Search results for " difference"

showing 10 items of 1369 documents

Intervention study on school meal habits in Norwegian 10-12-year-old children.

2017

Aim: The aim of this study was to investigate whether a free school meal every day was associated with children’s intake of healthy food during school. Methods: A non-randomized study design with an intervention and a control group was used to measure change in children’s meal habits at lunchtime. In total, 164 children participated; 55 in the intervention group and 109 in the control group. Children in the intervention group were served a free, healthy school meal every school day. Participating children completed a questionnaire at baseline and at 6 months’ follow up. Possible associations were evaluated with a healthy food score, which was calculated based on a food frequency questionna…

0301 basic medicineMalemedicine.medical_specialtyFree school mealIntervention groupNorwegian03 medical and health sciencesIntervention (counseling)MedicineHumansChildSchool Health ServicesMeal030109 nutrition & dieteticsbusiness.industryNorwaydigestive oral and skin physiologySignificant differencePublic Health Environmental and Occupational HealthFood ServicesGeneral MedicineFeeding BehaviorSchool mealIntervention studieslanguage.human_languageLunchlanguagePhysical therapyFemaleDiet HealthybusinessFollow-Up StudiesScandinavian journal of public health
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Effect of rinsing time and surface contamination on the bond strength of silorane-based and dimethacrylate-based composites to enamel

2018

Background The aim of this study was to assess whether saliva contamination and rinsing time for 15, 30, and 60 seconds, affects the shear bond strength of silorane and methacrylate-based composites to enamel. Material and Methods Two light cure resin, P60 (3M ESPE) and Filtek LS Silorane were tested. 120 sound premolars were randomly divided into four groups of 30 teeth based on composite type with or without saliva contamination after etching and rinsing. Each group was further divided into three subgroups according to their rinsing time. Then a cylinder of the composite was bonded to the enamel and Shear bond strength was assessed. To determine the failure mode, the bonded surfaces were …

0301 basic medicineMaterials scienceEnamel paintBond strengthResearchComposite number030206 dentistryContaminationMethacrylate:CIENCIAS MÉDICAS [UNESCO]Operative Dentistry and Endodontics03 medical and health sciences030104 developmental biology0302 clinical medicineLeast significant differencestomatognathic systemvisual_artUNESCO::CIENCIAS MÉDICASvisual_art.visual_art_mediumShear strengthAdhesiveComposite materialGeneral Dentistry
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Denosumab for bone health in prostate and breast cancer patients receiving endocrine therapy? A systematic review and a meta-analysis of randomized t…

2019

Highlights • Hormonal receptors positive breast tumor and prostate cancer are managed with endocrine therapies. • Endocrine therapies designed for breast and prostate cancer are often associated to serious adverse skeletal related events, such fractures. • Denosumab is a monoclonal anti-body binding RANKL which acts as inhibitor of osteoclasts activity, thus increasing bone mass. • Denosumab was showed to strongly prevent hormonal therapies-related skeletal issues. • Denosumab administration results safe in bone mass increase and reduction of fractures risk.

0301 basic medicineOncologyRCTs randomized clinical trialrandomized clinical trialslcsh:Diseases of the musculoskeletal systemSettore MED/06 - Oncologia MedicaOsteoporosisBMD bone mass densityReview Articleandrogen deprivation therapyADTlaw.inventionAndrogen deprivation therapyProstate cancerhazard ratio0302 clinical medicineRandomized controlled triallawHRMedicineBreastSAEsCancerProstateRANKLCIMD mean differencelcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogensRCTs randomized clinical trialsDenosumabOncology030220 oncology & carcinogenesisSAEs serious adverse eventsDenosumabmean differencemedicine.drugmedicine.medical_specialtylcsh:RC254-28203 medical and health sciencesBreast cancerRANKL receptor activator of nuclear factor-kB ligandBMDInternal medicineAdverse effectADT androgen deprivation therapyRCTsbusiness.industryMDmedicine.diseaseHR hazard ratioHormonereceptor activator of nuclear factor-kB ligandDiscontinuationCI confidence interval030104 developmental biologyFractureconfidence intervalADT androgen deprivation therapy; BMD bone mass density; Breast; CI confidence interval; Cancer; Denosumab; Fracture; HR hazard ratio; Hormone; MD mean difference; Prostate; RANKL receptor activator of nuclear factor-kB ligand; RCTs randomized clinical trials; SAEs serious adverse eventsserious adverse eventsbone mass densitylcsh:RC925-935businessJournal of Bone Oncology
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Lymphocytes as a Biomarker of Frailty Syndrome: A Scoping Review

