Search results for " day"
showing 10 items of 182 documents
BIOM-08. DNA METHYLATION-BASED SUBGROUPING PREDICTS SURVIVAL BENEFIT FROM LOMUSTINE/TEMOZOLOMID COMBINATION THERAPY IN MGMT PROMOTOR-METHYLATED GLIOB…
2021
Abstract BACKGROUND The CeTeG/NOA-09 trial showed that lomustine/temozolomide chemotherapy prolongs survival for newly diagnosed MGMT-methylated glioblastoma patients. Previous reports on temozolomide monotherapy suggested, that the survival benefit of temozolomide in MGMT-methylated tumors may be restricted to the RTK II methylation subgroup and absent in RTK I and MES subgroups. To identify patients with a particularly strong benefit from CCNU/TMZ, we explored the association of methylation subgroups with outcome after lomustine/temozolomide therapy. METHODS All patients from the CeTeG/NOA-09 trial with sufficiently available tumor tissue (n = 98) underwent 850K methylation array analysis…
Classroom Management and Loss of Time at the Lesson Start: A Preliminary Study
2013
<p style="text-align:justify">Lesson starts are transitional events which may cause management problems for teachers. In this study 131 lesson starts of equally many teachers were observed in primary and secondary schools in Finland. The results indicated that, in general, the problems were minimal. However, for various reasons lesson starts were delayed by an average of about six minutes. Calculated on this basis, the total loss of instructional time in the whole school year was about five weeks of schooling. No statistically significant relationships were observed between disturbances in the classroom and any background variable studied including grade level, classroom type,(special…
Millstone coastal quarries of the Mediterranean: A new class of sea level indicator
2014
The coasts of Italy still preserve several remnants of coastal quarries built in antiquity, that now provide insights into the intervening sea-level changes occurred during the last millennia. In this paper, we show and discuss a new class of sea level indicator consisting of millstones carved along the rocky coast of southern Italy since 2500 BP, that are currently submerged. They were extracted from beachrocks, sandstones or similar sedimentary rocks, easier for carving by ancient carving tools. Our study focuses on 10 coastal sites located at Capo d'Orlando, Avola, and Letojanni, in Sicily; Soverato, Tropea, and Capo dell'Armi, in Calabria; Castellabate, Palinuro, and Scario, in Campania…
Day-to-day routines of media platform use in the digital age: A structuration perspective
2020
Using Giddens's structuration theory, this study examines how the routinized use of traditional and new media platforms differently align with the structures of everyday life. We analyzed data from a quantitative diary study in Germany to find that new media platforms specifically affect societal structuration by blurring the lines between obligations and leisure time. The part played by routines in the use of new media platforms was less strongly connected to clock time compared to traditional media platforms. Consequently, the findings indicate both a vanishing potential for media platform use as a social zeitgeber and the relevance of rules as structuring elements.
Seasonal and daily variation in physical activity among three-year-old Finnish preschool children
2013
The purposes of this study were to assess seasonal, daily, and gender variations in children’s physical activity (PA). ActiGraph GT3X accelerometers were used to record the three-year-old children’s PA levels for five consecutive days in autumn and winter. Complete data for both seasons were obtained for 47 children. Despite a significant difference in seasonal temperatures (p < .001), differences were only found for weekdays light PA (p = .021). No difference in PA was observed between weekdays and weekend days. Only 20% of the sample had ≥120 minutes light-to-vigorous PA (LMVPA), and 46% of children had ≥60 minutes moderate-to-vigorous PA (MVPA). Boys spent more minutes in LMVPA (p = .001…
Medico-legal implications of sleep apnoea syndrome: driving license regulations in Europe.
2008
Background: Sleep apnoea syndrome (SAS), one of the main medical causes of excessive daytime sleepiness, has been shown to be a risk factor for traffic accidents. Treating SAS results in a normalized rate of traffic accidents. As part of the COST Action B-26, we looked at driving license regulations, and especially at its medical aspects in the European region. Methods: We obtained data from Transport Authorities in 25 countries (Austria, AT; Belgium, BE; Czech Republic, CZ; Denmark, DK; Estonia, EE; Finland, FI; France, FR; Germany, DE; Greece, GR; Hungary, HU; Ireland, IE; Italy, IT; Lithuania, LT; Luxembourg, LU; Malta, MT; Netherlands, NL; Norway, EC; Poland, PL; Portugal, PT; Slovakia,…
KOSMOS 2018 Gran Canaria mesocosm study: water column biogeochemistry
2021
The data set compiles biogeochemical water column collected during a KOSMOS mesocosm experiment carried out in the frame work of the Ocean Artificial Upwelling project. The experiment was performed in the North-East Atlantic Ocean off the coast of Gran Canaria in autumn 2018 and lasted for 39 days. In this study we investigated the effect of different intensities of artificial upwelling combined with two upwelling modes (recurring additions versus one singular addition) on POC export and its potential transfer efficiency to depth. The data set includes the amounts of surface water that were exchanged with nutrient-rich deep water (from ~300 m depth), primary production and chlorophyll a, el…
KOSMOS 2018 Gran Canaria mesocosm study: particle flux data from sediment trap
2021
The data set compiles sinking flux data collected during a KOSMOS mesocosm experiment carried out in the frame work of the Ocean Artificial Upwelling project. The experiment was performed in the North-East Atlantic Ocean off the coast of Gran Canaria in autumn 2018 and lasted for 39 days. In this study we investigated the effect of different intensities of artificial upwelling combined with two upwelling modes (recurring additions versus one singular addition) on POC export and its potential transfer efficiency to depth. The data set includes the amounts of surface water that were exchanged with nutrient-rich deep water (from ~300 m depth). It also contains particle flux data, i.e. POC flux…
Change in weight and central obesity by positive airway pressure treatment in obstructive sleep apnea patients: longitudinal data from the ESADA coho…
2018
The effect of positive airway pressure treatment on weight and markers of central obesity in patients with obstructive sleep apnea remains unclear. We studied the change in body weight and anthropometric measures following positive airway pressure treatment in a large clinical cohort. Patients with obstructive sleep apnea with positive airway pressure treatment from the European Sleep Apnea Database registry (n = 1, 415, 77% male, age 54 ± 11 [mean ± SD] years, body mass index 31.7 ± 6.4 kg/m2, apnea–hypopnea index 37 ± 24 n per hr, Epworth Sleepiness Scale 10.2 ± 5.0) were selected. Changes in body mass index and neck/waist/hip circumferences at baseline and at follow-up visit were analyse…
Nationwide evaluation of day-to-day clinical pharmacists' interventions in German hospitals.
2015
tudy Objective To describe and evaluate the extent and diversity of nationwide data from clinical pharmacists’ interventions (PIs) in German hospitals. Design Retrospective analysis. Data Source The ADKA-DokuPIK German database, a national anonymous self-reported Internet-based documentation system for routine PIs as well as for medication errors reported by German hospital pharmacists. Measurements and Main Results Data sets from ADKA-DokuPIK entered between January 2009 and December 2012 were analyzed descriptively. A total of 27,610 PIs were entered, mainly by ward-based clinical pharmacists (82.5%). Most of the PIs were performed on surgical wards (37.8%), followed by anesthesiology/int…