Search results for " development"
showing 10 items of 21333 documents
Towards student-centred pedagogy : action research with Ethiopian village school teachers
2018
This study is an action research that was planned and implemented with 23 Ethiopian Village School teachers. The action of the four year project concentrated on developing new, student-centred teaching methods instead of traditional lecturing and rote learning in one remote school. The overall aim of the study was to follow this process and the teachers’ professional development, and to explore how the practical arrangements, such as material or cultural surroundings, constrain or enable usage of student-centred methods at the school. The theoretical framework of the study consists of theories about professional development, action research, and the theory of practice architectures. The dat…
Understanding Language Teacher Identities : Conceptualizations, practices and change
2019
This chapter presents some new approaches and questions in language teacher identity research that could facilitate a better understanding of the work of language teachers, and as a consequence help teacher educators to support them in that work. Language teacher research has shown that periods of change play an important role in identity development. In the field of general teacher research, several studies have addressed the significance of transition phases and changes in curriculum for teacher identities and beliefs. However, there has been some research on the significance of teacher education and transition to full-time teaching for language teacher identity development. A more partic…
Piesardzības principa statuss starptautiskajās vides tiesībās
2017
Piesardzības princips ir koncepts starptautiskajās vides tiesībās, kas ietver ideju, ka zinātniskā neskaidrība nav attaisnojums, lai veiktu darbības, kas kaitīgi ietekmē vidi. Tā statuss kā paražai starptautiskajās tiesībās joprojām tiek uztverts skeptiski, tāpēc darba mērķis ir noskaidrot, vai piesardzības princips ir šādu stausu ieguvis. Šī darba ietvaros tiks aplūkots normatīvais regulējums, tiesu prakse un valstu prakse, lai izpildītu darba uzdevumus- noteikt piesardzības principa definīciju, kā arī noteikt kāds ir opinio juris un valstu prakse attiecībā uz to. Autore uzskata, ka darba rezultātā ir noteicams, ka ir radusies paražu tiesībā attiecībā uz piesardzības principu.
Data from: The oxidative cost of reproduction depends on early development oxidative stress and sex in a bird species
2016
In the early 2000’s, a new component of the cost of reproduction was proposed: oxidative stress. Since then the oxidative cost of reproduction hypothesis has, however, received mixed support. Different arguments have been provided to explain this. Among them, the lack of a life history perspective on most experimental tests was suggested. We manipulated the levels of a key intracellular antioxidant (glutathione) in captive zebra finches (Taeniopygia guttata) during a short period of early life and subsequently tested the oxidative cost of reproduction. Birds were allowed to mate freely in an outdoor aviary during several months. We repeatedly enlarged or reduced their broods to increase or …
DEVELOPMENT & QUALIFICATION OF BIOASSAYS FOR THE DETERMINATION OF THE BIOACTIVITY, PREDICTIVE PHARMACOKINETICS AND POTENTIAL IMMUNOGENICITY OF THERAP…
2021
The critical quality attributes of a given biotherapeutic monoclonal antibody (mAb), its molecular characterization, functional assessment and effector function analysis should be defined and profiled in detail during the life cycle of a biotherapeutic drug. In the past, this product characterization was simple and standardized. In today’s complex world of biologics, success demands a more thoughtful approach and drug developers are investing in advanced analytics much earlier in the development process. Indeed, investing in selected sophisticated and state of the art analytics in early developmental phases of a therapeutic monoclonal antibody may mitigate risks by confirming that the drug …
Biomedyczne aspekty kształtowania płci somatycznej : znaczenie prenatalnego okresu życia
2016
Human sexuality affects many biological, psychological and social aspects. It is connected with gender identity, procreation, experiencing and giving pleasure. From a biological perspective sexual activity is essential for reproduction and its original purpose was to maintain the human species. The article presents the genetic basis of sex determination, differentiation of germ line cells, development of gonads as well as internal and external genital organs, significant for the development of gender identity and propagation. Several factors determining and disrupting proper development of human sex were presented in this article
Norme dal patrimonio culturale per la trasformazione e lo sviluppo sostenibile. Sperimentazione applicata al Piano del Colore delle Isole Egadi
2020
L’arcipelago delle isole Egadi, all'estremità occidentale della Sicilia, custodisce un patrimonio architettonico, paesaggistico e ambientale di grande valore. Dal difficoltoso rapporto tra la popolazione insediata e un ambiente per molti versi ostile, è stato forgiato nei secoli un paesaggio eccezionale, frutto di condizioni estreme di sopravvivenza condizionate dalle esigue risorse locali come la pesca del tonno, l'estrazione della pietra da costruzione e l'agricoltura. L’intero arcipelago è oggi soggetto a vincolo paesaggistico per l’alto valore dei suoi elementi costituenti che si configurano, nella loro interezza, come beni culturali. La texture e le cromie della pietra locale, una calc…
Adrb3 adrenergic receptor is a key regulator of human myometrial apoptosis and inflammation during chorioamnionitis1
2008
The pathophysiology underlying preterm labor triggered by inflammatory conditions such as chorioamnionitis remains largely unclear. It has already been suggested that beta-3 adrenergic (ADRB3) agonists might be of interest in the pharmacological management of preterm labor. Although there is evidence implicating ADRB receptors in the control of inflammation, there are minimal data relating specifically to ADRB3. To explore the cellular consequences of chorioamnionitis and detect apoptosis, we first performed immunostaining and Western blot experiments on human myometrial samples obtained from women with confirmed chorioamnionitis. We then developed an in vitro model of chorioamnionitis by i…
Hard to catch: Experimental evidence supports evasive mimicry
2021
Most research on aposematism has focused on chemically defended prey, but the signalling difficulty of capture remains poorly explored. Similar to classical Batesian and Müllerian mimicry related to distastefulness, such ‘evasive aposematism' may also lead to convergence in warning colours, known as evasive mimicry. A prime candidate group for evasive mimicry areAdelphabutterflies, which are agile insects and show remarkable colour pattern convergence. We tested the ability of naive blue tits to learn to avoid and generalizeAdelphawing patterns associated with the difficulty of capture and compared their response to that of birds that learned to associate the same wing patterns with distast…