Search results for " cohort study"

showing 10 items of 3126 documents

A retrospective study of the prevalence and characteristics of dens invaginatus in a sample of the Turkish population.

2012

Objective: The purpose of this study was to assess the prevalence of dens invaginatus and to classify the types of dens invaginatus in a sample of the Turkish population.. Study Design: A retrospective study was performed using periapical and panoramic radiographs of 5355 patients who presented to the Department of Oral Diagnosis and Radiology at the Ondokuz Mayıs University Dentistry Faculty between January 2009 and December 2010. Maxillary and mandibular anterior teeth were evaluated for the presence and characteristics of dens invaginatus. Statistical evaluation of the presence of dens invaginatus related to gender was performed by the Pearson chi-squared test. Results: Dens invaginatus …

AdultMaleTurkish populationAdolescentTurkeyvirusesTurkishLarge populationDentistryOdontologíadigestive systemcomplex mixturesDens invaginatusYoung Adultfluids and secretionsmedicinePrevalenceHumansDens invaginatusOral Diagnosisdens in denteGeneral DentistryAnterior teethAgedRetrospective StudiesPeriodontitisOral Medicine and Pathologybusiness.industryRetrospective cohort studydental anomalyMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]Ciencias de la saluddigestive system diseasesPeriapical lesionDens in DenteOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASSurgeryFemaleResearch-ArticlebusinessMedicina oral, patologia oral y cirugia bucal
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Neoplasms of the salivary glands in a Turkish adult population

2009

WOS: 000284036700011

AdultMaleTurkish populationPathologymedicine.medical_specialtyAdolescentTurkeyAdenoid cystic carcinomaTurkishTurkishneoplasmsBenign tumorPleomorphic adenomaYoung AdultHumansMedicineNeoplasmGeneral DentistryAgedRetrospective StudiesSalivary glandSalivary glandbusiness.industryRetrospective cohort studyMiddle AgedSalivary Gland Neoplasms:CIENCIAS MÉDICAS [UNESCO]medicine.diseaselanguage.human_languagemedicine.anatomical_structureOtorhinolaryngologyUNESCO::CIENCIAS MÉDICASlanguageFemaleSurgerybusiness
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The frequency and characteristics of idiopathic osteosclerosis and condensing osteitis lesions in a Turkish patient population.

2009

The objective of this study was to investigate the frequency of idiopathic osteosclerosis (IO) and condensing osteitis (CO) in a Turkish patient population, considering factors such as age and sex of the population, in addition to shape and localization, as well as the dental relationship between IO and CO lesions.A retrospective study was performed using panoramic radiographs of 6,154 patients ranging in age from 5 to 69 years old, who had been subjected to dental treatment. Descriptive characteristics of radiopacities, including shape, localization and dental relationship were recorded. The Chi-squared test was used.A total of 238 radiopacities were detected, which included 185 IO lesions…

AdultMaleTurkish populationmedicine.medical_specialtyAdolescentTurkeyRadiographyCondensing osteitisDentistryIdiopathic osteosclerosisYoung AdultRadiography PanoramicMedicineHumansPulpitisYoung adultChildGeneral DentistryOsteitisAgedRetrospective Studiesbusiness.industryRetrospective cohort studyMiddle Agedmedicine.disease:CIENCIAS MÉDICAS [UNESCO]SurgeryPatient populationOtorhinolaryngologyChild PreschoolUNESCO::CIENCIAS MÉDICASSurgeryFemalebusinessOsteosclerosisMedicina oral, patologia oral y cirugia bucal
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Statement of severe trauma management in France; teachings of the FIRST study

2013

Abstract Introduction The blunt trauma victim management is still a matter of debate and comparing studies involving different emergency medical services and health care organization remains fictitious. Hence, the French Intensive care Recorded in Severe Trauma (FIRST) was conducted in order to describe the severe blunt trauma management in France. The present paper aimed at recalling the main results of FIRST study. Methods The FIRST study was based on a multicenter prospective cohort of patients aged 18 or over with severe exclusive blunt trauma requiring admission to university hospital care unit within the first 72 h and/or managed by medical-Staffed Emergency Mobile Unit (SMUR). Multip…

AdultMaleTypologyAdolescentAircraftCritical CareEndpoint DeterminationAmbulancesBlood PressureWounds NonpenetratingYoung AdultPatient AdmissionIntensive careHealth careEmergency medical servicesmedicineHumansGlasgow Coma ScaleProspective cohort studyAgedAged 80 and overbusiness.industryData CollectionAge FactorsBasic life supportGeneral MedicineMiddle Agedmedicine.diseasePatient Care ManagementAnesthesiology and Pain MedicineSevere traumaBlunt traumaAccidentsWounds and InjuriesFemaleFranceMedical emergencyTriageTomography X-Ray ComputedbusinessAnnales Françaises d'Anesthésie et de Réanimation
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Prognostic Relevance of Cardiorespiratory Fitness as Assessed by Submaximal Exercise Testing for All-Cause Mortality: A UK Biobank Prospective Study

