Search results for " counting"

showing 10 items of 98 documents

Geographical mapping of metabolites in biological tissue with quantitative bioluminescence and single photon imaging

1993

This article features a novel technique for measuring the spatial distribution of metabolites, such as ATP, glucose, and lactate, in rapidly frozen tissue. Concentration values are obtained in absolute terms and with a spatial resolution of single-cell dimension. The method is based on enzymatic reactions that link the metabolite of interest to luciferase with subsequent light emission. Using a specific array, cryosections are brought into contact with the enzymes in a well-defined, reproducible way inducing a distribution of light across the section with an intensity that is proportional to the metabolite concentration. The emitted light can be visualized through a microscope and an imagin…

Cell SurvivalMetaboliteUterine Cervical NeoplasmsCarbohydrate metabolismBiologyMiceStructure-Activity Relationshipchemistry.chemical_compoundAdenosine TriphosphateNeoplasmsTumor Cells CulturedAnimalsFrozen SectionsHumansBioluminescenceTissue DistributionLuciferaseLactic AcidMelanomaCells Culturedchemistry.chemical_classificationMice Inbred BALB CStaining and LabelingHistocytochemistryMyocardiumCell BiologyPhoton countingRatsLactic acidGlucoseEnzymechemistryBiochemistryLuminescent MeasurementsLactatesBiophysicsFemaleLight emissionAnatomyThe Histochemical Journal
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The effect of temperature on the internal dynamics of dansylated POPAM dendrimers

2011

The internal and rotational dynamics of the dansylated poly(propylene amine) dendrimers (POPAM) have been studied by time correlated single photon counting (TCSPC) and molecular dynamics (MD) simulations. The hydrodynamic volumes of the dendrimer generations from G1 to G4 were estimated by fluorescence anisotropy data. Experiments and simulations suggest that the volume and the shape of the dendrimers are temperature dependent. At low temperatures the dendrimer structure becomes more spacious and rigid and back-folding of the individual branches is slowed down. For the G3 and G4 generations the temperature effects are much stronger than for the smaller G1 and G2 generations, where back-fold…

ChemistryGeneral Chemical EngineeringDynamics (mechanics)NanotechnologyGeneral ChemistryPhoton countingSolventMolecular dynamicsChemical physicsDendrimerSurface modificationDENDRIMERSRotational dynamicsta116Fluorescence anisotropyRSC Advances
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Application of fast solvent extraction processes to studies of exotic nuclides

1998

Fast solvent extraction is a chemical separation method, which can be applied to study exotic nuclides. Since about 1970 the SISAK technique, which is an on-line method based on multi-stage solvent extraction separations, has been successfully used to investigate the nuclear properties of β-decaying nuclides with half-lives down to about one second. During the last decade it has become possible to produce transactinide elements in high enough yields to investigate their chemical properties on a one-atom-at-a-time scale. For this purpose it was necessary to improve and change the detection part of the SISAK system in order to be capable to detect spontaneously fissioning and α-decaying nucli…

ChemistryHealth Toxicology and MutagenesisNuclear engineeringLiquid scintillation countingPublic Health Environmental and Occupational HealthAnalytical chemistryTransactinide elementChemical separation methodPollutionAnalytical ChemistryNuclear Energy and EngineeringRadiology Nuclear Medicine and imagingNuclideSolvent extractionSpectroscopyJournal of Radioanalytical and Nuclear Chemistry
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Investigations of Chl a aggregates cross-linked by dioxane in 3-methylpentane

1997

In this work, dioxane-bound aggregates of chlorophyll a are prepared in 3-methylpentane. The properties of the aggregates are studied by using steady-state and time-resolved spectroscopies. The Q -region absorption spectrum of the y chlorophyll a-dioxane aggregate shows four clearly resolvable narrow bands with comparable intensities. The band maxima are located at 683, 689, 698 and 702 nm. The emission spectrum consists of two emission bands centred at 699 and 702 nm suggesting the presence of two types of aggregates. High degree of fluorescence polarization is detected yielding the angles between the absorption transition moments with respect to the 702 nm emission transition moment. The …

Circular dichroismSingle-photon countingAbsorption spectroscopyChlorophyll aTransition dipole momentBiophysicsAnalytical chemistry010402 general chemistry01 natural sciencesBiochemistryMolecular physicsDioxane aggregate03 medical and health sciencesFluorescence polarizationEmission spectrumAbsorption (electromagnetic radiation)030304 developmental biology0303 health sciencesChemistryCell Biology0104 chemical sciencesψ-type circular dichroismWavelengthExcitation delocalizationExcitationFluorescence anisotropyBiochimica et Biophysica Acta (BBA) - Bioenergetics
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Aufbau und Arbeitsweise eines 12-Kanal- funktionsmeβstandes zur Erfassung und Auswertung schnell ablaufender hämodynamischer Vorgänge

1970

Hemodynamic function studies with radioactive tracers A new set-up, a multichannel function test device, is described for performing hemodynamic function studies with radioactive tracers. After injection of radioactive labelled particles of definite physical and chemical properties, the distribution of radioactivity can be registered simultaneously as function of time at 6 different sites of the body. Each of the 6 detectors used, one of them can be replaced by a fore-arm counter, is equipped with two channels, which can be individually adjusted to the photopeaks of two different radioisotopes. The data are either/not only stored on magnetic tape or/but also fed into a memory unit operating…

