Search results for " density"

showing 10 items of 2709 documents

Serum interleukin-6 in patients with metastatic bone disease: correlation with cystatin C.

2008

The clinical significance of serum interleukin-6 (IL-6) and its correlation with cystatin C (Cyst C), an endogenous inhibitor of cysteine proteinase cathepsin K, was investigated by immunoassays in patients with bone metastasis from breast cancer (BCa) or prostate cancer (PCa). Additional studies were also performed in these patients to assess the effects of zoledronic acid (ZA) administration on the circulating levels of these molecules. Mean IL-6 and Cyst C serum concentrations were signifi- cantly increased in BCa patients and in patients with primary osteoporosis (PU) compared to healthy subjects (HS). However, Cyst C, but not IL-6, resulted significantly more elevated in BCa patients t…

MaleCancer Researchmedicine.medical_specialtyPathologyBone diseasemedicine.medical_treatmentBone NeoplasmsBreast NeoplasmsZoledronic AcidGastroenterologyProstate cancercancer metastatic bone disease cystatin cInternal medicineBiomarkers TumormedicineHumansCystCystatin CAgedAged 80 and overBone Density Conservation AgentsDiphosphonatesbiologyInterleukin-6business.industryImidazolesProstatic NeoplasmsCancerBone metastasisHematologyGeneral MedicineMiddle AgedProstate-Specific AntigenBisphosphonatemedicine.diseaseZoledronic acidROC CurveOncologyCystatin Cbiology.proteinOsteoporosisFemalebusinessmedicine.drug
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THE INTENSITY OF SEXUAL SELECTION PREDICTS WEAPON SIZE IN MALE BOVIDS

2007

As a classical example of a sexually selected trait, the horns of male bovids offer a prime opportunity to identify predictors of the intensity of sexual selection. Here I use the comparative method to quantify sexual and natural selection pressures behind interspecific variation in horn length. I show that male horn length depends on factors proposed to affect the mean mate number per mating male, correlating positively with group size and negatively with male territoriality. This suggests that whereas group size increases the opportunity for sexual selection, territoriality reduces it because territorial males are unable to follow and monopolize female groups as effectively as males in no…

MaleCompetitive BehaviorTerritorialityBiologyGeneticsAnimalsSelection GeneticPhylogenyEcology Evolution Behavior and SystematicsSelection (genetic algorithm)HornsPopulation DensitySex CharacteristicsNatural selectionHorn (anatomy)EcologyTemperatureRuminantsMating Preference AnimalMating systemBiological EvolutionSexual dimorphismSexual selectionFemaleTerritorialityGeneral Agricultural and Biological SciencesBody Temperature RegulationDemographySex characteristicsEvolution
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Costs of coexistence along a gradient of competitor densities: an experiment with arvicoline rodents

2006

Summary 1 Costs of coexistence for species with indirect resource competition usually increase monotonically with competitor numbers. Very little is known though about the shape of the cost function for species with direct interference competition. 2 Here we report the results of an experiment with two vole species in artificial coexistence in large enclosures, where density of the dominant competitor species (Microtus agrestis) was manipulated. Experimental populations of the subordinate vole species (Clethrionomys glareolus) were composed of same aged individuals to study distribution of costs of coexistence with a dominant species within an age-cohort. 3 Survival and space use decreased …

MaleCompetitive Behaviormedia_common.quotation_subjectField volePopulationCompetition (biology)Seasonal breederAnimalseducationMicrotusEcosystemEcology Evolution Behavior and Systematicsmedia_commonPopulation Densityeducation.field_of_studybiologyArvicolinaeEcologyFeeding BehaviorInterspecific competitionbiology.organism_classificationBank voleFemaleAnimal Science and ZoologyVoleSeasonsJournal of Animal Ecology
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Predation as a landscape effect: the trading off by prey species between predation risks and protection benefits.