2021

Frailty is a geriatric syndrome characterized by a decrease in physiological reserve and reduced resistance to stress, as a result of an accumulation of multiple deficits in physiological systems. Frailty increases the vulnerability to adverse events and is associated with the aging process. Several studies show an association between frailty syndrome and altered blood lymphocyte levels, which is therefore potentially useful for monitoring interventions to improve or delay frailty. The main objective of this review is to provide an analysis of the current evidence related to changes in lymphocyte counts and their associations with frailty syndrome. To that end, the literature published in t…

0301 basic medicineOncologymedicine.medical_specialtyLymphocyteFrailty syndromeReview03 medical and health sciences0302 clinical medicineInternal medicineCD4 cellsMedicineAdverse effectgeriatric evaluationbusiness.industryCD8-cellsRbiomarkersmedicine.diseaseimmunityBlood lymphocyte030104 developmental biologymedicine.anatomical_structuregender differences030220 oncology & carcinogenesisBiomarker (medicine)MedicinebusinessDiseases
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Detection of mast cells in ameloblastomas and odontogenic keratocysts

2020

Background MCs (MCs) have been ascribed to mediating several diseases, including malignant neoplasms. These cells can play a role in angiogenesis, tissue remodeling and immune modulation and favor neoplasm progression. Despite the studies analyzing the contribution of MCs in odontogenic lesions, its biological behavior in ameloblastomas (AMBs) and odontogenic keratocysts (OKCs) remains unclear. This study aims to detect MCs in OKCs and AMBs and clarify the role of MCs in these lesions. Material and methods A total of 40 odontogenic lesions were analyzed. This included 20 OKCs and 20 AMBs, 10 being the solid type and the other 10 being the unicystic type of AMB. All cases were histologically…

0301 basic medicinePathologymedicine.medical_specialtyOral Medicine and Pathology030102 biochemistry & molecular biologybusiness.industryResearchanimal diseasesSignificant differenceImmune modulation:CIENCIAS MÉDICAS [UNESCO]humanitiesOdontogenic03 medical and health sciencesNeoplasm progression0302 clinical medicineTissue remodeling030220 oncology & carcinogenesisUNESCO::CIENCIAS MÉDICASMedicinebusinessGeneral Dentistry
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Distribution of macrophages and plasma cells in apical periodontitis and their relationship with clinical and image data

2017

BACKGROUND Macrophages and plasma cells play a key role in the regulation of innate and adaptive immunity. The aim of this study was to assess the presence of these cells in apical periodontitis and their distribution comparing with clinical and image data. MATERIAL AND METHODS Thirty-three lesions were selected and divided in two groups (17 periapical cysts and 16 periapical granulomas). Immunoreactions using anti-CD68 and anti-CD138 antibodies were carried out; image analysis was performed with an optical microscope and 5 high-power fields from each slide were evaluated leading to an average score of immunoexpression. This mean score was compared between the two groups and correlated with…

0301 basic medicinePathologymedicine.medical_specialtyPeriapical cystPeriapical GranulomaOperative Dentistry and Endodontics03 medical and health sciences0302 clinical medicineMedicineDistribution (pharmacology)General DentistryPeriodontitisbiologybusiness.industryCD68ResearchSignificant difference030206 dentistry:CIENCIAS MÉDICAS [UNESCO]medicine.diseaseAcquired immune system030104 developmental biologyUNESCO::CIENCIAS MÉDICASbiology.proteinAntibodybusinessJournal of Clinical and Experimental Dentistry
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Relationship between adipic acid concentration and the core symptoms of autism spectrum disorders.

2016

Dicarboxylic acids are an important source of information about metabolism and potential physiopathological alterations in children with autism spectrum disorders (ASDs). We measured the concentration between dicarboxylic adipic and suberic acids in children with an ASD and typically-developing (TD) children and analyzed any relationships between the severity of the core symptoms of ASDs and other clinical features (drugs, supplements, drugs, or diet). The core symptoms of autism were evaluated using the DSM-IV criteria, and adipic acid and suberic acid were measured in urine samples. Overall, no increase in the concentration of adipic acid in children with ASDs compared to TD children, how…

0301 basic medicineVitamin bMalePediatricsmedicine.medical_specialtyAdolescentAutism Spectrum DisorderAdipatesUrinebehavioral disciplines and activitiesSeverity of Illness Index03 medical and health scienceschemistry.chemical_compound0302 clinical medicineInternal medicinemental disordersmedicineHumansDicarboxylic AcidsChildBiological PsychiatryAdipic acidbusiness.industrySignificant differenceMetabolismmedicine.diseaseDiagnostic and Statistical Manual of Mental DisordersPsychiatry and Mental health030104 developmental biologyEndocrinologychemistryCase-Control StudiesChild PreschoolDietary SupplementsVitamin B ComplexAutismFemaleCore symptomsCaprylatesbusinessSuberic acid030217 neurology & neurosurgeryPsychiatry research
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Comparison of the root canal debridement ability of two single file systems with a conventional multiple rotary system in long oval-shaped root canal…

