Search results for " culturali"
showing 10 items of 1669 documents
EPR/ALANINE PELLETS WITH LOW Gd CONTENT FOR NEUTRON DOSIMETRY
2013
This paper reports on results obtained by electron paramagnetic resonance (EPR) measurements and Monte Carlo (MC) simulation on a blend of alanine added with low content of gadolinium oxide (5 % by weight) to improve the sensitivity to thermal neutron without excessively affecting tissue equivalence. The sensitivity is enhanced by this doping procedure of more an order of magnitude. The results are compared with those obtained with the addition of boric acid (50 % by weight) where boron is in its natural isotopic composition in order to produce low-cost EPR dosemeters. The gadolinium addition influences neutron sensitivity more than the boron addition. The presence of additives does not sub…
Neutron flux and gamma dose measurement in the BNCT irradiation facility at the TRIGA reactor of the University of Pavia
2018
Abstract University of Pavia is equipped with a TRIGA Mark II research nuclear reactor, operating at a maximum steady state power of 250 kW. It has been used for many years to support Boron Neutron Capture Therapy (BNCT) research. An irradiation facility was constructed inside the thermal column of the reactor to produce a sufficient thermal neutron flux with low epithermal and fast neutron components, and low gamma dose. In this irradiation position, the liver of two patients affected by hepatic metastases from colon carcinoma were irradiated after borated drug administration. The facility is currently used for cell cultures and small animal irradiation. Measurements campaigns have been ca…
Study of the response of phenol compounds exposed to thermal neutrons beams for Electron Paramagnetic Resonance dosimetry
2015
Abstract This paper reports the results regarding a new organic compound (IRGANOX ® 1076 phenols) with and without low content (5% by weight) of gadolinium oxide (Gd 2 O 3 ) for Electron Paramagnetic Resonance (EPR) dosimetry of neutron beams. The dependence of EPR signal as function of neutron dose was investigated in the fluence range studied between 10 11 cm −2 to 10 14 cm −2 . We evaluated also the effect of gadolinium on 60 Co gamma photon sensitivity of this organic compound. Our analysis showed that a low concentration of gadolinium oxide (of the order of 5% of the total mass of the dosimeter) can enhance the thermal neutron sensitivity more than 10 times with a small reduction of …
Hydration dependence of myoglobin dynamics studied with elastic neutron scattering, differential scanning calorimetry and broadband dielectric spectr…
2014
In this work we present a thorough investigation of the hydration dependence of myoglobin dynamics. The study is performed on D2O-hydrated protein powders in the hydration range 0<h<0.5 (h≡gr[D2O]/gr[protein]) and in the temperature range 20-300K. The protein equilibrium fluctuations are investigated with Elastic Neutron Scattering using the spectrometer IN13 at ILL (Grenoble), while the relaxations of the protein + hydration water system are investigated with Broadband Dielectric Spectroscopy; finally, Differential Scanning Calorimetry is used to obtain a thermodynamic description of the system. The effect of increasing hydration is to speed up the relaxations of the myoglobin + hydration …
Biodistribution of Insulin-Nanogels in Mouse: A Preliminary Study for the Treatment of Alzheimer's Disease
2017
A growing body of evidence shows that Insulin, Insulin Receptor (IR) and IR signaling are involved in brain cognitive functions and their dysfunction is implicated in Alzheimer's disease (AD) neurodegeneration. Thus, administration of insulin could be a strategy for AD treatment. For this aim we have designed, synthesized and characterized a nanogel system (NG) that has been conjugated to insulin molecules (NG-In) to deliver the protein into the brain, as a tool for the development of a new therapy against AD. In our preclinical study in mice, intraperitoneal injection of fluorescent-labeled NG has allowed to determine the biodistribution of NG vs time in the whole body and its clearance th…
VITTIME, ATTORI E LUOGHI DELLA DISCRIMINAZIONE
2011
il contributo mette in evidenza come la marginalità economica, la discriminazione culturale e l'esclusione civile intersecandosi tra loro colpiscano singoli individui e gruppi svantaggiandoli ulteriormente.
12C ion beam dose distribution in presence of medium inhomogeneities: comparison between different measurements and simulations with the treatment pl…
2012
Heavy-ions beams offer several advantages compared to other radiation such as low lateral scattering and high biological effectiveness (RBE) in the Bragg peak region, making them particularly attractive for the treatment of radio-resistant tumours localized close to organs at risk [1]. The extension of ion therapy to new clinical cases requires the exploitation of a dedicated treatment planning system (TPS) based on the existing version of TRiP98 [2,3], established TPS for carbon ions. The theoretical models and experimental databases included in TRiP98 are presently mainly based on measurements in water. This approximation can be applied successfully to reproduce many biological tissues wi…
Il ruolo dei media informativi nelle emergenze: dal cortocircuito al sostegno
2012
Il saggio analizza il processo di gestione delle informazioni nei casi eccezionali, come i disastri naturali, che stravolgono le routines produttive dei media.
Islamic Art in the Mediterannean. Italy. Siculo-Norman Art. Islamic culture in medieval Sicily. Art Books International
2004
Il volume inserisce la Sicilia in un Ciclo di Mostre internazionali voluto dall’Organizzazione Non Governativa Museo Senza Frontiere (con sede a Bruxelles) e realizzato come progetto di partenariato euromediterraneo MEDA con la collaborazione del Museo d’Arti Orientali di Stoccolma, il Museo d’Arti Orientali di Roma, il Museo Archeologico di Madrid e i Ministeri della cultura della Spagna, dell’Egitto, della Tunisia e della Giordania. Le “mostre” MSF assumono come “spazio museale” i territori locali, e organizzano percorsi di lettura tematica del patrimonio culturale radicato al territorio, al fine di coinvolgere questo in un circuito virtuoso di valorizzazione e di scambi culturali. Ogni m…
Le strade degli "itinerari". Ragionamenti intorno alla promozione del territorio e dei beni culturali attraverso l'offerta di itinerari tematici
2010
Valutazioni sulle relazioni positive tra beni culturali e turismo e riflessioni sulla metodologia di costruzione di percorsi di visita guidati per la conoscenza dei beni culturali nel loro contesto urbano o rurale. Gli itinerari come prodotti e beni culturali.