[Cardiac arrhythmias in hypertensive subjects with and without left ventricular hypertrophy compared to the circadian profile of the blood pressure].

1990

To evaluate possible correlations between cardiac arrhythmias and circadian pattern of blood pressure (BP) and of heart rate (HR), we studied 2 groups of 20 males with stable arterial hypertension of mild to moderate entity, with (Group I) or without (Group II) left ventricular hypertrophy (LVH). In patients with LVH the mean age (56 vs 46 years), the duration of the hypertensive state (48.1 vs 15.7 months), the thickening of interventricular septum (IVS; 13.7 vs 9.6 mm) and of the posterior wall of the left ventricle (13.2 vs 9.2 mm) and the mass of LV (149.8 vs 99.7 g/m2) were significantly greater (p less than 0.01). On the contrary, the 2 groups did not show significant differences conc…

AdultMaleAdult Aged Arrhythmias Cardiac/physiopathology* Blood Pressure/physiology* Cardiomegaly/physiopathology* Circadian Rhythm/physiology* Electrocardiography Humans Hypertension/physiopathology* Male Middle Aged LinkOutSettore MED/09 - Medicina InternaArrhythmias CardiacBlood PressureCardiomegalyMiddle AgedSettore MED/11 - Malattie Dell'Apparato CardiovascolareCircadian RhythmElectrocardiographyHypertensionHumansAgedCardiologia (Rome, Italy)
researchProduct

Lorcainide. I. Saturable presystemic elimination.

1979

AdultMaleBenzeneacetamidesAdministration OralPharmacologyHepatic VeinsIn Vitro TechniquesPulmonary ArteryLorcainidePiperidinesMedicineHumansPharmacology (medical)Aorta AbdominalAortaAgedPharmacologybusiness.industryArrhythmias CardiacBlood ProteinsMiddle AgedBloodInjections IntravenousAcetanilidesFemalebusinessAnti-Arrhythmia Agentsmedicine.drugProtein BindingClinical pharmacology and therapeutics
researchProduct

Genome-Wide Association Studies of the PR Interval in African Americans.

2011

The PR interval on the electrocardiogram reflects atrial and atrioventricular nodal conduction time. The PR interval is heritable, provides important information about arrhythmia risk, and has been suggested to differ among human races. Genome-wide association (GWA) studies have identified common genetic determinants of the PR interval in individuals of European and Asian ancestry, but there is a general paucity of GWA studies in individuals of African ancestry. We performed GWA studies in African American individuals from four cohorts (n = 6,247) to identify genetic variants associated with PR interval duration. Genotyping was performed using the Affymetrix 6.0 microarray. Imputation was p…

AdultMaleCancer ResearchMuscle ProteinsSingle-nucleotide polymorphismGenome-wide association studyQH426-470030204 cardiovascular system & hematologyBiologyGenetics and Genomics/Complex TraitsPolymorphism Single NucleotideSodium ChannelsWhite PeopleNAV1.5 Voltage-Gated Sodium ChannelNAV1.8 Voltage-Gated Sodium Channel03 medical and health sciencesElectrocardiography0302 clinical medicineAsian PeopleCardiovascular Disorders/Arrhythmias Electrophysiology and PacingGeneticsSNPHumansCardiac and Cardiovascular SystemsPR intervalInternational HapMap ProjectMyeloid Ecotropic Viral Integration Site 1 ProteinMolecular BiologyGenotypingGenetics (clinical)Ecology Evolution Behavior and Systematics030304 developmental biologyAgedGeneticsHomeodomain Proteins0303 health sciencesArrhythmias CardiacHeart-rate;Atherosclerosis risk; Genetic-analysis; Common variants; Design; Populations; Objectives; Conduction; Disease; TwinsMiddle AgedNeoplasm ProteinsMinor allele frequencyBlack or African AmericanAtrioventricular NodeFemaleT-Box Domain ProteinsImputation (genetics)Research ArticleGenome-Wide Association Study
researchProduct

Serial echocardiographic left ventricular ejection fraction measurements: A tool for detecting thalassemia major patients at risk of cardiac death

2013

Cardiac damage remains a major cause of mortality among patients with thalassemia major. The detection of a lower cardiac magnetic resonance T2* (CMR-T2*) signal has been suggested as a powerful predictor of the subsequent development of heart failure. However, the lack of worldwide availability of CMR-T2* facilities prevents its widespread use for follow-up evaluations of cardiac function in thalassemia major patients, warranting the need to assess the utility of other possible procedures. In this setting, the determination of left ventricular ejection fraction (LVEF) offers an accurate and reproducible method for heart function evaluation. These findings suggest a reduction in LVEF≥7%, ov…

