Search results for " casein"
showing 10 items of 26 documents
Hydrolyzed infant formula and early β-cell autoimmunity: a randomized clinical trial.
2014
Importance The disease process leading to clinical type 1 diabetes often starts during the first years of life. Early exposure to complex dietary proteins may increase the risk of β-cell autoimmunity in children at genetic risk for type 1 diabetes. Extensively hydrolyzed formulas do not contain intact proteins. Objective To test the hypothesis that weaning to an extensively hydrolyzed formula decreases the cumulative incidence of diabetes-associated autoantibodies in young children. Design, Setting, and Participants A double-blind randomized clinical trial of 2159 infants with HLA-conferred disease susceptibility and a first-degree relative with type 1 diabetes recruited from May 2002 to Ja…
Mechanical and barrier properties of extruded film made from sodium and calcium caseinates
2014
Abstract Over the past few years, much interest has been placed into the investigation of increased barrier and mechanical properties of protein films via a multitude of approaches. Generally, these techniques involve modifications of interactions among protein molecules, such as ionic crosslinking using divalent ions. To evaluate the crosslinking effect of Ca 2+ cations, films were made from calcium caseinate (CaCAS) and/or sodium caseinate (NaCAS). The production of caseinate thin films was carried out in two steps: first thermoplastic pellets were made using a co-rotating twin-screw extruder, then they were transformed into thin films (60 μm) using a classical film blowing machine. Tensi…
Effect of Caseinophosphopeptides from αs- and β-Casein on Iron Bioavailability in HuH7 Cells
2015
International audience; Two pools of caseinophosphopeptides (CPPs) obtained from αs- and β-casein fractions (α-CPPs and β-CPPs) were characterized. A total of 16 CPPs were identified in the α-CPPs pool, 9 of them derived from αs1-casein and 7 from αs2-casein. A total of 18 CPPs were identified in the β-CPPs pool. Four of the identified CPPs contained the characteristic phosphoseryl-glutamic acid cluster SpSpSpEE. Calcein assay was used to compare the iron-binding capacity of the α- and β-CPPs pools. At the concentration of 12.5 μM CPPs used in the iron bioavailability assays, β-CPPs pools show greater iron-binding capacity than α-CPPs pools. HuH7 human hepatoma cells show many differentiate…
Effetti della dieta sul profilo acidico del latte di capre con diverso genotipo per l’αs1-CN.
2013
ASSOCIATION BETWEEN THE POLYMORPHISM AT CASEIN LOCI AND MILK FATTY ACID COMPOSITION IN GIRGENTANA GOATS
2013
composition is an important trait for the goat dairy industry because of its influence on cheese yield and the organoleptic properties of dairy products (Chilliard et al., 2003). Goat milk is particularly rich in saturated fatty acids (SFA) whereas monounsaturated (MUFA) and polyunsaturated (PUFA) FA are less abundant (Fontecha et al., 2000).The aim of this work was to provide new data to better understand the influence of polymorphism at casein loci on fatty acid profile in Girgentana goat milk. One hundred lactating Girgentana goats, homogeneous for milk production, days of lactation, body weight and diet were used. The procedure was developed using individual raw milk samples, collected …
Haplotypes of Single Nucleotide Polymorphisms (SNPs) in casein loci of Girgentana goats explain isoelectrofocusing results.
2006
Goat milk, cheese and yoghurt offer an alternative to cow milk products. In Sicily one of the important goat breeds reared is the Girgentana. Traditionally the milk from Girgentana goats was used for nourishment of infants and elderly. Recently, the Girgentana breed has been in decline. This of concern, as the Girgentana may carry unique milk protein genetic variants. If health benefits of Girgentana goat milk is proven, then increasing production from this population will be of great interest. The most abundant proteins in goat milk, as in other milks, are the caseins, αS1-, β-, αS2- and κ-casein, coded by the loci CSN1S1, CSN2, CSN1S2 and CSN3 respectively. In other goat breeds, the casei…
Genetic characterization of the Mascaruna goat, a Sicilian autochthonous population, using molecular markers
2013
The aim of this work was to characterize a Sicilian autochthonous goat population using microsatellite markers and genetic polymorphisms at the casein genes. In order to investigate the genetic structure of the Mascaruna goat, a total of 60 (20 Girgentana, 20 mixed populations, and 20 Mascaruna) individuals were analyzed, using a panel of 18 microsatellite markers. Moreover, the Mascaruna goats were genotyped at casein loci using several molecular techniques. Based on the genetic structure at casein genes, the Mascaruna goat was similar to most goat breeds from the Mediterranean area, which are characterized by the predominance of strong alleles. The low value of genetic differentiation amo…
Relazione tra SNPs ai loci caseinici e tipizzazione lattoproteica nella capra Girgentana
2006
La filogenesi della razza Girgentana ancora oggi rimane più o meno sconosciuta sebbene l’ipotesi più valida sembrerebbe quella che la ricollega alla capra Falconeri o Markor (Himalaya). La consistenza numerica della razza nell’ultimi anni ha subito una notevole contrazione, tanto da potersi annoverare tra le razze in via di estinzione. Il latte della capra Girgentana era utilizzato solo per il consumo diretto. Quando è entrato in vigore il regolamento che vietava la vendita del latte al dettaglio, il valore zoo-economico della razza Girgentana è diminuito notevolmente, contribuendo alla contrazione numerica della razza nell’ultimo ventennio. La rivalutazione della razza sarebbe di fondament…
Indagine preliminare sul polimorfismo lattoproteico in diverse popolazioni caprine allevate in Sicilia.
2004
La consistenza del patrimonio caprino in Italia ha subito negliiltimi anni un aumento considerevole. Significativo è stato l’incremento del 6,6% della produzione di latte tra il 2000 e il 2002. Il recente sviluppo dell’allevamento caprino è dovuto in gran parte al crescente interesse dei consumatoru sia verso i prodotti caseari tipici sia verso il consumo diretto del latte. Le caseina caprine sono caratterizzate da un elevato polimorfismo genetico, sia a livello qualitativo che quantitativo, diventato oggetto di un generale interesse scientifico per le importanti relazioni con la qualità e le caratteristiche nutrizionali e tecnologiche del latte. Il patrimonio caprino siciliano è rappresent…
Influenza del genotipo per l'alfa s1 caseina sulla qualità del latte di capre Maltesi
2010
INTRODUZIONE I numerosi studi sui polimorfismi lattoproteici della capra hanno evidenziato per il gene che codifica per l’alfa (s1)-caseina (CSN1S1) 17 alleli: A, B1, B2, B3, B4, C, D, E, F, G, O1, O2, H, I, L, M, N. Tali alleli sono stati associati a differenti tassi di sintesi di caseina e classificati in quattro gruppi quantitativi: alleli forti (A, B1, B2, B3, B4, C, H, L, M) intermedi (E ed I) e deboli (D, F e G) che sintetizzano rispettivamente un alto (circa 3,5 g/l), medio (circa 1,1 g/l), e basso (0,45 g/l) quantitativo di alfa (s1)-caseina, più alleli nulli (01, 02 e N) che non sintetizzano alfa (s1)-caseina (1, 2). Le varianti genetiche per l’alfa (s1)-caseina influenzano in misu…