Search results for " contract."
showing 10 items of 1345 documents
Preventive and Therapeutic Role of Muscle Contraction Against Chronic Diseases.
2016
Background: Due to the continuing increase of the elderly population in the western countries, the prevalence of the main chronic diseases (obesity, type 2 diabetes and related metabolic disorders, arterial hypertension, vascular damage due to atherosclerotic process, cancer, chronic obstructive pulmonary disease, neurodegenerative diseases, chronic kidney disease, immune-mediated diseases) is increasing. There is incontrovertible evidence that regular physical activity contributes to the primary and secondary prevention of several chronic diseases and is associated with a reduced risk of premature death. Methods: In this review the most prevalent chronic pathologic conditions are discussed…
Redox modulation of muscle mass and function
2020
Muscle mass and strength are very important for exercise performance. Training-induced musculoskeletal injuries usually require periods of complete immobilization to prevent any muscle contraction of the affected muscle groups. Disuse muscle wasting will likely affect every sport practitioner in his or her lifetime. Even short periods of disuse results in significant declines in muscle size, fiber cross sectional area, and strength. To understand the molecular signaling pathways involved in disuse muscle atrophy is of the utmost importance to develop more effective countermeasures in sport science research. We have divided our review in four different sections. In the first one we discuss t…
Modulation of muscle-tendon interaction in the human triceps surae during an energy dissipation task.
2017
The compliance of elastic elements allows muscles to dissipate energy safely during eccentric contractions. This buffering function is well documented in animal models but our understanding of its mechanism in humans is confined to non-specific tasks, requiring a subsequent acceleration of the body. The present study aimed to examine the behaviour of the human triceps surae muscle-tendon unit (MTU) during a pure energy dissipation task, under two loading conditions. Thirty-nine subjects performed a single-leg landing task, with- and without added mass. Ultrasound measurements were combined with 3D kinematics and kinetics to determine instantaneous length changes of MTUs, muscle fascicles, A…
Hormone replacement therapy improves contractile function and myonuclear organization of single muscle fibres from postmenopausal monozygotic female …
2013
Ageing is associated with a decline in muscle mass and strength leading to increased physical dependency in old age. Postmenopausal women experience a greater decline than men of similar age in parallel with the decrease in female sex steroid hormone production. We recruited six monozygous female twin pairs (55-59 years old) where only one twin pair was on hormone replacement therapy (HRT use = 7.8 ± 4.3 years) to investigate the association of HRT with the cytoplasmic volume supported by individual myonuclei (myonuclear domain (MND) size,) together with specific force at the single fibre level. HRT use was associated with a significantly smaller (∼27%; P < 0.05) mean MND size in muscle fib…
Language teacher identities as socio-politically situated construction: Finnish and Brazilian student teachers’ visualisations of their professional …
2021
Abstract The process of envisioning the future is central to teachers’ identity construction, but different environments create distinct sociocultural conditions for the process. This qualitative study drawing on visual-textual methods compares Finnish and Brazilian student teachers’ desired and feared professional futures. Two different perspectives on future identities were detected: a desire for status and a desire for meaningfulness. The results revealed the radically different social status of teaching in the two countries and the role this played in the envisioned identities. The study highlights the importance of awareness of the socio-political nature of identity construction in dev…
A Smart Contract Based Recommender System
2019
Nowadays information available on the World Wide Web has reached unprecedented growth and it makes difficult for users to find the most relevant for them. In order to alleviate such issue, Recommender Systems (RSs) have been proposed to collect opinions and preferences about a set of items, process such preferences and build a personalized information access. While the most part of current RSs exploit centralized architecture to provide the service, in this manuscript we propose an alternative approach for building a general purpose RSs that provides to users with more transparent and decentralized rating strategy. Indeed, the proposed framework is built on top of a Distributed Ledger techn…
I contratti di rete: valutazioni oltre l'emergenza
2018
The network contract: some evaluations after the emergency. The debate over the Italian network contract develops in the phase of the heaviest crisis for Italians firms. This article evaluates limits and opportunities of network contracts. Findings are based on 14 network cases selected among declining or growing productive sectors in the context of two regions of the South: Apulia and Sicily. Formal networks, although initiated later than in the Northern regions, are indeed now widespread also in the South. The main findings concern the inability of formal networks to support actors to come out of the crisis. Actually, the decline of the sector is one of the most relevant factors that can …
L'efficacité des privatisations françaises : une vision dynamique à travers la théorie de la gouvernance
2004
International audience; A reading of the process of privatization through the corporate governance theory leads to propose a model taking into account, on the one hand, the time dimension of the process of privatization, on the other hand, the contextual, organizational, governance and strategic variables which influence this process. After replicating some traditional tests, we test this model on a sample of French privatized firms and on a seven years horizon. The positive effect traditionally attributed to privatizations is not confirmed. The importance of the effect is subordinated to some of the suggested variables.; Une lecture du processus de privatisation à travers la théorie de la …
Multivariate modeling and analysis of regional ocean freight rates
2018
Abstract In this paper, we propose a new multivariate model for the dynamics of regional ocean freight rates. We show that a cointegrated system of regional spot freight rates can be decomposed into a common non-stationary market factor and stationary regional deviations. The resulting integrated CAR process is new to the literature. By interpreting the common market factor as the global arithmetic average of the regional rates, both the market factor and the regional deviations are observable which simplifies the calibration of the model. Moreover, forward contracts on the market factor can be traded in the Forward Freight Agreement (FFA) market. We calibrate the model to historical spot r…
El killer adquisition theory of harm y la autonomía de las partes: illumina/pacific biosciences y paypal/izettle
2022
: Partiendo del trabajo expuesto por Cunningham, Ederer y Ma titulado: “Killer Acquisition” publicado en el “Journal of Political Economy” en marzo 2021, se analizará la fusión de Illumnia, Inc/Pacific Biosciences of California, Inc (dos empresas del sector biotecnológico) y la de Paypal Holdings/iZettle con el fin de dar respuesta a las siguientes interrogantes: ¿La US Federal Trade Commission contaba con suficiente evidencia jurídica y económica para limitar la autonomía de las partes Illumnia, Inc/Pacific Biosciences of California, en pro de la innovación y competencia o se trató de una coartación a la libertad contractual cuyo único objetivo era la maximización de los rendimientos econó…