2007

1. Predators impose costs on their prey but may also provide benefits such as protection against other (e.g. nest) predators. The optimal breeding location in relation to the distance from a nesting raptor varies so as to minimize the sum of costs of adult and nest predation. We provide a conceptual model to account for variation in the relative predation risks and derive qualitative predictions for how different prey species should respond to the distance from goshawk Accipiter gentilis nests. 2. We test the model predictions using a comprehensive collection of data from northern Finland and central Norway. First, we carried out a series of experiments with artificial bird nests to test if…

MaleCost-Benefit AnalysisOvipositionForagingPopulation DynamicsRisk AssessmentPredationNesting BehaviorBirdsSongbirdsNestSpecies SpecificityAbundance (ecology)AnimalsNest boxEcology Evolution Behavior and SystematicsPopulation DensitybiologyRaptorsEcologyReproductionAccipiterBird nestbiology.organism_classificationHabitatPredatory BehaviorAnimal Science and ZoologyFemaleThe Journal of animal ecology
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Gray value measurement for the evaluation of local alveolar bone density around impacted maxillary canine teeth using cone beam computed tomography

2021

Background To investigate whether any relationship between local alveolar bone density and maxillary canine impaction using gray values from cone beam computed tomography. Material and Methods The cone beam computed tomography images of 151 patients were retrospectively evaluated. Maxillary canine was defined as an impacted tooth when root formation was complete and the patient’s age older than 13 or the other side of the maxillary canine has completely erupted. Similarly, complete eruption was defined as the tooth in its expected occlusion and position. Using the cone beam computed tomography software, the region of interest which was 5 mm2 in area, was placed in the trabecular bone on cro…

MaleCuspidCone beam computed tomographyBone densitydiagnosisBone DensityOcclusionMaxillaHumansMedicineGeneral DentistryUNESCO:CIENCIAS MÉDICASDental alveolusRetrospective StudiesOrthodonticsOral Medicine and Pathologybusiness.industryImpactionImpacted toothResearchTooth ImpactedMaxillary canineIncreased Bone DensityCone-Beam Computed Tomographynonodontogenic cystsOtorhinolaryngologyFemaleoral cavitySurgeryoral pathologybusinessMedicina Oral Patología Oral y Cirugia Bucal
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Up to a quarter of patients with osteonecrosis of the jaw associated with antiresorptive agents remain undiagnosed

2014

AbstractRecent data suggest that the traditional definition of bisphosphonate-associated osteonecrosis of the jaw (ONJ) may exclude patients who present with the non-exposed variant of the condition. To test the hypothesis that a proportion of patients with ONJ remain undiagnosed because their symptoms do not conform to the traditional case definition, we did a secondary analysis of data from MISSION (Multicentre study on phenotype, definition and classification of osteonecrosis of the jaws associated with bisphosphonates), a cross-sectional study of a large population of patients with bisphosphonate-associated ONJ who were recruited in 13 European centres. Patients with exposed and non-exp…

MaleDelayed DiagnosisSettore MED/50 - Scienze Tecniche Mediche ApplicateAntineoplastic AgentsOsteonecrosis; Jawbones; BisphosphonatesOsteonecrosis; Jawbones;BisphosphonatesSettore MED/29 - Chirurgia MaxillofaccialeSettore MED/28 - Malattie OdontostomatologicheOsteonecrosis; Jawbones; Bisphosphonates;JawbonesBisphosphonateHumansDiagnostic Errorsosteonecrosis; jawbones; bisphosphonatesPeriodontal DiseasesAgedPain MeasurementBone Density Conservation AgentsOsteonecrosisBisphosphonatesMiddle AgedCross-Sectional StudiesPhenotypeOtorhinolaryngologyTooth DiseasesTooth ExtractionOsteonecrosiOsteoporosisSurgeryBisphosphonate-Associated Osteonecrosis of the JawFemaleOral SurgeryJawbone
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Hampered long-term depression and thin spine loss in the nucleus accumbens of ethanol-dependent rats.

2014

Alcoholism involves long-term cognitive deficits, including memory impairment, resulting in substantial cost to society. Neuronal refinement and stabilization are hypothesized to confer resilience to poor decision making and addictive-like behaviors, such as excessive ethanol drinking and dependence. Accordingly, structural abnormalities are likely to contribute to synaptic dysfunctions that occur from suddenly ceasing the use of alcohol after chronic ingestion. Here we show that ethanol-dependent rats display a loss of dendritic spines in medium spiny neurons of the nucleus accumbens (Nacc) shell, accompanied by a reduction of tyrosine hydroxylase immunostaining and postsynaptic density 95…