2016

Background This study sought to compare the root canal debridement ability of Neolix, Reciproc and ProTaper rotary systems in long oval-shaped root canals. Material and methods Eighty five extracted single-rooted human teeth with long oval-shaped single root canals were selected and divided into three experimental groups(n=25) and one control group (n= 10). Root canals were filled with Vitapex radiopaque contrast medium and prepared with Neolix, Reciproc or ProTaper systems. The control group only received irrigation. Digital radiographs were obtained at baseline and postoperatively and subjected to digital subtraction. The percentage of reduction in contrast medium was quantified at 0-5 mm…

0301 basic medicinebusiness.industryRoot canalmedicine.medical_treatmentResearchSignificant differenceDentistry030206 dentistry:CIENCIAS MÉDICAS [UNESCO]Operative Dentistry and Endodontics03 medical and health sciences030104 developmental biology0302 clinical medicinemedicine.anatomical_structureDebridement (dental)UNESCO::CIENCIAS MÉDICASmedicineIn vitro studybusinessGeneral DentistryMathematics
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Biomarker analysis of the MITO2 phase III trial of first-line treatment in ovarian cancer: Predictive value of DNA-PK and phosphorylated ACC

2016

// Francesco Perrone 1,* , Gustavo Baldassarre 2,* , Stefano Indraccolo 3,* , Simona Signoriello 4 , Gennaro Chiappetta 1 , Franca Esposito 5 , Gabriella Ferrandina 6 , Renato Franco 1,15 , Delia Mezzanzanica 7 , Maura Sonego 2 , Elisabetta Zulato 3 , Gian F. Zannoni 6 , Vincenzo Canzonieri 2 , Giovanni Scambia 6 , Roberto Sorio 2 , Antonella Savarese 8 , Enrico Breda 9 , Paolo Scollo 10 , Antonella Ferro 11 , Stefano Tamberi 12 , Antonio Febbraro 13 , Donato Natale 14 , Massimo Di Maio 1,16 , Daniela Califano 1 , Giosue  Scognamiglio 1 , Domenica Lorusso 7 , Silvana Canevari 7 , Simona Losito 1 , Ciro Gallo 4,** and Sandro Pignata 1,** 1 Istituto Nazionale per lo Studio e la Cura dei Tumor…

0301 basic medicinemedicine.medical_specialtyLiposomal Doxorubicinovarian cancer; phase 3 clinical trial; predictive factors; pACC; DNA-PKDNA-Activated Protein KinaseDisease-Free Survivalpredictive factorDNA-PK03 medical and health scienceschemistry.chemical_compound0302 clinical medicineOvarian cancerPhase 3 clinical trialAntineoplastic Combined Chemotherapy ProtocolsOverall survivalMedicineHumansDNA-PK; ovarian cancer; pACC; phase 3 clinical trial; predictive factorsGynecologyOvarian NeoplasmsAdvanced ovarian cancerphase 3 clinical trialbusiness.industrySignificant differenceDNA-PK; Ovarian cancer; PACC; Phase 3 clinical trial; Predictive factors; Antineoplastic Combined Chemotherapy Protocols; DNA-Activated Protein Kinase; Disease-Free Survival; Female; Humans; Ovarian Neoplasms; Prognosismedicine.diseasePrognosisPredictive valuePACCCarboplatinhumanitiesFirst line treatmentovarian cancer030104 developmental biologyOncologychemistry030220 oncology & carcinogenesisFemalebusinessOvarian cancerPredictive factorsResearch PaperpACC
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Lipoprotein(a) Levels in Patients With Abdominal Aortic Aneurysm

2016

Circulating markers relevant to the development of abdominal aortic aneurysm (AAA) are currently required. Lipoprotein(a), Lp(a), is considered a candidate marker associated with the presence of AAA. The present meta-analysis aimed to evaluate the association between circulating Lp(a) levels and the presence of AAA. The PubMed-based search was conducted up to April 30, 2015, to identify the studies focusing on Lp(a) levels in patients with AAA and controls. Quantitative data synthesis was performed using a random effects model, with standardized mean difference (SMD) and 95% confidence interval (CI) as summary statistics. Overall, 9 studies were identified. After a combined analysis, patie…

0301 basic medicinemedicine.medical_specialtymacromolecular substances030204 cardiovascular system & hematologyGastroenterology03 medical and health sciences0302 clinical medicineInternal medicineMedicineIn patientcardiovascular diseasesbiologybusiness.industryLipoprotein(a)medicine.diseaseConfidence intervalAbdominal aortic aneurysmSurgery030104 developmental biologyStrictly standardized mean differenceMeta-analysiscardiovascular systembiology.proteinBiomarker (medicine)Cardiology and Cardiovascular MedicinebusinessLipoproteinAngiology
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