Search results for " cyst"

Hypoxia Positively Regulates the Expression of pH-Sensing G-Protein–Coupled Receptor OGR1 (GPR68)

2016

Background & Aims: A novel family of proton-sensing G-proteinâcoupled receptors, including ovarian cancer G-proteinâcoupled receptor 1 (OGR1) (GPR68) has been identified to play a role in pH homeostasis. Hypoxia is known to change tissue pH as a result of anaerobic glucose metabolism through the stabilization of hypoxia-inducible factor-1α. We investigated how hypoxia regulates the expression of OGR1 in the intestinal mucosa and associated cells. Methods: OGR1 expression in murine tumors, human colonic tissue, and myeloid cells was determined by quantitative reverse-transcription polymerase chain reaction. The influence of hypoxia on OGR1 expression was studied in monocytes/macrophages and…

Hsp60 in embryonic and adult submandibular salivary gland: quantitative distribution patterns in normal tissue and comparison with benign and maligna…

2019

Introduction: Heat Shock Protein 60 (Hsp60) is a member of the chaperoning system that assists protein folding inside mitochondria and plays other roles beyond these organelles. It is implicated in the carcinogenic processes in various types of cancer. In human salivary glands, Hsp60 has not yet been measured or mapped in detail and its role in gland development and functioning is virtually unknown. Consequently, its potential as biomarker for gland diseases, including malignancies cannot be assessed. The S-100 protein, a known marker for schwannomas, has been found also in myoepithelial-cell carcinomas of the salivary glands. Here, we present our initial findings on the anatomic-histologic…

Aneurysmal bone cyst of the mandible : case presentation and review of the literature

2007

The aneurysmatic osseus cyst is a very infrequent bone lesion which in some occasions can be found at the craneofacial skeleton. Among all the cystic lesions that can be found at the mandible or the maxilla it is very rare. On the other side it is at the same time very interesting in terms of its differential diagnose with other types of maxillary bone lesions We present the case of a Caucasian male with an aneurysmatic cyst located at the right angle of the mandible and a review of the literature concerning the case. We have focused on the differential diagnose, mainly with the malignancies that can be found at this location. We also comment the therapeutic options clasically described for…

Apoptosis and cell cycle aberrations in epithelial odontogenic lesions : an evidence by the expression of p53, Bcl-2 and Bax

2017

Background Ameloblastoma (AMB), odontogenic keratocyst (OKC) and adenomatoid odontogenic tumor (AOT) are epithelial odontogenic lesions with diverse biologic profiles. Defects in regulation of apoptosis and cell cycle may be involved in the development and progression of those lesions, therefore we aimed to investigate the expression of Bcl-2, Bax and p53 to better understand the possible role of these proteins in AMBs, OKCs and AOTs. Material and Methods The studied sample consisted of 20 AMBs, 20 OKCs and 20 AOTs. Immunohistochemistry technique was performed for the antibodies p53, Bcl-2 and Bax. Immunoreactivity was observed in the epithelial component and positive cells were counted in …

The community of Cystoseira brachycarpa J. Agardh emend. Giaccone (Fucales, Phaeophyceae) in a shallow hydrothermal vent area of the Aeolian Islands …

2014

A Cystoseira brachycarpa community from a vent area off Panarea Island (Italy) was investigated in two sites at different pH values. At low pH, species richness and coverage were low and the community displayed a reduced reproductive capacity. Conversely, at normal pH, dense canopies of fertile C. brachycarpa were found.

Impact of stage migration on bladder cancer: A slow but steady improvement in the long term survival rates after radical cystectomy in the last 25 ye…

2016

INTRODUCTION & OBJECTIVES: Bladder cancer (BCa) is a heterogeneous disease with up to 25% of incidental diagnoses reported to be found muscle invasive at first episode. Numerous markers and an increased awareness have been recorded in the recent years. We sought to evaluate if those considerat ions may determine a change in BCa clinical presentation at radical cystectomy (RC) over years in a single high volume tert iary referral center. MATERIAL & METHODS: The study relied on 2,003 consecutive BCa pat ients treated with RC and extended pelvic lymphadenectomy (PLND) at a single inst itution between January 1990 and December 2014. Pat ients were st ratified into tertiles according to …

IMPACT OF THE SITE OF RECURRENCE AFTER RADICAL CYSTECTOMY ON SURVIVAL: DIFFERENT SITES FOR DIFFERENT OUTCOMES

2015

VARIANT HISTOLOGIC DIFFERENTIATION IN BLADDER CANCER TREATED WITH RADICAL CYSTECTOMY: INCIDENCE AND LONG TERM SURVIVAL IN A SINGLE INSTITUTION STUDY.

2016

Botryoid odontogenic cyst : clinical and pathological analysis in relation to recurrence

2007

Objetives. Botryoid odontogenic cyst (BOC) is considered as an unusual multilocular variant of lateral periodontal cyst (LPC). Review of the literature indicates that this lesion has higher risk of recurrence than LPC, but objetive reasons are still unknown. The aim of this study is identify main clinical and pathological variables associated with the risk of recurrence. Study design. A complete literature review about cases of BOC was made, from its first description up to the year 2006. A total of 67 cases of BOC were identified from year 1973 (first case) to the last publication in 2005. Results. 85.2% of the BOCs were located in the jaw, affecting to women (54.8% of the cases) in the fi…

Integrated stratigraphy of the Oxfordian global stratotype section and point (GSSP) candidate in the Subalpine Basin (SE France).

2014

44 pages; International audience; An integrated biostratigraphic approach, based on ammonites, calcareous nannofossils, dinoflagellates, combined with sedimentology, carbon-isotope and physical stratigraphy, is proposed for the Subalpine Basin (Thuoux and Saint-Pierre d'Argençon sections). Within the expanded marl deposits of the Terres Noires Fm., the Callovian-Oxfordian boundary is particularly well defined by ammonite taxa from different families (i.e. Cardioceratidae, Oppeliidae, Aspidoceratidae and Perisphinctidae), calcareous nannoplankton (first occurrence of large-sized Stephanolithion bigotii) and dinoflagellate cysts (first occurrence of Wanaea fimbriata). This precise biostratigr…