Search results for " coi"

Human CD8 T lymphocytes recognize Mycobacterium tuberculosis antigens presented by HLA-E during active tuberculosis and express type 2 cytokines

2015

CD8 T cells contribute to protective immunity against Mycobacterium tuberculosis. In humans, M. tuberculosis reactive CD8 T cells typically recognize peptides associated to classical MHC class Ia molecules, but little information is available on CD8 T cells recognizing M. tuberculosis Ags presented by nonclassical MHC class Ib molecules. We show here that CD8 T cells from tuberculosis (TB) patients recognize HLA-E-binding M. tuberculosis peptides in a CD3/TCR αβ mediated and CD8-dependent manner, and represent an additional type of effector cells playing a role in immune response to M. tuberculosis during active infection. HLA-E-restricted recognition of M. tuberculosis peptides is detectab…

Arginase activity in the blood of patients with visceral leishmaniasis and HIV infection.

2013

Background Visceral leishmaniasis is a parasitic disease associated with high mortality. The most important foci of visceral leishmaniasis in Ethiopia are in the Northwest and are predominantly associated with high rates of HIV co-infection. Co-infection of visceral leishmaniasis patients with HIV results in higher mortality, treatment failure and relapse. We have previously shown that arginase, an enzyme associated with immunosuppression, was increased in patients with visceral leishmaniasis and in HIV seropositive patients; further our results showed that high arginase activity is a marker of disease severity. Here, we tested the hypothesis that increased arginase activities associated wi…

Effectiveness of platinum wire microcoils for venous occlusion: A study on patients treated for venogenic impotence

1994

The purpose of this study was to determine the effectiveness of venous occlusions achieved by embolization with platinum microwire coils. Follow-up venographies in 19 patients, 1-20 months (average 8 months) after coil embolizations, were evaluated. Twenty-eight of 126 (22.2%) coil embolizations were found to be patent. Coils which had not formed or partially formed upon embolization had a patency/recanalization rate of 37.5% (12/32). Among coils which had formed nearly completely or completely only 16 of 95 (17%) showed venous patency. As coil embolization had been augmented by sclerotherapy in all patients, the effectiveness of long-term venous occlusion by platinum wire coils alone is pr…

Transcranial magnetic resonance-guided focused ultrasound surgery at 1.5T: a technical note.

2019

Magnetic resonance-guided focused ultrasound is one of the emerging non-invasive technologies offering both image guidance and thermal monitoring. In recent years transcranial application of this technology is starting to impact heavily the neuroscience field. We present here the imaging protocol and the technological methods successfully used with a transcranial magnetic resonance-guided focused ultrasound system certified for clinical treatments of functional neurological disorders, integrated for the first time with a 1.5T magnetic resonance scanner. Compared to the body radiofrequency coil (the one commonly used with transcranial magnetic resonance-guided focused ultrasound system integ…

Micelle Formation from Amphiphilic“Cylindrical Brush”—Coil Block Copolymers Prepared by Metallocene Catalysis

2004

Application of AC and DC magnetic field for surface wave excitation to enhance mass transfer

2020

Abstract Refining the metallic melts and removal of contaminants from the free surface may be sped up by increasing the surface area of mass exchange interface. It is relevant to both the case of volatile impurity evaporation in a vacuum as well as the case of chemical reactions when the continuous crust of reaction products should be interrupted. Previously proposed low-frequency AC magnetic field excitation of intense surface waves is limited by skin-effect. The induced sign-alternating forcing at high dimensionless frequency values becomes dominantly pulsing at considerably higher than unity values, delivering time-averaged stirring without intense surface waves. Superimposing DC magneti…

Modeling of ITER TF cooling system through 2D thermal analyses and enthalpy balance

2017

Abstract The winding pack of the ITER Toroidal Field (TF) coils is composed of 134 turns of Nb3Sn Cable in Conduit Conductor (CICCs) wound in 7 double pancakes and cooled by supercritical helium (He) at cryogenic temperature. The cooling of the Stainless Steel (SS) case supporting the winding pack is guaranteed by He circulation in 74 parallel channels. A 2D approach to compute the temperature distribution in the ITER TF winding pack is here proposed. The TF is divided in 32 poloidal segments, for each segment the corresponding 2D model is built and a thermal analysis is performed applying the corresponding nuclear heating computed with MCNP code considering the latest design updates, such …

A Magnetostrictive Electric Power Generator for energy harvesting from traffic: Design and experimental verification

2015

In the last decades, the growth in energy demand, the decrease of fossil fuels available in the market and the impact of anthropogenic factors on climate change has given new impulse to research on renewable energy systems, particularly those known as energy harvesting devices (EHDs) [1]. A large number of EHDs have been proposed, using different operating principle [1-4]. Among them, piezoelectric and magnetostrictive seem to be particularly suitable for the application in EHD. In these materials the application of external mechanical stress induces a change in the level of magnetization and therefore an electromotive force (emf) can be generated and collected in order to produce electrica…

1983

The neutron scattering from mixtures of deuterated and undeuterated poly(ethylene oxide), (D-PEO, H-PEO), in the small angle and intermediate angle region has been measured in the melt. We found no indications of a molecular segregation. The value of molecular weight evaluated agreed with that obtained by other methods. For a sample with a molar mass of 120000 g/mol the radius of gyration 〈rw2〉1/2 was found to be 13,6 nm, which corresponds to a characteristic ratio of C = 6,9. The form factor of a single chain can be described by the Debye equation for a random coil with the same unperturbed dimensions. Our results are compared with rotational isomeric state calculations and measurements in…

Development of a Two-Dimensional Simplified Tool for the Analysis of the Cooling of the ITER TF Winding Pack

2018

The cooling of the ITER toroidal field (TF) coils winding pack is guaranteed by the circulation of supercritical helium (He) in seven hydraulic circuits corresponding to the Nb3Sn cable in conduit conductors, and in 74 channels devoted to the cooling of the stainless steel case supporting the winding pack. A tool entirely developed inside ANSYS with the APDL language has been created with the aim of computing the temperature distribution in the TF winding pack in different poloidal locations. The tool also allows the assessment of the He temperature during plasma operation in the case cooling channels. The considered heat load is the volumetric nuclear heating computed with the MCNP code in…