Search results for " costs"
showing 10 items of 259 documents
In response: Genomic profile of breast cancer.
2015
Response to: Plun-Favreau J, Svedman C, Valentine W, Rouzier R. Genomic profile of breast cancer. Expert Rev Pharmacoecon Outcomes Res 2015;15(3):393–94We would like to express our gratitude for th...
An Analytic Hierachy Process for Ranking Operating Costs of Low Cost and Full Service Airlines
2009
This paper develops an application of the analytic hierarchy process to rank the operating cost components of full service and low cost airlines. It takes into account the financial balance sheets and answers to a questionnaire submitted to the managers of selected airlines. The results suggest that the analytic hierarchy process can be appropriately used to obtain the ranking of the costs taking into account different views: financial, management and operative. Rental, office equipment and other supplies costs show the highest importance in the cost ranking, both for full services and low cost airlines. The robustness of the results is tested by Monte Carlo analysis.
Selection of the Optimal Design Rainfall Return Period of Urban Drainage Systems
2014
Abstract The aim of this work is to define a methodology to identify the optimal rainfall return period for the design of urban drainage systems. The choice of the optimal return period is made minimizing the total costs of the system: the sewer network is dimensioned for a set of possible design rainfall return periods, and the corresponding construction, maintenance and operation costs are evaluated. For each scenario, the total expected damage from flooding caused by rainfall events with return period greater than the design one is then estimated by hydraulic simulation. This methodology has been applied to a small urban catchment in Palermo (Italy).
Organic farming and economic sustainability: The case of Sicilian durum wheat
2014
In last years, the organic farming in the world is developing rapidly and Italy is the sixth country for organic area. Sicily is the main organic area of Italian territory and represents the first region for organic cereals. Among these durum wheat is the crop most widespread, especially in the hilly hinterland areas. The paper aims to analyze the economic sustainability of organic durum wheat. For this purpose, it has been determined the gross m argin of whea t within crop rotations of the Sici lian hilly hinterland, comparing 10 organic farms with 10 conventional farms. The results show a higher gross margin of organic wheat respect to conventional one, due to lower variable costs and hig…
Limitations of rule 23 on the allocation of costs of teaching and research staff in Spanish public universities
2020
In March 2011, the model of cost accounting for Spanish public universities was approved and published based on the CANOA project of the Ministry of Education, Culture and Sport (MECD 2011). This paper focuses on rule 23 contained in chapter 8 of this document, where which regulates the treatment of the teaching and research dedication of university staff (PDI) and the allocation of corresponding cost to teaching, research and management. A reflection is made on certain points where there is the possibility of making different interpretations or in which satisfactory results are not obtained, with the consequences that this entails in the quality of the information and in the comparisons be…
Public-Private Partnership: Transaction Costs of Tendering
2016
Abstract What are the transaction costs of participating in a public-private partnership (PPP) tender? Prior research indicate that there is a significant amount of resources required. However, few researchers seem to measure transaction costs directly. The purpose of this paper is therefore to fill this knowledge gap by presenting estimated transaction costs from both public and private actors. The underlying approach for this research was a case study of a new primary school in Norway. This case was chosen because of the expedient access to detailed information of the tendering process. The main source of data was documents and estimated figures obtained from public and private actors inv…
Multiobjective shape design in a ventilation system with a preference-driven surrogate-assisted evolutionary algorithm
2019
We formulate and solve a real-world shape design optimization problem of an air intake ventilation system in a tractor cabin by using a preference-based surrogate-assisted evolutionary multiobjective optimization algorithm. We are motivated by practical applicability and focus on two main challenges faced by practitioners in industry: 1) meaningful formulation of the optimization problem reflecting the needs of a decision maker and 2) finding a desirable solution based on a decision maker’s preferences when solving a problem with computationally expensive function evaluations. For the first challenge, we describe the procedure of modelling a component in the air intake ventilation system wi…
Osteoporosis: Economic Burden of Disease in Italy.
2020
Background and Objective: Today, osteoporosis is the most common bone disease and an important public health problem in all developed countries. The objective of this study was to estimate the costs associated with the management and treatment of osteoporosis in order to assess the economic burden in Italy for 2017, in terms of direct medical costs and social security costs. Methods: A cost of illness model was developed to estimate the average cost per year sustained by the NHS (National Health Service) and Social Security System in Italy. A systematic literature review was performed to obtain epidemiological, direct and indirect costs parameters where available. Hospitalisation costs were…
The global burden of chronic urticaria for the patient and society*
2020
Chronic urticaria (CU) affects about 1% of the world population of all ages, mostly young and middle-aged women. It usually lasts for several years (> 1 year in 25-75% of patients) and often takes > 1 year before effective management is implemented. It presents as chronic spontaneous urticaria (CSU), chronic inducible urticaria (CIndU) or both in the same person. More than 25% of cases are resistant to H1 -antihistamines, even at higher doses, and third- and fourth-line therapies (omalizumab and ciclosporin) control the disease only in two-thirds of H1 -antihistamine-resistant patients. Here we review the impact of CU on different aspects of patients' quality of life and the burden of this …
Notional defined contribution pension schemes: Why does only Sweden distribute the survivor dividend?
2015
The aim of this paper is to analyse the role of the survivor dividend in notional defined contribution (NDC) pension schemes. At present, this feature can only be found in the Swedish defined contribution scheme. We develop a model that endorses the idea that the survivor dividend has a strong basis for enabling the NDC scheme to achieve financial equilibrium and that not including the dividend is a non-transparent way of compensating for increases in longevity and/or legacy costs from old pension systems. We also find that the average effect of the dividend remains unchanged for any constant annual rate of population growth, that contribu-tors who reach retirement age always get a higher r…