MaleDendritic spineDendritic SpinesGlutamic AcidNucleus accumbensNeurotransmissionMedium spiny neuronSynaptic TransmissionNucleus AccumbensOrgan Culture TechniquesAnimalsRats WistarLong-term depressionLong-Term Synaptic Depressiondopamine synaptic plasticity Golgi glutamateMultidisciplinaryNeuronal PlasticityEthanolDopaminergic NeuronsLong-Term Synaptic DepressionCentral Nervous System DepressantsRatsAlcoholismPNAS PlusSynaptic plasticitySettore BIO/14 - FarmacologiaPsychologyNeurosciencePostsynaptic densityProceedings of the National Academy of Sciences of the United States of America
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Impact of a multimodal exercise program on tibial bone health in adolescents with Development Coordination Disorder : an examination of feasibility a…

2020

Objectives: Developmental coordination disorder (DCD) compromises bone health purportedly due to lower levels of physical activity. The potential of an exercise intervention to improve bone health parameters in adolescents with DCD has not previously been studied. This study thus aimed to determine the impact of a multimodal exercise intervention on bone health in this population at-risk of secondary osteoporosis. Methods: Twenty-eight adolescents (17 male, 11 female) aged between 12-17 years (Mage=14.1) with DCD participated in a twice weekly, 13-week generalised multimodal exercise intervention. Peripheral quantitative computed tomography scans of the tibia (4% and 66%) were performed ove…

MaleDevelopmental DisorderAdolescentluuphysical activityluuntiheysDevelopmental Coordination DisordernuoretBone DensityHumansbone healthChildExercisedyspraksiadevelopmental disorderTibiaexercisekuntoliikuntaliikuntarajoitteetPhysical ActivityBone HealthExercise TherapyMotor Skills DisordersPhysical FitnessFeasibility StudiesOriginal ArticleFemalefyysinen aktiivisuusliikuntahoitofysiologiset vaikutukset
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International Olympic Committee (IOC) Consensus Statement on Relative Energy Deficiency in Sport (RED-S): 2018 Update

2018

In 2014, the International Olympic Committee (IOC) published a consensus statement entitled “Beyond the Female Athlete Triad: Relative Energy Deficiency in Sport (RED-S)”. The syndrome of RED-S refers to: “impaired physiological functioning caused by relative energy deficiency, and includes but is not limited to impairments of metabolic rate, menstrual function, bone health, immunity, protein synthesis, and cardiovascular health.”

MaleFemale athlete triadmedicine.medical_specialtyConsensusStatement (logic)Sports scienceMedicine (miscellaneous)030209 endocrinology & metabolismlow testosteroneBone healthamenorrheaFeeding and Eating Disorders03 medical and health sciences0302 clinical medicineMetabolic Diseasesfemale athlete triadlow bone mineral densitymedicineHumansDisabled PersonsOrthopedics and Sports MedicineDisordered eatingPsychiatryNutrition and Dieteticsbusiness.industryMalnutrition030229 sport sciencesGeneral Medicinedisordered eatingmedicine.diseaselow energy availabilitySports Nutritional Physiological Phenomenarelative energy deficiency in sport (RED-S)AthletesMetabolic rateFemaleAmenorrheamedicine.symptomEnergy IntakeEnergy MetabolismbusinessSportsRelative energyInternational Journal of Sport Nutrition and Exercise Metabolism
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The association of calcium intake with osteoporotic vertebral fractures in a large Chinese cohort

2019

The effect of calcium on prevention of osteoporosis and related fracture which are aging issues is unclear. The aim of this study is to explore the association of calcium intake with vertebral fracture. This study enrolled 3,457 participants from China Action on Spine and Hip Status (CASH) study from 2013 and 2017. Dietary calcium intake was collected using validated food frequency questionnaires (FFQ). Vertebral fracture of CT images was defined as the primary outcome. The mean calcium intake of men and women were 522.75mg/day and 507.21mg/day, respectively. 6% reduction in the odds of fracture risk was observed per 100 unit increase of calcium intake from food among females (OR, 0.94; 95%…

MaleFracture riskcalcium intake vertebral fracture QCTChinaAgingmedicine.medical_specialtyPopulationOsteoporosischemistry.chemical_elementCalciumCohort StudiesPrimary outcomeAsian PeopleBone DensityRisk FactorsInternal medicinecalcium intakemedicineHumansProspective StudieseducationDietary calciumvertebral fractureAgedSex Characteristicseducation.field_of_studyBone Density Conservation AgentsFood frequencybusiness.industryCell BiologyMiddle Agedmedicine.diseaseCalcium DietarychemistryCohortOsteoporosisSpinal FracturesCalciumFemalebusinessQCTOsteoporotic FracturesResearch Paper
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