Search results for " changes"
showing 10 items of 824 documents
Les climats régionaux : observation et modélisation : actes du colloque
2012
6 pages; International audience; L'objectif de cette étude est de caractériser les variations spatio-temporelles des flux sédimentaires de la basse vallée du Mono-Couffo (bassin versant partagé par le Bénin et le Togo), à partir des données de matières en suspension (MES), de débits solides (TSS), de pluie, du débit et des données concernant l'occupation du sol pour mieux apprécier l'impact de la dégradation du couvert végétal sur le flux des sédiments terrigènes. Il ressort de l'analyse une diminution de plus de 60 % des formations naturelles entre les années 1956 et 2000, contribuant à une augmentation des apports spécifiques dans la basse vallée. Une charge solide considérable en matière…
Burial dissolution of micrite in Middle East carbonate reservoirs (Jurassic–Cretaceous): keys for recognition and timing.
2006
14 pages; International audience; This paper discusses burial diagenesis and especially a burial dissolution phase and its effects on micrite microtexture in reservoirs in the Middle East. Three microporous reservoirs were selected: the Cenomanian Mishrif Formation in Iraq; the Kimmeridgian–Tithonian Arab D and the Barremian Kharaib Formations, both in Abu Dhabi. Staining, cathodoluminescence and scanning electron microscopy were used for petrographic observations. In the selected reservoirs, three typical micrite microtextures are distinguished: micro-rhombic, compact anhedral, and rounded. The chronology of diagenesis, based on petrographic observations, shows that mineralogical stabilisa…
Single-Cell Analysis of RNA Virus Infection Identifies Multiple Genetically Diverse Viral Genomes within Single Infectious Units
2015
Summary Genetic diversity enables a virus to colonize novel hosts, evade immunity, and evolve drug resistance. However, viral diversity is typically assessed at the population level. Given the existence of cell-to-cell variation, it is critical to understand viral genetic structure at the single-cell level. By combining single-cell isolation with ultra-deep sequencing, we characterized the genetic structure and diversity of a RNA virus shortly after single-cell bottlenecks. Full-length sequences from 881 viral plaques derived from 90 individual cells reveal that sequence variants pre-existing in different viral genomes can be co-transmitted within the same infectious unit to individual cell…
Epigenetic changes and nuclear factor-κB activation, but not microRNA-224, downregulate Raf-1 kinase inhibitor protein in triple-negative breast canc…
2015
Raf-1 kinase inhibitor protein (RKIP) is a tumor suppressor and metastasis inhibitor, which enhances drug-induced apoptosis of cancer cells. Downregulation of RKIP may be significant in the biology of highly aggressive and drug-resistant tumors, for example triple-negative breast cancers (TNBCs). Potential causes for the low levels of RKIP expressed by SUM 159 TNBC cells were investigated in the present study. Bisulphite modification, methylation specific-polymerase chain reaction (PCR) and a TransAM NF-κB assay were performed and the results suggested that various mechanisms, including methylation of the gene promoter, histone deacetylation and nuclear factor-κB (NF-κB) activation, but not…
Childhood cancer:Survival, treatment modalities, late effects and improvements over time
2021
Since the 1960s, paediatric oncologists have gradually become better organised in large study groups and participation in clinical trials is today considered as the standard of care, with most children with cancer in Europe and North America being enrolled on available treatment protocols. Chemotherapy is nowadays the main element of therapy, but irradiation is still required for some patients. With the advent of multimodality therapy and supportive care, five-year cancer survival exceeds 80 % in most European and North American countries today. The substantial improvements in survival led to a constantly growing population of childhood cancer survivors. Concerns regarding the risk of late …
Time-related changes in size of nuclei of pinealocytes in rats
1981
In a study of 96 adult male Sprague-Dawley rats, da- and time-related changes of the mean nuclear volume of pinealocytes were determined with the aim of testing the reproducibility of the karyometric findings described by Quay and Renzoni (1966). It is shown (i) that statistically significant differences exist between the central and peripheral mean volumes of pinealocyte nuclei/group of animals and time point (p less than 0.001), (ii) that the day and time related differences are statistically different in both regions (p less than 0.001), (iii) that in the center and periphery of the pineal body different diurnal patterns exist, and (iv) that the diurnal patterns are not parallel in the t…
Erosion en milieu sableux cultivé au Niger : dynamique actuelle et passée en liaison avec la pression anthropique et les changements climatiques
2011
Sahelian ecosystems, especially those installed on sandy soils react very quickly and intensely to small climatic changes. In this semi-arid area, wind erosion which occurs mainly on cultivated millet fields and is threatening the sustainable use of land resources. Furthermore, the rapid population growth and the severe droughts of the twentieth century have had important impacts on ecosystems. To better manage this fragile environment, it is important first to understand how it works. This thesis was included in the framework of the AMMA project (African Monsoon Multidisciplinary Analyses) and was in the heart of a CORUS 2 (Coopération pour la Recherche Universitaire et Scientifique) progr…
Les hêtraies du Châtillonnais (Côte-d'Or) face au changement climatique.
2013
15 pages; International audience; L'étude traite des hêtraies du Châtillonnais (Côte-d'Or, Bourgogne) face au changement climatique observé. Les données regroupent les séries bourguignonnes de température et de précipitation des stations de Météo France (1989-2009), la carte des hêtraies de l'Institut forestier national (IFN), un modèle numérique de terrain (MNT, SRTM) et quatre indices de vulnérabilité du hêtre identifiés dans la littérature. La méthode repose sur une interpolation fine (mailles de 100 m) de ces indices par régression-krigeage. Les résultats permettent de cartographier les risques actuels.
Vulnérabilité des forêts de douglas du Morvan face au changement climatique : l'expérience de 2003
2010
International audience; Contexte et problématique : Lors de l'été 2003, les forêts bourguignonnes ont subi une sécheresse et une canicule dont l'intensité n'avait jamais été observée. Ce double stress hydrique et thermique a provoqué d'importants dépérissements, en particulier chez le douglas. Compte tenu de l'importance économique de cette essence en Bourgogne et de l'évolution climatique probable, il est nécessaire de suivre la vitalité des peuplements et de comprendre les facteurs de variations de la vulnérabilité des peuplements de douglas face à un type d'aléa dont la fréquence sera très probablement accrue dans les décennies à venir. Données et méthode : Pour cela sont analysées : - l…
Speciation of Al3+ in fairly concentrated solutions (20 to 200 mmol L-1) at I = 1 mol L-1 (NaNO3), in the acidic pH range, at different temperatures.
2011
AbstractThe hydrolysis of Al3+ was studied in aqueous 1 mol L−1 NaNO3 solution at different concentrations (20–200 mmol L−1) and temperatures (283.15–343.15 K) by potentiometry (ISE-H+, glass electrode). Many different speciation models were considered in the calculations and it was found that the best model is represented by the following species: Al(OH)2+, Al(OH)45+, Al13(OH)327+. Hydrolysis constants and enthalpy changes at different temperatures are reported.