AdultMaleCardiac function curvemedicine.medical_specialtyHeart diseaseThalassemiaThalassemia major Left ventricular ejection fraction (LVEF) Chelation Echocardiography Cardiac magnetic resonance T2*Young AdultInternal medicinemedicineHumansMolecular BiologySurvival analysisModels StatisticalEjection fractionbusiness.industrybeta-ThalassemiaStroke VolumeCell BiologyHematologyStroke volumemedicine.diseaseClinical trialDeath Sudden CardiacROC CurveEchocardiographyHeart failurecardiovascular systemCardiologyMolecular MedicineFemalebusinessBlood Cells, Molecules, and Diseases
researchProduct

Cerebral oxygen saturation and cardiac output during anaesthesia in sitting position for neurosurgical procedures: a prospective observational study.

2016

Abstract Background Neurosurgical operations in the dorsal cranium often require the patient to be positioned in a sitting position. This can be associated with decreased cardiac output and cerebral hypoperfusion, and possibly, inadequate cerebral oxygenation. In the present study, cerebral oxygen saturation was measured during neurosurgery in the sitting position and correlated with cardiac output. Methods Perioperative cerebral oxygen saturation was measured continuously with two different monitors, INVOS® and FORE-SIGHT®. Cardiac output was measured at eight predefined time points using transoesophageal echocardiography. Results Forty patients were enrolled, but only 35 (20 female) were …

AdultMaleCardiac outputmedicine.medical_specialtyDecreased cardiac outputCerebral oxygen saturationSittingNeurosurgical ProceduresPatient Positioning03 medical and health sciences0302 clinical medicine030202 anesthesiologymedicineHumansAnesthesiaArterial PressureProspective StudiesCardiac OutputAgedbusiness.industryBrain030208 emergency & critical care medicinePerioperativeMiddle AgedOxygenOxygen Saturation MeasurementAnesthesiology and Pain MedicineBlood pressureAnesthesiaFemaleNeurosurgerybusinessBritish journal of anaesthesia
researchProduct

Undetected coronary artery disease in apparently healthy athletes

2019

UEM1901 5.864 JCR (2019) Q1, 18/138 Cardiac & Cardiovascular Systems 1.459 SJR (2019) Q1, 58/362 Cardiology and Cardiovascular Medicine; Q2, 36/104 Epidemiology No data IDR 2019 UEM

AdultMaleCoronary angiographymedicine.medical_specialtyEpidemiologyHealth StatusEnfermedad cardiovascularMEDLINECoronary Artery DiseaseCoronary AngiographyCoronary artery diseaseYoung AdultRisk FactorsAtletaInternal medicineHumansMedicineYoung adultcoronary artery disease athletes sportbiologybusiness.industryAthletesCoronary arteriosclerosisAtletasbiology.organism_classificationmedicine.diseaseDeath Sudden CardiacAthletesCardiologyFemaleCardiopatía coronariasportCardiology and Cardiovascular MedicinebusinessEuropean Journal of Preventive Cardiology
researchProduct

Information transfer in QT-RR dynamics: Application to QT-correction

2018

ABSTRACTThe relation between the electrical properties of the heart and the beating rate is essential for the heart functioning. This relation is central when calculating the “corrected QT interval” — an important measure of the risk of potentially lethal arrhythmias. We use the transfer entropy method from information theory to quantitatively study the mutual dynamics of the ventricular action potential duration (the QT interval) and the length of the beat-to-beat (RR) interval. We show that for healthy individuals there is a strong asymmetry in the information transfer: the information flow from RR to QT dominates over the opposite flow (from QT to RR), i.e. QT depends on RR to a larger e…

AdultMaleInformation transfermedicine.medical_specialtyCorrection methodEntropyHeart Ventricles0206 medical engineeringAction Potentialslcsh:Medicine02 engineering and technology030204 cardiovascular system & hematology3121 Internal medicine114 Physical sciencesQT intervalArticleElectrocardiography03 medical and health sciences0302 clinical medicineHeart RateLääketieteen bioteknologia - Medical biotechnologyInternal medicinemedicineHumanslcsh:ScienceAgedMathematicsBeating rateMultidisciplinarylcsh:RSisätaudit - Internal medicineCorrected qtArrhythmias CardiacHeartMiddle Aged020601 biomedical engineeringHealthy individualsCardiologyFemalelcsh:QTransfer entropy3111 Biomedicine030217 neurology & neurosurgeryScientific Reports
researchProduct