Search results for " density"
showing 10 items of 2709 documents
Bone density of the calcaneus and fractures in 75- and 80-year-old men and women
1994
Bone mineral density of the calcaneus in relation to fractures was studied both retrospectively and prospectively among the 75- and 80-year-old men and women resident in the city of Jyväskylä, Finland, in 1989 and 1990, respectively. The bone measurements were performed at the calcaneus by 125I-photon absorption. Retrospective fracture (RF) history after age 50 was collected by questionnaire and interview, and reported fractures were checked from medical records. In the retrospective study, in the 75-year-olds a fracture was found in 22% (n = 22) of men and in 45% (n = 84) of women. The corresponding figures for the 80-year-olds were 16% (n = 9) and 35% (n = 48). Over half of the fractures …
Serum osteocalcin in relation to calcaneal bone mineral density in elderly men and women: a 5-year follow-up
2000
A 5-year follow-up study investigated serum concentrations of total (tOC) and intact (iOC) osteocalcin in relation to calcaneal bone mineral density (BMD). The study comprised two cohorts, 75- and 80-year-olds, both resident in the city of Jyvaskyla, Finland. Baseline OC and BMD were obtained for 161 men and 233 women, of whom 83 men and 189 women participated in follow-up bone measurements. The mean concentration of tOC increased from 9.6 +/- 4.3 to 13.2 +/- 8.5 microg/l (P = 0.001) in men and from 11.2 +/- 4.9 to 14.0 +/- 6.1 microg/l (P < 0.001) in women, whereas mean iOC decreased from 6.4 +/- 3.0 to 5.9 +/- 3.0 microg/l (P = 0.273) and from 7.7 +/- 3.7 to 6.9 +/- 3.4 microg/l (P = 0.02…
The use of zoledronic acid in patients with bone metastases from prostate carcinoma: Effect on analgesic response and bone metabolism biomarkers
2005
Zoledronic acid is a bisphosphonate that is effective in the treatment of complications of metastatic bone disease. We have carried out a perspective study on 24 consecutive patients with prostate cancer metastatic to bone to verify the effect of zoledronic acid on analgesic response and a possible relationship with the levels of bone metabolism biomarkers. Eligibility for this study required prostate cancer patients with metastatic bone disease and pain not controlled by analgesics. Patients were excluded from the study if they were receiving cytotoxic chemotherapy or radiation therapy within three months. Eighteen patients (75%) were considered responder to acid zoledronic, only 6 patient…
Evaluation of ultrasound transmission velocity and 3-dimensional radiology in different bone types for dental implantology: a comparative ex vivo stu…
2013
Objective To evaluate ultrasound transmission velocity (UTV) for assessment of mechanical bone quality, an ex vivo comparison of different bone types measured with UTV, 2-dimensional (2D) histomorphometry and with 3-dimensional (3D) radiology (cone-beam computerized tomography [CBCT], computerized microtomography [μCT]) was conducted. Study Design Clinical cortical, cancellous, and mixed bone (each n = 6) was measured via UTV (m/s), CBCT (white pixel/black pixel ratio [WP/BP]), μCT (bone volume/total volume [μBV/TV]), and histomorphometry (bone volume/total volume [hBV/TV]). UTV values were correlated with 2D-histomorphometry and 3D-radiologic results. Results For the cortical, cancellous, …
Progress of instability in fragility fractures of the pelvis: An observational study.
2019
Abstract Fragility fractures of the pelvis (FFP) are an increasing entity among elderly persons. Characteristics are different from high-energy pelvic trauma. Little is known about the natural course of FFP in conservative and after operative treatment. Materials and methods Medical charts and radiologic data of 148 patients with an FFP, who were admitted in a 3-year period, were analysed retrospectively. Incidence and characteristics of fracture progression (FP) were noted. Results Patients presenting early after a traumatic event had more often non-displaced fractures, fractures with lower FFP Type classification and were more frequently treated conservatively. FP was observed in 21 cases…
Assessing the risk of osteonecrosis of the jaw due to bisphosphonate therapy in the secondary prevention of osteoporotic fractures
2012
There is evidence that the use oral bisphosphonates can lead to osteronecrosis of the jaws (ONJ). Although the occurrence of ONJ appears rare among oral bisphosphonates (BPs) users, it is important to know that it exists and can be opportunely minimized. INTRODUCTION: The purpose of this study is to evaluate the association between BPs prescribed for the secondary prevention of osteoporotic fractures and the occurrence of ONJ. METHODS: An Italian record linkage claims database with a target population of around 18 million individuals (6 million over 55 years of age) constituted the data source. We conducted a nested case-control study within a cohort of individuals aged 55+ years old, who w…
Functional Evaluation of Emphysema Using Diffusion-Weighted 3Helium-Magnetic Resonance Imaging, High-Resolution Computed Tomography, and Lung Functio…
2004
Purpose: To assess the emphysematous enlargement of distal air-spaces and concomitant large and small airway disease using diffusion-weighted 3 Helium-magnetic resonance imaging (MRI), high-resolution computed tomography (HRCT), and lung function tests (LFT). Methods: Seven patients were examined after single lung transplantation (LTx) and 1 before double LTx for various forms of emphysema. Five patients after double LTx served as controls. Patients were assessed by 3 Helium-MRI (apparent diffusion coefficient [ADC]), HRCT (mean lung density [MLD], emphysema index [El]), and LFT. Results: Transplanted lungs: mean ADC = 0.17 cm 2 /s, MLD = -848 H, El = 22%. Emphysematous lungs: mean ADC = 0.…
A 5-year retrospective longitudinal study on the incidence and the risk factors of osteonecrosis of the jaws in patients treated with zoledronic acid…
2017
Background The aim of this study was to evaluate the incidence and the risk factors of osteonecrosis of the jaw (ONJ) in a group of patients treated with zoledronic acid (ZA) for bone metastases from solid tumors and enrolled in a preventive dental program. Material and Methods This 5-year retrospective longitudinal study included all consecutive oncological patients who underwent at least one infusion with ZA between 2004 and 2011 for bone metastases due to solid neoplasms. Results Of the 156 patients enrolled in the study, 17 developed ONJ (10.89%). At the multivariate analysis, severe periodontal disease (P=0.025), tooth extraction (P<0.0001) and starting the preventive dental program af…
Signal characteristics of EMG during fatigue
1977
Electromyographic (EMG) activity of m. rectus femoris muscle was registered from young male and female subjects during maintained isometric knee extension at 60% of maximal voluntary contraction. The following EMG parameters were analyzed for the entire fatigue time: integrated EMG (IEMG), averaged motor unit potential (AMUP) and power spectral density function (PSDF). The results indicated a slight but continuous rise of IEMG during the fatigue period. AMUP showed sensitivity to fatigue with increase in amplitude, rise time, and number of spikes counted. PSDF was also easily affected by fatigue so that the total power density curve was shifted towards lower frequencies with a high frequenc…
The prevalence of vitamin D deficiency in patients with vertebral fragility fractures
2015
Hypovitaminosis D has been identified as a common risk factor for fragility fractures and poor fracture healing. Epidemiological data on vitamin D deficiency have been gathered in various populations, but the association between vertebral fragility fractures and hypovitaminosis D, especially in males, remains unclear. The purpose of this study was to evaluate serum levels of 25-hydroxyvitamin D (25-OH D) in patients presenting with vertebral fragility fractures and to determine whether patients with a vertebral fracture were at greater risk of hypovitaminosis D than a control population. Furthermore, we studied the seasonal variations in the serum vitamin D levels of tested patients in ord…