2020

Objective: To investigate if the inverse associations of cardiorespiratory fitness (CRF) with all-cause and cardiovascular mortality in the general population vary among individuals who are at different pre-test risk. Patients and Methods: CRF was assessed through submaximal bike tests in 58,892 participants aged 40-69 years who completed baseline questionnaires between January 1, 2006 and December 31, 2010 in the UK Biobank study. Participants were categorized into risk categories, which determined allocation to an individualized bike protocol. These were “minimal risk (1)”, “small risk (2)” and “medium risk (3)” groups (i.e., those who cycled at 50%, 35% of predicted maximal workload and …

AdultMaleUK Biobankmedicine.medical_specialtyDatabases FactualPopulationsubmaximal testRisk AssessmentMetabolic equivalentrisk predictionInterquartile rangeCause of DeathInternal medicinemedicineHumansProspective StudiesProspective cohort studyeducationAgedBiological Specimen Bankseducation.field_of_studycardiorespiratory fitnessFramingham Risk Scorebusiness.industryHazard ratioCardiorespiratory fitnessGeneral MedicineMiddle AgedPrognosisUnited KingdomCardiorespiratory FitnessCardiovascular DiseasesExercise Testall-cause mortalityFemaleRisk assessmentbusinessMayo Clinic Proceedings
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EchoScopy in scanning abdominal diseases: initial clinical experience.

2014

Background and Aims: The introduction of a new type of small handheld ultrasound device brings greater portability and affordability. The basic ultrasound approach with these handheld devices has been defined by European Federation of Societies of Ultrasound in Medicine and Biology (EFSUMB) as “EchoScopy”. The current study aimed to assess the image quality, indications and limitations of a portable pocket “EchoScope” compared with a high-end ultrasound system in abdominal diseases. Methods: 231 consecutive patients were included in this study. Physician A performed ultrasound examinations with a high-end ultrasound system (HEUS), then physician B performed the same ultrasound examination u…

AdultMaleUrologic Diseasesmedicine.medical_specialtyAdolescentImage qualityDigestive System DiseasesPilot ProjectsEndocrine System DiseasesSensitivity and SpecificityLesionYoung AdultVascularityAscitesAbdomenMedicineHumansUltrasonography Doppler ColorProspective cohort studyChildPathologicalHydronephrosisAgedAged 80 and overMiniaturizationbusiness.industryUltrasoundGastroenterologyReproducibility of ResultsEquipment DesignMiddle Agedmedicine.diseaseEquipment Failure AnalysisCardiovascular DiseasesFemaleRadiologymedicine.symptombusinessZeitschrift fur Gastroenterologie
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Surveillance for adverse events following immunization (AEFI) for 7 years using a computerised vaccination system

2016

Objectives: The surveillance of vaccine safety is an essential requirement in vaccination programmes. Computerized immunization registries such as the Vaccination Information System (SIV) of Valencian Community (Spain) offer the opportunity to estimate the incidence of adverse events according to individual information. The aim of the study was to analyze adverse events following immunization reported through SIV from 2005 to 2011 by age, sex, type of vaccine and dose, and adverse event, and highlight the advantages of this type of reporting. Study design: A retrospective cohort study of subjects vaccinated in the Valencian Community using population health databases was carried out. Method…

AdultMaleVaccine safetyPediatricsmedicine.medical_specialtyAdolescentDatabases FactualImmunization registryPopulation healthYoung Adult03 medical and health sciences0302 clinical medicine030225 pediatricsProduct Surveillance PostmarketingAdverse Drug Reaction Reporting SystemsHumansMedicine030212 general & internal medicineYoung adultChildAdverse effectAgedRetrospective StudiesVaccinesbusiness.industryIncidence (epidemiology)Public Health Environmental and Occupational HealthInfantRetrospective cohort studyGeneral MedicineMiddle AgedPassive surveillanceVaccinationAEFI (adverse event following immunization)ImmunizationSpainChild PreschoolFemaleSafetybusinessImmunization registry
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Circulating VEGF reduction, response and outcome in advanced colorectal cancer patients treated with cetuximab plus irinotecan