Continuous registrationWhole body countingRadiationChemistryRoutine workDetectorAnalytical chemistryMagnetic tapeFunction (mathematics)Time savinglaw.inventionExponential functionNuclear Energy and EngineeringlawRadiology Nuclear Medicine and imagingBiological systemThe International Journal of Applied Radiation and Isotopes
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Analyzing big datasets of genomic sequences: fast and scalable collection of k-mer statistics

2019

Abstract Background Distributed approaches based on the MapReduce programming paradigm have started to be proposed in the Bioinformatics domain, due to the large amount of data produced by the next-generation sequencing techniques. However, the use of MapReduce and related Big Data technologies and frameworks (e.g., Apache Hadoop and Spark) does not necessarily produce satisfactory results, in terms of both efficiency and effectiveness. We discuss how the development of distributed and Big Data management technologies has affected the analysis of large datasets of biological sequences. Moreover, we show how the choice of different parameter configurations and the careful engineering of the …

Data AnalysisFOS: Computer and information sciencesTime FactorsTime FactorComputer scienceStatistics as TopicBig dataApache Spark; distributed computing; performance evaluation; k-mer countinglcsh:Computer applications to medicine. Medical informaticsBiochemistryDomain (software engineering)Databases03 medical and health sciences0302 clinical medicineStructural BiologyComputer clusterStatisticsSpark (mathematics)Molecular Biologylcsh:QH301-705.5030304 developmental biology0303 health sciencesGenomeSettore INF/01 - InformaticaBase SequenceNucleic AcidApache Sparkbusiness.industryResearchApache Spark; Distributed computing; k-mer counting; Performance evaluation; Algorithms; Base Sequence; Software; Time Factors; Data Analysis; Databases Nucleic Acid; Genome; Statistics as TopicApplied Mathematicsk-mer countingDistributed computingComputer Science ApplicationsAlgorithmData AnalysiComputer Science - Distributed Parallel and Cluster Computinglcsh:Biology (General)030220 oncology & carcinogenesisScalabilityPerformance evaluationlcsh:R858-859.7Algorithm designDistributed Parallel and Cluster Computing (cs.DC)Databases Nucleic AcidbusinessAlgorithmsSoftware
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X-X through-cage bonding in Cu, Ni, and Cr complexes with M3X2 cores (X=S, As).

2008

Density functional calculations on trinuclear complexes bridged by two sulfur atoms, [(tmeda)(3)Cu(3)(mu-S)(2)](3+), [(tmeda)(3)Ni(3)(mu-S)(2)](2+), and [(tmeda)(3)Ni(3)(mu-S(2))](4+), as well as on the formation of [(tmeda)(3)Cu(3)(mu-S)(2)](3+) from a dinuclear [(tmeda)(2)Cu(2)(mu-S(2))](2+) complex and a mononuclear [(tmeda)Cu(eta(2)-S(2))](+) fragment, are reported. A qualitative orbital analysis of the M(3)X(2) framework bonding is presented for the case in which each metal atom M has a square planar coordination sphere completed by one bidentate or two monodentate ligands (that is, [(L(2)M)(3)X(2)] compounds). It is concluded that a framework electron count (FEC) of 12 corresponds to …

DenticityCoordination sphereChemistryStereochemistryOrganic Chemistrychemistry.chemical_elementGeneral ChemistryCopperCatalysisMetalCrystallographyvisual_artAtomvisual_art.visual_art_mediumMolecular orbitalCageElectron countingChemistry (Weinheim an der Bergstrasse, Germany)
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128-Channel Silicon Strip Detector Installed at a Powder Diffractometer

2004

Silicon strip detectors represent a new class of one-dimensional position-sensitive single photon counting devices. They allow a reduction of measurement time at the powder diffractometers by a factor up to 100 compared to instruments with a single counter, while maintaining comparable count statistics. Present work describes a 128-channel detector working with a standard diffractometer. The detector is 12.8 mm long and covers the angular range of 3.2 deg. We discuss the diffraction geometry in real and reciprocal space, the FWHM of diffraction peaks, and the background level. Measurements were made on standard samples and on complex samples of industrial importance (e. g., portland clinker…

DiffractionMaterials scienceSiliconbusiness.industryMechanical EngineeringDetectorchemistry.chemical_elementCondensed Matter PhysicsPhoton countingReciprocal latticeOpticschemistryMechanics of MaterialsPowder DiffractometerGeneral Materials SciencebusinessPowder diffractionDiffractometerMaterials Science Forum
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Point counting on Picard curves in large characteristic

2005

We present an algorithm for computing the cardinality of the Jacobian of a random Picard curve over a finite field. If the underlying field is a prime field Fp, the algorithm has complexity O(p).

Discrete mathematicsAlgebra and Number TheoryApplied MathematicsJacobian varietyGeometryField (mathematics)Computational Mathematicssymbols.namesakeMathematics::Algebraic GeometryFinite fieldPoint countingCardinalityJacobian matrix and determinantsymbolsPicard hornPrime fieldMathematicsMathematics of Computation
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Dimensions of random affine code tree fractals

2014

We calculate the almost sure Hausdorff dimension for a general class of random affine planar code tree fractals. The set of probability measures describing the randomness includes natural measures in random $V$-variable and homogeneous Markov constructions.

Discrete mathematicsCode (set theory)v-variable fractalsApplied MathematicsGeneral MathematicsProbability (math.PR)ta111Dynamical Systems (math.DS)self-similar setsTree (descriptive set theory)Box countingFractalIterated function systemMathematics - Classical Analysis and ODEsHausdorff dimensionClassical Analysis and ODEs (math.CA)FOS: MathematicsAffine transformationMathematics - Dynamical Systems28A80 60D05 37H99RandomnessMathematics - ProbabilityMathematics
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