Search results for " dam"
showing 4 items of 1404 documents
Neuronal effects of Sugammadex in combination with Rocuronium or Vecuronium.
2017
Rocuronium (ROC) and Vecuronium (VEC) are the most currently used steroidal non-depolarizing neuromuscular blocking (MNB) agents. Sugammadex (SUG) rapidly reverses steroidal NMB agents after anaesthesia. The present study was conducted in order to evaluate neuronal effects of SUG alone and in combination with both ROC and VEC. Using MTT, CASP-3 activity and Western-blot we determined the toxicity of SUG, ROC or VEC in neurons in primary culture. SUG induces apoptosis/necrosis in neurons in primary culture and increases cytochrome C (CytC), apoptosis-inducing factor (AIF), Smac/Diablo and Caspase 3 (CASP-3) protein expression. Our results also demonstrated that both ROC and VEC prevent these…
Passive Control of Linear Structures Equipped with non-Linear Viscous Dampers and Amplification Mechanism
2008
Fluid damper devices in civil structures such as buildings or bridges are commonly used as energy absorbers for seismic protection. The problem in the response analysis of structures with filled dampers mainly consists in the fact that, due to the strongly nonlinear behavior of such equipments, the response spectrum technique fails. Moreover, in order to enhance the damping effect various toggle brace configurations have been recently proposed. In this paper by using the concept of power spectral density function compatible with the elastic response spectrum and the stochastic linearization technique, the equivalent damping ratio is obtained. It is shown that once the system is linearized r…
Stochastic seismic analysis of MDOF structures with viscous damper devices
2009
Fluid damper devices in civil structures such as buildings or bridges are commonly used as energy absorbers for seismic protection. The problem in the response analysis of structures with filled dampers mainly consists in the fact that, due to the strongly nonlinear behavior of such equipments, the response spectrum technique fails. In this paper by using the concept of power spectral density function compatible with the elastic response spectrum and the stochastic linearization technique, the equivalent damping ratio is obtained. It is shown that once the system is linearized results obtained by Monte Carlo simulation and those obtained by stochastic analysis are in good agreement. Respons…