2007

Objective: We designed this trial to investigate if modifications in levels of circulating vascular endothelial growth factor (VEGF) may be related to clinical response and outcome in advanced colorectal cancer patients during treatment with a weekly combination of cetuximab plus irinotecan. Methods: A total of 45 heavily pretreated metastatic colorectal cancer patients were prospectively evaluated for circulating levels of VEGF during the treatment with cetuximab plus weekly irinotecan. VEGF circulating levels were assessed at the following time points: just before and at 1, 21, 50 and 92 days after the start of cetuximab plus irinotecan treatment. Results: Basal VEGF median levels were s…

AdultMaleVascular Endothelial Growth Factor AOncologymedicine.medical_specialtyAngiogenesisColorectal cancerCetuximabAntibodies Monoclonal HumanizedIrinotecanangiogenesiscetuximabcolorectal canceririnotecansurvivalvascular endothelial growth factorBasal (phylogenetics)chemistry.chemical_compoundInternal medicineAntineoplastic Combined Chemotherapy ProtocolsBiomarkers TumorGeneticsmedicineHumansProspective StudiesProspective cohort studyAgedPharmacologyCetuximabbusiness.industryAntibodies MonoclonalMiddle Agedmedicine.diseaseSurvival RateClinical trialVascular endothelial growth factorIrinotecanTreatment OutcomechemistryDisease ProgressionMolecular MedicineCamptothecinFemaleColorectal Neoplasmsbusinessmedicine.drugPharmacogenomics
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Angiogenesis modifications related with cetuximab plus irinotecan as anticancer treatment in advanced colorectal cancer patients

2006

INTRODUCTION Angiogenesis has been correlated with increased invasion and metastases in a variety of human neoplasms. Inadequate inhibition of the growth of tumor microvessels by anticancer agents may result in treatment failure, rated clinically as progressive or stable disease. We designed this trial to investigate the modification of the vascular endothelial growth factor (VEGF) and interferon-gamma (IFN-gamma) in advanced colorectal cancer patients during treatment with a weekly combination of cetuximab plus irinotecan. MATERIALS AND METHODS Forty-five metastatic colorectal cancer patients were prospectively evaluated for circulating levels of VEGF and IFN-gamma during the treatment wit…

AdultMaleVascular Endothelial Growth Factor Amedicine.medical_specialtyAngiogenesisColorectal cancerCetuximabAntibodies Monoclonal HumanizedIrinotecanGastroenterologyNeovascularizationInterferon-gammaBasal (phylogenetics)chemistry.chemical_compoundangiogenesis cetuximab colorectal cancer irinotecanInternal medicineAntineoplastic Combined Chemotherapy ProtocolsmedicineHumansProspective StudiesProspective cohort studyAgedNeovascularization PathologicCetuximabbusiness.industryAntibodies MonoclonalHematologyMiddle Agedmedicine.diseaseVascular endothelial growth factorIrinotecanTreatment OutcomeEndocrinologyOncologychemistryCamptothecinFemalemedicine.symptomColorectal Neoplasmsbusinessmedicine.drug
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Effects of a nutraceutical formulation based on the combination of antioxidants and ω-3 essential fatty acids in the expression of inflamma…

2013

Maria D Pinazo-Durán,1,* Carmen Galbis-Estrada,1,* Sheila Pons-Vázquez,1 Jorge Cantú-Dibildox,2 Carla Marco-Ramírez,1 Javier Benítez-del-Castillo21Ophthalmic Research Unit Santiago Grisolia, Department of Surgery/Ophthalmology, Faculty of Medicine, University of Valencia, Valencia, Spain; 2Department of Ophthalmology, Hospital of Jerez, Jerez de la Frontera, Spain*These authors contributed equally to this workBackground: Women, and those older than 65 years of age, are particularly susceptible to dry eye disorders (DEDs). Inflammation is clearly involved in the pathogenesis of DEDs, and there is mounting evidence on the antioxidant and …

AdultMaleVascular Endothelial Growth Factor Amedicine.medical_specialtyessential polyunsaturated fatty acidsInterleukin-1betaInflammationnutraceuticsGastroenterologyAntioxidantsPathogenesischemistry.chemical_compoundRisk FactorsInternal medicineFatty Acids Omega-3HumansMedicineProspective StudiesInterleukin 6Prospective cohort studyAgedOriginal ResearchAged 80 and overchemistry.chemical_classificationbiologyInterleukin-6business.industryagingtearsInterleukinGeneral MedicineMiddle AgedcytokinesInterleukin-10Vascular endothelial growth factorchemistryClinical Interventions in AgingDietary SupplementsImmunologybiology.proteinTearsDry Eye SyndromesFemalewomenInflammation MediatorsGeriatrics and Gerontologymedicine.symptombusinessPolyunsaturated fatty acidClinical Interventions in Aging
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