Search results for " diabetes"
showing 10 items of 2906 documents
Rationale and design of the DARWIN-T2D (DApagliflozin Real World evIdeNce in Type 2 Diabetes): A multicenter retrospective nationwide Italian study a…
2017
Background Randomized controlled trials (RCTs) in the field of diabetes have limitations inherent to the fact that design, setting, and patient characteristics may be poorly transferrable to clinical practice. Thus, evidence from studies using routinely accumulated clinical data are increasingly valued. Aims We herein describe rationale and design of the DARWIN-T2D (DApagliflozin Real World evIdeNce in Type 2 Diabetes), a multicenter retrospective nationwide study conducted at 50 specialist outpatient clinics in Italy and promoted by the Italian Diabetes Society. Data synthesis The primary objective of the study is to describe the baseline clinical characteristics (particularly HbA1c) of pa…
Eating behavior dimensions and 9-year weight loss maintenance : a sub-study of the Finnish Diabetes prevention study
2023
Abstract Background Behavioral processes through which lifestyle interventions influence risk factors for type 2 diabetes (T2DM), e.g., body weight, are not well-understood. We examined whether changes in psychological dimensions of eating behavior during the first year of lifestyle intervention would mediate the effects of intervention on body weight during a 9-year period. Methods Middle-aged participants (38 men, 60 women) with overweight and impaired glucose tolerance (IGT) were randomized to an intensive, individualized lifestyle intervention group (n = 51) or a control group (n = 47). At baseline and annually thereafter until nine years body weight was measured and the Three Factor Ea…
Tyypin 2 diabeetikoiden ravitsemus- ja liikuntakäyttäytymisen muutosprosessi : hoitajien rohkaisukeinot terveysneuvonnassa
2005
Keskisuomalaisten työikäisten ravitsemustottumusten varhaistunnistaminen ja tyypin 2 diabetesriskin kartoittaminen EVI-hankkeessa mini-intervention j…
2009
Editorial: Emerging Chemical Risks for Human Health: Endocrine Disruption by Per- and Poly-Fluorinated Alkyl Substances (PFAS).
2021
Increased plasma resistin concentrations are associated with atherogenic small, dense low-density lipoproteins in patients with type-2 diabetes
2010
Ruokailutottumukset ja tietoisuus tyypin 2 diabeteksen riskitekijöistä : 5 -vuoden seurantatutkimus aikaisemmin tunnistamattomilla tyypin 2 diabeteks…
2013
Laura Nyrövaara (2013). Ruokailutottumukset ja tietoisuus tyypin 2 diabeteksen riskiteki-jöistä: 5-vuoden seurantatutkimus aikaisemmin tunnistamattomilla tyypin 2 diabetekseen sairastuneilla, heikentyneet sokeriarvot omaavilla ja diabetesta sairastamattomilla. Terveys-tieteiden laitos, Jyväskylän yliopisto, Liikuntalääketieteen pro gradu –tutkielma, 38 sivua, 2 liitettä. Tutkimus on osa Terveyden ja hyvinvoinnin laitoksen FINRISKI 2002 Seurantatutkimusta, jonka tarkoituksena oli selvittää diabeteksen ja muiden glukoosiaineenvaihdunnan häiriöiden esiintyvyys väestössä. Tämän tutkielman tarkoituksena oli selvittää onko ruokailutottumuk-sissa ja tietoisuudessa tyypin 2 diabeteksen riskitekijöi…
Safety of Tyrosine Kinase Inhibitors in Patients With Differentiated Thyroid Cancer: Real-World Use of Lenvatinib and Sorafenib in Korea
2019
Background: Thyroid cancer has become the most common cancer in Korea. Generally, thyroid cancer patients have a good prognosis; however, 15–20% of patients experience recurrence or distant metastasis or are refractory to standard treatment. We assessed the safety of sorafenib and lenvatinib in patients with advanced or metastatic radioactive iodine-refractory differentiated thyroid cancers (DTC) consecutively treated at a tertiary center in South Korea.Methods: We retrospectively reviewed the charts of all consecutive patients with DTC treated during ≥6 months with lenvatinib (February 2016–April 2018) and sorafenib (January 2014–April 2018) at Gangnam Severance Hospital. Patients were tre…
Safety and potential interaction of immunosuppressive drugs for the treatment of inflammatory bowel disease in elderly patients
2021
Inflammatory bowel diseases, including Crohn's disease and ulcerative colitis, are chronic diseases associated with increased morbidity and reduced quality of life. Age may represent a risk factor for adverse events, due to the multimorbidity and polypharmacy, common in elderly patients. Elderly are often not included in clinical trials evaluating efficacy and safety of study drugs for the treatment of inflammatory bowel diseases. Several drugs, such as aminosalicylates, systemic corticosteroids, immunosuppressant drugs, biological drugs and Janus Kinase inhibitors, are available for the management of inflammatory bowel diseases. With the increasing spectrum of therapeutic options, it is th…
Slāpekļa oksīda metabolītu koncentrācija pacientiem ar 1.tipa cukura diabētu
2017
Pamatojums: pētījumos ar 1. tipa diabēta pacientiem tika konstatēta palielināta nitrīta koncentrācija plazmā. Literatūrā nav atrodami dati par nitrīta koncentrāciju 1. tipa diabēta pacientu siekalās. Mērķi: noteikt nitrīta koncentrāciju 1. tipa diabēta pacientu siekalās un tās korelāciju ar slāpekļa oksīda (NO), tā metabolītu nitrātjona (NO3) un nitrītjona (NO2) koncentrāciju asinīs, kā arī blakusslimībām un dzīvesveida faktoriem. Matriāli un metodes: pētījumam tika uzaicināti 44 pacienti no LatDiane kohortas. Dati par diabēta anamnēzi, diētu, fizisko aktivitāti un citiem dzīvesveida faktoriem tika savākti ar anketas palīdzību. 5 ml siekalu tika savākti turpmākai NO2 koncentrācijas analīzei…